CN103463225A - Traditional Chinese medicine micro-ecologic preparation for preventing and treating newcastle disease and preparation method thereof - Google Patents
Traditional Chinese medicine micro-ecologic preparation for preventing and treating newcastle disease and preparation method thereof Download PDFInfo
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- CN103463225A CN103463225A CN2013104339617A CN201310433961A CN103463225A CN 103463225 A CN103463225 A CN 103463225A CN 2013104339617 A CN2013104339617 A CN 2013104339617A CN 201310433961 A CN201310433961 A CN 201310433961A CN 103463225 A CN103463225 A CN 103463225A
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Abstract
The invention relates to a traditional Chinese medicine micro-ecologic preparation for preventing and treating a newcastle disease and a preparation method thereof. The traditional Chinese medicine micro-ecologic preparation is prepared by the following steps of adding water and boiling honeysuckle, fructus forsythia, isatis root, herba kalimeridis, dandelion, coptis chinensis, astragalus membranaceus, angelica sinensis and liquorice with strong fire, keeping warm for 30-60 minutes with soft fire, cooling and filtering, collecting the filtrate, adding white sugar and boiling, cooling to normal temperature, then inoculating lactobacillus, bayer jointed saccharomycetes and acetobacter xylinum, and fermenting for 3-7 days, thereby obtaining the micro-ecologic preparation. After being diluted according to the proportion, the micro-ecologic preparation can be directly taken by chickens. The traditional Chinese medicine micro-ecologic preparation has effects of resisting virus, inducing interferon, increasing the quantity of effective microbial communities in intestinal canals, improving the immunity, improving the resistance to diseases of chickens, and having no toxic and side effects. The preparation method is simple and convenient to use, has no residue, and can produce the traditional Chinese medicine micro-ecologic preparation with high content of viable organism. The content of the effective components of the fermented traditional Chinese medicine is increased by multiples. The traditional Chinese medicine micro-ecologic preparation has a good market prospect.
Description
Technical field
The invention belongs to veterinary drug microbial ecological agent technical field, relate to specifically a kind of Chinese medicine microecological preparation and preparation method for natural green fowl of preventing and treating newcastle disease.This Chinese medicine microecological preparation has obvious inhibitory or killing effect to Avian pneumo-encephalitis virus, increases beneficial microbe colony quantity in intestinal, improves body's immunity, the enhancing body resistance against diseases.
Background technology
Newcastle also claims philippine fowl disease, is commonly called as fowl plague, is the chicken that caused by Avian pneumo-encephalitis virus and the acute height contagious disease of turkey, often is the deteriorated blood process.Principal character is that dyspnea, dysentery, nervous function disorder and serous coat and mucosa are significantly hemorrhage, by World Health Organization (WHO) (0IE), is classified as the category-A infectious disease.This disease since China is found, has become rapidly China's poultry husbandry harm maximum, has caused one of fowl diseases that economic loss is the most serious before and after nineteen twenty-eight, and the annual economic loss caused due to this disease reaches billions of units.
Main employing vaccination at present prevents the generation of this disease, basic controlling typicality newcastle popular, but the factors such as interference that virus variation, vaccine use and improper storage, malnutrition, other diseases antagonist produce all can cause immuning failure, cause atypical newcastle often to occur.If, to the antiviral amantadine of drug main and the ribavirin of Newcastle Disease treatment, zoopery shows that two kinds of medicines all have teratogenesis, but and the also generation of inducible resistance strain of amantadine, prolonged application develops immunity to drugs virus to affect the treatment.
Although herbal medicine preparation SHUANGHUANLIAN, astragalus polysaccharides, Radix Isatidis, QINGKAILING etc. have become one of main method of veterinary clinic treatment poultry antiviral property disease, in the clinical epidemic prevention of epidemic disease, play an important role, but these medicines do not show gratifying clinical effectiveness to many clinical common virosiss, therefore, continue the effective clinical application of research and development one of the person's main task that remains the veterinary work.
There is the problem of the following aspects in microbial ecological agent on market: viable bacteria content is low; Antibiotic-resistant not; Unstable to high temperature, gastric acid and cholate; The problems such as storage life is short, thus the extensive use of microbial ecological agent affected.
And the Chinese medicine microecological preparation of preparation that Chinese medicine is fermented together with microorganism has no report in prior art.
Summary of the invention
The purpose of this invention is to provide a kind of the have newcastle disease of control disease Chinese medicine microecological preparation and preparation method, simple, the easy to use, safe environmental protection of this preparation method, pure ecology, pollution-free, noresidue, viable bacteria content are high, and the content of Effective Component of Chinese Medicine can be multiplied.
For achieving the above object, the method that the present invention adopts is as follows:
A kind of Chinese medicine microecological preparation and preparation method of preventing and treating newcastle disease is characterized in that: it is the Chinese medicine composition by following weight portion: Flos Lonicerae 60～80, Fructus Forsythiae 60～80, Radix Isatidis 60～80, Herba Kalimeridis grass 40～60, Herba Taraxaci 40～60, Rhizoma Coptidis 40～60, the Radix Astragali 30～40, Radix Angelicae Sinensis 30～40, Radix Glycyrrhizae 20～30.
Described a kind of Chinese medicine microecological preparation and preparation method of preventing and treating newcastle disease, it is characterized in that each Chinese herbal medicine is pulverized, take the Chinese herbal medicine of weight portion, the water that adds 6～8 times of amounts of Chinese herbal medicine gross weight, soak 30～60min, intense fire boils, slow fire insulation 30～60min, cooling Floor 12 filtered through gauze; Filtering residue adds the water of 4～5 times of amounts again, and intense fire boils, slow fire insulation 30～60min, and cooling Floor 12 filtered through gauze, merge filtrate twice.
Described a kind of Chinese medicine microecological preparation and preparation method of preventing and treating newcastle disease, it is characterized in that take that 100Kg filtrate is as the interpolation white sugar 15～20Kg of unit, and boil 5～10min, be cooled to room temperature, inoculating lactobacillus, acetobacter xylinum, Bayer combining yeast bacteria preparation 10～15Kg, fermentation is to till growing white truffle.
Described a kind of Chinese medicine microecological preparation and preparation method of preventing and treating newcastle disease, it is characterized in that white sugar also can replace with Mel, crystal sugar or glucose: when with Mel, consumption is 20～25Kg; During with crystal sugar, consumption is 20～25Kg; During with glucose, consumption is 21～28Kg.
Described a kind of Chinese medicine microecological preparation and preparation method of preventing and treating newcastle disease, is characterized in that, preparation process is as follows:
(1) take the Chinese herbal medicine of weight portion; Flos Lonicerae 60～80, Fructus Forsythiae 60～80, Radix Isatidis 60～80, Herba Kalimeridis grass 40～60, Herba Taraxaci 40～60, Rhizoma Coptidis 40～60, the Radix Astragali 30～40, Radix Angelicae Sinensis 30～40, Radix Glycyrrhizae 20～30.
(2) Chinese herbal medicine is pulverized, added the water of 6～8 times of amounts of Chinese medicine gross weight, soak, intense fire boils, slow fire insulation 30～60min, cooling Floor 12 layer filtered through gauze; Filtering residue adds the water of 4～5 times of amounts again, and intense fire boils, slow fire insulation 30～60min, and cooling Floor 12 filtered through gauze, merge filtrate twice.
(3) in filtrate, add white sugar, lactobacillus, the fermentation of acetobacter xylinum Bayer zygosaccharomyces bacterium to till growing white truffle.
A kind of described Chinese medicine microecological preparation and preparation method method of preventing and treating newcastle disease, is characterized in that the fermentation in step (3) is to carry out in aseptic fermenting cellar.
A kind of described Chinese medicine microecological preparation and preparation method method of preventing and treating newcastle disease, is characterized in that fermentation time is about 3～7 days, and fermentation temperature is 33～37 ℃.
A kind of described Chinese medicine microecological preparation and preparation method method of preventing and treating newcastle disease is characterized in that the gained fermentation liquid dilutes 5～15 times and directly drinks to chicken afterwards:
During the prevention newcastle disease, by 10～15 times of fermentation liquid dilutions, to chicken, drink 7 days continuously;
During the treatment newcastle disease, by 5～10 times of fermentation liquid dilutions, to chicken, drink 7 days continuously.
The thering is profitable strain quantity in antiviral, inducement interferon, increase intestinal, improve immunologic function, strengthen chicken body premunition of Chinese medicine microecological preparation of the present invention, the effect such as without any side effects.
The specific embodiment
Embodiment 1
A kind of Chinese medicine microecological preparation and preparation method of preventing and treating newcastle disease comprises the following steps:
Take following weight (Kg) Chinese herbal medicine: Flos Lonicerae 60, Fructus Forsythiae 60, Radix Isatidis 60, Herba Kalimeridis grass 40, Herba Taraxaci 40, Rhizoma Coptidis 40, the Radix Astragali 30, Radix Angelicae Sinensis 30, Radix Glycyrrhizae 20.
The preparation of fermentation liquid: add the water of 6～8 times of amounts of Chinese herbal medicine gross weight, soak 30～60min, intense fire boils, slow fire insulation 30～60min, cooling Floor 12 filtered through gauze; Filtering residue adds the water of 4～5 times of amounts again, and intense fire boils, slow fire insulation 30～60min, and cooling Floor 12 filtered through gauze, merge filtrate twice.100Kg filtrate is that unit adds white sugar 20～25Kg, and boils 5～10min, is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum, Bayer combining yeast bacteria preparation 5～10Kg, and fermentation is to carry out in aseptic fermenting cellar.Fermentation is to till growing white truffle.
The gained fermentation liquid dilutes 5～15 times and directly drinks to goose afterwards: during the prevention newcastle disease, by 10～15 times of fermentation liquid dilutions, to chicken, drink 7 days continuously; During the treatment newcastle disease, by 5～10 times of fermentation liquid dilutions, to chicken, drink 7 days continuously.
Embodiment 2
Take following weight (Kg) Chinese herbal medicine: Flos Lonicerae 80, Fructus Forsythiae 80, Radix Isatidis 80, Herba Kalimeridis grass 60, Herba Taraxaci 60, Rhizoma Coptidis 60, the Radix Astragali 40, Radix Angelicae Sinensis 40, Radix Glycyrrhizae 30.All the other processing steps etc. are all with example 1.
Claims (8)
1. Chinese medicine microecological preparation and a preparation method of preventing and treating newcastle disease is characterized in that: it is that Chinese medicine by following weight portion forms: Flos Lonicerae 60～80, Fructus Forsythiae 60～80, Radix Isatidis 60～80, Herba Kalimeridis grass 40～60, Herba Taraxaci 40～60, Rhizoma Coptidis 40～60, the Radix Astragali 30～40, Radix Angelicae Sinensis 30～40, Radix Glycyrrhizae 20～30.
2. a kind of Chinese medicine microecological preparation and preparation method of preventing and treating newcastle disease according to claim 1, it is characterized in that each Chinese herbal medicine is pulverized, take the Chinese herbal medicine of weight portion, the water that adds 6～8 times of amounts of Chinese herbal medicine gross weight, soak 30～60min, intense fire boils, slow fire insulation 30～60min, cooling Floor 12 filtered through gauze; Filtering residue adds the water of 4～5 times of amounts again, and intense fire boils, slow fire insulation 30～60min, and cooling Floor 12 filtered through gauze, merge filtrate twice.
3. according to claim 1,2 described a kind of Chinese medicine microecological preparation and preparation methoies of preventing and treating newcastle disease, it is characterized in that take that 100Kg filtrate is as the interpolation white sugar 15～20Kg of unit, and boil 5～10min, be cooled to room temperature, inoculating lactobacillus, acetobacter xylinum, Bayer combining yeast bacteria preparation 10～15Kg, fermentation is to till growing white truffle.
4. a kind of Chinese medicine microecological preparation and preparation method of preventing and treating newcastle disease according to claim 3, it is characterized in that white sugar also can replace with Mel, crystal sugar or glucose: when with Mel, consumption is 20～25Kg; During with crystal sugar, consumption is 20～25Kg; During with glucose, consumption is 21～28Kg.
5. according to claim 1,2,3 described a kind of Chinese medicine microecological preparation and preparation methoies of preventing and treating newcastle disease, it is characterized in that, preparation process is as follows:
(1) take the Chinese herbal medicine of weight portion;
(2) Chinese herbal medicine is pulverized, added the water of 6～8 times of amounts of Chinese medicine gross weight, soak, intense fire boils, slow fire insulation 30～60min, cooling Floor 12 layer filtered through gauze; Filtering residue adds the water of 4～5 times of amounts again, and intense fire boils, slow fire insulation 30～60min, and cooling Floor 12 filtered through gauze, merge filtrate twice.
(3) in filtrate, add white sugar, lactobacillus, the fermentation of acetobacter xylinum Bayer zygosaccharomyces bacterium to till growing white truffle.
6. a kind of Chinese medicine microecological preparation and preparation method method of preventing and treating newcastle disease according to claim 5, is characterized in that the fermentation in step (3) is to carry out in aseptic fermenting cellar.
7. according to claim 5,6 a kind of described Chinese medicine microecological preparation and preparation method methods of preventing and treating newcastle disease, it is characterized in that fermentation time is about 3～7 days, fermentation temperature is 33～37 ℃.
8. according to claim 5,6,7 a kind of described Chinese medicine microecological preparation and preparation method methods of preventing and treating newcastle disease, it is characterized in that the gained fermentation liquid dilutes 5～15 times and directly drinks to chicken afterwards:
During the prevention newcastle disease, by 10～15 times of fermentation liquid dilutions, to chicken, drink 7 days continuously;
During the treatment newcastle disease, by 5～10 times of fermentation liquid dilutions, to chicken, drink 7 days continuously.
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Cited By (7)
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| CN103859168A (en) * | 2014-04-03 | 2014-06-18 | 常熟理工学院 | Avian influenza resistant feed additive for large-scale ecological chicken breeding and preparation and use methods thereof |
| CN103918723A (en) * | 2014-04-18 | 2014-07-16 | 安徽省淮北市农药厂 | Method for preparing biological agent by radix euphorbiae ebracteolatae |
| CN104397348A (en) * | 2014-12-26 | 2015-03-11 | 郭庆 | Preparation method of new castle disease traditional Chinese medicine feed additive |
| CN104431460A (en) * | 2014-11-20 | 2015-03-25 | 惠州市欧野科技有限公司 | Biological feed |
| CN105831391A (en) * | 2015-01-16 | 2016-08-10 | 北京大北农动物保健科技有限责任公司 | Chinese medicinal micro-ecological granule for control of newcastle disease, feed and application thereof |
| CN107787916A (en) * | 2017-10-28 | 2018-03-13 | 蚌埠宏瑞园林有限公司 | A kind of cultural method for preventing duckling infectious serositis |
| CN115708855A (en) * | 2022-10-13 | 2023-02-24 | 安徽中科爱生生物工程有限公司 | Microbial fermentation traditional Chinese medicine preparation for resisting newcastle disease and preparation method thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103859168A (en) * | 2014-04-03 | 2014-06-18 | 常熟理工学院 | Avian influenza resistant feed additive for large-scale ecological chicken breeding and preparation and use methods thereof |
| CN103918723A (en) * | 2014-04-18 | 2014-07-16 | 安徽省淮北市农药厂 | Method for preparing biological agent by radix euphorbiae ebracteolatae |
| CN104431460A (en) * | 2014-11-20 | 2015-03-25 | 惠州市欧野科技有限公司 | Biological feed |
| CN104397348A (en) * | 2014-12-26 | 2015-03-11 | 郭庆 | Preparation method of new castle disease traditional Chinese medicine feed additive |
| CN105831391A (en) * | 2015-01-16 | 2016-08-10 | 北京大北农动物保健科技有限责任公司 | Chinese medicinal micro-ecological granule for control of newcastle disease, feed and application thereof |
| CN105831391B (en) * | 2015-01-16 | 2021-02-09 | 北京大北农动物保健科技有限责任公司 | Traditional Chinese medicine micro-ecological granules for preventing and treating newcastle disease, feed and application thereof |
| CN107787916A (en) * | 2017-10-28 | 2018-03-13 | 蚌埠宏瑞园林有限公司 | A kind of cultural method for preventing duckling infectious serositis |
| CN115708855A (en) * | 2022-10-13 | 2023-02-24 | 安徽中科爱生生物工程有限公司 | Microbial fermentation traditional Chinese medicine preparation for resisting newcastle disease and preparation method thereof |
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Application publication date: 20131225 |