CN105069324B - 用于检测β球蛋白基因的变异的微阵列及其检测方法 - Google Patents

用于检测β球蛋白基因的变异的微阵列及其检测方法 Download PDF

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CN105069324B
CN105069324B CN201510428094.7A CN201510428094A CN105069324B CN 105069324 B CN105069324 B CN 105069324B CN 201510428094 A CN201510428094 A CN 201510428094A CN 105069324 B CN105069324 B CN 105069324B
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CN105069324A (zh
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外川直之
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Mitsubishi Kasei Corp
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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CN201510428094.7A 2012-03-29 2013-03-28 用于检测β球蛋白基因的变异的微阵列及其检测方法 Expired - Fee Related CN105069324B (zh)

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JP2012-077394 2012-03-29
JP2012077394 2012-03-29
CN201380017558.4A CN104204227B (zh) 2012-03-29 2013-03-28 用于检测β球蛋白基因的变异的微阵列及其检测方法

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CN201380017558.4A Expired - Fee Related CN104204227B (zh) 2012-03-29 2013-03-28 用于检测β球蛋白基因的变异的微阵列及其检测方法
CN201610306087.4A Withdrawn CN105969848A (zh) 2012-03-29 2013-03-28 用于检测β球蛋白基因的变异的探针

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CN201610306087.4A Withdrawn CN105969848A (zh) 2012-03-29 2013-03-28 用于检测β球蛋白基因的变异的探针

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US (2) US20150184241A1 (ja)
EP (2) EP3138928A1 (ja)
JP (2) JP6269059B2 (ja)
CN (3) CN105069324B (ja)
SG (2) SG10201601806TA (ja)
TW (2) TWI582105B (ja)
WO (1) WO2013147320A1 (ja)

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JP7166638B2 (ja) * 2017-07-24 2022-11-08 国立研究開発法人農業・食品産業技術総合研究機構 多型検出法
CN109490811B (zh) * 2018-11-23 2021-08-13 国网四川省电力公司 一种倒立式电流互感器的油压监测方法
CN111321211A (zh) * 2018-12-14 2020-06-23 北京大学深圳医院 人β地中海贫血基因分型检测的试剂及检测方法
CN110093413A (zh) * 2019-04-09 2019-08-06 深圳市卫生健康发展研究中心 检测β地中海贫血的引物组和试剂盒
CN111733232A (zh) * 2020-07-02 2020-10-02 南京艾迪康医学检验所有限公司 检测hbb基因突变的引物、方法和试剂盒
CN112646872A (zh) * 2020-11-24 2021-04-13 阅尔基因技术（苏州）有限公司 一种检测α-地贫和β-地贫点突变的方法
WO2023283838A1 (zh) * 2021-07-14 2023-01-19 天津华大医学检验所有限公司 用于镰刀型细胞贫血症检测的组合物、试剂盒及应用

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CN101657549A (zh) * 2007-02-06 2010-02-24 生物梅里埃有限公司 用于鉴别单核苷酸多态性（snp）的方法

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JPH11108928A (ja) 1997-10-01 1999-04-23 Dainakomu:Kk 生体高分子配列シートの製造方法
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EP1669902A2 (en) * 2004-11-23 2006-06-14 Agilent Technologies, Inc. Probe design methods and microarrays
CN101657549A (zh) * 2007-02-06 2010-02-24 生物梅里埃有限公司 用于鉴别单核苷酸多态性（snp）的方法
CN101354344A (zh) * 2007-07-27 2009-01-28 上海主健生物工程有限公司 遗传信息及健康评估管理

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Publication number Publication date
TW201619182A (zh) 2016-06-01
TWI582105B (zh) 2017-05-11
EP2832863A4 (en) 2016-02-24
SG11201406010QA (en) 2014-11-27
US20150184241A1 (en) 2015-07-02
EP3138928A1 (en) 2017-03-08
JPWO2013147320A1 (ja) 2015-12-14
CN105969848A (zh) 2016-09-28
CN104204227A (zh) 2014-12-10
US20190040468A1 (en) 2019-02-07
EP2832863A1 (en) 2015-02-04
CN104204227B (zh) 2016-09-07
TW201345919A (zh) 2013-11-16
JP6269746B2 (ja) 2018-01-31
CN105069324A (zh) 2015-11-18
SG10201601806TA (en) 2016-04-28
JP6269059B2 (ja) 2018-01-31
TWI619723B (zh) 2018-04-01
WO2013147320A1 (ja) 2013-10-03
JP2017045451A (ja) 2017-03-02

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