CN104010663B - 含酸式羧甲基纤维素和结晶纤维素的崩解性颗粒组合物及含该组合物的口腔内崩解片剂 - Google Patents

含酸式羧甲基纤维素和结晶纤维素的崩解性颗粒组合物及含该组合物的口腔内崩解片剂 Download PDF

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Publication number
CN104010663B
CN104010663B CN201380004424.9A CN201380004424A CN104010663B CN 104010663 B CN104010663 B CN 104010663B CN 201380004424 A CN201380004424 A CN 201380004424A CN 104010663 B CN104010663 B CN 104010663B
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disintegrating
tablet
crystalline cellulose
granule composition
cellulose
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CN104010663A (zh
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平邑隆弘
以仓圣
石川左枝
冈林智仁
桥川尚弘
森田哲郎
池田君子
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Daicel Corp
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Daicel Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Chemistry (AREA)
CN201380004424.9A 2012-09-20 2013-09-13 含酸式羧甲基纤维素和结晶纤维素的崩解性颗粒组合物及含该组合物的口腔内崩解片剂 Active CN104010663B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012206897 2012-09-20
JP2012-206897 2012-09-20
PCT/JP2013/074823 WO2014046035A1 (ja) 2012-09-20 2013-09-13 酸型カルボキシメチルセルロース及び結晶セルロースを含む崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤

Publications (2)

Publication Number Publication Date
CN104010663A CN104010663A (zh) 2014-08-27
CN104010663B true CN104010663B (zh) 2021-02-19

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Country Link
US (1) US10292934B2 (enExample)
EP (1) EP2898899B1 (enExample)
JP (1) JP6230539B2 (enExample)
KR (1) KR102114487B1 (enExample)
CN (1) CN104010663B (enExample)
IN (1) IN2015DN02907A (enExample)
TW (1) TWI639446B (enExample)
WO (1) WO2014046035A1 (enExample)

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EP2832350B1 (en) 2012-03-29 2019-07-17 Daicel Corporation Method for producing disintegrating particulate composition comprising acid-type carboxymethylcellulose, disintegrating particulate composition comprising acid-type carboxymethylcellulose, and orally disintegrating tablet including disintegrating particulate composition comprising acid-type carboxymethylcellulose
CN105517576A (zh) * 2013-07-06 2016-04-20 株式会社大赛璐 超速崩解片剂及其制备方法
WO2015046223A1 (ja) 2013-09-27 2015-04-02 株式会社ダイセル 二段階の湿式造粒工程で製造される崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤
CN105555262A (zh) * 2013-09-27 2016-05-04 株式会社大赛璐 含有崩解性颗粒组合物的口腔内崩解片剂
JP2017226600A (ja) * 2014-10-16 2017-12-28 株式会社ダイセル 超速崩壊錠剤
CA2968210A1 (en) 2014-11-24 2016-06-02 Daicel Corporation A disintegrative particulate composition comprising milled lactose or granulated lactose
WO2016103904A1 (ja) * 2014-12-25 2016-06-30 株式会社ダイセル 超速崩壊錠剤及びその製造方法
TWI695722B (zh) * 2015-06-29 2020-06-11 日商大賽璐股份有限公司 固態製劑之外層用組成物及含有該外層用組成物之易服用性固態製劑
ES2607715B1 (es) 2015-10-01 2018-01-17 Solutex Na, Lcc Proceso para la preparación y estabilización de emulsiones con omega-3 mediante redes cristalinas isométricas de derivados de celulosa
JP6697874B2 (ja) * 2015-12-25 2020-05-27 日本製紙パピリア株式会社 成形材料及び成形品
EP3406241A4 (en) * 2016-01-18 2019-06-26 Daicel Corporation INTRAORAL RESISTANT DISTILLANT SOLUBLE PREPARATION, METHOD FOR THE MANUFACTURE THEREOF, AND POWDER COMPOSITION USED IN THE SAID MANUFACTURING METHOD
JP2019156723A (ja) * 2018-03-07 2019-09-19 大原薬品工業株式会社 圧縮成形性に優れた賦形剤を用いる、浸透膨潤型口腔内崩壊錠
JP7036856B2 (ja) * 2019-03-28 2022-03-15 日本ケミファ株式会社 口腔内崩壊錠
EP4056638A4 (en) * 2019-11-07 2022-11-30 Asahi Kasei Kabushiki Kaisha COMPOSITION OF CELLULOSE, TABLET AND ORODISPERSIBLE TABLET
ES2976470T3 (es) 2019-11-22 2024-08-01 Noucor Health S A Comprimidos bucodispersables de zonisamida

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JP2000273039A (ja) * 1999-01-20 2000-10-03 Taisho Pharmaceut Co Ltd 口腔内崩壊性組成物
EP1329217A1 (en) * 2000-10-06 2003-07-23 Takeda Chemical Industries, Ltd. Solid preparations
CN102006861A (zh) * 2008-02-13 2011-04-06 大日本住友制药株式会社 口腔崩解片

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US2851453A (en) 1954-08-09 1958-09-09 Smith Kline French Lab Cellulose derivative product, compositions comprising the same and their preparation
JPH10182436A (ja) 1996-10-31 1998-07-07 Takeda Chem Ind Ltd 固形医薬製剤
JP2000290172A (ja) * 1999-04-09 2000-10-17 Earth Chem Corp Ltd 発泡タブレット
JP4284017B2 (ja) 2000-10-06 2009-06-24 武田薬品工業株式会社 固形製剤
JP4551627B2 (ja) 2003-02-28 2010-09-29 東和薬品株式会社 口腔内崩壊錠剤の製造方法
KR20130016386A (ko) 2005-08-10 2013-02-14 시오노기세이야쿠가부시키가이샤 구강내 붕괴 정제
JP5123517B2 (ja) 2005-11-14 2013-01-23 帝人ファーマ株式会社 アンブロキソール口腔内速崩性錠剤
JP5766899B2 (ja) * 2007-04-11 2015-08-19 ニプロ株式会社 口腔内崩壊剤及びその製造方法
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EP2164462B1 (de) 2007-06-06 2017-05-31 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
KR20120046766A (ko) * 2009-08-11 2012-05-10 다이닛본 스미토모 세이야꾸 가부시끼가이샤 2종 이상의 입자들을 함유하는 구강 속붕해성 정제
JP5674666B2 (ja) 2009-08-11 2015-02-25 富士化学工業株式会社 崩壊性粒子組成物及び口腔内速崩壊錠
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JP6073543B2 (ja) 2010-07-08 2017-02-01 沢井製薬株式会社 ロラタジン含有口腔内崩壊錠の製造方法
JP6245677B2 (ja) * 2012-01-20 2017-12-13 ニプロ株式会社 口腔内崩壊錠
EP2832350B1 (en) 2012-03-29 2019-07-17 Daicel Corporation Method for producing disintegrating particulate composition comprising acid-type carboxymethylcellulose, disintegrating particulate composition comprising acid-type carboxymethylcellulose, and orally disintegrating tablet including disintegrating particulate composition comprising acid-type carboxymethylcellulose

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000273039A (ja) * 1999-01-20 2000-10-03 Taisho Pharmaceut Co Ltd 口腔内崩壊性組成物
EP1329217A1 (en) * 2000-10-06 2003-07-23 Takeda Chemical Industries, Ltd. Solid preparations
CN102006861A (zh) * 2008-02-13 2011-04-06 大日本住友制药株式会社 口腔崩解片

Also Published As

Publication number Publication date
JP6230539B2 (ja) 2017-11-15
CN104010663A (zh) 2014-08-27
TWI639446B (zh) 2018-11-01
US20150238424A1 (en) 2015-08-27
TW201417843A (zh) 2014-05-16
WO2014046035A1 (ja) 2014-03-27
KR20150056636A (ko) 2015-05-26
KR102114487B1 (ko) 2020-05-22
JPWO2014046035A1 (ja) 2016-08-18
IN2015DN02907A (enExample) 2015-09-11
US10292934B2 (en) 2019-05-21
EP2898899B1 (en) 2019-09-11
EP2898899A1 (en) 2015-07-29
EP2898899A4 (en) 2016-03-16

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