CN111437234A - Baby hip protection cream - Google Patents

Abstract

The invention relates to an infant buttocks-care cream, which relates to the technical field of skin care products and comprises water, an emulsifier, grease, a thickening stabilizer, antiseptic components and functional components, wherein the emulsifier comprises cetearyl alcohol olive oleate and sorbitan olive oleate, the grease comprises shea butter fruit resin extract, the thickening stabilizer comprises beeswax and xanthan gum, the antiseptic components comprise 1.2 pentanediol and p-hydroxyacetophenone, and the functional components comprise bisabolol, ginger extract, N-palmitoyl hydroxyproline whale wax ester, β -glucan and allantoin.

Description

Baby hip protection cream

Technical Field

The invention relates to the technical field of skin care products, in particular to infant hip cream.

Background

The red buttocks of babies are also called diaper rash or diaper rash in medicine. Diaper rash also occurs due to a plurality of factors, such as thin cuticle of skin of a baby, more moisture and chloride in endothelium and easy allergy; the natural sebum protective film of the skin is damaged by stimulation such as frequent milk overflow, urine, paper diaper friction and the like; the hip skin is moist for a long time, the diaper is not breathable when being worn, and a large amount of germs are easy to breed on the surface of the skin when the diaper is used for a long time; the hip skin is often contacted with some cleaning solutions, the original beneficial flora balance of the skin of the baby is broken, and the protective effect of the skin mucosa is damaged due to flora disorder.

In the market, hot-market infant hip cream brands such as Sudocrem UK fart cream, Beijing, ganick, Miaosile, Lu' an-fit products and the like all contain zinc oxide components, and although zinc oxide can effectively prevent water, isolate, astringe the skin and prolong the effective bacteriostasis time, more and more researches show that zinc oxide particles have the characteristics of moisture absorption and astringency, the zinc oxide particles can slightly dehydrate the skin and are not suitable for frequent use; and the effect is that the protective film is formed on the surface of the skin, only the red butt can be relieved, the symptoms and root causes are treated, and the effectiveness is slightly poor.

In addition, because conventional cream emulsions require the addition of conventional preservatives for their shelf life, there is a clear specification in the cosmetic safety specifications (2015 edition) which are acceptable preservatives for cosmetic use, such as: the traditional preservatives can cause more or less potential harm to the skin in the long-term use process of the skin, and some preservatives are gradually forbidden even in the European Union.

In order to improve the safety of the product, the development of baby skin care products with lower irritation, better anti-inflammatory and antibacterial effects and higher safety is needed.

Disclosure of Invention

In view of the above, the technical problem to be solved by the present invention is to provide a baby hip cream, which does not contain zinc oxide substance, does not contain traditional antiseptic, has more natural components, and has better and safer anti-inflammatory and antibacterial effects.

In order to solve the technical problems, the invention adopts the following technical scheme:

a baby hip cream comprises water, emulsifier, oil, thickening stabilizer, antiseptic component, and effective component,

the emulsifier is olive oil emulsifier from Italy B & T company, the olive oil is grease similar to human sebum, the emulsion forms lamellar liquid crystal structure, is easily absorbed by skin, and shows excellent absorbability of active ingredients, and specifically comprises cetearyl olive oleate and sorbitan olive oleate.

The grease adopts vegetable grease, and is specially selected from a shea butter extract with anti-inflammatory and skin repair functions, and is sourced from AAK (American Association of Kiwi berry) manufacturers in the world;

the thickening stabilizer adopts the matching of beeswax and xanthan gum;

the preservative component is prepared by matching 1.2 pentanediol and p-hydroxyacetophenone, is very safe and mild, and has broad-spectrum antibacterial property;

the functional components are reasonable in matching, the inflammation is well inhibited by selecting the matching of bisabolol and ginger root, the skin barrier is reconstructed by selecting cetyl N-palmitoyl hydroxyproline to increase the tolerance of tender skin of a baby, particularly the fragile skin of the anus, β -glucan is selected and extracted from oat and compounded with allantoin, the healing of wounds of the fragile skin of the anus or the hip can be promoted, and the tender skin of the baby is protected in multiple mechanisms.

An infant hip cream comprises the following components in percentage by weight:

1-5% of cetearyl olive oleate (CETEARY L O L IVATE), 1-5% of SORBITAN olive oleate (SORBITAN O L IVATE), 10-20% of shea butter, 0.5-1.5% of shea butter extract, 1-3% of beeswax, 0.1-0.3% of xanthan gum, 2-6% of 1, 2-pentanediol, 0.3-0.8% of p-hydroxyacetophenone, 0.01-0.08% of bisabolol, 0.05-0.15% of ginger extract, 0.1-0.5% of cetyl palmitate hydroxyproline, 0.3-0.8% of β -glucan, 0.1-0.3% of allantoin and the balance of water.

Preferably, the infant hip cream of the present invention comprises the following components by weight:

cetearyl alcohol olive oleate 3%, sorbitan olive oleate 3%, shea butter 16%, shea butter extract 1%, beeswax 2%, xanthan gum 0.2%, 1, 2-pentanediol 4%, p-hydroxyacetophenone 0.5%, bisabolol 0.05%, ginger extract 0.1%, N-palmitoyl hydroxyproline cetyl ester 0.3%, β -dextran 0.5%, allantoin 0.2%, and balance water.

Furthermore, the infant hip cream also comprises 0.3-0.8% of hexyldecanol, 0.05-0.15% of stearic acid and 0.05-0.15% of rape sterol, and the three components form a skin composite repair system.

The ratio of hexyldecanol to stearic acid in the infant hip cream of the present invention is preferably 0.5%, the ratio of stearic acid is preferably 0.1%, and the ratio of campesterol is preferably 0.1%.

Furthermore, the infant hip cream provided by the invention also comprises 0.05-0.15% of tocopherol (vitamin E) which is used as an antioxidant to maintain the stability of vegetable oil.

The content of tocopherol (vitamin E) in the infant hip cream of the present invention is preferably 0.1%.

Further, the ginger extract in the present invention is a ginger root extract.

According to the invention, the beewax and the xanthan gum are matched to serve as a thickening stable combination, the beewax and the xanthan gum have excellent safety performance when used, 1.2 pentanediol and p-hydroxyacetophenone serve as antiseptic volumes, the product is safe and mild, and has broad-spectrum antibacterial properties, the functional components play roles in resisting inflammation, reconstructing a skin barrier and promoting wound healing, the combination of bisabolol and ginger root can well inhibit inflammation, the N-palmitoyl hydroxyproline whale wax ester reconstructs the skin barrier to increase the tolerance of tender skin of a baby, particularly the fragile skin of the anus edge, β -glucan is a component extracted from oat and is compounded with allantoin, the healing of the damaged skin of the anus edge or the hip can be promoted, and the functional components protect the tender skin of the baby in multiple mechanisms.

P-hydroxyacetophenone is a plant source, is particularly mild, is evaluated as the lowest risk of '1' by beauty-repair APP, exists in L ampaya hieronymi (herbal medicine, native to Latin America) and Rubus chamaemorus (cloudberry grown in Gaoshan), has the functions of preventing oxidation, increasing tolerance, stabilizing emulsion and broad preservation, has better water solubility, solves the defect that a plurality of preservatives or preservative substitute products are not easy to add, has the functions of resisting irritation and being a preservative substitute product, is singly used, needs to be added by more than 1 percent to have certain broad spectrum, and has broad-spectrum antibacterial performance at the addition of 0.5 to 0.8 percent if matched with pentanediol.

In the invention, a compound system which replaces zinc oxide and other components with stimulating functions in the traditional hip cream is adopted: shea butter, shea butter extract, repair composite system (N-palmitoyl hydroxyproline cetyl esters, hexyldecanol, stearic acid, brassinosteroids) + xinminshu (bisabolol + ginger root) + allantoin.

1. The shea butter, commonly known as shea butter, is oil extracted from a plant in Africa, has the functions of resisting inflammation, repairing and moistening skin, and has a certain isolation effect;

2. shea butter extract: the shea butter extract with biological activity is in the form of thick and yellow oily gel, contains Triterpene ester (Triterpen), can increase epidermal barrier, protect skin against aging, protect skin against environmental stress, and jointly expresses the functions of repairing skin and resisting inflammation; triterpenes can repair skin problems caused by chemical stress, ultraviolet radiation or municipal pollution;

3. repairing the composite system: the composition of cetyl N-palmitoyl hydroxyproline, hexyldecanol, stearic acid and campesterol can rebuild skin barrier and repair skin, and has anti-inflammatory effect;

4. the material shows that the alpha-bisabolol can reduce the release of leukotriene L TB4 and interleukin 1L-1 a caused by PMA, and simultaneously inhibit the generation of calcium ion mediated interleukin 1L-1 a, but has no inhibiting effect on PGE 2. experiments prove that the ginger root extract can effectively inhibit the synthesis of inflammatory mediator TNF-a, but has no effect on I L-1 a, the two are compounded to form a composite anti-stimulation component with synergistic effect, in vitro experiments prove that the composition has high-efficiency anti-inflammatory and ultraviolet radiation erythema fading effects, and human experiments prove that the composition has synergistic skin anti-stimulation effect;

5.β -dextran + allantoin has effect in promoting wound healing.

The invention can replace zinc oxide by the 5 combinations, and the components are safe and mild from the raw material. Therefore, the zinc oxide can be abandoned from the components of the infant hip cream, and the equivalent effect can still be achieved.

The components of the invention, of which more than 90% are derived from natural sources, include emulsifiers derived from olive extract components; and the safety risk level of all the components is the highest level; the present invention is defined by the FDA and does not identify any risk substances.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

An infant hip cream comprises the following components in percentage by weight:

10% shea butter, 2% 1, 2-pentanediol, 1% cetearyl olive oleate, 1% sorbitan olive oleate, 1% beeswax, 0.5% shea butter extract, 0.3% β -dextran, 0.3% hexyldecanol, 0.01% bisabolol, 0.1% cetyl hydroxyproline N-palmitoyl cetyl wax ester, 0.05% stearic acid, 0.05% brassinosteroids, 0.3% p-hydroxyacetophenone, 0.1% allantoin, 0.1% xanthan gum, 0.05% ginger extract, 0.05% tocopherol, and the balance water.

Example 2

An infant hip cream comprises the following components in percentage by weight:

16% shea butter, 4% 1, 2-pentanediol, 3% cetearyl olive oleate, 3% sorbitan olive oleate, 2% beeswax, 1% shea butter extract, 0.5% β -dextran, 0.5% hexyldecanol, 0.05% bisabolol, 0.3% cetyl hydroxyproline N-palmitoyl cetyl wax ester, 0.1% stearic acid, 0.1% brassinol, 0.5% p-hydroxyacetophenone, 0.2% allantoin, 0.2% xanthan gum, 0.1% ginger extract, 0.1% tocopherol, and the balance water.

Example 3

An infant hip cream comprises the following components in percentage by weight:

20% shea butter, 6% 1, 2-pentanediol, 5% cetearyl olive oleate, 5% sorbitan olive oleate, 3% beeswax, 1.5% shea butter extract, 0.8% β -dextran, 0.8% hexyldecanol, 0.08% bisabolol, 0.5% cetyl hydroxyproline N-palmitoyl cetyl wax ester, 0.15% stearic acid, 0.15% brassinosteroids, 0.8% p-hydroxyacetophenone, 0.3% allantoin, 0.3% xanthan gum, 0.15% ginger extract, 0.15% tocopherol, and the balance water.

The invention is examined for the product of example 2.

The examination method comprises the following steps: the samples were placed in corresponding thermostats, taken out every 30 days, returned to room temperature and examined by smearing, visual inspection, olfaction, sampling and testing, and the results are shown in table 1.

Table 1 product review table of example 2

As can be seen from Table 1, the samples have excellent antibacterial effect, the pH value of the product is stable under the condition of 38-45 ℃ for 90 days, and the color, the smell and the appearance can be kept in good states, which indicates that the hip cream can keep the requirements of the product on no change of the properties for 90 days without the traditional preservative and natural components, and the antibacterial effect is still excellent.

Clinical trial effect

200 red hip children are selected from pediatric wards of children hospitals in Hangzhou city, the children are aged 1-12 months and randomly divided into a control group and an observation group, each group comprises 100 people, wherein each half of the children are male and female, and the children are treated as follows:

(1) the hip cream of example 2 was tested on 100 infants with red buttocks, after each stool, the infants were immediately washed with warm water and wiped dry, and then a layer of hip cream was applied with a sterile cotton swab;

(2) after each defecation, the control group is cleaned by warm water and wiped dry without coating hip cream;

the healing of two groups of red hip infants was counted daily during one week, and the results are shown in table 2.

TABLE 2 healing of two groups of infants with red buttocks in one week

As can be seen from table 2, in the observation group, the cure rate of the hip cream of the present invention can reach 6% on day 1, and as time goes on, the cure rate increases at a rate of more than 10 cases/day from day 3, and reaches 98 cases on day 7, and the cure rate reaches 98%. In the control group, the cure rate was 0 on both day 1 and day 2, and the infant patients who had healed with red buttocks began to appear on the third day, and the cure rate was 38 by day 7. The hip cream has the advantages of obvious effect, quick response, high cure rate and basically response to the skin of a high-sensitivity infant within one week. The compound system of the shea butter, the shea butter extract and the compound repair system (hexyldecanol, stearic acid and campestris sterols), the anabasine (bisabolol, ginger root) and the allantoin can quickly generate an effect on the surface of the skin, can perform the effects of isolation protection, inflammation diminishing and bacteriostasis on the red buttocks, can replace the irritant components such as zinc oxide in the existing hip cream, and can play the effects of quick effect taking and high cure rate under the condition that the components are natural and the traditional preservative is not used.

Product use investigation results

The hip cream of example 2 of the present invention was used on 14 babies as shown in Table 3 below.

TABLE 3 comparison of baby's use of the invention with other brand hip-pads

As can be seen from Table 3, the hip cream provided by the invention can quickly cure red buttocks of babies regardless of sensitive skin with red buttocks or skin with red buttocks not easy to be red, and does not generate reactions such as allergy and the like because the natural components of the product are high and no irritant components such as zinc oxide and the like are contained. Compared with other common hip cream brands, the hip cream does not contain the traditional zinc oxide component, but has excellent absorption and isolation effects and can be satisfied by parents of babies, and the hip cream is a compound system which can replace zinc oxide and has good isolation and anti-inflammation effects.

It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And any modifications, equivalents, improvements and the like which are obvious and which are made by this disclosure are intended to be included within the scope of the present invention.

Claims (8)

1. An infant hip cream is characterized by comprising an emulsifier, grease, a thickening stabilizer, an antiseptic component, an effective component and water, wherein,

the emulsifier comprises cetearyl olive oleate and sorbitan olive oleate;

the oil comprises shea butter and shea butter extract;

the thickening stabilizer comprises beeswax and xanthan gum;

the preservative component comprises 1.2 pentanediol and p-hydroxyacetophenone;

the effective components comprise bisabolol, ginger extract, cetyl N-palmitoyl hydroxyproline, β -dextran, and allantoin.

2. The infant hip cream according to claim 1, characterized by comprising the following components in percentage by mass:

1-5% of cetearyl alcohol olive oleate, 1-5% of sorbitan olive oleate, 10-20% of shea butter, 0.5-1.5% of shea butter extract, 1-3% of beeswax, 0.1-0.3% of xanthan gum, 2-6% of 1, 2-pentanediol, 0.3-0.8% of p-hydroxyacetophenone, 0.01-0.08% of bisabolol, 0.05-0.15% of ginger extract, 0.1-0.5% of N-palmitoyl hydroxyproline cetyl wax ester, 0.3-0.8% of β -glucan, 0.1-0.3% of allantoin and the balance of water.

3. The infant hip cream according to claim 2, characterized by comprising the following components in percentage by mass:

cetearyl alcohol olive oleate 3%, sorbitan olive oleate 3%, shea butter 16%, shea butter extract 1%, beeswax 2%, xanthan gum 0.2%, 1, 2-pentanediol 4%, p-hydroxyacetophenone 0.5%, bisabolol 0.05%, ginger extract 0.1%, N-palmitoyl hydroxyproline cetyl ester 0.3%, β -dextran 0.5%, allantoin 0.2%, and balance water.

4. The infant hip cream according to claim 2 or 3, further comprising hexyldecanol 0.3-0.8%, stearic acid 0.05-0.15%, campesterol 0.05-0.15%.

5. The infant hip cream according to claim 4, characterized in that said ratio of hexyldecanol is 0.5%, stearic acid is 0.1%, campesterol is 0.1%.

6. The infant hip cream according to claim 2 or 3, further comprising 0.05-0.15% of tocopherol.

7. The infant hip cream according to claim 6, characterized in that the content of tocopherol is 0.1%.

8. The infant hip cream according to claim 2 or 3, wherein the ginger extract is a ginger root extract.