CN104448261B - 高性能高分子量聚l-乳酸合成工艺 - Google Patents

高性能高分子量聚l-乳酸合成工艺 Download PDF

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Publication number
CN104448261B
CN104448261B CN201410765621.9A CN201410765621A CN104448261B CN 104448261 B CN104448261 B CN 104448261B CN 201410765621 A CN201410765621 A CN 201410765621A CN 104448261 B CN104448261 B CN 104448261B
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China
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polymerization
lactic acid
stage
plla
polymerization reaction
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CN201410765621.9A
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Chinese (zh)
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CN104448261A (zh
Inventor
李弘�
张全兴
宗绪鹏
李爱民
黄伟
江伟
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Nanjing University
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Nanjing University
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Priority to PCT/CN2015/081253 priority patent/WO2016090878A1/zh
Priority to JP2016567120A priority patent/JP6343031B2/ja
Priority to US14/854,009 priority patent/US9845377B2/en
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C08G63/823—Preparation processes characterised by the catalyst used for the preparation of polylactones or polylactides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Biological Depolymerization Polymers (AREA)
CN201410765621.9A 2014-12-12 2014-12-12 高性能高分子量聚l-乳酸合成工艺 Expired - Fee Related CN104448261B (zh)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CN201410765621.9A CN104448261B (zh) 2014-12-12 2014-12-12 高性能高分子量聚l-乳酸合成工艺
PCT/CN2015/081253 WO2016090878A1 (zh) 2014-12-12 2015-06-11 高性能高分子量聚l-乳酸合成工艺
JP2016567120A JP6343031B2 (ja) 2014-12-12 2015-06-11 高性能高分子量ポリｌ−乳酸合成プロセス
US14/854,009 US9845377B2 (en) 2014-12-12 2015-09-14 Method for preparing high molecular weight poly-L-lactic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410765621.9A CN104448261B (zh) 2014-12-12 2014-12-12 高性能高分子量聚l-乳酸合成工艺

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CN104448261A CN104448261A (zh) 2015-03-25
CN104448261B true CN104448261B (zh) 2016-09-14

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US (1) US9845377B2 (enExample)
JP (1) JP6343031B2 (enExample)
CN (1) CN104448261B (enExample)
WO (1) WO2016090878A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104448261B (zh) * 2014-12-12 2016-09-14 南京大学 高性能高分子量聚l-乳酸合成工艺
CN106146817B (zh) * 2015-04-21 2019-04-05 上海浦景化工新材料有限公司 羟基烷酸锌聚酯催化剂，其制备方法以及该催化剂的应用
CN105131259B (zh) * 2015-09-14 2017-05-31 南京大学 生物胍复合体系催化熔融‑固相聚合合成高分子量聚α‑羟基酸
RU2637923C1 (ru) * 2016-11-30 2017-12-08 Общество с ограниченной ответственностью "Медин-Н" Способ получения (со)полимера гликолида и/или лактида для изготовления рассасывающихся хирургических изделий
CN106831700B (zh) * 2017-03-28 2019-05-24 南京大学 一种全绿色封闭循环工艺生产光学纯l-/d-丙交酯的方法
CN107540824B (zh) * 2017-09-21 2019-07-05 南京大学 大分子引发剂暨缩合-开环-固相聚合联用合成超高等规度聚l-/d-乳酸的方法
CN109081909A (zh) * 2018-07-09 2018-12-25 南京大学 一种利用有机双胍催化剂合成聚对苯二甲酸丙二醇酯的工艺
CN110054762B (zh) * 2019-05-29 2021-09-07 南京大学 一种催化丙交酯开环聚合的工艺方法
CN111848692B (zh) * 2020-08-02 2021-03-19 扬州普立特科技发展有限公司 生物质有机胍配合物的制备方法及其催化合成pet或peit聚酯的应用
CN113150254B (zh) * 2021-03-26 2022-07-19 天津科技大学 一种以乳酸水溶液调控制备无毒性聚乳酸的方法
CN114790282B (zh) * 2021-12-30 2023-03-21 康辉新材料科技有限公司 一种纳米微颗粒原位聚合催化剂的制备方法及其应用
CN116393174B (zh) * 2023-04-04 2024-06-21 大连理工大学 一种同时用于制备乙交酯和聚乙交酯的催化剂及制备方法

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
CN1234750C (zh) * 2004-01-08 2006-01-04 南开大学 生物质有机胍化物催化合成医用生物降解材料的工艺方法
CN1241970C (zh) * 2004-03-02 2006-02-15 南开大学 以醋酸有机胍为催化剂合成医用生物降解材料的工艺方法
JP2009001614A (ja) * 2007-06-19 2009-01-08 Musashino Chemical Laboratory Ltd ポリ乳酸ブロック共重合体の製造方法、該製造方法で得られたポリ乳酸ブロック共重合体、およびこれを用いた成形品
CN101367921A (zh) * 2008-10-06 2009-02-18 中国人民解放军第二军医大学 一种丙交酯开环合成聚乳酸的方法
US8507640B2 (en) * 2010-08-19 2013-08-13 International Business Machines Corporation Methods of ring opening polymerization and catalysts therefor
CN102161752B (zh) * 2011-03-14 2013-02-27 南京大学 肌酐催化乳酸缩聚合成医用生物降解性聚乳酸的工艺方法
CN102146155B (zh) * 2011-05-09 2012-11-28 浙江大学宁波理工学院 一种丙交酯的催化聚合方法
CN102295765B (zh) * 2011-06-30 2012-11-28 南京大学 生物质肌酐催化共缩聚法合成聚乳酸-乙醇酸
CN102329269B (zh) * 2011-06-30 2013-07-17 南京大学 仿生氯化肌酐胍催化缩聚法合成高分子量聚乳酸
CN102675607B (zh) * 2012-05-22 2013-08-14 南京大学 乳酸自催化熔融缩聚—肌酐催化固相缩聚联用法合成高分子量聚乳酸
CN103396535A (zh) * 2013-08-09 2013-11-20 深圳市光华伟业实业有限公司 一种由丙交酯和多元醇合成聚丙交酯多元醇的方法
CN104448261B (zh) * 2014-12-12 2016-09-14 南京大学 高性能高分子量聚l-乳酸合成工艺

Also Published As

Publication number Publication date
JP6343031B2 (ja) 2018-06-13
JP2017507229A (ja) 2017-03-16
CN104448261A (zh) 2015-03-25
WO2016090878A1 (zh) 2016-06-16
US9845377B2 (en) 2017-12-19
US20160168316A1 (en) 2016-06-16

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