CN104520270A - 视黄醇酯的酯交换方法 - Google Patents

视黄醇酯的酯交换方法 Download PDF

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Publication number
CN104520270A
CN104520270A CN201380041720.6A CN201380041720A CN104520270A CN 104520270 A CN104520270 A CN 104520270A CN 201380041720 A CN201380041720 A CN 201380041720A CN 104520270 A CN104520270 A CN 104520270A
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CN
China
Prior art keywords
transesterification
formula
compound
reaction
alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380041720.6A
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English (en)
Chinese (zh)
Inventor
沃纳尔·邦拉蒂
亚历克斯·贾俄
克劳德·斯特里特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
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DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48918423&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN104520270(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Priority to CN201810319627.1A priority Critical patent/CN108558724A/zh
Publication of CN104520270A publication Critical patent/CN104520270A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
CN201380041720.6A 2012-08-07 2013-08-07 视黄醇酯的酯交换方法 Pending CN104520270A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810319627.1A CN108558724A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12179461.4 2012-08-07
EP12179461 2012-08-07
PCT/EP2013/066558 WO2014023772A1 (en) 2012-08-07 2013-08-07 Transesterification process of retinol esters

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201810319627.1A Division CN108558724A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法

Publications (1)

Publication Number Publication Date
CN104520270A true CN104520270A (zh) 2015-04-15

Family

ID=48918423

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201380041720.6A Pending CN104520270A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法
CN201810319627.1A Pending CN108558724A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201810319627.1A Pending CN108558724A (zh) 2012-08-07 2013-08-07 视黄醇酯的酯交换方法

Country Status (6)

Country Link
US (1) US9371279B2 (https=)
EP (1) EP2882709B1 (https=)
CN (2) CN104520270A (https=)
EA (1) EA027565B1 (https=)
IN (1) IN2015DN00725A (https=)
WO (1) WO2014023772A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106544391A (zh) * 2016-11-25 2017-03-29 厦门金达威维生素有限公司 酶催化制备维生素a棕榈酸酯的方法
CN108623507A (zh) * 2017-03-15 2018-10-09 四川海思科制药有限公司 维生素a棕榈酸酯的制备方法
CN112522331A (zh) * 2020-12-09 2021-03-19 上海克琴科技有限公司 一种生物酶催化的羟基频哪酮视黄酸酯的合成方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023520137A (ja) * 2020-03-31 2023-05-16 ディーエスエム アイピー アセッツ ビー．ブイ． テルペノイド中間体の生成方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2971966A (en) * 1957-08-30 1961-02-14 Pfizer & Co C Process of preparing vitamin a esters
US3287382A (en) * 1962-04-27 1966-11-22 Philips Corp Vitamin a acid ester of vitamin a
WO2004044212A1 (en) * 2002-11-11 2004-05-27 Unilever Plc Method of producing retinyl esters
CN101553574A (zh) * 2006-10-06 2009-10-07 伊士曼化工公司 制备视黄酯的方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2971966A (en) * 1957-08-30 1961-02-14 Pfizer & Co C Process of preparing vitamin a esters
US3287382A (en) * 1962-04-27 1966-11-22 Philips Corp Vitamin a acid ester of vitamin a
WO2004044212A1 (en) * 2002-11-11 2004-05-27 Unilever Plc Method of producing retinyl esters
CN101553574A (zh) * 2006-10-06 2009-10-07 伊士曼化工公司 制备视黄酯的方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MILAN SOUKUP 等: "PREPARATION OF (7z)-AND (7z,11z)-VITAMIN A", 《TETRAHEDRON LETTERS》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106544391A (zh) * 2016-11-25 2017-03-29 厦门金达威维生素有限公司 酶催化制备维生素a棕榈酸酯的方法
CN106544391B (zh) * 2016-11-25 2019-10-18 厦门金达威维生素有限公司 酶催化制备维生素a棕榈酸酯的方法
CN108623507A (zh) * 2017-03-15 2018-10-09 四川海思科制药有限公司 维生素a棕榈酸酯的制备方法
CN112522331A (zh) * 2020-12-09 2021-03-19 上海克琴科技有限公司 一种生物酶催化的羟基频哪酮视黄酸酯的合成方法
CN112522331B (zh) * 2020-12-09 2024-03-22 上海克琴科技有限公司 一种生物酶催化的羟基频哪酮视黄酸酯的合成方法

Also Published As

Publication number Publication date
EP2882709B1 (en) 2018-06-20
CN108558724A (zh) 2018-09-21
US9371279B2 (en) 2016-06-21
EA027565B1 (ru) 2017-08-31
US20150183734A1 (en) 2015-07-02
EA201500210A1 (ru) 2015-07-30
IN2015DN00725A (https=) 2015-07-10
WO2014023772A1 (en) 2014-02-13
EP2882709A1 (en) 2015-06-17

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Application publication date: 20150415

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