CN104271119B - 用于稳定干燥的生物材料的方法和组合物 - Google Patents
用于稳定干燥的生物材料的方法和组合物 Download PDFInfo
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| US201261606577P | 2012-03-05 | 2012-03-05 | |
| US61/606,577 | 2012-03-05 | ||
| EP12158086.4 | 2012-03-05 | ||
| EP12158086 | 2012-03-05 | ||
| PCT/NL2013/050139 WO2013133702A1 (en) | 2012-03-05 | 2013-03-05 | Methods and compositions for stabilizing dried biological materials |
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| CN104271119A CN104271119A (zh) | 2015-01-07 |
| CN104271119B true CN104271119B (zh) | 2018-07-10 |
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| CN104274827B (zh) * | 2013-07-01 | 2020-07-14 | 上海贺普药业股份有限公司 | 贺普拉肽的制剂 |
| US10538785B2 (en) | 2013-12-23 | 2020-01-21 | Renaud Vaillant | Lyophilized lentiviral vector particles, compositions and methods |
| CA3027454A1 (en) * | 2016-06-16 | 2017-12-21 | Janssen Vaccines & Prevention B.V. | Hiv vaccine formulation |
| EP3586905B1 (en) * | 2017-02-24 | 2023-07-26 | Hisamitsu Pharmaceutical Co., Inc. | Method for producing microneedle device |
| US20200085941A1 (en) * | 2017-04-28 | 2020-03-19 | Universal Stabilization Technologies, Inc. | Antigenic thermostable polio vaccines & related methods |
| US11400051B2 (en) * | 2017-07-11 | 2022-08-02 | Universal Stabilization Technologies, Inc. | Method for preserving biopharmaceuticals |
| CN111166891B (zh) * | 2018-11-13 | 2022-04-05 | 中国药科大学 | 甘露醇共晶辅料及其制备方法和用途 |
| CN112111609A (zh) * | 2020-10-29 | 2020-12-22 | 上海伯杰医疗科技有限公司 | 一种肠道病毒通用型核酸检测试剂盒 |
| CN114748615A (zh) * | 2022-04-29 | 2022-07-15 | 成都安永鼎业生物技术有限公司 | 一种治疗用重组卡介苗的冻干制剂及其制备方法和用途 |
| CN115089864B (zh) * | 2022-07-14 | 2023-12-29 | 复旦大学 | 一种使用冷冻干燥技术制备可溶性微针贴片的方法 |
| CN116763914B (zh) * | 2023-02-06 | 2024-02-23 | 广东永顺生物制药股份有限公司 | 猪瘟、高致病性猪繁殖与呼吸综合征二联耐热保护剂活疫苗及其制备方法 |
| CN117482072A (zh) * | 2023-11-17 | 2024-02-02 | 上海市浦东新区公利医院(第二军医大学附属公利医院) | 山梨糖醇在制备治疗呼吸道合胞病毒所致疾病的药物中的应用 |
Citations (1)
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| US4500512A (en) * | 1981-05-13 | 1985-02-19 | Institut Pasteur | Stabilizing agents for live viruses for preparing vaccines, and stabilized vaccines containing said stabilizing agents |
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| JPH0761955B2 (ja) * | 1988-04-28 | 1995-07-05 | 国立予防衛生研究所長 | 凍結乾燥ａ型肝炎ワクチン |
| DK0939648T3 (da) * | 1996-09-26 | 2008-02-11 | Merck & Co Inc | Rotavirusvaccineformuleringer |
| US6210683B1 (en) * | 1997-09-05 | 2001-04-03 | Merck & Co., Inc. | Stabilizers containing recombinant human serum albumin for live virus vaccines |
| JP5118798B2 (ja) * | 2000-03-07 | 2013-01-16 | メルク・シャープ・エンド・ドーム・コーポレイション | アデノウイルス製剤 |
| BR0111494A (pt) * | 2000-06-08 | 2004-01-13 | Powderject Vaccines Inc | Pó de livre escoamento formador de gel adequado para uso como uma vacina, processo para a preparação do mesmo, receptáculo de dosagem para uma seringa sem agulha, seringa sem agulha, composição de vacina, método para vacinação de um indivìduo, pó adequado para uso como uma vacina, e, processo para a preparação do mesmo |
| GB0020089D0 (en) | 2000-08-15 | 2000-10-04 | Smithkline Beecham Biolog | Vaccine Composition |
| FR2814957B1 (fr) * | 2000-10-06 | 2002-12-20 | Aventis Pasteur | Composition vaccinale et procede de stabilisation |
| MXPA06006947A (es) * | 2003-12-17 | 2007-01-26 | Wyeth Corp | Metodos para producir virus de almacenamiento estable y composiciones inmunogenicas de estos. |
| DK1699919T3 (en) | 2003-12-24 | 2017-03-20 | De Staat Der Nederlanden Vertegenwoordigd Door De Mini Van Volksgezondheid Welzijn En Sport | RESPIRATORY SYNCYTIAL VIRUS WITH A GENOMIC DEFICIENCY COMPLETED IN TRANS |
| GB0503337D0 (en) * | 2005-02-17 | 2005-03-23 | Glaxosmithkline Biolog Sa | Compositions |
| TWI398272B (zh) * | 2005-03-08 | 2013-06-11 | Intervet Int Bv | 化學定義的安定劑 |
| MX2007015476A (es) * | 2005-06-14 | 2008-02-25 | Amgen Inc | Formulaciones de proteina autoamortiguadoras. |
| EA036522B1 (ru) * | 2009-12-11 | 2020-11-19 | Пфайзер Инк. | Фармацевтическая композиция, пригодная для лиофилизации, содержащая множество терапевтических частиц |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4500512A (en) * | 1981-05-13 | 1985-02-19 | Institut Pasteur | Stabilizing agents for live viruses for preparing vaccines, and stabilized vaccines containing said stabilizing agents |
Non-Patent Citations (1)
| Title |
|---|
| heat stability of the lyophilized sabin poliovaccine;Hiroshi Shiomi,etal;《Jpn.J.Infect.Dis.》;20031231;70-72 * |
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| US10335479B2 (en) | 2019-07-02 |
| WO2013133702A1 (en) | 2013-09-12 |
| EP2822540B1 (en) | 2020-04-08 |
| ZA201407198B (en) | 2016-02-24 |
| AU2013228096A1 (en) | 2014-09-11 |
| US20180055924A1 (en) | 2018-03-01 |
| AU2013228096B2 (en) | 2017-07-13 |
| CN104271119A (zh) | 2015-01-07 |
| JP2015509529A (ja) | 2015-03-30 |
| BR112014020930A2 (pt) | 2017-06-27 |
| JP6253161B2 (ja) | 2017-12-27 |
| CA2865551A1 (en) | 2013-09-12 |
| KR102108876B1 (ko) | 2020-05-12 |
| KR20150008848A (ko) | 2015-01-23 |
| EP2822540A1 (en) | 2015-01-14 |
| CA2865551C (en) | 2021-01-12 |
| US20150030629A1 (en) | 2015-01-29 |
| US9827303B2 (en) | 2017-11-28 |
| IN2014MN01714A (enrdf_load_stackoverflow) | 2015-05-29 |
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