CN103315932A - Itching-relieving body wash and preparation method thereof - Google Patents
Itching-relieving body wash and preparation method thereof Download PDFInfo
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- CN103315932A CN103315932A CN2013102224040A CN201310222404A CN103315932A CN 103315932 A CN103315932 A CN 103315932A CN 2013102224040 A CN2013102224040 A CN 2013102224040A CN 201310222404 A CN201310222404 A CN 201310222404A CN 103315932 A CN103315932 A CN 103315932A
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Abstract
The invention discloses an itching-relieving body wash and a preparation method thereof. The itching-relieving body wash comprises the raw materials of, by mass, 1.0-20.0% of an amphoteric surfactant, 6.0-20.0% of an anionic surfactant, 0.5-8.0% of a non-ionic surfactant, 0.1-8.0% of a polyol humectant, 0.5-2.0% of a traditional Chinese medicine extract, 0.1-2.0% of a moisture, 0.01-2.0% of phytosterol, 0.01-0.5% of a chelating agent, 0-2.0% of a pearlescent agent, 0-2.0% of a viscosity adjusting agent, 0-0.5% of a conditioning agent, 0-0.5% of a foam stabilizing agent, 0-0.5% of an essence, 0-0.2% of a pH adjusting agent, 0-0.8% of a preservative, and balance of deionized water. The traditional Chinese medicine extract comprises a mixture of a purslane extract and a common cnidium fruit extract. The itching-relieving body wash has excellent antihistamine, antibacterial, bacteria-inhibiting, anti-inflammatory, and anti-allergic effects.
Description
Technical field
The present invention relates to a kind of itching-relieving shower reveals and preparation method thereof.
Background technology
Along with the development of society and the raising of living standards of the people, consumer is also more and more higher to the requirement of daily nursing product, to the also more and more refinement of effect requirement of product.In this case, only have the bath gel of cleaning function just to be difficult to satisfy the demands of consumers.In recent years, have the bath gel of itching-relieving action also to occur successively, but antipruritic effect is not fine, bath gel the inside composition is difficult to bring into play its effect.
Summary of the invention
Technical problem to be solved by this invention is to have overcome in the prior art that the bath gel function is limited, antipruritic effect is not fine, bath gel the inside composition is difficult to bring into play the defective of its effect, provide a kind of antipruritic effect good, composition play a role itching-relieving shower reveal.
The invention provides a kind of itching-relieving shower and reveal, by mass percentage, it contains following raw material components:
Amphoteric surfactant 1.0～20.0%, anion surfactant 6.0～20.0%, non-ionic surface active agent 0.5～8.0%, polyhydric alcohol wetting agent 0.1～8.0%, Chinese medicine ingredients extract 0.5～2.0%, moisturizing agent 0.1～2.0%, plant sterol 0.01～2.0%, chelating agen 0.01～0.5%, pearling agent 0～2.0%, viscosity modifier 0～2.0%, conditioner 0～0.5%, foam stabilizer 0～0.5%, essence 0～0.5%, acid-base modifier 0～0.2%, antiseptic 0～0.8%, deionized water supplies 100%; Wherein, described Chinese medicine ingredients extract contains the mixture of Herba portulacae extract and Fructus cnidii extract.
Wherein, better, the content of the antiseptic described in the raw material is 0.2～0.7%.
Wherein, better, described Chinese medicine ingredients extract also can contain Radix Sophorae Flavescentis extract, one or more of Fructus Phyllanthi extract and Spica Prunellae extract; Better, described Chinese medicine ingredients extract is the mixture of Herba portulacae extract, Fructus cnidii extract, Radix Sophorae Flavescentis extract, Fructus Phyllanthi extract and Spica Prunellae extract; What its addition mass ratio was better is Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=((((0.1～10) ︰ (0.1～10), what the addition ratio was better is (1～10) to 0.1～10) ︰ to 0.1～10) ︰ to 0.1～10) ︰: (1～10): (5～10): (0.1～5): (0.1～5).
Wherein, described Herba portulacae extract is that this area is conventional, and general main component is flavonoid, polysaccharide, alkaloids, triterpene alcohols, organic acid, catecholamines.Better, described Herba portulacae extract is the Herba portulacae extract that BIOLAND company produces.
Wherein, described Fructus cnidii extract is that this area is conventional, and general main component is the osthole compounds.Better, described Fructus cnidii extract is the Fructus cnidii extract that Shaanxi Hua Tai company produces.
Wherein, described Fructus Phyllanthi extract is that this area is conventional, and general main chemical compositions has vitamin C, several amino acids, glucose gallotannin, gallic acid etc.Better, described Fructus Phyllanthi extract is the Fructus Phyllanthi extract that MERCK company produces.
Wherein, described Radix Sophorae Flavescentis extract is that this area is conventional, and general main effective ingredient is matrine and oxymatrine.Better, described Radix Sophorae Flavescentis extract is the Radix Sophorae Flavescentis extract that BIOLAND company produces.
Wherein, described Spica Prunellae extract is that this area is conventional, and general main chemical compositions has triterpene and glycoside, sterol and glycoside, flavonoid etc.Better, described Spica Prunellae extract is the Spica Prunellae extract that Xi'an Si Nuote company produces.
Described plant sterol is the plant sterol of this area routine; The general main component of described plant sterol is cupreol, campesterol and stigmasterol.
Better, described plant sterol is the plant sterol that Semen sojae atricolor is extracted; The better plant sterol for BASF AG's production.
The amphoteric surfactant of described amphoteric surfactant this area routine; Better is cocamido propyl betaine and/or cocos nucifera oil acyl both sexes guanidine-acetic acid sodium class; Better, described cocos nucifera oil acyl both sexes guanidine-acetic acid sodium class is one or more in cocos nucifera oil acyl both sexes guanidine-acetic acid sodium, cocos nucifera oil acyl both sexes base sodium diacelate and the cocos nucifera oil acyl both sexes base oxalic acid disodium.
Described anion surfactant is the anion surfactant of this area routine; Better, described anion surfactant is fatty alcohol polyoxyethylene ether sulfate and/or sarcosine salt; Better, described fatty alcohol polyoxyethylene ether sulfate is polyoxyethylenated alcohol sodium sulfate and/or AESA; Described sarcosine salt is one or more in sodium lauroyl sarcosine, potassium lauroyl sarcosine and the cocos nucifera oil acylsarcosine sodium.
Described non-ionic surface active agent is the non-ionic surface active agent of this area routine; Better, described non-ionic surface active agent is alkyl polyglucoside and/or polysorbate-20.
The polyhydric alcohol wetting agent that described polyhydric alcohol wetting agent is this area routine; Better, described polyhydric alcohol wetting agent is one or more in glycerol, 1,3 butylene glycol, 1,2-PD and the sorbitol.
Described moisturizing agent is the moisturizing agent of this area routine; Better, described moisturizing agent is cetearyl alcohol.
Described pearling agent is the pearling agent of this area routine; Better, described pearling agent is glycol distearate and/or ethylene glycol monostearate.
Described viscosity modifier is the viscosity modifier of this area routine; Better, described viscosity modifier is sodium chloride.
Described antiseptic is the antiseptic of this area routine; Better, described antiseptic is that phenoxyethanol and Methylisothiazolinone are mixed.
Described chelating agen is the chelating agen of this area routine; Better, described chelating agen is EDETATE SODIUM.
Described conditioner is the conditioner of this area routine; Better, described conditioner is myristamide propyl group pg dimonium chloride phosphate ester.
Described foam stabilizer is the foam stabilizer of this area routine; Better, described foam stabilizer is Polyethylene Glycol-14M.
Described acid-base modifier is the acid-base modifier of this area routine; Better, described acid-base modifier is one or more in citric acid, triethanolamine and the arginine.
Described essence is the essence of this area routine, such as Fructus Citri Limoniae essence, rose essence, draft flavor essence etc.
Itching-relieving shower dew of the present invention routinely preparation method makes, and is better, comprises the steps:
1) deionized water, amphoteric surfactant, non-ionic surface active agent, anion surfactant, polyhydric alcohol wetting agent, chelating agen, foam stabilizer are heated to 70-80 ℃ and dissolve to get the A phase;
2) moisturizing agent and plant sterol are heated to 80-85 ℃ of insulation dissolve B mutually;
3) the B phase is evenly mixed mutually with A, is incubated under the 70-80 ℃ of temperature to solution to clarify;
4) add 70-80 ℃ of insulation of pearling agent 30min;
5) slow cooling adds conditioner, Chinese medicine ingredients extract, antiseptic, essence, acid-base modifier, viscosity modifier to 45-50 ℃;
6) be cooled to 40 ℃, discharging.
On the basis that meets this area general knowledge, above-mentioned each optimum condition, but combination in any namely get the preferred embodiments of the invention.
Agents useful for same of the present invention and raw material be commercially available getting all.
Positive progressive effect of the present invention is:
It is remarkable that itching-relieving shower of the present invention reveals antihistamine, antibiotic, antibacterial, antiinflammatory and antiallergic effect, have derive from natural, to human body and environmental safety advantages of higher.
The specific embodiment
Mode below by embodiment further specifies the present invention, but does not therefore limit the present invention among the described scope of embodiments.The experimental technique of unreceipted actual conditions in the following example according to conventional method and condition, or is selected according to catalogue.
The Chinese medicine ingredients extract source of following embodiment:
Herba portulacae extract (BIOLAND company), Fructus cnidii extract (Shaanxi Hua Tai company), Radix Sophorae Flavescentis extract (BIOLAND company), Fructus Phyllanthi extract (MERCK company), Spica Prunellae extract (Xi'an Si Nuote company).
Embodiment 1
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
Above-mentioned each raw material sources, lower same.
The preparation method that itching-relieving shower reveals comprises the steps:
1. deionized water, amphoteric surfactant, non-ionic surface active agent, anion surfactant, wetting agent, chelating agen, foam stabilizer are heated to 70 ℃ and dissolve to get the A phase;
2. moisturizing agent, emulsifying agent and plant sterol are heated to 80 ℃ of insulations dissolve B mutually;
3.B evenly mix mutually with A, be incubated under 70 ℃ of temperature to solution and clarify;
4. add 70 ℃ of insulations of pearling agent 30min;
5. slow cooling to 45 ℃ adds conditioner, Chinese medicine extract, antiseptic, essence, acid-base modifier, viscosity modifier;
6. be cooled to 40 ℃, discharging.
Embodiment 2
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
The content mass ratio is (Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=5:0.1:10:1:0.5)
The preparation method that itching-relieving shower reveals comprises the steps:
1. deionized water, amphoteric surfactant, non-ionic surface active agent, anion surfactant, wetting agent, chelating agen, foam stabilizer are heated to 80 ℃ and dissolve to get the A phase;
2. moisturizing agent, emulsifying agent and plant sterol are heated to 85 ℃ of insulations dissolve B mutually;
3.B evenly mix mutually with A, be incubated under 80 ℃ of temperature to solution and clarify;
4. add 80 ℃ of insulations of pearling agent 30min;
5. slow cooling to 50 ℃ adds conditioner, Chinese medicine extract, antiseptic, essence, acid-base modifier, viscosity modifier;
6. be cooled to 40 ℃, discharging.
Embodiment 3
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
The present invention takes by weighing each component according to following composition of raw materials:
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 4
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 5
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 6
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
The content mass ratio is (Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=6:3:6:5:0.1)
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 7
A kind of itching-relieving shower of proposition of the present invention reveals, and by mass percentage, it contains following raw material components:
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 8
This embodiment basically prescription with embodiment 7 is identical, and its difference is that described Chinese medicine ingredients extract is Herba portulacae extract, the mixture of Fructus cnidii extract, and its content ratio is Herba portulacae extract: Fructus cnidii extract=3:7.
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Embodiment 9
This embodiment basically prescription with embodiment 7 is identical, its difference is that described Chinese medicine ingredients extract is Herba portulacae extract, Fructus cnidii extract, the mixture of Radix Sophorae Flavescentis extract, its content ratio is Herba portulacae extract: Fructus cnidii extract: Radix Sophorae Flavescentis extract=1.2:6.5:2.3.
The preparation method that the itching-relieving shower of the present embodiment reveals is with embodiment 1.
Effect embodiment
The antipruritic performance test methods that itching-relieving shower of the present invention reveals is as follows:
Experimental technique: 10 every group, the large thigh of Cavia porcellus back leg section loses hair or feathers with 6% sodium sulfide, smear sample in depilation place behind the 24h, clean and dry with distilled water behind the 3min, once a day, continuous 2 days, behind the last administration 1h, with sand paper scratch depilation place, make it rubescent, area is about 1.5cm * 1.5cm as degree take not hemorrhage, and drips 0.01% histamine phosphate liquid 0.05ml at wound face, after this every 3min with, 0.02%, 0.03%, 0.04% ... concentration increases progressively, all drip by every 0.05ml at every turn, until the phenomenon that Cavia porcellus later licks back leg depilation place occurs, later lick the right back histamine phosphate total amount that is given when sufficient as itch-threshold Cavia porcellus to occur at last, itch-threshold also respectively organized in record.
Sample preparation: five groups altogether, A group: normal saline; The B group: the bath gel matrix is other parts of removing Chinese medicine ingredients and plant sterol in the prescription of embodiment 7; C group: the bath gel of removing Chinese medicine ingredients in the prescription of the embodiment of the invention 7; D group: the bath gel of removing plant sterol in the prescription of the embodiment of the invention 7; E group: with the bath gel of the prescription preparation of the embodiment of the invention 7.
The antipruritic the performance test results that a kind of itching-relieving shower that contains Chinese medicine ingredients and plant sterol reveals, as shown in table 1.
The antipruritic the performance test results that table 1 itching-relieving shower reveals
By the content shown in the above-mentioned table 1 as can be known, itching-relieving shower of the present invention reveals, and has demonstrated good antipruritic effect.
Claims (10)
1. an itching-relieving shower reveals, and by mass percentage, it contains following raw material components:
Amphoteric surfactant 1.0～20.0%, anion surfactant 6.0～20.0%, non-ionic surface active agent 0.5～8.0%, polyhydric alcohol wetting agent 0.1～8.0%, Chinese medicine ingredients extract 0.5～2.0%, moisturizing agent 0.1～2.0%, plant sterol 0.01～2.0%, chelating agen 0.01～0.5%, pearling agent 0～2.0%, viscosity modifier 0～2.0%, conditioner 0～0.5%, foam stabilizer 0～0.5%, essence 0～0.5%, acid-base modifier 0～0.2%, antiseptic 0～0.8%, deionized water supplies 100%; Wherein, described Chinese medicine ingredients extract contains the mixture of Herba portulacae extract and Fructus cnidii extract.
2. itching-relieving shower as claimed in claim 1 reveals, and it is characterized in that, described Chinese medicine ingredients extract also can contain Radix Sophorae Flavescentis extract, one or more in Fructus Phyllanthi extract and the Spica Prunellae extract.
3. itching-relieving shower as claimed in claim 2 reveals, and it is characterized in that, described Chinese medicine ingredients extract is the mixture of Herba portulacae extract, Fructus cnidii extract, Radix Sophorae Flavescentis extract, Fructus Phyllanthi extract, Spica Prunellae extract.
4. itching-relieving shower as claimed in claim 3 reveals, it is characterized in that, each component addition mass ratio of described Chinese medicine ingredients extract is Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=(0.1～10) ︰ (0.1～10) ︰ (0.1～10) ︰ (0.1～10) ︰ (0.1～10); Better mass ratio is Radix Sophorae Flavescentis extract: Herba portulacae extract: Fructus cnidii extract: Fructus Phyllanthi extract: Spica Prunellae extract=(1～10): (1～10): (5～10): (0.1～5): (0.1～5).
5. itching-relieving shower as claimed in claim 2 reveals, and it is characterized in that, described Herba portulacae extract is the Herba portulacae extract that BIOLAND company produces; Described Fructus Phyllanthi extract is the Fructus Phyllanthi extract that MERCK company produces; Described Fructus cnidii extract is the Fructus cnidii extract that Shaanxi Hua Tai company produces; Described Radix Sophorae Flavescentis extract is the Radix Sophorae Flavescentis extract that BIOLAND company produces; Described Spica Prunellae extract is the Spica Prunellae extract that Xi'an Si Nuote company produces.
6. itching-relieving shower as claimed in claim 1 reveals, and it is characterized in that, described plant sterol is the plant sterol that Semen sojae atricolor is extracted.
7. itching-relieving shower as claimed in claim 6 reveals, and it is characterized in that, described plant sterol is the plant sterol that BASF AG produces.
8. itching-relieving shower as claimed in claim 1 reveals, and it is characterized in that, the content of described antiseptic is 0.2～0.7%; Described amphoteric surfactant is cocamido propyl betaine and/or cocos nucifera oil acyl both sexes guanidine-acetic acid sodium class; Described anion surfactant is fatty alcohol polyoxyethylene ether sulfate and/or sarcosine salt; Described non-ionic surface active agent is alkyl polyglucoside and/or polysorbate-20; Described polyhydric alcohol wetting agent is one or more in glycerol, 1,3 butylene glycol, 1,2-PD and the sorbitol; Described moisturizing agent is cetearyl alcohol; Described pearling agent is glycol distearate and/or ethylene glycol monostearate; Described viscosity modifier is sodium chloride; Described antiseptic is that phenoxyethanol and Methylisothiazolinone are mixed; Described chelating agen is EDETATE SODIUM; Described conditioner is myristamide propyl group pg dimonium chloride phosphate ester; Described foam stabilizer is Polyethylene Glycol-14M; Described acid-base modifier is one or more in citric acid, triethanolamine and the arginine.
9. itching-relieving shower as claimed in claim 8 reveals, and it is characterized in that, described cocos nucifera oil acyl both sexes guanidine-acetic acid sodium class is one or more in cocos nucifera oil acyl both sexes guanidine-acetic acid sodium, cocos nucifera oil acyl both sexes base sodium diacelate and the cocos nucifera oil acyl both sexes base oxalic acid disodium; Described fatty alcohol polyoxyethylene ether sulfate is polyoxyethylenated alcohol sodium sulfate and/or AESA, and described sarcosine salt is one or more in sodium lauroyl sarcosine, potassium lauroyl sarcosine and the cocos nucifera oil acylsarcosine sodium.
10. a preparation method of revealing such as each described itching-relieving shower of claim 1～9 is characterized in that, comprises the steps:
1) deionized water, amphoteric surfactant, non-ionic surface active agent, anion surfactant, polyhydric alcohol wetting agent, chelating agen, foam stabilizer are heated to 70-80 ℃ and dissolve to get the A phase;
2) moisturizing agent and plant sterol are heated to 80-85 ℃ of insulation dissolve B mutually;
3) the B phase is evenly mixed mutually with A, is incubated under the 70-80 ℃ of temperature to solution to clarify;
4) add 70-80 ℃ of insulation of pearling agent 30min;
5) slow cooling adds conditioner, Chinese medicine ingredients extract, antiseptic, essence, acid-base modifier, viscosity modifier to 45-50 ℃;
6) be cooled to 40 ℃, discharging.
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