CN106619337A - Crowfoot crack resistant cream for infants and a preparing method thereof - Google Patents
Crowfoot crack resistant cream for infants and a preparing method thereof Download PDFInfo
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- CN106619337A CN106619337A CN201510714236.6A CN201510714236A CN106619337A CN 106619337 A CN106619337 A CN 106619337A CN 201510714236 A CN201510714236 A CN 201510714236A CN 106619337 A CN106619337 A CN 106619337A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention relates to crowfoot crack resistant cream for infants and a preparing method thereof. The cream comprises solid grease, liquid grease, a solid emulsifier, a plant anti-allergy component, a humectant, a plant extract and an antiseptic. The cream is suitable for skin dryness, peeling, crowfoot cracks in severe cases of infants which are caused by dry weather in autumn and winter. The cream is particularly nourishing and mild, and is extremely high in safety requirements and good in grease compatibility and compatibleness. Oat glucan having high moisturizing effects and the polyol type humectant are adopted so that moisturizing effects are good. The liquorice root extract and natural bisabolol are added further to solve a sensitive skin problem.
Description
Technical field
The present invention relates to a kind of infant crease-proof cream, belongs to infant cosmetics of everyday use technical field, specifically
It is related to moisten moisturizing, prevents wrinkled skin, there is good protection to the tender and lovely skin of infant.
Background technology
With expanding economy and the improvement of people's living standards, the aggravation of current environmental pollution in addition, more
Come the health problem that more families begin to focus on infant, wherein the nursing to the tender and lovely skin of infant
Become more and more important.Especially to autumn and winter season, Changes in weather causes the drying of infant skin, sends out
It is red, peeling, or even the infant of northern Arid Area occurs the crowfoot cracks problem of skin, enterprise is also exerting
Power develops the product related to infant, also occurs many infant products in the market, and the head of a family is in choosing
The problems such as product can produce stimulation, initiation red swelling of the skin, prurituss to child's skin is often worried when selecting.And
The materials such as the ethanol contained in the mainly formula for causing these problems, pigment, chemical industry quintessence oil are to baby's skin
The serious stimulation of skin.Therefore, solve the problems, such as that infant wrinkled skin safety is the problem of overriding concern.
The content of the invention
It is an object of the invention to provide a kind of infant crease-proof cream, for infant wrinkled skin problem,
Add in formula and especially moisten composition, coordinate various plants origin components, reduce skin irritation, by this
Effectively wrinkle resistant and gentle safe, protection infant children's delicate skin is realized in invention.
Present invention employs following technical scheme：
A kind of crease-proof cream that infant is used, its composition constitutes by mass percentage as follows：
Wherein, the solid grease selects fatty alcohol, medical ventolin, shea butter, fatty acid glycerine
One or more in ester, native paraffin or synthetic wax；
The liquid fat selection isopropyl palmitate, caprylic capric triglyceride, carbonic acid dibutyl ester, in vain
Oil, silicone oil, almond oil, Camellia oil, isopropyl palmitate, iso-octyl palmitate, olive oil, castor
Oleum Sesami, soybean oil, Semen Tritici aestivi germ oil, isomery hexadecane hydrocarbon, alkyl benzoate, the isobutyl of adipic acid two
Ester, lauric acid hexyl ester, sad myristin, the different monooctyl ester of cocoyl, American Avocado Tree oil, soybean oil, walnut oil
In one or more；
The solid state emulsifying agent selects glyceryl stearate, sucrose monostearate, PEG-100 stearic acid
Ester, sorbitan fatty acid ester, polyoxyethylene sorbitan sorbic alcohol fatty acid ester, aliphatic alcohol polyethenoxy
Ether, cithrol, sucrose monostearate, arachidic alcohol glucoside, polyglycerin ester, hydrogenation
One or more in lecithin；
The wetting agent selects glycerol, Propylene Glycol, one or more in butanediol；
The rheology control agent selects organic natural water-soluble copolymer, organic semi-synthetic water-soluble polymeric
One of thing, organic synthesiss class water-soluble polymer；
The active components of plants：The active components of plants is oat beta-glucan class, and plant sterol is red
Bisabolol, licorice root extract, Radix et Caulis Opuntiae Dillenii extract, Herba Centellae extract, in Aloe extract
Plant or several.
Alternatively, described solid grease be cetearyl alcohol, medical ventolin, in shea butter
Plant or several.
Alternatively, described liquid fat be caprylic capric triglyceride, carbonic acid dibutyl ester, white oil, silicon
Several mixture in oil.
Alternatively, described solid state emulsifying agent be glyceryl stearate, sucrose monostearate, PEG-100
Stearate, one or more mixture in polyglycerin ester.
Alternatively, the solid emulsifier is hydrolecithin, and the active components of plants is plant sterol,
And the hydrolecithin and plant sterol compounding use.
Alternatively, hydrolecithin of the crease-proof cream comprising pure plant origin, plant sterol, licorice
Extract, vitamin E acetate, two or more in natural bisabolol.
The invention also discloses a kind of preparation method of infant crease-proof cream, walks including following several preparation
Suddenly：
(1) preparation of oil-based system：By solid grease, liquid fat, the oil of solid state emulsifying agent composition
Phase heating in water bath obtains final product oil-based system to 70-95 DEG C；
(2) preparation of aqueous phase system：By rheology control agent be distributed to deionized water and wetting agent composition
In water phase, 60-90 DEG C is heated to, obtains final product aqueous phase system；
(3) water phase, the formation of oil phase mixed system：With rotating speed as 5000-8000r/min homogenizing described in
Add oil-based system obtained by the step (1) while the aqueous phase system that step (2) is obtained, then with
Rotating speed is 5000-8000r/min homogenizing 10min；
(4) crease-proof cream for baby is obtained；
(5) the mixed system natural cooling of the step (3) is cooled to below 50 degrees Celsius of temperature
When, the material with antisepsises is added, afterwards near less than 30 DEG C add plant extract, essence,
10-40min is stirred with rotating speed 200-800r/min, then naturally cools to room temperature and obtain of the invention one
Plant infant crease-proof cream.
By above-mentioned technical proposal, the infant crease-proof cream of the present invention at least has advantages below：
The infant crease-proof cream of the present invention, in component the compounding of various wetting agents plus oat beta-glucan and
The various moisturizings of natural phytosterin, moistening effect preferably, not there is a problem of being dried decortication after use, add
Plus the medicinal herb componentses such as Radix Glycyrrhizae extract and bisabolol, play a part of good anti-inflammation, add
Radix et Caulis Opuntiae Dillenii extract, reparation and protective effect of the Herba Centellae extract to young tender skin is more thoughtful complete.
Heretofore described raw material：Lecithin is the Main Ingredients and Appearance for constituting cell membrane, maintains moisture, profit
Skin is good with skin affinity；Plant sterol has significant antipruritic, releives, antiallergic sense and antiphlogistic effects.
Lecithin and plant sterol one work to form bi-layer membrane, maintain the bimolecular structure of lipid, this pair
Molecular layer is similar to human body cell film component, structure, very good with the affinity of skin, profit in the present invention
Played a part of to protect and repair skin barrier with the special ratios of both materials.
The effect of vitamin E acetate：Good antioxidant, removes free radical anti-inflammatory, helps wound healing,
Soft skin, promotes blood microcirculation.
The effect of natural bisabolol：With anti-inflammatory activity, Radix Glycyrrhizae extract is coordinated to adjust exempting from for skin
Epidemic disease function, diminishes inflammation, pre- hypo-allergenic, and the poison that can release cosmetics and other extraneous factors to skin is secondary
Effect.
Radix et Caulis Opuntiae Dillenii extract：With moisturizing, detumescence is releived, the effects such as scar of dispelling；
Herba Centellae extract：The effects such as with promoting wound healing, reducing cicatrization, anti-inflammation；
Cetearyl alcohol in instant component, hydrolecithin, plant sterol, natural bisabolol is sweet
Careless extract, oat beta-glucan adds the sample and blank obtained in formula according to specific proportioning of the invention
The moistening effect of cream group and the repairing effect to skin barrier are compared, and effect is significantly better than blank product
Product.Data are as follows：
Described above is only the general introduction of technical solution of the present invention, in order to more clearly understand the present invention's
Technological means, and can be practiced according to the content of description, it is detailed with presently preferred embodiments of the present invention below
Describe in detail bright as after.
Description of the drawings
Fig. 1 is the moisturizing experiment comparison diagram of embodiment 1 and the infant crease-proof cream of embodiment 2；
Fig. 2 compares for the skin barrier function reparative experiment of embodiment 1 and the infant crease-proof cream of embodiment 2
Figure.
Specific embodiment
It is right for the present invention is expanded on further to reach technological means and effect that predetermined goal of the invention is taken
According to infant proposed by the present invention crease-proof cream its specific embodiment, feature and its effect, specifically
It is bright as after.
Unless otherwise stated, the percentage composition in the present invention is weight percentage.
Preparation of the embodiment 1 containing plant sterol with the infant crease-proof cream of hydrolecithin
Formula：
Preparation method：
1st, by A phases and B phases be separately heated to 85 DEG C it is stand-by
2nd, B is added to A phases, homogenizing 3-5min
3rd, 45 DEG C are cooled to, C phases are added
Preparation of the embodiment 2 without plant sterol with the infant crease-proof cream of hydrolecithin
The preparation method of embodiment 2 is with embodiment 1
Effect example 1：The moisturizing experiment and skin barrier reparation of embodiment 1 and the crease-proof cream of embodiment 2
Experiment is compared.
Laboratory sample：Embodiment 1 and the sample of embodiment 2
Object：12 volunteer positions：Inboard arm
Experimental design：Daily early, evening is washed one's hands arm 2 times using detergent, uses embodiment 1 after washing respectively
With the cream of embodiment 2, using 7 days.
Experimental result：
1st, change of moisture content：Compare with the cream group of embodiment 2, the water content of the cream group of embodiment 1
21.0%, 22.5% and 22.4% was increased respectively at 1,4 and 7 days., illustrate plant sterol and hydrogenation ovum
Phospholipid has preferable replenishing water and preserving moisture effect.See accompanying drawing 1.
2nd, skin barrier function reparation：1 group of TEWL of embodiment illustrates skin with using front basically identical
Barrier is not affected by destruction, and receives destruction using the skin barrier of embodiment 2；With the cream of embodiment 2
White group is compared, and 1 group of TEWL of embodiment reduced respectively 8.8%, 9.7% and 13.6% at 1,4 and 7 days,
Illustrate that plant sterol and hydrolecithin also have functions that to repair skin barrier, see accompanying drawing 2.
The efficacy assessments result of effect example 2
Remission effect to chapped skin symptom：Volunteer to 10 hand and foot crowfoot cracks, uses daily
Product of the present invention twice, after ten days, embodiment 1 can effectively repair chapped skin symptom, implement
Example 2 is then substantially without repairing effect.
The zest of effect example 3, sensitivity test
The Jing irritant experiments of embodiment 1 are verified：It is non-stimulated and anaphylaxiss.
The skin of effect example 4 sensing examination resultant effect is investigated
Smear is good, and moistness is good, and dermal sensation is more continuous soft after painting.
Embodiment 1 is evaluated following with investigation, effect of the anti-chapped frost in 2.After consumer's use
Experiment methods of marking, choose 40 20-50 year age brackets volunteer as applicable object (because baby children
Youngster can not describe use aesthetic), try out embodiment 1, the anti-chapped frost in 2 respectively, and make it is reasonable
Marking.
Every using effect total score is 5 points：5 points be effect preferably, represent very satisfied, 4 points be it is preferable,
3 points is to receive, and 3 points is once to receive.It is below every average, the results are shown in Table 1.
As a result show that the anti-chapped frost that embodiment 1 makes is better than embodiment 2, but both in terms of moisturizing and moistness
It is gentle non-stimulated.
Table 1
| Skin sense is evaluated | Embodiment 1 | Embodiment 2 |
| Moisture retention | 5 | 4 |
| Moistness | 5 | 4 |
| Smear | 4.5 | 4.3 |
| Use rear mildness | 5 | 5 |
Presently preferred embodiments of the present invention is these are only, it is all the present invention's not to limit the present invention
Within spirit and principle, any modification, equivalent substitution and improvements made etc. should be included in this
Within bright protection domain.
Claims (7)
1. the crease-proof cream that a kind of infant is used, it is characterised in that its composition is constituted by mass percentage
It is as follows：
Wherein, the solid grease selects fatty alcohol, medical ventolin, shea butter, fatty acid glycerine
One or more in ester, native paraffin or synthetic wax；
The liquid fat selection isopropyl palmitate, caprylic capric triglyceride, carbonic acid dibutyl ester, in vain
Oil, silicone oil, almond oil, Camellia oil, isopropyl palmitate, iso-octyl palmitate, olive oil, castor
Oleum Sesami, soybean oil, Semen Tritici aestivi germ oil, isomery hexadecane hydrocarbon, alkyl benzoate, the isobutyl of adipic acid two
Ester, lauric acid hexyl ester, sad myristin, the different monooctyl ester of cocoyl, American Avocado Tree oil, soybean oil, walnut oil
In one or more；
The solid state emulsifying agent selects glyceryl stearate, sucrose monostearate, PEG-100 stearic acid
Ester, sorbitan fatty acid ester, polyoxyethylene sorbitan sorbic alcohol fatty acid ester, aliphatic alcohol polyethenoxy
Ether, cithrol, sucrose monostearate, arachidic alcohol glucoside, polyglycerin ester, hydrogenation
One or more in lecithin；
The wetting agent selects glycerol, Propylene Glycol, one or more in butanediol；
The rheology control agent selects organic natural water-soluble copolymer, organic semi-synthetic water-soluble polymeric
One of thing, organic synthesiss class water-soluble polymer；
The active components of plants：The active components of plants is oat beta-glucan class, and plant sterol is red
Bisabolol, licorice root extract, Radix et Caulis Opuntiae Dillenii extract, Herba Centellae extract, in Aloe extract
Plant or several.
2. crease-proof cream as claimed in claim 1, it is characterised in that described solid grease is spermaceti
Stearyl alcohol, medical ventolin, one or more in shea butter.
3. crease-proof cream as claimed in claim 1, it is characterised in that described liquid fat is octanoic acid
Capric acid triglyceride, carbonic acid dibutyl ester, white oil, several mixture in silicone oil.
4. crease-proof cream as described in claim 1, it is characterised in that described solid state emulsifying agent is
Glyceryl stearate, sucrose monostearate, PEG-100 stearates, one kind in polyglycerin ester or
Several mixture.
5. crease-proof cream as claimed in claim 1, it is characterised in that the solid emulsifier is hydrogenation
Lecithin, the active components of plants be plant sterol, and the hydrolecithin and plant sterol compounding
Use.
6. crease-proof cream as claimed in claim 1, it is characterised in that the crease-proof cream includes pure plant
The hydrolecithin in source, plant sterol, licorice root extract, vitamin E acetate, in natural bisabolol
Two or more.
7. the preparation method of crease-proof cream as claimed in claim 1, it is characterised in that including following several
Individual preparation process：
(1) preparation of oil-based system：By solid grease, liquid fat, the oil of solid state emulsifying agent composition
Phase heating in water bath obtains final product oil-based system to 70-95 DEG C；
(2) preparation of aqueous phase system：By rheology control agent be distributed to deionized water and wetting agent composition
In water phase, 60-90 DEG C is heated to, obtains final product aqueous phase system；
(3) water phase, the formation of oil phase mixed system：With rotating speed as 5000-8000r/min homogenizing described in
Add oil-based system obtained by the step (1) while the aqueous phase system that step (2) is obtained, then with
Rotating speed is 5000-8000r/min homogenizing 10min；
(4) infant crease-proof cream is obtained；
(5) the mixed system natural cooling of the step (3) is cooled to below 50 degrees Celsius of temperature
When, the material with antisepsises is added, afterwards near less than 30 DEG C add plant extract, essence,
10-40min is stirred with rotating speed 200-800r/min, then naturally cools to room temperature and obtain of the invention one
Plant infant crease-proof cream.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510714236.6A CN106619337A (en) | 2015-10-28 | 2015-10-28 | Crowfoot crack resistant cream for infants and a preparing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510714236.6A CN106619337A (en) | 2015-10-28 | 2015-10-28 | Crowfoot crack resistant cream for infants and a preparing method thereof |
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| CN106619337A true CN106619337A (en) | 2017-05-10 |
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| CN201510714236.6A Pending CN106619337A (en) | 2015-10-28 | 2015-10-28 | Crowfoot crack resistant cream for infants and a preparing method thereof |
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107049903A (en) * | 2017-05-16 | 2017-08-18 | 曼秀雷敦(中国)药业有限公司 | A kind of cream for being used for sensitive skin and preparation method thereof |
| CN107433661A (en) * | 2017-09-19 | 2017-12-05 | 安徽嘉美工艺品有限公司 | A kind of solid wood furniture anticracking bending method |
| CN107440955A (en) * | 2017-07-28 | 2017-12-08 | 武汉医佳宝生物材料有限公司 | A kind of antiallergic restorative facial cream |
| CN108066270A (en) * | 2017-12-27 | 2018-05-25 | 吕玲 | A kind of multiple-effect infant moisture surge treatment formula and preparation method thereof |
| CN108096135A (en) * | 2017-12-08 | 2018-06-01 | 福州英荷日用化学品有限公司 | A kind of skin care deicing paste and preparation method thereof |
| CN108542797A (en) * | 2018-05-28 | 2018-09-18 | 绿映（上海）生物科技有限公司 | A kind of composition containing licorice and the skin protection cosmetics containing the composition and preparation method |
| CN108703898A (en) * | 2018-08-30 | 2018-10-26 | 广州市华晟健康产业有限公司 | A kind of children's moisturiser containing camellia |
| CN108771649A (en) * | 2018-08-30 | 2018-11-09 | 广州市华晟健康产业有限公司 | A kind of children containing newborn wooden fruit moisten frost again |
| CN109091411A (en) * | 2018-11-13 | 2018-12-28 | 王亚平 | A kind of infant's lotion and preparation method thereof |
| CN109966231A (en) * | 2019-04-11 | 2019-07-05 | 冯江 | A kind of bright face skin beautifying cream and preparation method thereof |
| CN110115705A (en) * | 2019-06-19 | 2019-08-13 | 广东默默化妆品有限公司 | A kind of emulsifying process of maintenance frost |
| CN111084738A (en) * | 2018-10-24 | 2020-05-01 | 福建省梦娇兰日用化学品有限公司 | Infant care cream containing herbal components |
| CN111228154A (en) * | 2020-03-12 | 2020-06-05 | 广东袋鼠妈妈生物科技有限公司 | Fresh wheat extract protoplasm milk for infants and preparation method thereof |
| CN113041193A (en) * | 2021-03-26 | 2021-06-29 | 北京东方淼森生物科技有限公司 | Anti-irritation composition and preparation method and application thereof |
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107049903A (en) * | 2017-05-16 | 2017-08-18 | 曼秀雷敦(中国)药业有限公司 | A kind of cream for being used for sensitive skin and preparation method thereof |
| CN107440955A (en) * | 2017-07-28 | 2017-12-08 | 武汉医佳宝生物材料有限公司 | A kind of antiallergic restorative facial cream |
| CN107433661A (en) * | 2017-09-19 | 2017-12-05 | 安徽嘉美工艺品有限公司 | A kind of solid wood furniture anticracking bending method |
| CN108096135A (en) * | 2017-12-08 | 2018-06-01 | 福州英荷日用化学品有限公司 | A kind of skin care deicing paste and preparation method thereof |
| CN108066270A (en) * | 2017-12-27 | 2018-05-25 | 吕玲 | A kind of multiple-effect infant moisture surge treatment formula and preparation method thereof |
| CN108542797A (en) * | 2018-05-28 | 2018-09-18 | 绿映（上海）生物科技有限公司 | A kind of composition containing licorice and the skin protection cosmetics containing the composition and preparation method |
| CN108703898A (en) * | 2018-08-30 | 2018-10-26 | 广州市华晟健康产业有限公司 | A kind of children's moisturiser containing camellia |
| CN108771649A (en) * | 2018-08-30 | 2018-11-09 | 广州市华晟健康产业有限公司 | A kind of children containing newborn wooden fruit moisten frost again |
| CN111084738A (en) * | 2018-10-24 | 2020-05-01 | 福建省梦娇兰日用化学品有限公司 | Infant care cream containing herbal components |
| CN109091411A (en) * | 2018-11-13 | 2018-12-28 | 王亚平 | A kind of infant's lotion and preparation method thereof |
| CN109966231A (en) * | 2019-04-11 | 2019-07-05 | 冯江 | A kind of bright face skin beautifying cream and preparation method thereof |
| CN110115705A (en) * | 2019-06-19 | 2019-08-13 | 广东默默化妆品有限公司 | A kind of emulsifying process of maintenance frost |
| CN111228154A (en) * | 2020-03-12 | 2020-06-05 | 广东袋鼠妈妈生物科技有限公司 | Fresh wheat extract protoplasm milk for infants and preparation method thereof |
| CN113041193A (en) * | 2021-03-26 | 2021-06-29 | 北京东方淼森生物科技有限公司 | Anti-irritation composition and preparation method and application thereof |
| CN113041193B (en) * | 2021-03-26 | 2022-03-11 | 北京东方淼森生物科技有限公司 | Anti-irritation composition and preparation method and application thereof |
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Address after: 363000 Lantian Economic Development Zone, Fujian, Zhangzhou Applicant after: Frog Prince (China) Daily Chemicals Co., Ltd. Applicant after: Laibo cosmeceutical Technology (Shanghai) Limited by Share Ltd Address before: 363005 No. 8 North Bridge Road, Longwen District, Fujian, Zhangzhou Applicant before: Frog Prince (China) Daily Chemicals Co., Ltd. Applicant before: Laibo Industrial (Shanghai) Limited by Share Ltd |
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Effective date of registration: 20190314 Address after: 363005 No. 8 Wuqiao North Road, Lantian Economic Development Zone, Zhangzhou City, Fujian Province Applicant after: Frog Prince (Fujian) Infant Care Products Co., Ltd. Applicant after: Laibo cosmeceutical Technology (Shanghai) Limited by Share Ltd Address before: 363000 Lantian Economic Development Zone, Zhangzhou City, Fujian Province Applicant before: Frog Prince (China) Daily Chemicals Co., Ltd. Applicant before: Laibo cosmeceutical Technology (Shanghai) Limited by Share Ltd |
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Application publication date: 20170510 |