CN103804522B - 一种提高肝素钠纯度的方法 - Google Patents
一种提高肝素钠纯度的方法 Download PDFInfo
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- CN103804522B CN103804522B CN201310625606.XA CN201310625606A CN103804522B CN 103804522 B CN103804522 B CN 103804522B CN 201310625606 A CN201310625606 A CN 201310625606A CN 103804522 B CN103804522 B CN 103804522B
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
Abstract
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Application Number | Priority Date | Filing Date | Title |
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CN201310625606.XA CN103804522B (zh) | 2013-11-24 | 2013-11-24 | 一种提高肝素钠纯度的方法 |
CN201511002682.0A CN105440164A (zh) | 2013-11-24 | 2013-11-24 | 一种提高肝素钠纯度的方法 |
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CN201310625606.XA CN103804522B (zh) | 2013-11-24 | 2013-11-24 | 一种提高肝素钠纯度的方法 |
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CN201511002682.0A Division CN105440164A (zh) | 2013-11-24 | 2013-11-24 | 一种提高肝素钠纯度的方法 |
Publications (2)
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CN103804522A CN103804522A (zh) | 2014-05-21 |
CN103804522B true CN103804522B (zh) | 2016-09-28 |
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CN201511002682.0A Pending CN105440164A (zh) | 2013-11-24 | 2013-11-24 | 一种提高肝素钠纯度的方法 |
CN201310625606.XA Active CN103804522B (zh) | 2013-11-24 | 2013-11-24 | 一种提高肝素钠纯度的方法 |
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CN201511002682.0A Pending CN105440164A (zh) | 2013-11-24 | 2013-11-24 | 一种提高肝素钠纯度的方法 |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104490793B (zh) * | 2014-11-26 | 2017-08-29 | 山东辰中生物制药有限公司 | 提高肝素钠热稳定性的方法 |
CN104448048A (zh) * | 2014-12-24 | 2015-03-25 | 青岛九龙生物医药有限公司 | 一种提高粗品肝素钠溶解效率的方法 |
CN111939121B (zh) * | 2020-07-13 | 2022-03-08 | 华北制药华坤河北生物技术有限公司 | 一种肝素钠封管注射液及其制备方法 |
CN113831423B (zh) * | 2021-10-20 | 2023-02-03 | 北京赛而生物药业有限公司 | 一种降低肝素钠中硫酸皮肤素含量的方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101575385A (zh) * | 2008-05-09 | 2009-11-11 | 青岛九龙生物医药有限公司 | 萃取法分离肝素钠中的多硫酸软骨素的方法 |
CN101824098A (zh) * | 2010-02-12 | 2010-09-08 | 淮安麦德森化学有限公司 | 快速沉淀分离肝素钠中多硫酸软骨素的方法 |
CN101942040A (zh) * | 2010-09-16 | 2011-01-12 | 山东海科化工集团有限公司 | 肝素钠中多硫酸软骨素的去除方法 |
CN102775523A (zh) * | 2012-07-30 | 2012-11-14 | 南京新百药业有限公司 | 一种制备高纯度低分子肝素钠的工艺 |
CN103030715A (zh) * | 2012-12-07 | 2013-04-10 | 青岛九龙生物医药有限公司 | 一种分离纯化肝素钠的方法 |
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2013
- 2013-11-24 CN CN201511002682.0A patent/CN105440164A/zh active Pending
- 2013-11-24 CN CN201310625606.XA patent/CN103804522B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101575385A (zh) * | 2008-05-09 | 2009-11-11 | 青岛九龙生物医药有限公司 | 萃取法分离肝素钠中的多硫酸软骨素的方法 |
CN101824098A (zh) * | 2010-02-12 | 2010-09-08 | 淮安麦德森化学有限公司 | 快速沉淀分离肝素钠中多硫酸软骨素的方法 |
CN101942040A (zh) * | 2010-09-16 | 2011-01-12 | 山东海科化工集团有限公司 | 肝素钠中多硫酸软骨素的去除方法 |
CN102775523A (zh) * | 2012-07-30 | 2012-11-14 | 南京新百药业有限公司 | 一种制备高纯度低分子肝素钠的工艺 |
CN103030715A (zh) * | 2012-12-07 | 2013-04-10 | 青岛九龙生物医药有限公司 | 一种分离纯化肝素钠的方法 |
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CN105440164A (zh) | 2016-03-30 |
CN103804522A (zh) | 2014-05-21 |
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Inventor after: Zhuang Guihua Inventor after: Liu Naishan Inventor after: Zhou Xiaona Inventor after: Chi Peisheng Inventor after: Xia Chenlai Inventor before: Liu Naishan Inventor before: Zhou Xiaona Inventor before: Chi Peisheng Inventor before: Xia Chenlai |
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Address after: 266100 Zhuzhou Road, Laoshan District, Shandong, No. 97, No. Patentee after: Qingdao Jiulong biological medicine group Co., Ltd. Address before: 266100 Zhuzhou Road, Laoshan District, Shandong, No. 97, No. Patentee before: Qingdao Jiulong Bio-Pharmaceutical Co., Ltd. |