CN111228154A

CN111228154A - Fresh wheat extract protoplasm milk for infants and preparation method thereof

Info

Publication number: CN111228154A
Application number: CN202010170718.0A
Authority: CN
Inventors: 罗成东; 孙永; 潘美红; 徐小建
Original assignee: Guangdong Kangaroo Mommy Biotechnology Co ltd
Current assignee: Guangdong Kangaroo Mommy Biotechnology Co ltd
Priority date: 2020-03-12
Filing date: 2020-03-12
Publication date: 2020-06-05

Abstract

The invention provides fresh extracted virgin pulp milk of wheat for infants and a preparation method thereof. The raw milk comprises: wheat germ oil, a skin conditioner, grease, an emulsifier, a thickener and a humectant; the skin conditioning agent comprises: wheat germ extract, plant antiallergic agent, mushroom dextran, XINMINSHU, DEFUXIU, Terminalia catappa fruit extract, hydrolyzed wheat protein, wheat ceramide and antibacterial composition. The components of the wheat fresh extract protoplasm milk for the infants are mutually matched, so that the skin pressure can be relieved more effectively by synergistic interaction, the skin barrier capability of the infants can be effectively improved, the stimulation brought by the outside is reduced, the sensitive, tender and fragile skin of the infants is protected, the infants are more safely, better and more effectively cared, and the wheat fresh extract protoplasm milk is easy to absorb and can be used for keeping moisture for a long time.

Description

Fresh wheat extract protoplasm milk for infants and preparation method thereof

Technical Field

The invention belongs to the field of cosmetics, and particularly relates to a fresh extract protoplasm milk of wheat for infants and a preparation method thereof.

Background

The skin of the baby is very delicate and easy to be damaged when being smooth and fine. The infant skin has poor acid-base control capability, and the skin care product with too high alkaline concentration is avoided, otherwise, the skin protection film is damaged, and skin diseases and the like occur. The skin temperature regulating ability of the infant is poor, the sweat glands and blood vessels of the skin are not completely developed, the regulating ability on the temperature is low, the immune system is not completely developed, and the resistance is weak, so that allergic eczema, dermatitis, erythema blisters and the like can easily appear. Furthermore, since infants are not fully developed and cannot control their excretion, residual excreta and the infants often suffer from running water due to long teeth, which may irritate the skin, causing skin problems such as erosion, ulcer, chapping, and the like.

The skin of the baby is weaker than that of the adult, so that the skin care product special for the baby cannot be directly used, and the skin care product special for the baby is selected, has very little or no irritation to the baby, can keep the skin moist, forms a protective film, can effectively protect a sebum layer, can reduce and prevent skin diseases, improves the skin state of the baby and helps the baby to relieve the skin. However, in the current market, a few moisturizing skin care products suitable for infants are available, and most of the moisturizing skin care products consist of deionized water, an emulsifier, a humectant, a thickener, a preservative, essence, a skin conditioner and the like.

CN109925245A discloses a sleeping baby skin lotion and a preparation method thereof, wherein the components of the sleeping baby skin lotion comprise 3-5 parts of caprylic/capric triglyceride, 3-5 parts of shea butter, 2-5 parts of squalane, 0.1-0.3 part of wheat germ oil, 0.01-0.3 part of sodium hyaluronate, 0.01-0.3 part of arginine, 0.1-1 part of wheat gluten, 0.1-1 part of chamomile extract, 1-3 parts of polydimethylsiloxane, 2-11 parts of emulsifier, 1-6 parts of polyalcohol humectant, and also can comprise tocopherol acetate, thickener and the like. The formula of the invention contains various plant oil and plant extract with moisturizing and nourishing functions, is easy to be absorbed by human body, and has good moisturizing and protecting effects on skin.

CN104606081A discloses a baby massage emollient oil, which is composed of almond kernel oil, grape seed oil, wheat germ oil, water, sunflower seed oil, rosemary leaf extract, vitamin E, soybean oil, β -carotene, canola oil and limonene, and the baby massage emollient oil is 100% natural in components, mild and non-irritating to baby skin, good in absorptivity, and excellent in moisturizing effect and lubricating effect.

CN107334677A discloses an infant moisturizing skin cream, which comprises the following components in percentage by weight: 2-3% of an emulsifier; 3-8% of a humectant; 5 to 15 percent of thickening agent; 0.2-0.3% of preservative and 5-8% of emollient oil; 0.1-0.2% of pH regulator and 3-8% of natural extract. The balance of distilled water; the natural extract comprises the following components in percentage by weight: 35-40% of centella extract, 15-18% of German chamomile extract, 30-34% of platycodon grandiflorum extract and 8-15% of lemon extract. The skin cream has the advantages of good moisturizing effect, good allergy relieving effect, good repairing effect and high moistening degree.

Therefore, there is a need to develop a primary pulp milk which is free of artificial essence, non-natural pigment, preservative and mineral oil petrolatum, and brings safer, better and more effective protection for babies.

Disclosure of Invention

Aiming at the defects of the prior art, the invention aims to provide the fresh extract original milk of the wheat for the infants and the preparation method thereof.

In order to achieve the purpose, the invention adopts the following technical scheme:

in a first aspect, the invention provides a freshly extracted virgin pulp milk of baby wheat, comprising: wheat germ oil, a skin conditioner, grease, an emulsifier, a thickener and a humectant;

the skin conditioning agent comprises: wheat germ extract, plant antiallergic agent, mushroom dextran, XINMINSHU, DEFUXIU, Terminalia catappa fruit extract, hydrolyzed wheat protein, wheat ceramide and antibacterial composition.

In the invention, the baby hip cream is added with wheat germ oil, a skin conditioner and grease, and all the components are matched with each other, so that the baby hip cream has a synergistic interaction effect, has a strong anti-inflammatory and soothing effect, can strengthen a skin barrier through immune regulation and soothing, has no primary stimulation, and is beneficial to recovering symptoms of atopic dermatitis; the skin care product has good anti-inflammatory effect, can effectively relieve the stimulation of the outside to the skin, and can increase the anti-irritation and anti-inflammatory capability of the skin; the structure of the dermis can be strengthened, and the skin can be protected from oxidation pressure; has good moistening and moisturizing effects, and can strengthen the skin protective barrier and better resist external invasion after long-term use.

In the present invention, the skin conditioning agent comprises: wheat germ extract, plant antiallergic agent, mushroom dextran, XINMINSHU, DEFUXIU, Terminalia catappa fruit extract, hydrolyzed wheat protein, wheat ceramide and antibacterial composition.

Wherein the wheat germ extract contains wheat derived components including proteins, amino acids, minerals, oligo-and polysaccharides, phenolic compounds, and tocopherol, and has structure reconstruction and regeneration effects, and soothing and protecting effects.

The plant anti-allergy agent is a plant-derived allergy-relieving product of the Korean bailousi extract, contains a centella asiatica extract, a liquorice extract, a chamomile extract, a scutellaria baicalensis extract, a rosemary extract, a tea extract and a polygonum cuspidatum extract, can repair skin damage caused by atopic dermatitis, and has good effects on anti-allergy and anti-allergy of sensitive skin and treatment of hormone-dependent dermatitis.

Wherein, the mushroom glucan is β -glucan derived from Schizophyllum commune, has strong moisturizing capability, improves the moisture of skin cells, eliminates skin inflammation and tissue edema, and enables the skin to be glossy, fine and elastic.

Wherein, the medicine for treating allergy consists of bisabolol and ginger (ginger OFFICINALE) root extract, has better anti-inflammatory effect, can effectively relieve the stimulation of the external world to the skin, and can increase the anti-irritation and anti-inflammatory capability of the skin;

the Defushi is composed of hexyldecanol, bisabolol, cetyl N-palmitoyl hydroxyproline, stearic acid and rape (BRASSICA campestis) sterols, has a structure similar to that of natural ceramide 2, can effectively improve the softness of the skin and enhance the barrier function of the skin, and has a certain anti-inflammatory effect;

wherein the wheat ceramide is composed of glycolipid and glycosphingolipid, is derived from wheat grain extract, can reduce skin moisture loss, strengthens skin barrier by supplementing the intercellular colloid of ceramide, can rebuild dermis barrier by stimulating the synthesis of collagenase inhibitor TIMP-1, strengthens dermis structure, and can protect skin from oxidation pressure.

The antibacterial composition is a skin micro-ecological balance regulator prepared from Guangzhou He vast company, contains patchouli extract, citronella extract and magnolia extract, and can inhibit the growth of pathogenic bacteria and improve the skin micro-ecological balance.

Preferably, the raw milk comprises the following components in percentage by mass: 5-25% of grease, 1-10% of skin conditioner, 0.5-5.0% of emulsifier, 0.5-1.0% of thickener, 8-20% of humectant and the balance of wheat germ oil.

In the present invention, the amount of the oil or fat added is 5 to 25%, for example, 5%, 6%, 7%, 8%, 9%, 10%, 12%, 14%, 16%, 18%, 20%, 21%, 23%, 25% or the like, based on 100% by mass of the total raw milk.

In the present invention, the skin conditioner may be added in an amount of 1 to 10%, for example, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, etc., based on 100% by mass of the total raw milk.

In the present invention, the amount of the emulsifier added is 0.5 to 5.0%, for example, 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5.0%, or the like, based on 100% by mass of the total raw stock milk.

In the present invention, the amount of the thickener added is 0.5 to 1.0%, for example, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1.0%, or the like, based on 100% by mass of the total raw milk.

In the present invention, the amount of the humectant is 8 to 20%, for example, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, etc., based on 100% by mass of the raw milk.

Preferably, the skin conditioner comprises the following components in percentage by mass based on 100% of the total mass of the raw milk: 0.01-2.0% of wheat germ extract, 0.5-2.0% of plant anti-allergy agent, 0.5-2.0% of mushroom glucan, 0.05-0.2% of Anxinshu, 0.01-0.3% of Dekouchi, 0.01-0.5% of Terminalia faba fruit extract, 0.01-0.5% of hydrolyzed wheat protein, 0.01-0.5% of wheat ceramide and 0.02-0.06% of antibacterial composition.

In the present invention, the amount of the wheat germ extract added is 0.01 to 2.0%, for example, 0.01%, 0.05%, 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1.0%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0% or the like, based on 100% by mass of the total raw milk.

In the present invention, the amount of the plant anti-allergy agent added is 0.5 to 2.0%, for example, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1.0%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0% or the like, based on 100% by mass of the total raw milk.

In the present invention, the amount of the mushroom glucan to be added is 0.5 to 2.0%, for example, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1.0%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0% or the like, based on 100% by mass of the total raw milk.

In the present invention, the amount of the xinganshu added is 0.05 to 0.2%, for example, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1.0%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0%, or the like, based on 100% by mass of the total raw milk.

In the present invention, the amount of the dermatan added is 0.01 to 0.3%, for example, 0.01%, 0.05%, 0.1%, 0.15%, 0.2%, 0.25%, 0.3% or the like, based on 100% by mass of the total raw milk.

In the present invention, the amount of the terminalia faba fruit extract added is 0.01 to 0.5%, for example, 0.01%, 0.05%, 0.1%, 0.15%, 0.2%, 0.25%, 0.3%, 0.35%, 0.4%, 0.45%, 0.5% or the like, based on 100% by mass of the total raw milk.

In the present invention, the amount of the hydrolyzed wheat protein added may be 0.01 to 0.5%, for example, 0.01%, 0.05%, 0.1%, 0.15%, 0.2%, 0.25%, 0.3%, 0.35%, 0.4%, 0.45%, 0.5% or the like, based on 100% by mass of the total raw milk.

In the present invention, the amount of the wheat ceramide added may be 0.01 to 0.5%, for example, 0.01%, 0.05%, 0.1%, 0.15%, 0.2%, 0.25%, 0.3%, 0.35%, 0.4%, 0.45%, 0.5%, or the like, based on 100% by mass of the total raw milk.

In the present invention, the amount of the antibacterial composition added is 0.02 to 0.06%, for example, 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, or the like, based on 100% by mass of the total raw milk.

Preferably, the plant anti-susceptible agent comprises: centella asiatica extract, polygonum cuspidatum root extract, scutellaria baicalensis root extract, tea leaf extract, glycyrrhiza glabra root extract, chamomile flower extract, and rosemary leaf extract. The combination of the 7 natural plant extracts can synergistically exert the maximum efficacy, has strong anti-inflammatory and soothing effects, can strengthen the skin barrier through immune regulation and soothing, has no primary stimulation, and is helpful for recovering the symptoms of atopic dermatitis.

The terpenoids in the centella asiatica extract can remarkably improve the content of collagen and cell layer fibronectin, stimulate the production of type I collagen which promotes scar maturation, and reduce the generation of inflammatory reaction. In addition, the centella asiatica extract can reduce the production of proinflammatory mediators (IL-1, MMP-1), and improve and repair the barrier function of the skin. The main functional components of resveratrol and emodin in the polygonum cuspidatum root extract have the effects of inhibiting elastase and whitening and diminishing inflammation on skin. The baicalin in the radix scutellariae extract is mainly used for inhibiting activation of sulfhydryl enzyme and preventing degranulation of hypertrophic (basophilic) cells and release of mediators such as histamine and 5-hydroxytryptamine, and has the function of reducing capillary permeability, so that anaphylactic reaction is avoided. The existence of the tea polyphenol in the tea extract can enhance the water locking capacity of the horny layer of the facial skin of a human body, effectively avoid water loss in skin cells and relieve the skin. The mother nucleus of the glycyrrhiza glabra root extract is very similar to isoflavanol in flavonoid compounds, and has a polyphenol structure, so that the glycyrrhiza glabra root extract is named as isoflavanol with phenolic hydroxyl, and has the functions of moistening, moisturizing, diminishing inflammation, astringing, relieving burning pain and helping the skin to restore normal as soon as possible. The chamomile flower extract contains flavonoid compounds, amino acids and other components, can well play a moisturizing effect, regulates the water-oil balance of skin to a certain degree, and has an anti-inflammatory effect. The rosemary leaf extract has good anti-inflammatory activity, and can protect skin, strengthen skin, promote blood circulation and promote skin functions. Meanwhile, the antibacterial and antiviral functions of the rosmarinic acid can inhibit acute infection and chronic infection, have resistance to ultraviolet rays, and can inhibit the degradation of elastin.

Preferably, the antimicrobial composition comprises: herba Agastaches extract (Pogostemon CABLIN), herba Cymbopogonis Citrari extract (Cymbopogon Citratus) and flos Magnoliae extract (Magnolia DENUDATA). The three components are mutually matched and synergized, so that the anti-inflammatory and relieving effects can be further enhanced, the skin barrier can be relieved and strengthened, and the recovery of symptoms of atopic dermatitis is facilitated. The patchouli extract mainly contains patchouli alcohol and patchouli ketone, has good antibacterial activity, and has inhibitory effect on Escherichia coli, Bacillus subtilis, Staphylococcus albus, Tetragenococcus, Staphylococcus aureus, Salmonella, Escherichia coli, Shigella, Staphylococcus aureus, etc. The citronella extract can resist some bacterial and fungi, can prevent some bacterial variation situations, and achieves the effects of clearing damp, relieving itching, eliminating inflammation, removing miliaria and resisting fungi. Meanwhile, the citronella extract also has the functions of moistening skin and regulating grease secretion, and can be added into water to clean the skin and promote blood circulation. The magnolia flower extract contains essential oil as main component, citral, eugenol, phyllanthin and the like, and also contains a small amount of alkaloid, vitamin and flavonoid, and has excellent anti-inflammatory and antiviral effects.

Preferably, panthenol is further included in the skin conditioning agent.

Preferably, the panthenol is added in an amount of 0.05 to 0.5%, for example, 0.05%, 0.06%, 0.08%, 0.1%, 0.12%, 0.14%, 0.16%, 0.18%, 0.2%, 0.22%, 0.24%, 0.26%, 0.28%, 0.3%, 0.35%, 0.4%, 0.45%, 0.5%, or the like, based on 100% by mass of the total raw milk.

Preferably, the fat or oil comprises any one of shea butter, hydrogenated palm kernel oil, caprylic/capric triglyceride, jojoba seed oil, glycerol tri (ethylhexanoate) or polydimethylsiloxane, or a combination of at least two thereof.

Preferably, the emulsifier comprises any one of MON-L, A-165 or wheat emulsifier or a combination of at least two thereof. Wherein. Said MON-L comprises a C14-22 alcohol, a C12-20 alkyl glucoside, and glucose; the A-165 comprises glycerol stearate, glycerol and PEG-100 stearate; the wheat emulsifier comprises cetearyl alcohol cornstalk glycosides and cetearyl alcohol.

Preferably, the thickener comprises xanthan gum and/or EMT-10. Wherein the EMT-10 comprises hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, polysorbate-60 and sorbitan isostearate.

Preferably, the humectant comprises any one or a combination of at least two of glycerol, allantoin, sodium hyaluronate, butanediol, or 1, 2-hexanediol.

Preferably, the raw milk also comprises an antioxidant.

Preferably, the antioxidant is added in an amount of 0.1 to 2.0%, for example, 0.1%, 0.2%, 0.4%, 0.6%, 0.8%, 1%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0%, etc., based on 100% by mass of the total raw milk.

Preferably, the antioxidant comprises tocopherol and/or p-hydroxyacetophenone.

Preferably, the raw milk also comprises an anti-chelating agent.

Preferably, the chelating agent is added in an amount of 0.02 to 0.1%, for example, 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, 0.1%, etc., based on 100% by mass of the total raw milk.

Preferably, the chelating agent is disodium EDTA.

Preferably, the raw milk comprises the following components in percentage by mass: 0.01-2.0% of wheat germ extract, 0.5-2.0% of plant anti-allergy agent, 0.5-2.0% of mushroom glucan, 0.05-0.2% of Anxinshu, 0.01-0.3% of Dekouki, 0.01-0.5% of Terminalia catappa fruit extract, 0.01-0.5% of hydrolyzed wheat protein, 0.01-0.5% of wheat ceramide, 0.02-0.06% of antibacterial composition, 0.05-0.5% of panthenol, 0.5-3.0% of shea butter, 0.5-1.5% of hydrogenated palm kernel oil, 2.0-6.0% of caprylic/capric triglyceride, 0.5-2.5% of Hoffia seed oil, 1.0-6.0% of Triethylhexoate, 0.5-2.5% of polydimethylsiloxane, 1.0-2.5% of MON-L, 0-1650.5-1.5% of A-1.5%, 0.1.5% of emulsifier, 0.03-0.0.0.0% of xanthan gum, 0.5-15.5% of EMT emulsifier, 0.5-0% of xanthan gum, 3.0-10.0% of glycerin, 0.1-0.3% of allantoin, 0.01-0.1% of sodium hyaluronate, 2.0-5.0% of butanediol, 0.4-1.0% of 1, 2-hexanediol, 0.1-1.0% of tocopherol, 0.4-0.6% of p-hydroxyacetophenone, 0.02-0.1% of EDTA disodium and the balance of wheat germ oil.

In a second aspect, the present invention provides a method for preparing a fresh extract raw milk of infant wheat according to the first aspect, wherein the method for preparing the raw milk comprises the following steps:

(1) mixing oil, an emulsifier and a thickener to obtain an oil phase mixed solution; mixing wheat germ oil and humectant with water phase to obtain water phase mixed solution;

(2) adding the oil phase mixed solution obtained in the step (1) into the water phase mixed solution, and homogenizing to obtain emulsion;

(3) and (3) adding a skin conditioner into the emulsion obtained in the step (2), mixing, stirring and filtering to obtain the fresh extract milk of the infant wheat.

Preferably, in the step (1), the temperature of the oil phase mixture is 80 to 85 ℃, for example, 80 ℃, 81 ℃, 82 ℃, 83 ℃, 84 ℃, 85 ℃ and the like.

Preferably, in step (1), the oil phase is mixed for 10-15min, such as 10min, 11min, 12min, 13min, 14min, 15 min.

Preferably, in the step (1), the temperature of the aqueous phase mixing is 85 to 90 ℃, for example, 85 ℃, 86 ℃, 87 ℃, 88 ℃, 89 ℃, 90 ℃ and the like.

Preferably, in step (1), the time for mixing the aqueous phase is 10-15min, such as 10min, 11min, 12min, 13min, 14min, 15 min.

Preferably, in step (2), the temperature for homogenization is 80-82 ℃, for example, 80 ℃, 81 ℃, 82 ℃ and the like can be used.

Preferably, in step (2), the homogenization time is 3-5min, such as 3min, 3.5min, 4min, 4.5min, 5 min.

Preferably, in the step (3), the temperature of the mixing and stirring is 45 ℃ or less, and may be, for example, 10 ℃, 15 ℃, 20 ℃, 25 ℃, 30 ℃, 35 ℃, 40 ℃ or 45 ℃.

Preferably, the preparation method of the raw milk comprises the following steps:

(1) stirring and mixing the grease, the emulsifier, the thickener and the antioxidant at 80-85 ℃ for 10-15min to obtain an oil phase mixed solution; mixing wheat germ oil, humectant and chelating agent at 85-90 deg.C under stirring for 10-15min to obtain water phase mixed solution;

(2) adding the oil phase mixed solution obtained in the step (1) into the water phase mixed solution, and homogenizing at 80-82 ℃ for 3-5min to obtain emulsion;

(3) and (3) cooling the emulsion obtained in the step (2) to below 45 ℃, adding a skin conditioner, mixing, stirring and filtering to obtain the infant wheat fresh extract raw milk.

Compared with the prior art, the invention has the following beneficial effects:

(1) the fresh extract raw milk of the wheat for the infants is safe, mild and non-irritant, is not added with mineral oil and petrolatum, avoids the problem that the mineral oil and petrolatum are difficult to absorb, is not added with preservatives, non-natural pigments and artificial essence, and avoids irritation and sensitivity to skin caused by the substances.

(2) The components of the wheat fresh extract protoplasm milk for the infants are mutually matched, so that the synergistic effect can more effectively relieve the skin pressure, improve the skin barrier capability of the infants, reduce the stimulation caused by the outside, protect the sensitive, tender and fragile skin of the infants, bring safer, better and more effective care to the infants, and have the advantages of easy absorption and long-acting moisture retention.

Detailed Description

The technical solution of the present invention is further explained by the following embodiments. It should be understood by those skilled in the art that the examples are only for the understanding of the present invention and should not be construed as the specific limitations of the present invention.

The components in the following examples were obtained from the following manufacturers: wheat germ extract (Australia source), plant anti-allergy agent (Korea pennisetum), mushroom dextran (Korea pennlandd), indophenmedic (Jade DE jasmine), Defushi (German DE Zhixin), Terminalia faberi fruit extract (Australia source), hydrolyzed wheat protein (German DE Jane), wheat ceramide (German DE Jane), antimicrobial composition (Korea pennsylum); wheat emulsifier (swedish washington); other raw materials are all from common market.

Example 1

The embodiment provides a fresh extract protoplasm milk of infant wheat, which comprises the following components in percentage by mass:

the preparation method of the raw milk provided by the embodiment comprises the following steps:

(1) stirring and mixing the grease, the emulsifier, the thickener and the antioxidant at 82 ℃ for 12min to obtain an oil phase mixed solution; stirring and mixing wheat germ oil, humectant and chelating agent at 86 deg.C for 12min to obtain water phase mixed solution;

(2) adding the oil phase mixed solution obtained in the step (1) into the water phase mixed solution, and homogenizing at 80 ℃ for 4min to obtain emulsion;

(3) and (3) cooling the emulsion obtained in the step (2) to 45 ℃, adding a skin conditioner, mixing, stirring and filtering to obtain the infant wheat fresh extract raw milk.

Example 2

(1) stirring and mixing the grease, the emulsifier, the thickener and the antioxidant at 80 ℃ for 15min to obtain an oil phase mixed solution; stirring and mixing wheat germ oil, humectant and chelating agent at 90 deg.C for 10min to obtain water phase mixed solution;

(2) adding the oil phase mixed solution obtained in the step (1) into the water phase mixed solution, and homogenizing at 82 ℃ for 3min to obtain emulsion;

(3) and (3) cooling the emulsion obtained in the step (2) to 35 ℃, adding a skin conditioner, mixing, stirring and filtering to obtain the fresh extract stock milk of the infant wheat.

Example 3

(1) stirring and mixing the grease, the emulsifier, the thickener and the antioxidant at 85 ℃ for 10min to obtain an oil phase mixed solution; stirring and mixing wheat germ oil, humectant and chelating agent at 85 deg.C for 15min to obtain water phase mixed solution;

(2) adding the oil phase mixed solution obtained in the step (1) into the water phase mixed solution, and homogenizing at 80 ℃ for 5min to obtain emulsion;

(3) and (3) cooling the emulsion obtained in the step (2) to 25 ℃, adding a skin conditioner, mixing, stirring and filtering to obtain the infant wheat fresh extract raw milk.

Example 4

This example provides a wheat fresh extract raw milk for infants, which is different from example 1 in that 0.05% of the antibacterial composition is replaced by a mixture of 0.025% of citronella extract and 0.025% of magnolia extract, and the contents of other components and the preparation method are the same as example 1.

Example 5

This example provides a wheat fresh extract milk for infants, which is different from example 1 in that 0.05% of the antibacterial composition is replaced by a mixture of 0.025% of pogostemon cablin extract and 0.025% of citronella grass extract, and the contents of other components and preparation method are the same as example 1.

Example 6

Example 7

The present example provides a fresh extract raw milk of infant wheat, which is different from example 1 in that the fat is not added with shea butter, the content of jojoba seed oil is increased to 4.0%, and the content of other components and the preparation method are the same as example 1.

Example 8

The present example provides a fresh extract raw milk of infant wheat, which is different from example 1 in that jojoba seed oil is not added to the oil, the content of shea butter is increased to 4.0%, and the content of other components and the preparation method are the same as example 1.

Example 9

The present example provides a baby wheat fresh extract raw milk, which is different from example 1 in that allantoin is not added to the moisturizer, the content of sodium hyaluronate is increased to 0.28%, and the content of other components and the preparation method are the same as example 1.

Example 10

The present example provides a baby wheat fresh extract raw milk, which is different from example 1 in that sodium hyaluronate is not added to the moisturizer, the allantoin content is increased to 0.28%, and the other component contents and the preparation method are the same as example 1.

Comparative example 1

The comparative example provides a fresh extract stock milk of baby wheat, which is different from example 1 in that the skin conditioner is not added with wheat germ extract, the content of the composite plant anti-allergy agent is increased to 1.063%, the content of mushroom glucan is increased to 2.062%, the content of phenytoin is increased to 0.163%, the content of dermaphyllum is increased to 0.162%, the content of terminalia faba fruit extract is increased to 0.163%, the content of hydrolyzed wheat protein is 0.072%, the content of wheat ceramide is increased to 0.163%, the content of the antibacterial composition is increased to 0.112%, and the content of other components and the preparation method are the same as example 1.

Comparative example 2

The comparative example provides a fresh extract stock milk of baby wheat, which is different from the example 1 in that the skin conditioner is not added with a compound plant anti-allergy agent, the content of wheat germ extract is increased to 0.63%, the content of mushroom glucan is increased to 2.12%, the content of phenytoin is increased to 0.23%, the content of dermatan is increased to 0.22%, the content of terminalia faba fruit extract is increased to 0.23%, the content of hydrolyzed wheat protein is increased to 0.13%, the content of wheat ceramide is increased to 0.23%, the content of an antibacterial composition is increased to 0.17%, and the content of other components and the preparation method are the same as the example 1.

Comparative example 3

The present comparative example provides a baby wheat fresh extract raw milk, which is different from example 1 in that the skin conditioner is not added with mushroom glucan, the content of wheat germ extract is increased to 0.75%, the content of composite plant anti-allergy agent is increased to 1.25%, the content of phenytoin is increased to 0.35%, the content of dermatan is increased to 0.35%, the content of terminalia faba fruit extract is increased to 0.35%, the content of hydrolyzed wheat protein is increased to 0.26%, the content of wheat ceramide is increased to 0.35%, the content of antibacterial composition is increased to 0.3%, and the content of other components and the preparation method are the same as example 1.

Comparative example 4

The present comparative example provides a fresh extract raw milk of wheat for infants, which is different from example 1 in that the skin conditioner is not added with indomethacin, the content of wheat germ extract is increased to 0.513%, the content of composite plant anti-allergy agent is increased to 1.012%, the content of mushroom glucan is increased to 2.013%, the content of dermatan is increased to 0.112%, the content of terminalia faba fruit extract is increased to 0.113%, the content of hydrolyzed wheat protein is increased to 0.022%, the content of wheat ceramide is increased to 0.113%, the content of antibacterial composition is increased to 0.062%, and the content of other components and the preparation method are the same as example 1.

Comparative example 5

The present comparative example provides a fresh extract raw milk of wheat for infants, which is different from example 1 in that the skin conditioner is not added with dermatan, the content of wheat germ extract is increased to 0.513%, the content of composite plant anti-allergy agent is increased to 1.012%, the content of mushroom glucan is increased to 2.013%, the content of phenytoin is increased to 0.112%, the content of terminalia faba fruit extract is increased to 0.113%, the content of hydrolyzed wheat protein is increased to 0.022%, the content of wheat ceramide is increased to 0.113%, the content of antibacterial composition is increased to 0.062%, and the content of other components and the preparation method are the same as example 1.

Comparative example 6

The present comparative example provides a fresh extract raw milk of wheat for infants, which is different from example 1 in that the skin conditioner is not added with terminalia faba fruit extract, the content of wheat germ extract is increased to 0.513%, the content of composite plant anti-allergy agent is increased to 1.012%, the content of mushroom glucan is increased to 2.013%, the content of phenytoin is increased to 0.112%, the content of dermatan is increased to 0.113%, the content of hydrolyzed wheat protein is increased to 0.022%, the content of wheat ceramide is increased to 0.113%, the content of antibacterial composition is increased to 0.062%, and the content of other components and the preparation method are the same as example 1.

Comparative example 7

The comparison example provides a fresh extract raw milk of baby wheat, which is different from the milk in example 1 in that the skin conditioner is not added with hydrolyzed wheat protein, the content of wheat ceramide is increased to 0.11%, and the content of other components and the preparation method are the same as those in example 1.

Comparative example 8

The present comparative example provides a wheat fresh extract raw milk for infants, which is different from example 1 in that the skin conditioner is not added with an antibacterial composition, the content of wheat germ extract is increased to 0.51%, the content of composite plant anti-allergy agent is increased to 1.01%, the content of mushroom glucan is increased to 2.01%, the content of phentonate is increased to 0.11%, the content of dermatan is increased to 0.11%, the content of terminalia faba fruit extract is increased to 0.11%, the content of hydrolyzed wheat protein is increased to 0.016%, the content of wheat ceramide is increased to 0.11%, and the content of other components and the preparation method are the same as example 1.

Comparative example 9

The comparison example provides a fresh extract raw milk of baby wheat, which is different from the milk of example 1 in that the wheat germ oil is replaced by deionized water, and the contents of other components and the preparation method are the same as those of example 1.

Test example 1

Patch test

Randomly selecting 30 children of 2-5 years old, including 12 boys and 18 girls, and the test substances were infant wheat fresh extract raw milk prepared in examples 1-17 and infant wheat fresh extract raw milk prepared in comparative examples 1-9. The negative control was a blank control. In the closed spot test method, about 0.02g of the test substance is coated in a spot device, an external medical adhesive tape is pasted on the bent side of the forearm of the testee, the test substance is removed within 24h, the skin reaction is observed within 0.5h, 24h and 48h of the spot test respectively, the skin reaction grading standard in the cosmetic hygiene specification (2015 edition) is shown in table 1, and the test result is shown in table 2.

TABLE 1

Grade	Symbol	Identification criteria
			0	-	Negative reaction: has no irritation and erythema
1	±	And (3) suspicious reaction: mild erythema
			2	+	Weak positive reaction: erythema
3	++	Strong positive reaction: erythema, papules, blisters
			4	+++	Extremely strong positive reaction: severe edema and blisters

TABLE 2

The skin patch test results in table 2 show that the baby wheat fresh extract raw milk of the invention has no irritation and no erythema, and compared with comparative examples 1-8, the baby wheat fresh extract raw milk of the invention has somewhat reduced effect, because the components in the skin conditioner are matched with each other, so that the skin irritation can be further relieved, and the skin tolerance can be enhanced. The lack of either component proved to be insufficient for the desired regulation. Meanwhile, the components in the composition and the cosmetics provided by the invention are safe, mild and non-irritant. The raw milk provided by the invention is scientific and reasonable in compatibility, can obviously reduce toxic and side effects and irritation after synergistic interaction, and can be proved to cause no adverse reaction on children skin.

Test example 2

Stability test

The test substance is the fresh extract raw milk of the infant wheat prepared in the examples 1-8, the raw milk of the example 1 is sampled according to the national standard of GBT 34857-. Specific test results are shown in table 3.

TABLE 3

Sample name	Traits	Stability of
			Example 1	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
Example 2	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
			Example 3	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
Example 4	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
			Example 5	Milky white emulsion, uniformNo particles and natural light smell	The above-mentioned problems do not occur, and the stability is good
Example 6	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
			Example 7	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
Example 8	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
			Example 9	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
Example 10	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
			Example 11	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
Example 12	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
			Example 13	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
Example 14	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
			Example 15	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
Example 16	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good
			Example 17	Milky white emulsion, uniform and no particles, and natural and light smell	The above-mentioned problems do not occur, and the stability is good

The above test results show that: the fresh extract raw milk of the infant wheat prepared in the examples 1 to 8 is milky emulsion, uniform, free of particles, natural and light in smell, free of undesirable phenomena such as bleeding, layering, separation, precipitation, discoloration, peculiar smell and emulsion breaking and good in stability, and can pass a high-temperature and low-temperature stability experiment.

Test example 3

Skin barrier function test

The test evaluation is carried out on 75 healthy testers with no allergic history of skin of 5-12 years old in batches, and the lower the TEWL value of the skin, the larger the reduced change rate, which indicates that the barrier function for preventing water loss is stronger.

The rate of change of TEWL values was:

TEWL change rate ═ (measured value-blank control value)/blank control value · 100%

Using equipment

Dual MPA 580, Probe Tewameter TM300, was tested by a skin moisture loss tester. 3cm of each forearm of the subject²The area of the size is a test area, and the test area of the arm should be cleaned with clear water and sit still in a constant temperature independent environment (22 +/-1 ℃) and an environment with the relative humidity of 50 +/-5% for 30-60 minutes before the test of the subject. Then using a pipette at 2.0mg sample/cm²The sample was uniformly smeared in the test area with latex gloves, initial value blank control values, 5min, 2h, 4h TEWL values were measured, and 4h TEWL change rate was calculated, and the results are shown in table 4 below:

TABLE 4

The experimental results in table 4 show that the change rate of the hydration degree of the fresh extracted raw milk of baby wheat prepared in examples 1-17 of the present invention is reduced by more than-45% at the 4 th hour, and as an optimal technical scheme of the present invention, the change rate of the hydration degree of the fresh extracted raw milk of baby wheat prepared in examples 1-3 is reduced by more than-69% at the 4 th hour, which indicates that the compatibility of the components of the fresh extracted raw milk of baby wheat of the present invention is scientific and reasonable, and synergistic.

Test example 4

Product efficacy testing

Considering that the infants are small in age and cannot clearly express self experience, and the mothers can choose skin care products for the children and then decide to buy the skin care products for the children without any stimulation after the skin care products are tried out by the mothers. 60 adults with slightly sensitive facial skin were selected and divided into 3 groups for experience, 21 men and 39 women, both aged 20-35 years, were continuously administered the lotions obtained in examples 1-3 of the present invention for 3 days, and the testers were unable to use any skin care products such as lotions and creams within 24 hours before the baby wheat fresh extract raw milk prepared in examples 1-17 of the present invention and comparative examples 1-9 was administered.

The specific test results are shown in table 5:

TABLE 5

Sample name	Slight greasiness	Insufficient moisture retention and moistening	Just and comfortable	Redness and itching
					Example 1	0	1	19	0
Example 2	0	7	13	0
					Example 3	5	0	15	0
Example 4	6	0	14	0
					Example 5	6	0	13	0
Example 6	5	0	14	0
					Example 7	5	1	14	0
Example 8	4	0	16	0
					Example 9	2	5	13	0
Example 10	3	1	16	0
					Example 11	1	3	16	0
Example 12	0	5	15	0
					Example 13	2	6	12	0
Example 14	3	5	12	0
					Example 15	1	5	14	0
Example 16	3	6	11	0
					Example 17	5	5	10	0
Comparative example 1	5	10	5	0
					Comparative example 2	6	8	6	0
Comparative example 3	7	5	8	0
					Comparative example 4	6	7	6	1
Comparative example 5	3	12	5	0
					Comparative example 6	4	9	7	0
Comparative example 7	5	6	8	1
					Comparative example 8	5	6	8	1
Comparative example 9	5	9	4	2

As can be seen from the test data in table 5, the infant wheat fresh extract raw milk product prepared in examples 1 to 8 of the present invention has no adverse reactions, i.e., no irritation, such as redness, stinging, itching, etc., after being used in the efficacy test. And the trial feel is fresh and cool, is not greasy, and is moisturizing and moist. And when any component in the skin conditioner is determined by the raw milk products provided by the comparative examples 1-8, the relieving speed is slow, the effect is poor, more people feel slightly greasy, the moisture retention and moistening are insufficient, and even the problems of slight redness and itching appear in severe people. The fresh extract protoplasm milk of the baby wheat disclosed by the invention has high-efficiency and allergy-relieving components, and the components are matched with each other and have synergistic interaction, so that the barrier capability of the skin of the baby can be improved, the colony balance of the skin of the baby is adjusted, the anti-inflammatory and anti-irritation capabilities of the skin are enhanced, and the fresh extract protoplasm milk of the baby wheat has a relatively obvious effect on the improvement of the skin.

The applicant states that the present invention is described by the above examples to describe the baby wheat fresh extract puree milk and the preparation method thereof, but the present invention is not limited to the above examples, i.e. it does not mean that the present invention is implemented only by relying on the above examples. It should be understood by those skilled in the art that any modification of the present invention, equivalent substitutions of the raw materials of the product of the present invention, addition of auxiliary components, selection of specific modes, etc., are within the scope and disclosure of the present invention.

Claims

1. An infant wheat freshly extracted raw milk, comprising: wheat germ oil, a skin conditioner, grease, an emulsifier, a thickener and a humectant;

2. The infant wheat freshly extracted raw milk according to claim 1, wherein the raw milk comprises, by mass: 5-25% of grease, 1-10% of skin conditioner, 0.5-5.0% of emulsifier, 0.5-1.0% of thickener, 8-20% of humectant and the balance of wheat germ oil.

3. The infant wheat freshly extracted raw milk according to claim 1 or 2, wherein the skin conditioner comprises, based on 100% of the total mass of the raw milk: 0.01-2.0% of wheat germ extract, 0.5-2.0% of compound plant anti-allergy agent, 0.5-2.0% of mushroom glucan, 0.05-0.2% of Anxinshu, 0.01-0.3% of Dekouchi, 0.01-0.5% of Terminalia faba fruit extract, 0.01-0.5% of hydrolyzed wheat protein, 0.01-0.5% of wheat ceramide and 0.02-0.06% of antibacterial composition.

4. The infant wheat fresh extract stock milk according to any one of claims 1 to 3, wherein the complex plant anti-allergy agent comprises: centella asiatica extract, polygonum cuspidatum root extract, scutellaria baicalensis root extract, tea leaf extract, glycyrrhiza glabra root extract, chamomile flower extract, and rosemary leaf extract;

preferably, the antimicrobial composition comprises: patchouli extract, citronella extract, and magnolia extract;

preferably, panthenol is further included in the skin conditioning agent;

preferably, the adding amount of the panthenol is 0.05-0.5% based on the total mass of the raw milk as 100%.

5. The infant wheat fresh extract stock milk according to any one of claims 1 to 4, wherein the oil comprises any one or a combination of at least two of shea butter, hydrogenated palm kernel oil, caprylic/capric triglyceride, jojoba seed oil, tri (ethyl hexanoate) glyceride, or polydimethylsiloxane;

preferably, the emulsifier comprises any one of MON-L, A-165 or wheat emulsifier or a combination of at least two thereof;

preferably, the thickener comprises xanthan gum and/or EMT-10;

6. The baby wheat freshly extracted raw milk according to any one of claims 1-5, further comprising an antioxidant;

preferably, the addition amount of the antioxidant is 0.1-2.0% based on the total mass of the raw milk as 100%;

preferably, the antioxidant comprises tocopherol and/or p-hydroxyacetophenone;

preferably, the raw milk also comprises an anti-chelating agent;

preferably, the addition amount of the chelating agent is 0.02-0.1% based on the total mass of the raw milk as 100%;

preferably, the chelating agent is disodium EDTA.

7. The infant wheat freshly extracted raw milk according to any one of claims 1-6, wherein the raw milk comprises, in mass percent: 0.01-2.0% of wheat germ extract, 0.5-2.0% of plant anti-allergy agent, 0.5-2.0% of mushroom glucan, 0.05-0.2% of Anxinshu, 0.01-0.3% of Dekouki, 0.01-0.5% of Terminalia catappa fruit extract, 0.01-0.5% of hydrolyzed wheat protein, 0.01-0.5% of wheat ceramide, 0.02-0.06% of antibacterial composition, 0.05-0.5% of panthenol, 0.5-3.0% of shea butter, 0.5-1.5% of hydrogenated palm kernel oil, 2.0-6.0% of caprylic/capric triglyceride, 0.5-2.5% of Hoffia seed oil, 1.0-6.0% of Triethylhexoate, 0.5-2.5% of polydimethylsiloxane, 1.0-2.5% of MON-L, 0-1650.5-1.5% of A-1.5%, 0.1.5% of emulsifier, 0.03-0.0.0.0% of xanthan gum, 0.5-15.5% of EMT emulsifier, 0.5-0% of xanthan gum, 3.0-10.0% of glycerin, 0.1-0.3% of allantoin, 0.01-0.1% of sodium hyaluronate, 2.0-5.0% of butanediol, 0.4-1.0% of 1, 2-hexanediol, 0.1-1.0% of tocopherol, 0.4-0.6% of p-hydroxyacetophenone, 0.02-0.1% of EDTA disodium and the balance of wheat germ oil.

8. The method of producing infant wheat freshly extracted raw milk according to any one of claims 1-7, wherein the method of producing raw milk comprises the steps of:

9. The method for preparing the oil-phase mixture of claim 8, wherein the temperature for mixing the oil phase in step (1) is 80-85 ℃;

preferably, in the step (1), the oil phase is mixed for 10-15 min;

preferably, in the step (1), the temperature for mixing the water phase is 85-90 ℃;

preferably, in the step (1), the time for mixing the water phase is 10-15 min;

preferably, in the step (2), the temperature of the homogenization is 80-82 ℃;

preferably, in the step (2), the homogenization time is 3-5 min;

preferably, in the step (3), the temperature of the mixing and stirring is 45 ℃ or lower.

10. The method of claim 9, wherein the raw milk is prepared by the steps of: