CN104628704B - 一种泮托拉唑钠化合物的新晶型及其制备方法 - Google Patents
一种泮托拉唑钠化合物的新晶型及其制备方法 Download PDFInfo
- Publication number
- CN104628704B CN104628704B CN201510075979.3A CN201510075979A CN104628704B CN 104628704 B CN104628704 B CN 104628704B CN 201510075979 A CN201510075979 A CN 201510075979A CN 104628704 B CN104628704 B CN 104628704B
- Authority
- CN
- China
- Prior art keywords
- pantoprazole sodium
- crystal
- preparation
- product
- suspension
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
Claims (9)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510075979.3A CN104628704B (zh) | 2015-02-12 | 2015-02-12 | 一种泮托拉唑钠化合物的新晶型及其制备方法 |
US15/304,861 US20170197937A1 (en) | 2015-02-12 | 2015-11-20 | New crystal form of pantoprazole sodium compound and preparation method therefor |
PCT/CN2015/095231 WO2016127684A1 (zh) | 2015-02-12 | 2015-11-20 | 一种泮托拉唑钠化合物新晶型及其制剂和制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510075979.3A CN104628704B (zh) | 2015-02-12 | 2015-02-12 | 一种泮托拉唑钠化合物的新晶型及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104628704A CN104628704A (zh) | 2015-05-20 |
CN104628704B true CN104628704B (zh) | 2015-12-30 |
Family
ID=53207995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510075979.3A Active CN104628704B (zh) | 2015-02-12 | 2015-02-12 | 一种泮托拉唑钠化合物的新晶型及其制备方法 |
Country Status (3)
Country | Link |
---|---|
US (1) | US20170197937A1 (zh) |
CN (1) | CN104628704B (zh) |
WO (1) | WO2016127684A1 (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104876910A (zh) * | 2015-05-26 | 2015-09-02 | 苗怡文 | 一种治疗胃病的药物泮托拉唑钠化合物及其制备方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101475561A (zh) * | 2009-01-21 | 2009-07-08 | 海南美大制药有限公司 | 一种泮托拉唑及其盐的合成方法 |
CN101514198A (zh) * | 2009-03-31 | 2009-08-26 | 张锡芬 | 一种泮托拉唑钠化合物及其制法 |
CN102887886A (zh) * | 2012-10-26 | 2013-01-23 | 扬子江药业集团江苏海慈生物药业有限公司 | 一种泮托拉唑钠的制备方法 |
CN103058999A (zh) * | 2013-01-29 | 2013-04-24 | 黄明芳 | 一种新型泮托拉唑钠化合物及其药物组合物 |
CN103232438A (zh) * | 2013-05-09 | 2013-08-07 | 成都天台山制药有限公司 | 泮托拉唑钠和制法 |
CN104262326A (zh) * | 2014-09-14 | 2015-01-07 | 严白双 | 一种泮托拉唑钠的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2510849A1 (en) * | 2002-12-19 | 2004-07-08 | Teva Pharmaceutical Industries Ltd | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates |
AU2003241150A1 (en) * | 2003-05-06 | 2004-11-26 | Hetero Drugs Limited | Novel polymorphs of pantoprazole sodium |
CN102796078B (zh) * | 2012-08-24 | 2014-10-29 | 杭州澳亚生物技术有限公司 | 一种泮托拉唑化合物、制备方法及其药物制剂 |
CN103709140A (zh) * | 2013-10-11 | 2014-04-09 | 寿光富康制药有限公司 | 泮托拉唑钠的晶体及其制备方法 |
-
2015
- 2015-02-12 CN CN201510075979.3A patent/CN104628704B/zh active Active
- 2015-11-20 US US15/304,861 patent/US20170197937A1/en not_active Abandoned
- 2015-11-20 WO PCT/CN2015/095231 patent/WO2016127684A1/zh active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101475561A (zh) * | 2009-01-21 | 2009-07-08 | 海南美大制药有限公司 | 一种泮托拉唑及其盐的合成方法 |
CN101514198A (zh) * | 2009-03-31 | 2009-08-26 | 张锡芬 | 一种泮托拉唑钠化合物及其制法 |
CN102887886A (zh) * | 2012-10-26 | 2013-01-23 | 扬子江药业集团江苏海慈生物药业有限公司 | 一种泮托拉唑钠的制备方法 |
CN103058999A (zh) * | 2013-01-29 | 2013-04-24 | 黄明芳 | 一种新型泮托拉唑钠化合物及其药物组合物 |
CN103232438A (zh) * | 2013-05-09 | 2013-08-07 | 成都天台山制药有限公司 | 泮托拉唑钠和制法 |
CN104262326A (zh) * | 2014-09-14 | 2015-01-07 | 严白双 | 一种泮托拉唑钠的制备方法 |
Also Published As
Publication number | Publication date |
---|---|
CN104628704A (zh) | 2015-05-20 |
US20170197937A1 (en) | 2017-07-13 |
WO2016127684A1 (zh) | 2016-08-18 |
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CB03 | Change of inventor or designer information |
Inventor after: Hao Hongxun Inventor after: Xie Chuang Inventor after: Wang Zhao Inventor after: Tao Linggang Inventor after: Jiang Chen Inventor after: Wang Yongli Inventor after: Wang Jingkang Inventor after: Lv Jun Inventor after: Yin Qiuxiang Inventor after: Hou Baohong Inventor after: Xu Zhao Inventor before: Hao Hongxun Inventor before: Wang Zhao Inventor before: Tao Linggang Inventor before: Jiang Chen Inventor before: Wang Yongli Inventor before: Lv Jun Inventor before: Yin Qiuxiang Inventor before: Hou Baohong Inventor before: Xu Zhao Inventor before: Xie Chuang |
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GR01 | Patent grant |