JP6230539B2 - 酸型カルボキシメチルセルロース及び結晶セルロースを含む崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤 - Google Patents

酸型カルボキシメチルセルロース及び結晶セルロースを含む崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤 Download PDF

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JP6230539B2
JP6230539B2 JP2014536830A JP2014536830A JP6230539B2 JP 6230539 B2 JP6230539 B2 JP 6230539B2 JP 2014536830 A JP2014536830 A JP 2014536830A JP 2014536830 A JP2014536830 A JP 2014536830A JP 6230539 B2 JP6230539 B2 JP 6230539B2
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disintegrating
particle composition
crystalline cellulose
weight
tablet
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JPWO2014046035A1 (ja
Inventor
隆弘 平邑
隆弘 平邑
聖 以倉
聖 以倉
左枝 石川
左枝 石川
智仁 岡林
智仁 岡林
尚弘 橋川
尚弘 橋川
森田　哲郎
哲郎 森田
君子 池田
君子 池田
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Daicel Corp
Nichirin Chemical Industries Ltd
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Daicel Corp
Nichirin Chemical Industries Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Chemistry (AREA)
JP2014536830A 2012-09-20 2013-09-13 酸型カルボキシメチルセルロース及び結晶セルロースを含む崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤 Active JP6230539B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012206897 2012-09-20
JP2012206897 2012-09-20
PCT/JP2013/074823 WO2014046035A1 (ja) 2012-09-20 2013-09-13 酸型カルボキシメチルセルロース及び結晶セルロースを含む崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤

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JPWO2014046035A1 JPWO2014046035A1 (ja) 2016-08-18
JP6230539B2 true JP6230539B2 (ja) 2017-11-15

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US (1) US10292934B2 (enExample)
EP (1) EP2898899B1 (enExample)
JP (1) JP6230539B2 (enExample)
KR (1) KR102114487B1 (enExample)
CN (1) CN104010663B (enExample)
IN (1) IN2015DN02907A (enExample)
TW (1) TWI639446B (enExample)
WO (1) WO2014046035A1 (enExample)

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CN104080443B (zh) 2012-03-29 2017-12-12 株式会社大赛璐 含酸式羧甲基纤维素的崩解性颗粒组合物的制法、及该组合物和含该组合物的口腔崩解片剂
TWI673069B (zh) * 2013-07-06 2019-10-01 日商大賽璐股份有限公司 超高速崩解錠劑及其製造方法
WO2015046223A1 (ja) 2013-09-27 2015-04-02 株式会社ダイセル 二段階の湿式造粒工程で製造される崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤
US20160213619A1 (en) * 2013-09-27 2016-07-28 Daicel Corporation Intraorally disintegrable tablet comprising disintegrable granular composition
JP2017226600A (ja) * 2014-10-16 2017-12-28 株式会社ダイセル 超速崩壊錠剤
CN106999600B (zh) 2014-11-24 2020-11-20 株式会社大赛璐 包含粉碎乳糖或制粒乳糖的崩解性颗粒组合物
WO2016103904A1 (ja) * 2014-12-25 2016-06-30 株式会社ダイセル 超速崩壊錠剤及びその製造方法
TWI695722B (zh) * 2015-06-29 2020-06-11 日商大賽璐股份有限公司 固態製劑之外層用組成物及含有該外層用組成物之易服用性固態製劑
ES2607715B1 (es) 2015-10-01 2018-01-17 Solutex Na, Lcc Proceso para la preparación y estabilización de emulsiones con omega-3 mediante redes cristalinas isométricas de derivados de celulosa
JP6697874B2 (ja) * 2015-12-25 2020-05-27 日本製紙パピリア株式会社 成形材料及び成形品
JP6853191B2 (ja) * 2016-01-18 2021-03-31 株式会社ダイセル 口腔内保持型崩壊性固形製剤、その製造方法、及び該製造方法に用いる粉体組成物
JP2019156723A (ja) * 2018-03-07 2019-09-19 大原薬品工業株式会社 圧縮成形性に優れた賦形剤を用いる、浸透膨潤型口腔内崩壊錠
JP7036856B2 (ja) * 2019-03-28 2022-03-15 日本ケミファ株式会社 口腔内崩壊錠
CA3158393A1 (en) * 2019-11-07 2021-05-14 Asahi Kasei Kabushiki Kaisha Cellulose composition, tablet, and orally disintegrating tablet
EP4061328B1 (en) 2019-11-22 2024-01-03 Biohorm, S.L. Zonisamide orodispersible tablets

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US2851453A (en) 1954-08-09 1958-09-09 Smith Kline French Lab Cellulose derivative product, compositions comprising the same and their preparation
JPH10182436A (ja) 1996-10-31 1998-07-07 Takeda Chem Ind Ltd 固形医薬製剤
JP2000273039A (ja) 1999-01-20 2000-10-03 Taisho Pharmaceut Co Ltd 口腔内崩壊性組成物
JP2000290172A (ja) * 1999-04-09 2000-10-17 Earth Chem Corp Ltd 発泡タブレット
WO2002030400A1 (fr) * 2000-10-06 2002-04-18 Takeda Chemical Industries, Ltd. Preparations solides
JP4284017B2 (ja) * 2000-10-06 2009-06-24 武田薬品工業株式会社 固形製剤
JP4551627B2 (ja) 2003-02-28 2010-09-29 東和薬品株式会社 口腔内崩壊錠剤の製造方法
EP1923074A4 (en) 2005-08-10 2011-09-14 Shionogi & Co TABLET WHICH CAN BE ORALLY DISINTEGRATED
JP5123517B2 (ja) 2005-11-14 2013-01-23 帝人ファーマ株式会社 アンブロキソール口腔内速崩性錠剤
JP5766899B2 (ja) 2007-04-11 2015-08-19 ニプロ株式会社 口腔内崩壊剤及びその製造方法
JP2008285434A (ja) 2007-05-16 2008-11-27 Taisho Pharm Ind Ltd 口腔内速崩壊錠
ES2639130T3 (es) 2007-06-06 2017-10-25 Basf Se Formulación farmacéutica para la fabricación de comprimidos de rápida desintegración
KR101612137B1 (ko) * 2008-02-13 2016-04-12 다이닛본 스미토모 세이야꾸 가부시끼가이샤 구강 내 붕괴정
JP5674666B2 (ja) 2009-08-11 2015-02-25 富士化学工業株式会社 崩壊性粒子組成物及び口腔内速崩壊錠
EP2465495A4 (en) * 2009-08-11 2013-01-23 Dainippon Sumitomo Pharma Co TABLET WITH FAST DECOMPOSITION IN THE MOUTH AND TWO OR MORE TYPES OF PARTICLES
US20110150989A1 (en) 2009-12-22 2011-06-23 Mallinkckrodt Inc. Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans
JP6073543B2 (ja) 2010-07-08 2017-02-01 沢井製薬株式会社 ロラタジン含有口腔内崩壊錠の製造方法
JP6245677B2 (ja) * 2012-01-20 2017-12-13 ニプロ株式会社 口腔内崩壊錠
CN104080443B (zh) 2012-03-29 2017-12-12 株式会社大赛璐 含酸式羧甲基纤维素的崩解性颗粒组合物的制法、及该组合物和含该组合物的口腔崩解片剂

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KR102114487B1 (ko) 2020-05-22
EP2898899B1 (en) 2019-09-11
TWI639446B (zh) 2018-11-01
US20150238424A1 (en) 2015-08-27
CN104010663B (zh) 2021-02-19
CN104010663A (zh) 2014-08-27
KR20150056636A (ko) 2015-05-26
EP2898899A4 (en) 2016-03-16
JPWO2014046035A1 (ja) 2016-08-18
WO2014046035A1 (ja) 2014-03-27
EP2898899A1 (en) 2015-07-29
IN2015DN02907A (enExample) 2015-09-11
US10292934B2 (en) 2019-05-21
TW201417843A (zh) 2014-05-16

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