CN104068286B - A kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis - Google Patents
A kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis Download PDFInfo
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Abstract
A kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis, it is prepared by the following method, by Radix Isatidis, Hypericum Chinense, cape jasmine, macleaya cordata, mother chrysanthemum, Chinese lobelia, the Chinese bulbul, plantain seed, the Radix Astragali, Radix Angelicae Sinensis, the Radix Glycyrrhizae intense fire that adds water boils, slow fire insulation 30 ~ 60min, cold filtration, collect filtrate, add white sugar to boil, bacillus subtilis is inoculated after normal temperature is down in cooling, Bacillus acidi lactici and Bayer Zygosaccharomyces bacterium are through 3 ~ 7d fermentation gained microbial forage additive, drink directly to duck after gained microbial forage additive dilutes in proportion.Having of Chinese herbal feed additive of the present invention is antiviral, profitable strain quantity in inducement interferon, increase enteron aisle, improve immunologic function, strengthen duck body premunition, the effect such as without any side effects, and preparation method is simple, easy to use, noresidue, viable bacteria content are high.The needs that applicable large-scale industrial of the present invention is produced, have good market prospects.
Description
Technical field
The invention belongs to field of feed additive technology, relate to a kind of preparation method preventing and treating the Traditional Chinese drug microecology feed addictive of duck virus hepatitis specifically.
Background technology
Duck virus hepatitis (Duckviralhepatitis, DVH) be by DHV (Duckhepatitisvirus, DHV) the acute hyperinfection disease of the one caused, duckling within 3 week age of main infringement, finds this disease in U.S. first in 1945, and called after I type duck virus hepatitis, nineteen sixty-five has found duck virus hepatitis II type in Britain, within 1969, found duck virus hepatitis type III in the U.S., at present, I type is worldwide distribution.The feature of this disease is sudden onset, and propagate fast, the course of disease is short, and the death rate is high, sudden onset, down in spirits, drop-head hogback, subtracts food and does not eat, nonvoluntary activity, and eye closing is dozed off, and contacts to earth with head, occurs diarrhoea, and sick duck is uneasy subsequently, occurs nervous symptoms.Clinical anatomic is characterized as: the visible liver enlargement of major lesions, and quality is soft, embrittlement, and outward appearance pinkiness or khaki sex change, there are needle point sample size darkviolet blutpunkte or sheet blood cake in surface, gollbladder dilation.
At present, mainly vaccine prevention is used to duck virus hepatitis (DHV), duck hepatitis B virus infection, basic controlling typicalness duck virus hepatitis popular.Immunity vaccine often causes immuning failure because of preservation and improper use, and some area causes popular because immune density is not high, and provisions duck industry causes serious economic loss.After the morbidity of this disease, do not have good medicine at present, although Yolk antibody, high immune serum, mab treatment have good effect to this disease, due to expensive, the factors such as the source of goods is in short supply cause practical application less.
One of main method of having become veterinary clinic treatment livestock and poultry antiviral property disease although herbal medicine swap buffers, astragalus polyose, Qing kailing, fowl health fall apart etc., play an important role in the clinical epidemic prevention of epidemic disease, many achievements in research all confirm that treatment by Chinese herbs duck virus hepatitis is feasible, therefore, need to develop the Chinese medicine preparation that can substitute Yolk antibody, high immune serum, monoclonal antibody, and promoted the use of.Therefore, continue the effective clinical application of research and development and remain one of veterinarian's main task.
And by Chinese herbal feed additive standby for Chinese medicine fermentation together with microorganism, in prior art, have no report.
Summary of the invention
Technical problem to be solved by this invention be to provide a kind of treat duck virus hepatitis effective, serum antibody titer can be improved, virus function is had to many targets, the preparation method of low-residual, biological safety are good, easy to use Chinese herbal feed additive, simple, the easy to use, safe environmental protection of this preparation method, pure ecology, pollution-free, noresidue, viable bacteria content are high.
For achieving the above object, the method that the present invention adopts is as follows:
A kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis, it is characterized in that: it is prepared by the following method, by Radix Isatidis, Hypericum Chinense, cape jasmine, macleaya cordata, mother chrysanthemum, Chinese lobelia, the Chinese bulbul, plantain seed, the Radix Astragali, Radix Angelicae Sinensis, the Radix Glycyrrhizae intense fire that adds water boils, slow fire insulation 30 ~ 60min, cold filtration, collect filtrate, add white sugar to boil, bacillus subtilis is inoculated after normal temperature is down in cooling, Bacillus acidi lactici and Bayer Zygosaccharomyces bacterium are through 3 ~ 7d fermentation gained microbial forage additive, drink directly to duck after gained microbial forage additive dilutes in proportion.
Described a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis, is characterized in that: the Chinese medicine composition taking following weight portion: Radix Isatidis 80 ~ 100, Hypericum Chinense 80 ~ 100, cape jasmine 60 ~ 80, macleaya cordata 60 ~ 80, mother chrysanthemum 60 ~ 80, Chinese lobelia 50 ~ 70, the Chinese bulbul 50 ~ 70, plantain seed 40 ~ 60, the Radix Astragali 40 ~ 60, Radix Angelicae Sinensis 30 ~ 40, Radix Glycyrrhizae 20 ~ 30.
Described a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis, it is characterized in that: each Chinese herbal medicine is pulverized, take the Chinese herbal medicine of weight portion, add the water of Chinese herbal medicine gross weight 6 ~ 8 times amount, soak 30 ~ 60min, intense fire boils, slow fire insulation 30 ~ 60min, cooling Floor 12 filtered through gauze; Filter residue adds the water of 4 ~ 5 times amount again, and intense fire boils, slow fire insulation 30 ~ 60min, and cooling Floor 12 filtered through gauze, merges twice filtrate.
Described a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis, it is characterized in that: in units of 100Kg filtrate, add white sugar 15 ~ 20Kg, and boil 5 ~ 10min, be cooled to normal temperature, inoculation bacillus subtilis, Bacillus acidi lactici and Bayer combining yeast bacteria preparation 10 ~ 15Kg, ferment to pH6.0 ~ 6.5.
Described a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis, it is characterized in that substituting white sugar with honey, rock sugar, glucose, honey consumption is 20 ~ 25Kg; Rock sugar consumption is 10 ~ 15Kg; Glucose consumption is 21 ~ 25Kg.
Described a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis, is characterized in that: fermentation carries out in aseptic fermenting cellar.
Described a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis, is characterized in that: fermentation time is about 3 ~ 7 days, and fermentation temperature is 33 ~ 37 DEG C.
Described a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis, is characterized in that: drink directly to duck after gained zymotic fluid dilution 3 ~ 8 times:
During preventing duck virus hepatitis, by zymotic fluid dilution 5 ~ 8 times, drink 7 days to duck continuously;
During treatment duck virus hepatitis, by zymotic fluid dilution 3 ~ 5 times, drink 7 days to duck continuously.
Having of Chinese herbal feed additive of the present invention is antiviral, profitable strain quantity in inducement interferon, increase enteron aisle, improve immunologic function, strengthen duck body premunition, the effect such as without any side effects.
Detailed description of the invention
embodiment 1
Prevent and treat a preparation method for the Chinese herbal feed additive of duck virus hepatitis, comprise the following steps:
Take following weight (Kg) Chinese herbal medicine: Radix Isatidis 80, Hypericum Chinense 80, cape jasmine 60, macleaya cordata 60, mother chrysanthemum 60, Chinese lobelia 50, the Chinese bulbul 50, plantain seed 40, the Radix Astragali 40, Radix Angelicae Sinensis 30, Radix Glycyrrhizae 20.
The preparation of zymotic fluid: the water adding Chinese herbal medicine gross weight 6 times amount, soak 30min, intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze; Filter residue adds the water of 4 times amount again, and intense fire boils, slow fire insulation 30min, and cooling Floor 12 filtered through gauze, merges twice filtrate.100Kg filtrate is that unit adds white sugar 20Kg, and boils 5min, is cooled to normal temperature, and inoculation bacillus subtilis, Bacillus acidi lactici and Bayer combining yeast bacteria preparation 5Kg, fermentation carries out in aseptic fermenting cellar.Fermentation is to pH6.0.
Drink directly to duck after gained zymotic fluid dilution 3 ~ 8 times: during preventing duck virus hepatitis, by zymotic fluid dilution 5 ~ 8 times, drink 7 days to duck continuously.
embodiment 2
Prevent and treat a preparation method for the Chinese herbal feed additive of duck virus hepatitis, comprise the following steps:
Take following weight (Kg) Chinese herbal medicine: Radix Isatidis 100, Hypericum Chinense 100, cape jasmine 80, macleaya cordata 80, mother chrysanthemum 80, Chinese lobelia 70, the Chinese bulbul 70, plantain seed 60, the Radix Astragali 60, Radix Angelicae Sinensis 40, Radix Glycyrrhizae 30.
The preparation of zymotic fluid: the water adding Chinese herbal medicine gross weight 8 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze; Filter residue adds the water of 5 times amount again, and intense fire boils, slow fire insulation 60min, and cooling Floor 12 filtered through gauze, merges twice filtrate.100Kg filtrate is that unit adds white sugar 25Kg, and boils 5 ~ 10min, is cooled to normal temperature, and inoculation bacillus subtilis, Bacillus acidi lactici and Bayer combining yeast bacteria preparation 10Kg, fermentation carries out in aseptic fermenting cellar.Fermentation is to pH6.5.
Drink directly to duck after gained zymotic fluid dilution 3 ~ 8 times: during treatment duck virus hepatitis, by zymotic fluid dilution 3 ~ 5 times, drink 7 days to duck continuously.
Claims (6)
1. prevent and treat the preparation method of the Chinese herbal feed additive of duck virus hepatitis for one kind, it is characterized in that: it is made by the Chinese medicine of following weight portion, Radix Isatidis 80 ~ 100, Hypericum Chinense 80 ~ 100, cape jasmine 60 ~ 80, macleaya cordata 60 ~ 80, mother chrysanthemum 60 ~ 80, Chinese lobelia 50 ~ 70, the Chinese bulbul 50 ~ 70, plantain seed 40 ~ 60, the Radix Astragali 40 ~ 60, Radix Angelicae Sinensis 30 ~ 40, Radix Glycyrrhizae 20 ~ 30; Each Chinese medicine is pulverized, takes the Chinese medicine of above-mentioned weight portion, add the water of Chinese medicine gross weight 6 ~ 8 times amount, soak 30 ~ 60min, intense fire boils, slow fire insulation 30 ~ 60min, cooling Floor 12 filtered through gauze, filter residue adds the water of 4 ~ 5 times amount again, intense fire boils, slow fire insulation 30 ~ 60min, cooling Floor 12 filtered through gauze, merge twice filtrate, add white sugar and boil; Bacillus subtilis, Bacillus acidi lactici and Bayer Zygosaccharomyces bacterium is inoculated through 3 ~ 7 days fermentation gained microbial forage additives after normal temperature is down in cooling; Drink directly to duck after gained microbial forage additive dilutes in proportion.
2. a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis according to claim 1, it is characterized in that: in units of 100Kg filtrate, add white sugar 15 ~ 20Kg, and boil 5 ~ 10min, be cooled to normal temperature, inoculation bacillus subtilis, Bacillus acidi lactici and Bayer Zygosaccharomyces bacteria preparation 10 ~ 15Kg, ferment to pH6.0 ~ 6.5.
3. a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis according to claim 1, it is characterized in that substituting white sugar with honey, rock sugar, glucose, honey consumption is 20 ~ 25Kg; Rock sugar consumption is 10 ~ 15Kg; Glucose consumption is 21 ~ 25Kg.
4. a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis according to claim 1, is characterized in that: fermentation carries out in aseptic fermenting cellar.
5. a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis according to claim 1, it is characterized in that: fermentation time is 3 ~ 7 days, fermentation temperature is 33 ~ 37 DEG C.
6. a kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis according to claim 1, is characterized in that: during preventing duck virus hepatitis, by zymotic fluid dilution 5 ~ 8 times, drinks 7 days continuously to duck; During treatment duck virus hepatitis, by zymotic fluid dilution 3 ~ 5 times, drink 7 days to duck continuously.
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| CN105166465B (en) * | 2015-08-13 | 2018-11-27 | 宿迁益客种禽有限公司 | The feed addictive and its preparation method and application for preventing and treating duck hepatitis disease |
| CN107873987A (en) * | 2017-11-22 | 2018-04-06 | 漳州傲农牧业科技有限公司 | A kind of feed addictive for improving the gentle solution transport stress of fattening pig immunity and preparation method and application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1559532A (en) * | 2004-02-23 | 2005-01-05 | 高和平 | Chinese medicinal mixture for treating viral hepatitis |
| CN102960306A (en) * | 2012-11-29 | 2013-03-13 | 郭庆 | Method for producing Chinese herbal medicine Muscovy duck |
| CN102972342A (en) * | 2012-11-29 | 2013-03-20 | 郭庆 | Production method of Chinese herbal health-care duck eggs |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1559532A (en) * | 2004-02-23 | 2005-01-05 | 高和平 | Chinese medicinal mixture for treating viral hepatitis |
| CN102960306A (en) * | 2012-11-29 | 2013-03-13 | 郭庆 | Method for producing Chinese herbal medicine Muscovy duck |
| CN102972342A (en) * | 2012-11-29 | 2013-03-20 | 郭庆 | Production method of Chinese herbal health-care duck eggs |
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Effective date of registration: 20160714 Address after: 510850, Guangzhou, Guangdong province Huadu District charcoal step Industrial Park Patentee after: Guangzhou Yi Shengbao animal pharmaceutical estate Co., Ltd Address before: 235000 Anhui city of Huaibei Province Meng Xiangshan District Road No. 59 building 503 room 1 Patentee before: Guo Qing |