CN104805142A - 一种醇脱氢酶在不对称还原反应中的应用 - Google Patents
一种醇脱氢酶在不对称还原反应中的应用 Download PDFInfo
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- CN104805142A CN104805142A CN201510079279.1A CN201510079279A CN104805142A CN 104805142 A CN104805142 A CN 104805142A CN 201510079279 A CN201510079279 A CN 201510079279A CN 104805142 A CN104805142 A CN 104805142A
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106187788A (zh) * | 2016-07-29 | 2016-12-07 | 北京万全德众医药生物技术有限公司 | 盐酸托莫西汀的一种制备方法 |
CN107418980A (zh) * | 2017-06-16 | 2017-12-01 | 义乌市欣邦生物科技有限公司 | 一种r‑3,5‑双三氟甲基苯乙醇的清洁生产方法 |
CN108949707A (zh) * | 2017-05-24 | 2018-12-07 | 武汉大学 | 一种热稳定性提高的醇脱氢酶突变体 |
CN109053479A (zh) * | 2018-10-15 | 2018-12-21 | 兆科药业(合肥)有限公司 | 一种季胺内盐的合成方法 |
CN109706191A (zh) * | 2019-01-21 | 2019-05-03 | 南京欧信医药技术有限公司 | 一种托莫西汀中间体的酶催化合成方法 |
CN112851470A (zh) * | 2021-01-19 | 2021-05-28 | 温州大学 | 一种合成手性二级醇化合物的方法 |
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CN101316932A (zh) * | 2005-12-23 | 2008-12-03 | 巴斯夫欧洲公司 | 制备旋光的(1s)-3-氯-1-(2-噻酚基)-丙-1-醇的方法 |
US20110319664A1 (en) * | 2010-06-29 | 2011-12-29 | Bo-Fong Chen | Method for preparing atomoxetine |
CN103131734A (zh) * | 2013-02-21 | 2013-06-05 | 凯莱英医药集团(天津)股份有限公司 | 应用两种醇脱氢酶还原酮类化合物的方法 |
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2015
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CN101316932A (zh) * | 2005-12-23 | 2008-12-03 | 巴斯夫欧洲公司 | 制备旋光的(1s)-3-氯-1-(2-噻酚基)-丙-1-醇的方法 |
US20110319664A1 (en) * | 2010-06-29 | 2011-12-29 | Bo-Fong Chen | Method for preparing atomoxetine |
CN103131734A (zh) * | 2013-02-21 | 2013-06-05 | 凯莱英医药集团(天津)股份有限公司 | 应用两种醇脱氢酶还原酮类化合物的方法 |
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SYLVAIN BROUSSY ET AL: "Enantioselective,ketoreductase-based entry into pharmaceutical building blocks:ethanol as tunable nicotinamide reductant", 《ORGANIC LETTERS》 * |
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Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106187788A (zh) * | 2016-07-29 | 2016-12-07 | 北京万全德众医药生物技术有限公司 | 盐酸托莫西汀的一种制备方法 |
CN108949707A (zh) * | 2017-05-24 | 2018-12-07 | 武汉大学 | 一种热稳定性提高的醇脱氢酶突变体 |
CN108949707B (zh) * | 2017-05-24 | 2020-07-10 | 武汉大学 | 一种热稳定性提高的醇脱氢酶突变体 |
CN107418980A (zh) * | 2017-06-16 | 2017-12-01 | 义乌市欣邦生物科技有限公司 | 一种r‑3,5‑双三氟甲基苯乙醇的清洁生产方法 |
CN107418980B (zh) * | 2017-06-16 | 2020-06-09 | 义乌市欣邦生物科技有限公司 | 一种r-3,5-双三氟甲基苯乙醇的清洁生产方法 |
CN109053479A (zh) * | 2018-10-15 | 2018-12-21 | 兆科药业(合肥)有限公司 | 一种季胺内盐的合成方法 |
CN109053479B (zh) * | 2018-10-15 | 2021-09-07 | 兆科药业(合肥)有限公司 | 一种季胺内盐的合成方法 |
CN109706191A (zh) * | 2019-01-21 | 2019-05-03 | 南京欧信医药技术有限公司 | 一种托莫西汀中间体的酶催化合成方法 |
CN109706191B (zh) * | 2019-01-21 | 2022-09-09 | 南京欧信医药技术有限公司 | 一种托莫西汀中间体的酶催化合成方法 |
CN112851470A (zh) * | 2021-01-19 | 2021-05-28 | 温州大学 | 一种合成手性二级醇化合物的方法 |
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