CN103476933B - 白介素1受体的拮抗剂 - Google Patents

白介素1受体的拮抗剂 Download PDF

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CN103476933B
CN103476933B CN201280013172.1A CN201280013172A CN103476933B CN 103476933 B CN103476933 B CN 103476933B CN 201280013172 A CN201280013172 A CN 201280013172A CN 103476933 B CN103476933 B CN 103476933B
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peptide
disease
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peptides
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CN103476933A (zh
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瓦拉迪米·别列津
伊丽莎白·博克
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Frog Co ltd
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Leap Frogg LLC
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CN201280013172.1A 2011-03-14 2012-03-14 白介素1受体的拮抗剂 Expired - Fee Related CN103476933B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201170120 2011-03-14
DKPA201170120 2011-03-14
PCT/DK2012/000022 WO2012122985A1 (en) 2011-03-14 2012-03-14 Antagonists of the interleukin- 1 receptor

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CN103476933A CN103476933A (zh) 2013-12-25
CN103476933B true CN103476933B (zh) 2016-04-13

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US (1) US9359405B2 (enExample)
EP (1) EP2686431B1 (enExample)
JP (1) JP6120782B2 (enExample)
KR (1) KR20140012127A (enExample)
CN (1) CN103476933B (enExample)
AU (1) AU2012228769B2 (enExample)
BR (1) BR112013023309A2 (enExample)
CA (1) CA2828504A1 (enExample)
ES (1) ES2600616T3 (enExample)
MX (1) MX2013010171A (enExample)
RU (1) RU2013145283A (enExample)
WO (1) WO2012122985A1 (enExample)
ZA (1) ZA201306744B (enExample)

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PL2598526T4 (pl) 2010-07-29 2019-05-31 Eleven Biotherapeutics Inc Agoniści i antagoniści receptora typu i chimerycznej interleukiny il-1
KR102017026B1 (ko) * 2013-01-10 2019-09-02 (주) 수파드엘릭사 염증 또는 알러지의 예방 또는 치료용 약학 조성물 및 염증 또는 알러지 개선용 화장료 조성물
CN107693781B (zh) 2013-03-13 2021-11-09 巴扎德制药公司 用于眼部递送的嵌合细胞因子制剂
JP2016520615A (ja) * 2013-05-31 2016-07-14 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． アルツハイマー病を処置するためのｉｌ−１アンタゴニストを使用する方法
CN104711214B (zh) * 2015-04-09 2019-02-12 武汉联程生物科技有限公司 一种大肠杆菌bbm2015001菌株及其用途
WO2017063657A1 (en) 2015-10-14 2017-04-20 Phlogo Aps Il1ra-derived peptide antagonist
CN110382001A (zh) * 2017-02-16 2019-10-25 埃克斯生物科技公司 化脓性汗腺炎的治疗
US12216128B2 (en) 2018-04-12 2025-02-04 Mayo Foundation For Medical Education And Research Methods for guiding therapy decisions in seizure disorders
KR102022118B1 (ko) * 2019-01-07 2019-09-18 주식회사 아스트로젠 중추신경계 질환의 예방 또는 치료용 세린 유도체 화합물
ES3026437T3 (en) * 2021-07-13 2025-06-11 Serodus Aps Il1ra derived peptides for treatment of diabetic nephropathy
CN114177295B (zh) * 2021-12-16 2023-09-19 上海市第五人民医院 白细胞介素1受体拮抗剂治疗非酒精性脂肪性肝病的应用
CN116144668A (zh) * 2023-02-13 2023-05-23 杭州吉倍思生物制药有限公司 人il-1r1基因、蛋白、同源二聚体蛋白质与用途
AU2024255810A1 (en) * 2023-04-14 2025-11-13 Merck Sharp & Dohme Llc A cyclic peptide for trapping interleukin-1 beta
WO2025101453A1 (en) * 2023-11-07 2025-05-15 University Of Washington De novo design of potent minibinder antagonists of il-6r, gp130, and il1-r1

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