CN103315932B - Itching-relieving body wash and preparation method thereof - Google Patents
Itching-relieving body wash and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an itching-relieving body wash and a preparation method thereof. The itching-relieving body wash comprises the raw materials of, by mass, 1.0-20.0% of an amphoteric surfactant, 6.0-20.0% of an anionic surfactant, 0.5-8.0% of a non-ionic surfactant, 0.1-8.0% of a polyol humectant, 0.5-2.0% of a traditional Chinese medicine extract, 0.1-2.0% of a moisture, 0.01-2.0% of phytosterol, 0.01-0.5% of a chelating agent, 0-2.0% of a pearlescent agent, 0-2.0% of a viscosity adjusting agent, 0-0.5% of a conditioning agent, 0-0.5% of a foam stabilizing agent, 0-0.5% of an essence, 0-0.2% of a pH adjusting agent, 0-0.8% of a preservative, and balance of deionized water. The traditional Chinese medicine extract comprises a mixture of a purslane extract and a common cnidium fruit extract. The itching-relieving body wash has excellent antihistamine, antibacterial, bacteria-inhibiting, anti-inflammatory, and anti-allergic effects.
Description
Technical field
The present invention relates to a kind of itching-relieving shower reveals and preparation method thereof.
Background technology
Along with social development and the raising of living standards of the people, consumer is also more and more higher to the requirement of daily nursing product, and effect of product is required to also more and more refinement.In this case, only have the bath gel of cleaning function to be just difficult to satisfy the demands of consumers.In recent years, have the bath gel of itching-relieving action also to occur successively, but antipruritic effect is not fine, bath gel the inside composition is difficult to bring into play its effect.
Summary of the invention
Technical problem to be solved by this invention is to have overcome in prior art that bath gel function is limited, antipruritic effect is not fine, bath gel the inside composition is difficult to bring into play the defect of its effect, provide a kind of antipruritic effect good, composition play a role itching-relieving shower reveal.
The invention provides a kind of itching-relieving shower and reveal, by mass percentage, it contains following raw material components:
Amphoteric surfactant 1.0～20.0%, anion surfactant 6.0～20.0%, non-ionic surface active agent 0.5～8.0%, polyhydric alcohol wetting agent 0.1～8.0%, Chinese medicine ingredients extract 0.5～2.0%, moisturizing agent 0.1～2.0%, plant sterol 0.01～2.0%, chelating agen 0.01～0.5%, pearling agent 0～2.0%, viscosity modifier 0～2.0%, conditioner 0～0.5%, foam stabilizer 0～0.5%, essence 0～0.5%, acid-base modifier 0～0.2%, antiseptic 0～0.8%, deionized water supplies 100%; Wherein, the mixture that described Chinese medicine ingredients extract contains Herba portulacae extract and Fructus cnidii extract.
Wherein, preferably, the content of the antiseptic described in raw material is 0.2～0.7%.
Wherein, preferably, described Chinese medicine ingredients extract also can contain Radix Sophorae Flavescentis extract, one or more of Fructus Phyllanthi extract and Spica Prunellae extract; Better, described Chinese medicine ingredients extract is the mixture of Herba portulacae extract, Fructus cnidii extract, Radix Sophorae Flavescentis extract, Fructus Phyllanthi extract and Spica Prunellae extract; Its addition mass ratio is preferably Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=((((0.1～10) ︰ (0.1～10), what addition ratio was better is (1～10) to 0.1～10) ︰ to 0.1～10) ︰ to 0.1～10) ︰: (1～10): (5～10): (0.1～5): (0.1～5).
Wherein, described Herba portulacae extract is this area routine, and general main component is flavonoid, polysaccharide, alkaloids, triterpene alcohols, organic acid, catecholamines.Preferably, described Herba portulacae extract is the Herba portulacae extract that BIOLAND company produces.
Wherein, described Fructus cnidii extract is this area routine, and general main component is osthole compounds.Preferably, described Fructus cnidii extract is the Fructus cnidii extract that Shaanxi Hua Tai company produces.
Wherein, described Fructus Phyllanthi extract is this area routine, and general main chemical compositions has vitamin C, several amino acids, glucose gallotannin, gallic acid etc.Preferably, described Fructus Phyllanthi extract is the Fructus Phyllanthi extract that MERCK company produces.
Wherein, described Radix Sophorae Flavescentis extract is this area routine, and general main effective ingredient is matrine and oxymatrine.Preferably, described Radix Sophorae Flavescentis extract is the Radix Sophorae Flavescentis extract that BIOLAND company produces.
Wherein, described Spica Prunellae extract is this area routine, and general main chemical compositions has triterpene and glycoside, sterol and glycoside, flavonoid etc.Preferably, described Spica Prunellae extract is the Spica Prunellae extract that Xi'an Si Nuote company produces.
Described plant sterol is the plant sterol of this area routine; The general main component of described plant sterol is cupreol, campesterol and stigmasterol.
Preferably, described plant sterol is the plant sterol that Semen sojae atricolor is extracted; The better plant sterol for BASF AG's production.
The amphoteric surfactant of described amphoteric surfactant this area routine; Be preferably cocamido propyl betaine and/or cocos nucifera oil acyl both sexes guanidine-acetic acid sodium class; Better, described cocos nucifera oil acyl both sexes guanidine-acetic acid sodium class is one or more in cocos nucifera oil acyl both sexes guanidine-acetic acid sodium, cocos nucifera oil acyl both sexes base sodium diacelate and cocos nucifera oil acyl both sexes base oxalic acid disodium.
Described anion surfactant is the anion surfactant of this area routine; Preferably, described anion surfactant is fatty alcohol polyoxyethylene ether sulfate and/or sarcosine salt; Better, described fatty alcohol polyoxyethylene ether sulfate is polyoxyethylenated alcohol sodium sulfate and/or AESA; Described sarcosine salt is one or more in sodium lauroyl sarcosine, potassium lauroyl sarcosine and cocos nucifera oil acylsarcosine sodium.
Described non-ionic surface active agent is the non-ionic surface active agent of this area routine; Preferably, described non-ionic surface active agent is alkyl polyglucoside and/or polysorbate-20.
Described polyhydric alcohol wetting agent is the polyhydric alcohol wetting agent of this area routine; Preferably, described polyhydric alcohol wetting agent is one or more in glycerol, 1,3 butylene glycol, 1,2-PD and sorbitol.
Described moisturizing agent is the moisturizing agent of this area routine; Preferably, described moisturizing agent is cetearyl alcohol.
Described pearling agent is the pearling agent of this area routine; Preferably, described pearling agent is glycol distearate and/or ethylene glycol monostearate.
Described viscosity modifier is the viscosity modifier of this area routine; Preferably, described viscosity modifier is sodium chloride.
Described antiseptic is the antiseptic of this area routine; Preferably, described antiseptic is that phenoxyethanol and Methylisothiazolinone are mixed.
Described chelating agen is the chelating agen of this area routine; Preferably, described chelating agen is EDETATE SODIUM.
Described conditioner is the conditioner of this area routine; Preferably, described conditioner is myristamide propyl group pg dimonium chloride phosphate ester.
Described foam stabilizer is the foam stabilizer of this area routine; Preferably, described foam stabilizer is Polyethylene Glycol-14M.
Described acid-base modifier is the acid-base modifier of this area routine; Preferably, described acid-base modifier is one or more in citric acid, triethanolamine and arginine.
Described essence is the essence of this area routine, as Fructus Citri Limoniae essence, rose essence, draft flavor essence etc.
Itching-relieving shower of the present invention reveals preparation method routinely and makes, and preferably, comprises the steps:
1) deionized water, amphoteric surfactant, non-ionic surface active agent, anion surfactant, polyhydric alcohol wetting agent, chelating agen, foam stabilizer are heated to 70-80 DEG C and dissolve to obtain A phase;
2) moisturizing agent and plant sterol are heated to 80-85 DEG C of insulation and dissolve to obtain B phase;
3) B phase is evenly mixed mutually with A, is incubated to solution and clarifies at 70-80 DEG C of temperature;
4) add pearling agent 70-80 DEG C of insulation 30min;
5) slow cooling, to 45-50 DEG C, adds conditioner, Chinese medicine ingredients extract, antiseptic, essence, acid-base modifier, viscosity modifier;
6) be cooled to 40 DEG C, discharging.
Meeting on the basis of this area general knowledge, above-mentioned each optimum condition, can combination in any, obtains the preferred embodiments of the invention.
Agents useful for same of the present invention and raw material be commercially available obtaining all.
Positive progressive effect of the present invention is:
It is remarkable that itching-relieving shower of the present invention reveals antihistamine, antibacterial, antibacterial, antiinflammatory and antiallergic effect, have derive from natural, to human body and environmental safety advantages of higher.
Detailed description of the invention
Mode below by embodiment further illustrates the present invention, but does not therefore limit the present invention among described scope of embodiments.The experimental technique of unreceipted actual conditions in the following example, according to conventional method and condition, or selects according to catalogue.
The Chinese medicine ingredients extract source of following embodiment:
Herba portulacae extract (BIOLAND company), Fructus cnidii extract (Shaanxi Hua Tai company), Radix Sophorae Flavescentis extract (BIOLAND company), Fructus Phyllanthi extract (MERCK company), Spica Prunellae extract (Xi'an Si Nuote company).
Embodiment 1
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
Above-mentioned each raw material sources, lower same.
The preparation method that itching-relieving shower reveals comprises the steps:
1. deionized water, amphoteric surfactant, non-ionic surface active agent, anion surfactant, wetting agent, chelating agen, foam stabilizer are heated to 70 DEG C and dissolve to obtain A phase;
2. moisturizing agent, emulsifying agent and plant sterol are heated to 80 DEG C of insulations and dissolve to obtain B phase;
3.B phase is evenly mixed mutually with A, is incubated to solution and clarifies at 70 DEG C of temperature;
4. add 70 DEG C of insulation 30min of pearling agent;
5. slow cooling to 45 DEG C, adds conditioner, Chinese medicine extract, antiseptic, essence, acid-base modifier, viscosity modifier;
6. be cooled to 40 DEG C, discharging.
Embodiment 2
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
content mass ratio is (Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=5:0.1:10:1:0.5)
The preparation method that itching-relieving shower reveals comprises the steps:
1. deionized water, amphoteric surfactant, non-ionic surface active agent, anion surfactant, wetting agent, chelating agen, foam stabilizer are heated to 80 DEG C and dissolve to obtain A phase;
2. moisturizing agent, emulsifying agent and plant sterol are heated to 85 DEG C of insulations and dissolve to obtain B phase;
3.B phase is evenly mixed mutually with A, is incubated to solution and clarifies at 80 DEG C of temperature;
4. add 80 DEG C of insulation 30min of pearling agent;
5. slow cooling to 50 DEG C, adds conditioner, Chinese medicine extract, antiseptic, essence, acid-base modifier, viscosity modifier;
6. be cooled to 40 DEG C, discharging.
Embodiment 3
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
The present invention takes each component according to following composition of raw materials:
content mass ratio is (Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=1:5:0.1:0.5:10)
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 4
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
content mass ratio is (Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=0.5:10:4:0.1:5)
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 5
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
content mass ratio is (Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=10:2:1:1.5:1.5)
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 6
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
content mass ratio is (Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=6:3:6:5:0.1)
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 7
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
content mass ratio is (Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=2:4:8:1:1)
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 8
This embodiment is substantially identical with the formula of embodiment 7, and its difference is that described Chinese medicine ingredients extract is Herba portulacae extract, the mixture of Fructus cnidii extract, and its content ratio is Herba portulacae extract: Fructus cnidii extract=3:7.
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 9
This embodiment is substantially identical with the formula of embodiment 7, its difference is that described Chinese medicine ingredients extract is Herba portulacae extract, Fructus cnidii extract, the mixture of Radix Sophorae Flavescentis extract, its content ratio is Herba portulacae extract: Fructus cnidii extract: Radix Sophorae Flavescentis extract=1.2:6.5:2.3.
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Effect embodiment
The antipruritic performance test methods that itching-relieving shower of the present invention reveals is as follows:
Experimental technique: 10 every group, the large thigh of Cavia porcellus back leg portion loses hair or feathers with 6% sodium sulfide, after 24h, smear sample in depilation place, after 3min, clean and dry with distilled water, once a day, continuous 2 days, after last administration 1h, with sand paper scratch depilation place, make it rubescent, taking not hemorrhage as degree, area is about 1.5cm × 1.5cm, and on wound face, drip 0.01% histamine phosphate liquid 0.05ml, after this every 3min with, 0.02%, 0.03%, 0.04% ... concentration increases progressively, all drip by every 0.05ml at every turn, until occur that Cavia porcellus later licks the phenomenon of back leg depilation place, finally to occur that Cavia porcellus later licks the right back histamine phosphate total amount being given when sufficient as itch-threshold, record is also respectively organized itch-threshold.
Sample preparation: five groups altogether, A group: normal saline; B group: bath gel matrix, is other parts of removing Chinese medicine ingredients and plant sterol in the formula of embodiment 7; C group: the bath gel of removing Chinese medicine ingredients in the formula of the embodiment of the present invention 7; D group: the bath gel of removing plant sterol in the formula of the embodiment of the present invention 7; E group: the bath gel of preparing with the formula of the embodiment of the present invention 7.
The antipruritic the performance test results that the itching-relieving shower that contains Chinese medicine ingredients and plant sterol reveals, as shown in table 1.
The antipruritic the performance test results that table 1 itching-relieving shower reveals
From the content shown in above-mentioned table 1, itching-relieving shower of the present invention reveals, and has demonstrated good antipruritic effect.
Claims (11)
1. an itching-relieving shower reveals, and by mass percentage, it contains following raw material components:
Amphoteric surfactant 1.0～20.0%, anion surfactant 6.0～20.0%, non-ionic surface active agent 0.5～8.0%, polyhydric alcohol wetting agent 0.1～8.0%, Chinese medicine ingredients extract 0.5～2.0%, moisturizing agent 0.1～2.0%, plant sterol 0.01～2.0%, chelating agen 0.01～0.5%, pearling agent 0～2.0%, viscosity modifier 0～2.0%, conditioner 0～0.5%, foam stabilizer 0～0.5%, essence 0～0.5%, acid-base modifier 0～0.2%, antiseptic 0～0.8%, deionized water supplies 100%; Wherein, the mixture that described Chinese medicine ingredients extract contains Herba portulacae extract and Fructus cnidii extract.
2. itching-relieving shower as claimed in claim 1 reveals, and it is characterized in that, described Chinese medicine ingredients extract also can contain Radix Sophorae Flavescentis extract, one or more in Fructus Phyllanthi extract and Spica Prunellae extract.
3. itching-relieving shower as claimed in claim 2 reveals, and it is characterized in that, described Chinese medicine ingredients extract is the mixture of Herba portulacae extract, Fructus cnidii extract, Radix Sophorae Flavescentis extract, Fructus Phyllanthi extract, Spica Prunellae extract.
4. itching-relieving shower as claimed in claim 3 reveals, it is characterized in that, the described each component addition of Chinese medicine ingredients extract mass ratio is Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=(0.1～10) ︰ (0.1～10) ︰ (0.1～10) ︰ (0.1～10) ︰ (0.1～10).
5. itching-relieving shower as claimed in claim 4 reveals, it is characterized in that, the described each component addition of Chinese medicine ingredients extract mass ratio is Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=(1～10): (1～10): (5～10): (0.1～5): (0.1～5).
6. itching-relieving shower as claimed in claim 2 reveals, and it is characterized in that, described Herba portulacae extract is the Herba portulacae extract that BIOLAND company produces; Described Fructus Phyllanthi extract is the Fructus Phyllanthi extract that MERCK company produces; Described Fructus cnidii extract is the Fructus cnidii extract that Shaanxi Hua Tai company produces; Described Radix Sophorae Flavescentis extract is the Radix Sophorae Flavescentis extract that BIOLAND company produces; Described Spica Prunellae extract is the Spica Prunellae extract that Xi'an Si Nuote company produces.
7. itching-relieving shower as claimed in claim 1 reveals, and it is characterized in that, described plant sterol is the plant sterol that Semen sojae atricolor is extracted.
8. itching-relieving shower as claimed in claim 7 reveals, and it is characterized in that, described plant sterol is the plant sterol that BASF AG produces.
9. itching-relieving shower as claimed in claim 1 reveals, and it is characterized in that, the content of described antiseptic is 0.2～0.7%; Described amphoteric surfactant is cocamido propyl betaine and/or cocos nucifera oil acyl both sexes guanidine-acetic acid sodium class; Described anion surfactant is fatty alcohol polyoxyethylene ether sulfate and/or sarcosine salt; Described non-ionic surface active agent is alkyl polyglucoside and/or polysorbate-20; Described polyhydric alcohol wetting agent is one or more in glycerol, 1,3 butylene glycol, 1,2-PD and sorbitol; Described moisturizing agent is cetearyl alcohol; Described pearling agent is glycol distearate and/or ethylene glycol monostearate; Described viscosity modifier is sodium chloride; Described antiseptic is that phenoxyethanol and Methylisothiazolinone are mixed; Described chelating agen is EDETATE SODIUM; Described conditioner is myristamide propyl group pg dimonium chloride phosphate ester; Described foam stabilizer is Polyethylene Glycol-14M; Described acid-base modifier is one or more in citric acid, triethanolamine and arginine.
10. itching-relieving shower as claimed in claim 9 reveals, and it is characterized in that, described cocos nucifera oil acyl both sexes guanidine-acetic acid sodium class is one or more in cocos nucifera oil acyl both sexes guanidine-acetic acid sodium, cocos nucifera oil acyl both sexes base sodium diacelate and cocos nucifera oil acyl both sexes base oxalic acid disodium; Described fatty alcohol polyoxyethylene ether sulfate is polyoxyethylenated alcohol sodium sulfate and/or AESA; Described sarcosine salt is one or more in sodium lauroyl sarcosine, potassium lauroyl sarcosine and cocos nucifera oil acylsarcosine sodium.
11. 1 kinds of preparation methoies that the itching-relieving shower as described in claim 1～10 any one reveals, is characterized in that, comprise the steps:
1) deionized water, amphoteric surfactant, non-ionic surface active agent, anion surfactant, polyhydric alcohol wetting agent, chelating agen, foam stabilizer are heated to 70-80 DEG C and dissolve to obtain A phase;
2) moisturizing agent and plant sterol are heated to 80-85 DEG C of insulation and dissolve to obtain B phase;
3) B phase is evenly mixed mutually with A, is incubated to solution and clarifies at 70-80 DEG C of temperature;
4) add pearling agent 70-80 DEG C of insulation 30min;
5) slow cooling, to 45-50 DEG C, adds conditioner, Chinese medicine ingredients extract, antiseptic, essence, acid-base modifier, viscosity modifier;
6) be cooled to 40 DEG C, discharging.
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| CN104042525B (en) * | 2014-07-08 | 2016-06-29 | 福州绿野生化技术有限公司 | A kind of antibacterial bath liquor and preparation method thereof |
| CN104146886B (en) * | 2014-07-21 | 2017-01-25 | 广东柏亚化妆品有限公司 | Miner bath lotion and production method thereof |
| CN104147103B (en) * | 2014-08-13 | 2017-12-22 | 新疆奥斯曼生物资源有限公司 | A kind of Chinese medicine composition and preparation method thereof of anti-dandruff sterilizing and itch-relieving, piliation |
| CN104224575B (en) * | 2014-09-12 | 2017-07-18 | 广州市天吻娇颜化妆品有限公司 | It is a kind of transparent without silicone oil hair-washing composition and preparation method thereof |
| CN104586678A (en) * | 2014-12-23 | 2015-05-06 | 李艳琼 | Shower gel capable of preventing and treating gynecopathy |
| CN104473793B (en) * | 2014-12-31 | 2018-06-05 | 广州品赫生物科技有限公司 | Oil/fat composition and its application in face cleaning product are assigned in a kind of moisturizing |
| CN104706552A (en) * | 2015-02-11 | 2015-06-17 | 上海彤颜实业有限公司 | Foam cleansing lotion and preparation method thereof |
| CN105534826A (en) * | 2016-02-02 | 2016-05-04 | 宁波美代进出口有限公司 | High-permeability environment-friendly antibacterial bath foam and preparation method thereof |
| CN106138219A (en) * | 2016-07-01 | 2016-11-23 | 扬州中汇生物技术有限公司 | A kind of infant itching-relieving cream and preparation method thereof |
| CN106176419A (en) * | 2016-08-23 | 2016-12-07 | 余姚市德派日用品有限公司 | A kind of bathing and hair-washing dew |
| CN106619319B (en) * | 2017-02-08 | 2019-09-20 | 广东科玮生物技术股份有限公司 | A kind of itching-relieving shower dew and preparation method thereof containing antibacterial peptide |
| CN107049886A (en) * | 2017-06-23 | 2017-08-18 | 合肥市风达农业有限责任公司 | A kind of antipruritic moisturizing sleeping Chinese medicine bath cream and preparation method thereof |
| CN107929182B (en) * | 2017-11-27 | 2020-08-07 | 绿馨颜（惠州）生物科技有限公司 | High-foaming high-fragrance-retention shower gel formula and preparation method thereof |
| CN107951792A (en) * | 2017-12-29 | 2018-04-24 | 广州市科能化妆品科研有限公司 | Anti-dandruff and itching-relieving hair-washing composition and preparation method thereof |
| CN108066228B (en) * | 2018-02-09 | 2020-06-12 | 杭州纳美智康科技有限公司 | Moisturizing antibacterial shower gel and preparation method thereof |
| CN109260107A (en) * | 2018-10-23 | 2019-01-25 | 南通季德胜科技有限公司 | A kind of formula of bath cream and preparation method with the antipruritic function of anti-mite |
| CN113081911A (en) * | 2021-03-09 | 2021-07-09 | 深圳职业技术学院 | Itching-relieving shower gel, preparation method thereof and shower bottle for containing itching-relieving shower gel |
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| CN1043956C (en) * | 1993-08-18 | 1999-07-07 | 林谷安 | "Jiefukang" |
| CN1133714A (en) * | 1995-01-04 | 1996-10-23 | 马水旺 | Health bath lotion |
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