SG11201406010QA - MICROARRAY FOR DETECTION OF MUTATIONS IN β-GLOBIN GENES AND DETECTION METHOD THEREOF - Google Patents

MICROARRAY FOR DETECTION OF MUTATIONS IN β-GLOBIN GENES AND DETECTION METHOD THEREOF

Info

Publication number
SG11201406010QA
SG11201406010QA SG11201406010QA SG11201406010QA SG11201406010QA SG 11201406010Q A SG11201406010Q A SG 11201406010QA SG 11201406010Q A SG11201406010Q A SG 11201406010QA SG 11201406010Q A SG11201406010Q A SG 11201406010QA SG 11201406010Q A SG11201406010Q A SG 11201406010QA
Authority
SG
Singapore
Prior art keywords
detection
microarray
mutations
globin genes
detection method
Prior art date
Application number
SG11201406010QA
Inventor
Naoyuki Togawa
Original Assignee
Mitsubishi Rayon Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Rayon Co filed Critical Mitsubishi Rayon Co
Publication of SG11201406010QA publication Critical patent/SG11201406010QA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG11201406010QA 2012-03-29 2013-03-28 MICROARRAY FOR DETECTION OF MUTATIONS IN β-GLOBIN GENES AND DETECTION METHOD THEREOF SG11201406010QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012077394 2012-03-29
PCT/JP2013/060261 WO2013147320A1 (en) 2012-03-29 2013-03-28 MICROARRAY FOR DETECTION OF MUTATIONS IN β-GLOBIN GENES AND DETECTION METHOD THEREOF

Publications (1)

Publication Number Publication Date
SG11201406010QA true SG11201406010QA (en) 2014-11-27

Family

ID=49260550

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201406010QA SG11201406010QA (en) 2012-03-29 2013-03-28 MICROARRAY FOR DETECTION OF MUTATIONS IN β-GLOBIN GENES AND DETECTION METHOD THEREOF
SG10201601806TA SG10201601806TA (en) 2012-03-29 2013-03-28 Microarray for detection of mutations in beta-globin genes and detection method thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201601806TA SG10201601806TA (en) 2012-03-29 2013-03-28 Microarray for detection of mutations in beta-globin genes and detection method thereof

Country Status (7)

Country Link
US (2) US20150184241A1 (en)
EP (2) EP3138928A1 (en)
JP (2) JP6269059B2 (en)
CN (3) CN105969848A (en)
SG (2) SG11201406010QA (en)
TW (2) TWI582105B (en)
WO (1) WO2013147320A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019022018A1 (en) * 2017-07-24 2019-01-31 国立研究開発法人農業・食品産業技術総合研究機構 Polymorphism detection method
CN109490811B (en) * 2018-11-23 2021-08-13 国网四川省电力公司 Oil pressure monitoring method of inverted current transformer
CN111321211A (en) * 2018-12-14 2020-06-23 北京大学深圳医院 Reagent and method for genotyping and detecting human β thalassemia
CN110093413A (en) * 2019-04-09 2019-08-06 深圳市卫生健康发展研究中心 Detect the primer sets and kit of beta Thalassemia
CN111733232A (en) * 2020-07-02 2020-10-02 南京艾迪康医学检验所有限公司 Primer, method and kit for detecting HBB gene mutation
CN112646872A (en) * 2020-11-24 2021-04-13 阅尔基因技术（苏州）有限公司 Method for detecting alpha-thalassemia and beta-thalassemia point mutation
WO2023283838A1 (en) * 2021-07-14 2023-01-19 天津华大医学检验所有限公司 Composition for detecting sickle-cell disease, kit, and application

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US5220004A (en) * 1991-05-07 1993-06-15 Cetus Corporation Methods and reagents for G -65 -globin typing
FR2749308B1 (en) * 1996-06-03 1998-07-24 Bio Merieux NUCLEOTIDE PROBES AND METHOD FOR DETERMINING THE HLA DQB1 TYPE
JPH11108928A (en) 1997-10-01 1999-04-23 Dainakomu:Kk Manufacture of biopolymer arranged sheet
CA2369524A1 (en) * 1999-04-27 2000-11-02 University Of Chicago Nucleotide extension on a microarray of gel-immobilized primers
US7013221B1 (en) * 1999-07-16 2006-03-14 Rosetta Inpharmatics Llc Iterative probe design and detailed expression profiling with flexible in-situ synthesis arrays
JP4404328B2 (en) 1999-08-26 2010-01-27 三菱レイヨン株式会社 Method for producing biopolymer array flake
US20030096986A1 (en) * 2001-10-25 2003-05-22 Affymetrix, Incorporated Methods and computer software products for selecting nucleic acid probes
WO2002062817A1 (en) 2001-02-08 2002-08-15 Mitsubishi Rayon Co., Ltd. Process for producing vinylated nucleic acid
US7858301B2 (en) * 2003-05-07 2010-12-28 Bioarray Solutions, Ltd. Method of probe design for nucleic acid analysis by multiplexed hybridization
WO2004104172A2 (en) * 2003-05-15 2004-12-02 Bioarray Solutions, Ltd. Hybridization-mediated analysis of polymorphisms
JP2005000127A (en) * 2003-06-13 2005-01-06 Hitachi Software Eng Co Ltd Polymorphism detection method
WO2005001091A1 (en) * 2003-06-27 2005-01-06 Olympus Corporation Probe set for detecting mutation and polymorphism in nucleic acid, dna array having the same immobilized thereon and method of detecting mutation and polymorphism in nucleic acid using the same
ITRM20040081A1 (en) * 2004-02-13 2004-05-13 Biochemical Systems Internat OLIGONUCLEOTIDIC PROBES FOR DIAGNOSIS OF THE DIFFERENT FORMS OF BETA-TALASSEMIA AND RELATED METHODS AND DIAGNOSTIC KITS.
US7374927B2 (en) * 2004-05-03 2008-05-20 Affymetrix, Inc. Methods of analysis of degraded nucleic acid samples
US20050282174A1 (en) * 2004-06-19 2005-12-22 Webb Peter G Methods and systems for selecting nucleic acid probes for microarrays
EP1778876A2 (en) * 2004-06-30 2007-05-02 Applera Corporation Controls for determining reaction performance in polynucleotide sequence detection assays
JPWO2006033484A1 (en) * 2004-09-24 2008-05-15 国立大学法人九州大学 Nucleic acid microarray, nucleic acid probe design method, and gene detection method
AU2005286084C1 (en) * 2004-09-24 2011-11-24 Ingeneus Inc. Genomic assay
US20060110744A1 (en) * 2004-11-23 2006-05-25 Sampas Nicolas M Probe design methods and microarrays for comparative genomic hybridization and location analysis
KR101063037B1 (en) * 2005-12-08 2011-09-07 세키스이 메디칼 가부시키가이샤 Method for detecting human papilloma virus using nucleic acid amplification and nucleic acid chain immobilization carrier
CN101336301A (en) * 2006-01-05 2008-12-31 西蒙斯单倍体有限公司 Microarray methods
EP1956097A1 (en) * 2007-02-06 2008-08-13 bioMerieux B.V. Method for discriminating single nucleotide polymorphisms (SNPs)
CN101354344A (en) * 2007-07-27 2009-01-28 上海主健生物工程有限公司 Genetic information and health evaluating management
US20110212991A1 (en) * 2007-09-11 2011-09-01 Roche Molecular Systems, Inc. Diagnostic Test for Susceptibility to B-RAF Kinase Inhibitors
CN102220411A (en) * 2010-04-16 2011-10-19 中山大学达安基因股份有限公司 Kit for integrated detection of alpha and beta mutant type thalassemias
CN102277419B (en) * 2011-04-06 2012-11-21 广东省妇幼保健院 Method, kit and application for diagnosing thalassemia based on liquid phase chip system

Also Published As

Publication number Publication date
CN105969848A (en) 2016-09-28
EP3138928A1 (en) 2017-03-08
EP2832863A4 (en) 2016-02-24
CN104204227A (en) 2014-12-10
TWI582105B (en) 2017-05-11
JPWO2013147320A1 (en) 2015-12-14
TWI619723B (en) 2018-04-01
JP6269059B2 (en) 2018-01-31
SG10201601806TA (en) 2016-04-28
TW201345919A (en) 2013-11-16
CN104204227B (en) 2016-09-07
US20190040468A1 (en) 2019-02-07
JP2017045451A (en) 2017-03-02
TW201619182A (en) 2016-06-01
US20150184241A1 (en) 2015-07-02
CN105069324A (en) 2015-11-18
EP2832863A1 (en) 2015-02-04
JP6269746B2 (en) 2018-01-31
CN105069324B (en) 2018-08-28
WO2013147320A1 (en) 2013-10-03

Similar Documents

Publication Publication Date Title
IL293796A (en) Methods for nucleic acid assembly and high throughput sequencing
IL269097A (en) Systems and methods to detect rare mutations and copy number variation
HK1246372A1 (en) System and methods for detecting genetic variation
HK1253227A1 (en) Systems and methods for epigenetic sequencing
HK1246901A1 (en) Processing and analysis of complex nucleic acid sequence data
EP2922989A4 (en) Methods for standardized sequencing of nucleic acids and uses thereof
HK1211260A1 (en) Method and kit for nucleic acid sequencing
EP2861769A4 (en) Compositions and methods for sensitive mutation detection in nucleic acid molecules
ZA201407798B (en) Inhibitors of hepatitis b virus covalently closed circular dna formation and their method of use
SG11201406010QA (en) MICROARRAY FOR DETECTION OF MUTATIONS IN β-GLOBIN GENES AND DETECTION METHOD THEREOF
EP2931319A4 (en) Modified nucleic acid molecules and uses thereof
EP2809767A4 (en) Nucleic acid amplification and detection apparatus and method
HK1205744A1 (en) Identification of channelrhodopsin-2 (chop2) mutations and methods of use -2(chop2)
HK1209834A1 (en) Substances detection system and method
EP2723906A4 (en) Method for genome complexity reduction and polymorphism detection
PL2854981T3 (en) Methods of nucleic acid fractionation and detection
EP2803726A4 (en) Standardized reference gene for microrna and use thereof
GB201218460D0 (en) Detection apparatus and method
GB201221124D0 (en) Method of spectral data detection and manipulation
EP2614160A4 (en) Detection of rna-interacting regions in dna
EP2844767A4 (en) Nucleic acid sequencing systems and methods
EP2804957A4 (en) Method of detecting residual genomic dna and a kit thereof
EP2865759A4 (en) Nucleic acid complex and nucleic acid-polysaccharide complex
GB201219976D0 (en) Means and methods for identifying ribosome associated RNA molecules
EP2840137A4 (en) Method for identification and detection of mutant gene using intercalator