CN104011203A - 视网膜变性疾病的治疗方法 - Google Patents
视网膜变性疾病的治疗方法 Download PDFInfo
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- CN104011203A CN104011203A CN201280049453.2A CN201280049453A CN104011203A CN 104011203 A CN104011203 A CN 104011203A CN 201280049453 A CN201280049453 A CN 201280049453A CN 104011203 A CN104011203 A CN 104011203A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/20—Milk; Whey; Colostrum
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Developmental Biology & Embryology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11176713.3 | 2011-08-05 | ||
| EP11176713A EP2554662A1 (en) | 2011-08-05 | 2011-08-05 | Methods of treatment of retinal degeneration diseases |
| PCT/EP2012/065327 WO2013020945A1 (en) | 2011-08-05 | 2012-08-06 | Methods of treatment of retinal degeneration diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104011203A true CN104011203A (zh) | 2014-08-27 |
Family
ID=46826437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280049453.2A Pending CN104011203A (zh) | 2011-08-05 | 2012-08-06 | 视网膜变性疾病的治疗方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20140199277A1 (enExample) |
| EP (2) | EP2554662A1 (enExample) |
| JP (1) | JP2014527407A (enExample) |
| KR (1) | KR20140068936A (enExample) |
| CN (1) | CN104011203A (enExample) |
| AR (1) | AR087471A1 (enExample) |
| AU (1) | AU2012293681A1 (enExample) |
| BR (1) | BR112014002718A8 (enExample) |
| CA (1) | CA2844106A1 (enExample) |
| CO (1) | CO7081142A2 (enExample) |
| IL (1) | IL230830A0 (enExample) |
| MX (1) | MX2014001475A (enExample) |
| RU (1) | RU2014108478A (enExample) |
| SG (1) | SG2014008080A (enExample) |
| WO (1) | WO2013020945A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108603167A (zh) * | 2015-09-15 | 2018-09-28 | 思特科技公司 | 使用其中引入nanog的源自羊水胎儿的间充质干细胞制备用于促进毛发生长的组合物的方法 |
| CN109414416A (zh) * | 2016-07-07 | 2019-03-01 | 国民大学校产学协力团 | 倍半萜衍生物的新用途 |
| CN110267972A (zh) * | 2016-11-06 | 2019-09-20 | 纳秒示波器科技有限公司 | 由多特征视蛋白进行的用于视力恢复的光学调制以及其其他应用 |
| CN110706164A (zh) * | 2019-09-03 | 2020-01-17 | 北京爱博同心医学科技有限公司 | 基于增强现实的管状视野图像变形显示方法及眼镜 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103889441A (zh) | 2011-09-29 | 2014-06-25 | 伊丽莎白女王在都柏林附近神圣不可分割的三一学院教务长、研究员、学者及董事会其他成员 | 用于治疗退行性视网膜病况的组合物和方法 |
| US11724005B2 (en) | 2014-01-17 | 2023-08-15 | Sumitomo Chemical Company, Limited | Method for manufacturing ciliary margin stem cells |
| SG10201902285SA (en) * | 2014-09-16 | 2019-04-29 | Genzyme Corp | Adeno-associated viral vectors for treating myocilin (myoc) glaucoma |
| RU2578526C1 (ru) * | 2014-12-25 | 2016-03-27 | федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Способ получения органной культуры хороидально-пигментного комплекса из глаза взрослого донора-трупа |
| RU2569481C1 (ru) * | 2014-12-25 | 2015-11-27 | федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Способ получения культуры клеток ретинального пигментного эпителия из глаза взрослого донора-трупа |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| JP7100019B2 (ja) * | 2016-08-19 | 2022-07-12 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 選択的エストロゲン受容体モジュレーター(serm)は、光受容体の変性に対する保護を付与する |
| BR112019022447A2 (pt) | 2017-04-27 | 2020-06-09 | Bober Miroslaw | sistema e método para análise de imagem funduscópica automatizada |
| PE20191811A1 (es) | 2017-05-18 | 2019-12-26 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina como moduladores del receptor de pge2 |
| PE20191814A1 (es) | 2017-05-18 | 2019-12-27 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina como moduladores del receptor de pge2 |
| EP3625223B1 (en) | 2017-05-18 | 2021-08-11 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives |
| JP7065117B2 (ja) | 2017-05-18 | 2022-05-11 | イドーシア ファーマシューティカルズ リミテッド | N-置換インドール誘導体 |
| CN110621671A (zh) | 2017-05-18 | 2019-12-27 | 爱杜西亚药品有限公司 | 作为pge2受体调节剂的苯并呋喃及苯并噻吩衍生物 |
| US20210139844A1 (en) * | 2017-06-15 | 2021-05-13 | University Of North Texas Health Science Center | Reprogramming fibroblasts to retinal cells |
| EP3668487A4 (en) * | 2017-08-20 | 2020-08-26 | The Regents of the University of California | MODULATION OF WNT5A TO TREAT GLAUCOMA |
| WO2019195717A1 (en) * | 2018-04-06 | 2019-10-10 | Icahn School Of Medicine At Mount Sinai | Compositions and methods of treatment of vision loss through generation of rod photoreceptors from müller glial cells |
| WO2020190848A1 (en) * | 2019-03-15 | 2020-09-24 | The Schepens Eye Research Institute, Inc. | Isolation, enrichment and expansion of cone progenitor cells and uses thereof |
| US20230034053A1 (en) * | 2019-09-25 | 2023-02-02 | The Board Of Trustees Of The Leland Stanford Junior University | Metabolic rescue of retinal degeneration |
| KR20210119766A (ko) * | 2020-03-25 | 2021-10-06 | 서울대학교병원 | 인간 배아줄기세포 유래 중간엽 줄기세포를 포함하는 망막색소변성의 예방 또는 치료용 약학적 조성물 |
| KR102655748B1 (ko) * | 2023-06-08 | 2024-04-05 | 충북대학교 산학협력단 | 고포도당 조건에서의 중간엽 줄기세포의 생존율을 증가시키는 방법 |
| KR102655735B1 (ko) * | 2023-06-09 | 2024-04-05 | 충북대학교 산학협력단 | 당뇨성 망막병증의 예방 및 치료를 위한 타크로리무스 전처리 줄기세포 |
| WO2025229177A1 (en) | 2024-05-02 | 2025-11-06 | Idorsia Pharmaceuticals Ltd | Crystalline forms of an n-substituted indole derivative |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050129665A1 (en) * | 2002-07-25 | 2005-06-16 | Martin Friedlander | Isolated lineage negative hematopoietic stem cells and methods of treatment therewith |
| CN1816281A (zh) * | 2003-05-02 | 2006-08-09 | 斯克里普斯研究学院 | 造血干细胞及其治疗新生血管性眼疾的方法 |
| EP2090649A1 (en) * | 2008-02-13 | 2009-08-19 | Fondazione Telethon | Method for reprogramming differentiated cells |
| WO2010029288A2 (en) * | 2008-09-11 | 2010-03-18 | Axordia Limited | Growth factor |
| CN101835891A (zh) * | 2007-06-15 | 2010-09-15 | 加内特生物治疗学股份有限公司 | 运用体外培养增殖的自我更新型集落形成细胞治疗疾病和功能紊乱症 |
| WO2011043591A2 (en) * | 2009-10-06 | 2011-04-14 | Snu R&Db Foundation | Method for differentiation into retinal cells from stem cells |
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| US6128654A (en) | 1997-02-14 | 2000-10-03 | Advanced Micro Devices, Inc. | Method and apparatus for transmitting multiple copies by replicating data identifiers |
| CN1312807A (zh) | 1998-06-19 | 2001-09-12 | 希龙公司 | 糖元合成酶激酶3的抑制剂 |
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| PT1237880E (pt) | 1999-12-17 | 2008-03-05 | Novartis Vaccines & Diagnostic | Inibidores baseados em pirazina da cinase 3 da glicogénio sintase |
| WO2001044246A1 (en) | 1999-12-17 | 2001-06-21 | Chiron Corporation | Bicyclic inhibitors of glycogen synthase kinase 3 |
| AU2001295026B2 (en) | 2000-09-06 | 2008-04-03 | Novartis Vaccines And Diagnostics, Inc. | Inhibitors of glycogen synthase kinase 3 |
| PL211125B1 (pl) | 2000-09-11 | 2012-04-30 | Novartis Vaccines & Diagnostic | Pochodne chinolinonu jako inhibitory kinazy tyrozynowej, kompozycje je zawierające i ich zastosowanie |
| DE60214703T2 (de) | 2001-06-01 | 2007-09-13 | Vertex Pharmaceuticals Inc., Cambridge | Thiazolverbindungen, die sich als inhibitoren von proteinkinasen eignen |
| RU2004126671A (ru) | 2002-02-06 | 2005-04-10 | Вертекс Фармасьютикалз Инкорпорейтед (Us) | Гетероарилсоединения, полезные в качестве ингибиторов gsk-3 |
| EP1490093A4 (en) | 2002-03-01 | 2007-04-11 | Novartis Vaccines & Diagnostic | METHOD AND COMPOSITIONS FOR TREATING ISCHEMIA |
| US7838290B2 (en) * | 2002-07-25 | 2010-11-23 | The Scripps Research Institute | Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith |
| CN1688573A (zh) | 2002-08-23 | 2005-10-26 | 希龙公司 | 糖原合成酶激酶3的吡咯基抑制剂 |
| CA2502819A1 (en) | 2002-10-21 | 2004-05-06 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| US20050054663A1 (en) | 2003-08-13 | 2005-03-10 | Bennett Christina N. | GSK-3 inhibitors |
| EP1802199A4 (en) * | 2004-09-03 | 2008-08-27 | Scripps Research Inst | HEMATOPOIETIC STEM CELLS OF ISOLATED NEGATIVE LINES AND METHODS OF TREATMENT THEREOF |
| US7850960B2 (en) * | 2004-12-30 | 2010-12-14 | University Of Washington | Methods for regulation of stem cells |
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| US20070231306A1 (en) * | 2005-02-24 | 2007-10-04 | The Scripps Research Institute | Isolated myeloid-like cell populations and methods of treatment therewith |
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-
2011
- 2011-08-05 EP EP11176713A patent/EP2554662A1/en not_active Withdrawn
-
2012
- 2012-08-06 CN CN201280049453.2A patent/CN104011203A/zh active Pending
- 2012-08-06 SG SG2014008080A patent/SG2014008080A/en unknown
- 2012-08-06 RU RU2014108478/10A patent/RU2014108478A/ru not_active Application Discontinuation
- 2012-08-06 JP JP2014523346A patent/JP2014527407A/ja active Pending
- 2012-08-06 EP EP12756386.4A patent/EP2739723A1/en not_active Withdrawn
- 2012-08-06 AR ARP120102872A patent/AR087471A1/es unknown
- 2012-08-06 CA CA2844106A patent/CA2844106A1/en not_active Abandoned
- 2012-08-06 KR KR1020147006060A patent/KR20140068936A/ko not_active Withdrawn
- 2012-08-06 MX MX2014001475A patent/MX2014001475A/es not_active Application Discontinuation
- 2012-08-06 AU AU2012293681A patent/AU2012293681A1/en not_active Abandoned
- 2012-08-06 BR BR112014002718A patent/BR112014002718A8/pt not_active IP Right Cessation
- 2012-08-06 WO PCT/EP2012/065327 patent/WO2013020945A1/en not_active Ceased
- 2012-08-06 US US14/237,297 patent/US20140199277A1/en not_active Abandoned
-
2014
- 2014-02-05 IL IL230830A patent/IL230830A0/en unknown
- 2014-03-05 CO CO14047158A patent/CO7081142A2/es unknown
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050129665A1 (en) * | 2002-07-25 | 2005-06-16 | Martin Friedlander | Isolated lineage negative hematopoietic stem cells and methods of treatment therewith |
| CN1816281A (zh) * | 2003-05-02 | 2006-08-09 | 斯克里普斯研究学院 | 造血干细胞及其治疗新生血管性眼疾的方法 |
| CN101835891A (zh) * | 2007-06-15 | 2010-09-15 | 加内特生物治疗学股份有限公司 | 运用体外培养增殖的自我更新型集落形成细胞治疗疾病和功能紊乱症 |
| EP2090649A1 (en) * | 2008-02-13 | 2009-08-19 | Fondazione Telethon | Method for reprogramming differentiated cells |
| WO2010029288A2 (en) * | 2008-09-11 | 2010-03-18 | Axordia Limited | Growth factor |
| WO2011043591A2 (en) * | 2009-10-06 | 2011-04-14 | Snu R&Db Foundation | Method for differentiation into retinal cells from stem cells |
Non-Patent Citations (3)
| Title |
|---|
| HITOMI AOKI ET AL.: "Embryonic stem cells that differentiate into RPE cell precursors in vitro develop into RPE cell monolayers in vivo", 《EXPERIMENTAL EYE RESEARCH》 * |
| JIN-A KIM ET AL.: "Identification of a Stroma-Mediated Wnt/b-Catenin Signal Promoting Self-Renewal of Hematopoietic Stem Cells in the Stem Cell Niche", 《STEM CELLS》 * |
| TOSHIHIRO INOUE ET AL.: "Activation of Canonical Wnt Pathway Promotes Proliferation of Retinal Stem Cells Derived from Adult Mouse Ciliary Margin", 《STEM CELLS》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108603167A (zh) * | 2015-09-15 | 2018-09-28 | 思特科技公司 | 使用其中引入nanog的源自羊水胎儿的间充质干细胞制备用于促进毛发生长的组合物的方法 |
| CN108603167B (zh) * | 2015-09-15 | 2022-01-21 | 思特科技公司 | 使用nanog引入的源自羊水胎儿的间充质干细胞制备用于促进毛发生长的组合物的方法 |
| CN109414416A (zh) * | 2016-07-07 | 2019-03-01 | 国民大学校产学协力团 | 倍半萜衍生物的新用途 |
| CN109414416B (zh) * | 2016-07-07 | 2021-03-26 | 国民大学校产学协力团 | 倍半萜衍生物的新用途 |
| CN110267972A (zh) * | 2016-11-06 | 2019-09-20 | 纳秒示波器科技有限公司 | 由多特征视蛋白进行的用于视力恢复的光学调制以及其其他应用 |
| CN110706164A (zh) * | 2019-09-03 | 2020-01-17 | 北京爱博同心医学科技有限公司 | 基于增强现实的管状视野图像变形显示方法及眼镜 |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2014108478A (ru) | 2015-09-10 |
| BR112014002718A2 (pt) | 2017-06-13 |
| BR112014002718A8 (pt) | 2017-06-20 |
| AR087471A1 (es) | 2014-03-26 |
| WO2013020945A1 (en) | 2013-02-14 |
| IL230830A0 (en) | 2014-03-31 |
| EP2554662A1 (en) | 2013-02-06 |
| CA2844106A1 (en) | 2013-02-14 |
| CO7081142A2 (es) | 2014-10-10 |
| SG2014008080A (en) | 2014-03-28 |
| KR20140068936A (ko) | 2014-06-09 |
| MX2014001475A (es) | 2014-07-22 |
| JP2014527407A (ja) | 2014-10-16 |
| NZ621345A (en) | 2015-09-25 |
| AU2012293681A1 (en) | 2014-03-06 |
| WO2013020945A9 (en) | 2013-04-04 |
| EP2739723A1 (en) | 2014-06-11 |
| US20140199277A1 (en) | 2014-07-17 |
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