CN105816848A - Protective cream capable of dispelling dampness and preparation method thereof - Google Patents
Protective cream capable of dispelling dampness and preparation method thereof Download PDFInfo
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- CN105816848A CN105816848A CN201510004976.0A CN201510004976A CN105816848A CN 105816848 A CN105816848 A CN 105816848A CN 201510004976 A CN201510004976 A CN 201510004976A CN 105816848 A CN105816848 A CN 105816848A
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Abstract
The invention discloses a protective cream capable of dispelling dampness. The protective cream comprises the following components: water, butanediol, glycerin, hydrogenated polybutene, meadowfoam seed oil, sorbitan isostearate, polydimethylsiloxane, wheat germ oil, disteardimonium hectorite, tocopheryl acetate, a Chinese gall extract product, hydrogenated phosphatidylcholine, beta-glucan, bisabolol, N-palmitoyl hydroxyproline spermaceti wax ester, hexyldecanol, brassinosteroids, a calendula extract product, a purslane extract product, hydrolyzed rice protein, a ginger root extract product, dipotassium glycyrrhizinate, hydrogenated acetate, benzyl alcohol, and disodium EDTA. The invention provides the protective cream which is healthier to a user and can protect skin when eczema is treated, and the invention also provides the preparation method thereof.
Description
Technical field
The present invention relates to a kind of ointment, more specifically, it relates to a kind of ointment protecting eczema.
Background technology
Eczema is a kind of scytitis reaction of the acute pruritus caused by multiple internal and external factor.Divide three phases acute, subacute, chronic.Acute stage tool oozes out tendency, and chronic phase then infiltrates, plump.Some patient directly translates into chronic eczema.Skin lesion has the features such as pleomorphism, symmetry, pruritus and easy recurrent exerbation.
Eczema is commonplace anaphylaxis dermatosis in infant period, and recurrent erythra usually annoyings father and mother.After baby suffers from eczema, often twisting head goes friction or is held by hand scratching, then occur distributing, the red papules of the small rice grain sample of cluster or erythema, have gradually becomes phlysis, merge in flakes, very itch, after vesicle ulceration, have yellow slurry to ooze out, incrustation finally occurs, about about 2 to 3 weeks of manager.Often recurrent exerbation, time light time weight.Trunk and extremity can be involved time serious, including pudendum and perianal, the most symmetrically property distribution.Due to violent gargalesthesia, often making baby's agitation keep crying, sleeping and eating difficulty is pacified, and minority baby also affects body development, if secondary infection, there is also the symptoms such as heating with dyspepsia.Along with the increase of diatery supplement after 6 months, symptom gradually alleviates, most spontaneous recovery in about 1.5 to 2 years old.Part have the baby of allergic constitution can be transformed into chronic, with extremity more than one piece, show as pachylosis, how in lichen sample, desquamation, time and acute attack, sustainable development to childhood period.Owing to pathological changes occurs over just epidermis, if there is no secondary infection or scratching, more after do not stay cicatrix.Only only a few chronic eczema recurrent exerbation or inappropriate medication, will leave over pigmentation or local skin hypertrophy.
Because eczema is a kind of anaphylaxis, so doctor is usually for the curative effect reached, and the external-applied ointment opened containing hormones to baby is treated.And use the hormone of excess can resist the situation of infant physical growth or make some side effect such as thinning of skin or pigmentation.The growth promoter of infant is had adverse effect on.
Summary of the invention
The deficiency existed for prior art, the purpose of invention is to provide a kind of more healthy to user, damp eliminating protective cream that can protect skin and preparation method thereof while treatment eczema.
For achieving the above object, the technical scheme is that a kind of damp eliminating protective cream, it is mixed by following raw material, calculates by mass percentage, is respectively as follows:
Composition
Percentage ratio
Water:
50-70
Butanediol:
2-10
Glycerol:
2-10
Hydrogenate poly-certain herbaceous plants with big flowers alkene:
2-10
White Limnanthes Alba Seed Oil:
2-6
The smooth isostearate of Pyrusussuriensis:
1-4
Polydimethylsiloxane:
1-4
Semen Tritici aestivi germ oil:
1-4
Distearyl dimethylammonium Strese Hofmann's hectorite.:
1-3
Tocopherol acetas:
0.4-0.8
Hydrolecithin:
0.1-0.5
Beta glucan:
0.1-0.3
Bisabolol:
0.1-0.3
N-palmityl hydroxyproline cetyl:
0.05-0.15
Hexyldecanol:
0.05-0.15
Campesterol class:
0.005-0.015
Flos Inulae extract:
0.1-0.3
Hydrolysed rice albumen:
0.2-0.6
Glycyrrhizic acid dipotassium:
0.01-0.09
Dehydroactic acid:
0.01-0.1
Benzyl alcohol:
0.2-1.2
EDETATE SODIUM:
0.01-0.03
The present invention is further arranged to: damp eliminating protective cream further comprises Galla Chinensis extract, and its mass percent is 0.4-1.
The present invention is further arranged to: damp eliminating protective cream further comprises Herba portulacae extract, and its mass percent is 0.1-0.3.
The present invention is further arranged to: damp eliminating protective cream further comprises ginger-root extract, and its mass percent is 0.1-0.6.
By using technique scheme, concrete function and the effect of each chemical composition added in damp eliminating protective cream are described below:
Butanediol: also known as 1,2-butanediol, there is adsorbed water molecule, the effect that moisture-keeping function is superpower, smeared to simultaneously with, clearly, have no sticky sense, moisturizing safety is fabulous, is usually used in skin care item.When human body being carried out interruption and smearing, every other day to smear once, totally 16 days, in all 200 people participating in test, all find no any irritating inflammation；Carrying out eye mask experiment with white mouse 2., the result obtained is still that safety is the highest；Added and carried out the oral cavity test of surrounding in toothpaste as a result, its composition that to oral mucosa also nonirritant, to be a kind of safety the highest.
Glycerol: also known as Glycerin, is without the sweet clear and bright thick liquid of color and taste, odorless, has warm sweet taste.Moisture can be absorbed from air, medical science, weave, in the industry such as printing and dyeing in order to produce hygroscopic agent, it is possible to moisture content is retained, in conjunction with 1, the moisture-keeping functions of 2-butanediol, serve the effect of a dual moisturizing lock water.Make damp eliminating protective cream the most comfortable smearing when, the gentleest to skin.
Hydrogenate poly-certain herbaceous plants with big flowers alkene: hydrogenated polydecene series is the alpha-olefinic of polymerization, uses more at cosmetic industry etc., and clear appearance is transparent and tasteless.There is good economic rationality, chemical inertness, and when it smears to skin, feel the most abundant, smooth and without stagnant sense, have the good compatibility with other oils and fats, and have been found to it and there is good crease-resistant effect, skin is not stimulated, not sensitization, there is good skin condition function.
White Limnanthes Alba Seed Oil: Limnanthes Alba Seed Oil namely Meadowfoam Seed Oil, translator of Chinese is Ramulus et Folium Spiraeae Salicifolia seed oil, Limnanthes Alba Seed Oil, and also someone is white awns flower seed oil, McDonnell Douglas sweet smell flower seed oil, edelweiss extraction oil.At room temperature being in a liquid state, tasteless and non-greasy, skinfeel is the dryest and the comfortableest, has long-acting softness, moisturizing and moist effect.Its chemical constitution includes more than 95% unsaturated long-chain fatty acid, and carbon chain atom number is more than 20, determines its outstanding lubrication and conditioning performance and outstanding oxidation resistance, it is possible to play good skin moistening effect.
The smooth isostearate of Pyrusussuriensis: for faint yellow to yellowish-brown waxy solid, have slight abnormal smells from the patient.Usually use as emulsifying agent in the industries such as cosmetics, medicine, food.When it is dispersed in the surface of dispersate, forms thin film or electric double layer, dispersion phase can be made with electric charge, the droplet of dispersion phase thus can be stoped to condense mutually so that the emulsion of formation is more stable.
Polydimethylsiloxane: its thermostability, tolerance to cold, viscosity vary with temperature little, water proofing property, surface tension are little, have the No Poison of heat conductivity, and its light transmission is good, light transmittance is 100%, due to the physical characteristic that it is outstanding, can be used in cosmetics of everyday use and uses as additive.It is made to have good lubrication to skin, it is possible to play the effect that skin is nursed one's health.
Semen Tritici aestivi germ oil: Semen Tritici aestivi germ oil is a kind of grain germ oil with Fructus Tritici aestivi as waste, it has concentrated the nutrition elite of Semen Tritici aestivi, rich in vitamin E, linoleic acid, linolenic acid, sweet eight carbon alcohol and multiple physiologically active component, be valuable functional food, have the highest nutritive value.Particularly content of vitamin E is the hat of vegetable oil, has been acknowledged as a kind of functional grease having much nutrition health-care functions.There is endocrine regulation, lose weight, prevent mottle, black speck and pigmentation；Antioxidation, reduces lipid peroxide and generates, promote moisture-retention function of skin, makes skin moisten, slow down aging；Enhance metabolism and skin renewal, skin aging crease-resistant, wrinkle resistant, anti-, elimination cicatrix；Regulating blood lipoid, vessel softening, prevention of arterial hardening, hypertension, middle wind action.Semen Tritici aestivi germ oil is applicable to parts of body, after clean skin, takes and is applied in skin surface in right amount, massage gently.Its anti-oxidation function, can effectively protect skin from the injury of natural environment, be particularly effective moistening dry and that circumference of eyes is aging skin, it is possible to play good skin moistening effect.
Distearyl dimethylammonium Strese Hofmann's hectorite.: be a kind of high molecular surfactant, be often solid-state, water insoluble, stable chemical performance, for as emulsion stabilizer.The ability there is excellent thickening, disperseing, adsorbing, degradable.Being frequently used in the field of personal-care supplies so that the performance of product is the most outstanding, viscosity is the best.
Tocopherol acetas: also known as dl-alpha-tocopherol acetate, is one of the form of vitamin E.Faint yellow viscous fluid, relative density 0.957, freezing point-27.5 DEG C, boiling point 200-250 DEG C, refractive index 1.495-1.4972.It is soluble in chloroform, ether, acetone and vegetable oil, is dissolved in alcohol, water insoluble.Thermostability is preferable, and meeting light can be oxidized, and color and luster deepens.Tocopherol acetas prevents the readily oxidizable substance such as cell membrane and intracellular unsaturated fatty acid oxidized in body metabolic processes, thus protects the complete of cell membrane and then prevent the effect of aging, has stronger reproducibility, can be as antioxidant.As internal antioxidant, eliminate interior free yl, reduce the ultraviolet injury to human body.Owing to skin protection, hair care etc. have stronger reproducibility as medicine, nutriment, cosmetics additive vitamin E, during human metabolism, there is antioxidation and then prevent the effect of aging, the normal function of genitals can be kept.
Galla Chinensis extract: Galla Chinensis is a kind of medical herbs, sour in the mouth is puckery, cold in nature.Return lung, large intestine, kidney channel.Have: 1, astriction: owing to tannic acid contained therein has precipitation to protein, after skin, mucosa, ulcer contact tannic acid, its tissue protein is i.e. solidified, cause one layer of tunicle and in astriction, the most oppressed contraction of thin vessels simultaneously, blood clotting and play hemostasia effect；The protein of glandular cell is solidified and causes secretion suppression, produces mucosa and is dried, and the precipitation of teleneuron protein can be in faint local anesthesia phenomenon.Tannic acid can form insoluble compound with some metals, alkaloid or glycoside, functions thus as antidote.Tannic acid without very affecting, alleviates enteritis due to its astriction on normal intestinal motility, therefore can prevent diarrhoea.As in gastrointestinal tract with the presence of the stimulating factor such as antibacterial, poisonous substance, should not use tannic acid preparation.How many tannic acids may interfere with the absorption (precipitating proteins) of food, but in the alkaline environment of small intestinal, protein can be released again, is therefore harmless containing a small amount of tannic acid in food or beverage, but as excessively drunk tea time a large amount of, can delay the absorption of food.Greater amount even can cause stimulation, corrosion, may result in pain on an empty stomach, is vomitting, drops or constipation especially.2. antibacterial action: in vitro tests all has the most antibacterial or bactericidal action to staphylococcus aureus, streptococcus, streptococcus pneumoniae and typhoid fever, paratyphoid fever, dysentery, anthrax, diphtheria, bacillus pyocyaneus etc..Still containing other antibiotic effective ingredients outside Galla Chinensis tannin-removing acid, be mainly distributed on skin zone, the decoct of the Galla Chinensis heart is without antibacterial action.Galla Chinensis decoct has inhibitory action to the influenza PR8 strain of influenza virus type A virus being inoculated in Embryo Gallus domesticus, may be relevant with tannic acid contained therein.100% decoct flat board burrows method, bacillus pyocyaneus, dysentery bacterium, Bacillus proteus, escherichia coli, Bacillus typhi, bacillus enteritidis, anthrax bacillus, diphtheria corynebacterium, staphylococcus aureus, group B streptococcus and streptococcus pneumoniae all there is inhibitory action, its bacteriostasis is not due to the acidity of tannic acid, but because it has consolidation to albumen；Galla Chinensis liquid after ether proposes tannin still has antibacterial action.3. removing toxic substances: tannic acid can form insoluble complex with a lot of heavy metal ion, alkaloid and glycoside, therefore can be used as chemical antidote.In making an addition to damp eliminating protective cream, can be used to the wound festered is had astriction, and simultaneously work as the antibacterial and effect of sterilization, thus reach the more preferable conditioning effect to skin.
Hydrolecithin: lecithin is described as " threeth nutrient " arranged side by side with protein, vitamin, uses the effect serving softening skin in damp eliminating protective cream.Lecithin is the human body indispensable material of each cell, if lacking, will reduce the regeneration capacity of Skin Cell, causing pachylosis, have wrinkle.If suitably absorbing lecithin, skin regeneration vigor just can ensure, adds the good hydrophilic of lecithin and lipophile, and skin is the most glossy.It addition, the inositol contained by lecithin or the main nutrient of hair, alopecia can be suppressed, make poliosis slowly blackening.
Beta glucan: the polysaccharide formed by the bond of glycosidic bond by D-Glucose monomer.It is divided into multiple owing to D-Glucose residue combines the difference of pattern to each other, is distributed widely in microorganism, plant, regnum animale.Its character: colourless or slightly clear yellow viscous solution, slightly characteristic abnormal smells from the patient.Have the following characteristics that 1. excellent immunoactivators.The most powerful free radical scavenger.3. activating macrophage, bite neutrophil cell etc. and remove and caused cell disintegration fragment by radiation.4. macrophage can be made to distinguish and destroy mutant.5. assist damaged tissues such as lymphocyte to add quick-recovery and produce cytokines.6. promoting to include antibiotic, antifungal, anti-parasitic medicine is preferably played effectiveness at interior other drug.7. lower the low density fat in blood, improve high density fat, reduce the generation of hyperlipidemia.Make used for this invention, it is possible to play the nursing role to the wound festered, it is possible to wound is played an antifungal effect, it is possible to more quickly healed in the portion of festering, reached the effect of good skin condition.
Bisabolol: a kind of composition that bisabolol is present in Chamomile, the antiinflammation of Chamomile is essentially from bisabolol.For colourless to Caulis et Folium Oryzae Huang thick liquid, being dissolved in lower alcohol (ethanol, isopropanol), fatty alcohol, glyceride and stone vinegar, almost insoluble in water and glycerol, slight abnormal smells from the patient own, refraction coefficient is 1.492～1.498.Bisabolol is mainly used in skin care and skin care cosmetics, and bisabolol is as active component with protection and nursing allergic skin, and bisabolol is suitable for use in sunscreen product, bath essence after sun tan, baby products and after shaving in nursing product.The stability of bisabolol and well skin-friendliness, it is well suited for being used in cosmetics, and bisabolol preserves for a long time will not variable color, also plastic containers will not be oozed out, using and do not have what problem, bisabolol not only has antiinflammatory performance, has also been proved to bacteriostatic activity.Showing according to data, bisabolol is safe for cosmetics.Can further reach the nursing efficacy to skin.
N-palmityl hydroxyproline cetyl: according to SEPPIC company of France, for the effective anti crease and anti senile prepared old additive of one.Mainly comprise the hydroxyproline derivant of one of composition as collagen protein, N-palmityl hydroxyproline cetyl has preferable skin affinity, and can play the medium transmission effect that hydroxyproline is best in Skin Cell.It was found that N-palmityl hydroxyproline cetyl has the magnetic pole collagen fiber contraction more higher than vitamin C and the effect of suppression elastase activity, and scavenging activated oxygen effectively.This active component as hydroxyproline carrier can with any product having anti aging effect, crease-resistant, cutis laxa or a Function of Antioxygen Free Radical with the use of, in defying age class cosmetics, have the biggest application potential.In the present invention, the interpolation of N-palmityl hydroxyproline cetyl, it is possible to effectively serve crease-resistant, anti-aging effects to skin, has outstanding opsonic action so that skin more water is tender flexible to skin.
Hexyldecanol: Chinese: hexyldecanol;2-hexyl-1-decanol, refractive index: be 1.449.It is applied to the fields such as cosmetics, washing industry dispersant, fiber profit agent, printing profit ink auxiliary agent, advanced lubrication oil additive, bio-pharmaceuticals.1, as the oil component of multiple cosmetics in cosmetics, also it is emulsifying agent, dispersant, solubilizing agent, deodorizer simultaneously；2, textile industry can serve as humidizer, emulsifying agent and antistatic additive；3, as preservative in anti-corrosion of metal industry；4, its ethoxy sulfate and alkyl sulfate are good surfactants.Hexyldecanol is added, it is possible to by its humidification, the effect of lubrication, play the effect of skin moistening in this damp eliminating protective cream.
Campesterol class: be also called Brassica campestris L element sterol, for sterols hormone, is also a class cyclopentanoperhy drophenanthrene, but they is different from the mechanism of action of animal steroid hormone, play a role without nucleus inner recipient, but transmit signal by cell membrane surface receptors.It can promote the growth promoter of cell so that the skin festered can be healed faster, and plays the effect of to skin conditioning.
Flos Inulae extract: Flos Inulae extract contains phylloxanthin and zeaxanthin, ancient Egyptian thinks that its energy slow down aging, Indian's then honor give its flower for holy god, and Flos Inulae contains mineral phosphor and vitamin C.Medical experiment proves that natural carotenol contained in plant is the antioxidant of a kind of excellent performance, adding a certain amount of phylloxanthin in food can prevent cell ageing and biological organs old and feeble, the visual deterioration that senile eyeball retina macular degeneration causes the most also can be prevented with blind, by a series of medical research, carotenoid has been proposed as cancer prevention agent, life extends agent, ulcer inhibitor, heart attack and the inhibitor of coronary artery disease.Introduce Flos Inulae extract in the present invention, make use of its slow down aging and antioxidative effect, smeared to skin surface, it is possible to skin is played further opsonic action.
Herba portulacae extract: use extraction the low temperature method stem from Herba Portulacae and leaf to obtain and there is bioactive extract, and be dissolved in certain density butanediol solution.Herba Portulacae extract antiallergic usefulness is close with " chamomile extract " and " 10% glycyrrhizic acid dipotassium powder ", the flavone simultaneously contained in Herba Portulacae and Saponin have free radical and antioxidation, can be with delay skin aging, there is again the most anti-drying aging, increase skin comfort degree and remove free radical, improving the combination property of skin comfort etc..Being experimentally confirmed, Herba Portulacae extract has obvious antipruritic function and pain and redness is had obvious rejection ability.It is added in this damp eliminating protective cream, the place of eczema can be occurred effectively to alleviate its pruritus degree baby, and can inhibition of pain and redness, skin comfort degree can be increased again simultaneously, can also effective antiallergic to a certain extent, it is possible to play good greater skin conditioning efficacy.
Hydrolysed rice albumen: rice protein is mainly made up of four kinds of albumen such as albumin, globulin, protein,alcohol-soluble and glutelin.Hydrolysed rice albumen, after the protein in rice protein is processed by the hydrolyzable of proteolytic enzyme, the breaks down proteins elite that allotment obtains.Rich in materials such as aminoacid, it is possible to promote that fibrous bud cell produces collagen.It is applied in damp eliminating protective cream of the present invention, can be while playing efficient moisture-retention effect, the defensive enginery of strengthening skin, keep the normal keratinization of horn cell, suppress bacterial reproduction.
Ginger-root extract: being the material that extracts of the root from Rhizoma Zingiberis Recens, its main component includes the peppery alcohol of 6-Rhizoma Zingiberis Recens, 6-shogaol, the peppery alcohol of 8-Rhizoma Zingiberis Recens, the peppery alcohol of 10-Rhizoma Zingiberis Recens.There is enhancing immunity, antibacterial, parasite killing, the effect of antiinflammatory, also there is the strongest oxidation resistance.In traditional medicine circle, it is used for for a long time reducing inflammatory effect.Can play carrying out sterilizing at skin eczema so adding ginger-root extract in damp eliminating protective cream of the present invention, reducing the effect of inflammation.
Glycyrrhizic acid dipotassium: white fine powder, have sweet taste, have the effects such as medicine, can be used for the ointment of collyrium, stomatitis.Corticosteroid compound (suppression metabolic enzyme) can be activated.Indirectly strengthen the effect of corticosteroid compound, can be due to all cosmetics such as cream, frost, water, emulsion, milk and mel, it can neutralize or lower the noxious substance of cosmetics, the anaphylaxis of the cosmetics being also possible to prevent, it is particularly suited for senior hair or in cosmetics, specification on market is UV >=98%, HPLC >=76%.In damp eliminating protective cream of the present invention, add this composition, for regulating the pH value of damp eliminating protective cream, reduce its toxicity so that it is the gentleest to skin.
Dehydroactic acid: another name dehydroacetic acid, solid-state is white or light yellow crystalline powder, odorless, tasteless, fusing point 108～110 DEG C, boiling point 270 DEG C, is a kind of low toxicity efficient corrosion resisting, antifungus agent.Certain antibacterial action is all had under the conditions of acid, alkali, especially the strongest to the inhibitory action of mycete.It is added on damp eliminating protective cream of the present invention interior for suppressing the growth of antibacterial, plays antiseptical effect.
Benzyl alcohol: benzyl alcohol is one of simplest aromatic alcohol, another name: benzylalcohol, crude benzene methanol, benzylalcohol.It is considered as the substituted methanol of phenyl.In nature, majority is presented in ester in essential oil, such as all contain this composition in Flos Jasmini Sambac oil, hyacinth oil and Peruvian balsam.Benzyl alcohol is of many uses in industrial chemical produces.For paint solvent；Photographic developer；PVC stabilizer；Medicine；Synthetic resin solvent；The solvent of vitamin b injection；Ointment or the preservative of medicinal liquid.In damp eliminating protective cream of the present invention, benzyl alcohol and dehydroactic acid are collectively forming a dual anti-corrosion function.
EDETATE SODIUM: be also called disodiumedetate, EDTA-2Na, is a kind of good compounding ingredient in chemistry, and it has six coordination atoms, and the coordination compound of formation is called sequestration thing.There is coordination property widely, almost can form stable chelate with all of metal ion, for white crystalline powder, be dissolved in water.In damp eliminating protective cream of the present invention, add EDETATE SODIUM, make use of its chemical property, play good chelate effect.
Invention further provides the preparation method of a kind of damp eliminating protective cream, as follows:
S1: will include that water, butanediol, glycerol, hydrolecithin, beta glucan, bisabolol, the aqueous phase material of hexyldecanol are stirred and heated to 65 DEG C-75 DEG C, dissolving is uniformly dispersed；
S2: will include that hydrogenated polydecene, white Limnanthes Alba Seed Oil, the smooth isostearate of Pyrusussuriensis, polydimethylsiloxane, Semen Tritici aestivi germ oil, distearyl dimethylammonium Strese Hofmann's hectorite., tocopherol acetas, the oil phase material of N-palmityl hydroxyproline cetyl are stirred and heated to 65 DEG C-77 DEG C, dissolves；
S3: by aqueous phase, oil phase material mix and blend, vacuum emulsifying 12 minutes, be subsequently cooled to 40 DEG C-50 DEG C, evacuation；
S4: after material body is cooled to 40 DEG C-50 DEG C, add the essence preservative including Galla Chinensis extract, campesterol class, Flos Inulae extract, Herba portulacae extract, hydrolysed rice albumen, ginger-root extract, glycyrrhizic acid dipotassium, dehydroactic acid, benzyl alcohol, EDTA disodium, xanthan gum, be sufficiently stirred for homogenizing 4 minutes；
S5: after being cooled to 25 DEG C-35 DEG C, discharging；Sampling censorship, after the inspection of semifinished product is qualified, enters fill operation fill, packaging.
The present invention is by being prepared mentioned component through specific technological process.Can be incorporated in conjunction with the advantage of heterogeneity, it is provided that the damp eliminating protective cream of a kind of notable to infant eczema protection effect and subsidiary conditioning skin function.Have employed the extract component of natural medicinal plants in its composition, non-stimulated to infant, side effect is little, and effects is notable.And while protection eczema, skin can be carried out a comprehensive nursing role.
Detailed description of the invention
Embodiment one:
nullA kind of damp eliminating protective cream，It is as follows that its internal each composition carries out proportioning by its percent mass: the water of 50%，The butanediol of 10%，The glycerol of 10%，The hydrogenation poly-certain herbaceous plants with big flowers alkene of 10%，The white Limnanthes Alba Seed Oil of 5%，The smooth isostearate of Pyrusussuriensis of 4%，The polydimethylsiloxane of 4%，The Semen Tritici aestivi germ oil of 3%，The distearyl dimethylammonium Strese Hofmann's hectorite. of 2%，The tocopherol acetas of 0.4%，The Galla Chinensis extract of 0.4%，The hydrolecithin of 0.1%，The beta glucan of 0.1%，The bisabolol of 0.1%，The N-palmityl hydroxyproline cetyl of 0.06%，The hexyldecanol of 0.05%，The campesterol class of 0.01%，The Flos Inulae extract of 0.1%，The Herba portulacae extract of 0.1%，The hydrolysed rice albumen of 0.2%，The ginger-root extract of 0.1%，The glycyrrhizic acid dipotassium of 0.06%，The dehydroactic acid of 0.01%，The benzyl alcohol of 0.2%，The EDETATE SODIUM of 0.01%.
Embodiment two:
nullA kind of damp eliminating protective cream，It is as follows that its internal each composition carries out proportioning by its percent mass: the water of 60%，The butanediol of 5%，The glycerol of 10%，The hydrogenation poly-certain herbaceous plants with big flowers alkene of 5%，The white Limnanthes Alba Seed Oil of 5%，The smooth isostearate of Pyrusussuriensis of 4%，The polydimethylsiloxane of 2.8%，The Semen Tritici aestivi germ oil of 4%，The distearyl dimethylammonium Strese Hofmann's hectorite. of 2%，The tocopherol acetas of 0.3%，The Galla Chinensis extract of 0.5%，The hydrolecithin of 0.1%，The beta glucan of 0.1%，The bisabolol of 0.1%，The N-palmityl hydroxyproline cetyl of 0.05%，The hexyldecanol of 0.05%，The campesterol class of 0.01%，The Flos Inulae extract of 0.2%，The Herba portulacae extract of 0.1%，The hydrolysed rice albumen of 0.2%，The ginger-root extract of 0.1%，The glycyrrhizic acid dipotassium of 0.07%，The dehydroactic acid of 0.01%，The benzyl alcohol of 0.2%，The EDETATE SODIUM of 0.01%.
Embodiment three:
nullA kind of damp eliminating protective cream，It is as follows that its internal each composition carries out proportioning by its percent mass: the water of 70%，The butanediol of 5%，The glycerol of 4%，The hydrogenation poly-certain herbaceous plants with big flowers alkene of 4%，The white Limnanthes Alba Seed Oil of 2%，The smooth isostearate of Pyrusussuriensis of 4%，The polydimethylsiloxane of 3%，The Semen Tritici aestivi germ oil of 4%，The distearyl dimethylammonium Strese Hofmann's hectorite. of 2%，The tocopherol acetas of 0.3%，The Galla Chinensis extract of 0.5%，The hydrolecithin of 0.1%，The beta glucan of 0.1%，The bisabolol of 0.1%，The N-palmityl hydroxyproline cetyl of 0.05%，The hexyldecanol of 0.05%，The campesterol class of 0.01%，The Flos Inulae extract of 0.1%，The Herba portulacae extract of 0.1%，The hydrolysed rice albumen of 0.2%，The ginger-root extract of 0.1%，The glycyrrhizic acid dipotassium of 0.07%，The dehydroactic acid of 0.01%，The benzyl alcohol of 0.2%，The EDETATE SODIUM of 0.01%.
A kind of method preparing this damp eliminating protective cream, including following step:
S1: will include that water, butanediol, glycerol, hydrolecithin, beta glucan, bisabolol, the aqueous phase material of hexyldecanol are stirred and heated to 65 DEG C-75 DEG C (preferably optimum temperature is 70 DEG C), dissolving is uniformly dispersed；
S2: will include that hydrogenated polydecene, white Limnanthes Alba Seed Oil, the smooth isostearate of Pyrusussuriensis, polydimethylsiloxane, Semen Tritici aestivi germ oil, distearyl dimethylammonium Strese Hofmann's hectorite., tocopherol acetas, the oil phase material of N-palmityl hydroxyproline cetyl are stirred and heated to 65 DEG C-77 DEG C (preferably optimum temperature is 72 DEG C), dissolves；
S3: by aqueous phase, oil phase material mix and blend, vacuum emulsifying 12 minutes, is subsequently cooled to 40 DEG C-50 DEG C (preferably optimum temperature is 45 DEG C), evacuation；
S4: after material body is cooled to 40 DEG C-50 DEG C (preferably optimum temperature is 45 DEG C), add the essence preservative including Galla Chinensis extract, campesterol class, Flos Inulae extract, Herba portulacae extract, hydrolysed rice albumen, ginger-root extract, glycyrrhizic acid dipotassium, dehydroactic acid, benzyl alcohol, EDTA disodium, xanthan gum, be sufficiently stirred for homogenizing 4 minutes；
S5: (preferably optimum temperature is 30 DEG C), discharging after being cooled to 25 DEG C-35 DEG C；Sampling censorship, after the inspection of semifinished product is qualified, enters fill operation fill, packaging.
Experiment: use the damp eliminating protective cream prepared by above-described embodiment, selects the baby of 20 1-6 months, and men and women does not limits, being randomly divided into A, B, C, D tetra-groups, A group uses the product of embodiment one, and B group uses the product of embodiment two, C group uses the product of embodiment three, and D group uses protective cream on the market.By the observation experiment of 8 months, record infant per hour and scratch the number of times meansigma methods at eczema, after the flat key time of festering wounds healing and healing, stay scarred shade degree, the results are shown in Table 1:
In sum, the effect of damp eliminating protective cream of the present invention is substantially better than institute's product sold on the market, on its antipruritic effect, on its wound healing time, the effect after it heals all promotes than product on the market.
The above is the preferred embodiment of the present invention, the most without departing from the principles of the invention, it is also possible to make some modification and improvement, and these also should be regarded as the protection domain that this use is novel.
Claims (5)
1. a damp eliminating protective cream, is characterized in that: it is mixed by following raw material, calculates by mass percentage, is respectively as follows:
Composition
Percentage ratio
Water:
50-70
Butanediol:
2-10
Glycerol:
2-10
Hydrogenate poly-certain herbaceous plants with big flowers alkene:
2-10
White Limnanthes Alba Seed Oil:
2-6
The smooth isostearate of Pyrusussuriensis:
1-4
Polydimethylsiloxane:
1-4
Semen Tritici aestivi germ oil:
1-4
Distearyl dimethylammonium Strese Hofmann's hectorite.:
1-3
Tocopherol acetas:
0.4-0.8
Hydrolecithin:
0.1-0.5
Beta glucan:
0.1-0.3
Bisabolol:
0.1-0.3
N-palmityl hydroxyproline cetyl:
0.05-0.15
Hexyldecanol:
0.05-0.15
Campesterol class:
0.005-0.015
Flos Inulae extract:
0.1-0.3
Hydrolysed rice albumen:
0.2-0.6
Glycyrrhizic acid dipotassium:
0.01-0.09
Dehydroactic acid:
0.01-0.1
Benzyl alcohol:
0.2-1.2
EDETATE SODIUM:
0.01-0.03。
Damp eliminating protective cream the most according to claim 1, is characterized in that: further comprises Galla Chinensis extract, and its mass percent is 0.4-1.
Damp eliminating protective cream the most according to claim 2, is characterized in that: further comprises Herba portulacae extract, and its mass percent is 0.1-0.3.
Damp eliminating protective cream the most according to claim 3, is characterized in that: further comprises ginger-root extract, and its mass percent is 0.1-0.6.
5. a preparation method for damp eliminating protective cream, its feature comprises the following steps:
S1: water, butanediol, glycerol, hydrolecithin, beta glucan, bisabolol, hexyldecanol are heated to 65 DEG C-75 DEG C and stir so that it is dissolve the formation aqueous phase material that is uniformly dispersed；
S2: by hydrogenated polydecene, white Limnanthes Alba Seed Oil, the smooth isostearate of Pyrusussuriensis, polydimethylsiloxane, Semen Tritici aestivi germ oil, distearyl dimethylammonium Strese Hofmann's hectorite., tocopherol acetas, N-palmityl hydroxyproline cetyl are stirred and heated to 65 DEG C-77 DEG C makes it dissolve the formation oil phase material that is uniformly dispersed；
S3: by aqueous phase material, oil phase material mix and blend, vacuum emulsifying 12 minutes, be subsequently cooled to 40 DEG C-50 DEG C, evacuation；
S4: the product prepared in S3 is added the essence preservative including Galla Chinensis extract, campesterol class, Flos Inulae extract, Herba portulacae extract, hydrolysed rice albumen, ginger-root extract, glycyrrhizic acid dipotassium, dehydroactic acid, benzyl alcohol, EDTA disodium, xanthan gum, is sufficiently stirred for homogenizing 4 minutes；
S5: after the product prepared in S4 is cooled to 25 DEG C-35 DEG C, discharging；Sampling censorship, after the inspection of semifinished product is qualified, enters fill operation fill, packaging.
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| CN201510004976.0A CN105816848A (en) | 2015-01-07 | 2015-01-07 | Protective cream capable of dispelling dampness and preparation method thereof |
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|---|---|---|---|
| CN201510004976.0A CN105816848A (en) | 2015-01-07 | 2015-01-07 | Protective cream capable of dispelling dampness and preparation method thereof |
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| CN201510004976.0A Pending CN105816848A (en) | 2015-01-07 | 2015-01-07 | Protective cream capable of dispelling dampness and preparation method thereof |
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| CN110448485A (en) * | 2019-08-13 | 2019-11-15 | 广州艾蓓生物科技有限公司 | A kind of Baby Care cream with removing miliaria and relieving itching effect |
| CN110859989A (en) * | 2019-10-25 | 2020-03-06 | 天津冠勤医药科技有限公司 | Liquid band-aid and preparation method thereof |
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| CN115341399A (en) * | 2022-08-10 | 2022-11-15 | 绍兴市上虞丰达染整有限公司 | Printing and dyeing fixation auxiliary agent for low-temperature dyeing |
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|---|---|---|---|---|
| CN106833268A (en) * | 2017-01-19 | 2017-06-13 | 成都优品化工有限公司 | A kind of aqueous sealing primer for fat content ground high and preparation method thereof |
| CN107811950A (en) * | 2017-12-06 | 2018-03-20 | 佛山微赢电子商务有限公司 | A kind of stern protection cream to baby's skin with nursing effect and preparation method thereof |
| CN107811950B (en) * | 2017-12-06 | 2021-03-02 | 达威控股有限公司 | Hip-protecting cream with nursing effect on skin of baby and preparation method thereof |
| CN110448485A (en) * | 2019-08-13 | 2019-11-15 | 广州艾蓓生物科技有限公司 | A kind of Baby Care cream with removing miliaria and relieving itching effect |
| CN110448485B (en) * | 2019-08-13 | 2022-06-10 | 广州艾蓓生物科技有限公司 | Infant nursing cream with miliaria-removing and itching-relieving effects |
| CN110859989A (en) * | 2019-10-25 | 2020-03-06 | 天津冠勤医药科技有限公司 | Liquid band-aid and preparation method thereof |
| CN111228166A (en) * | 2020-01-10 | 2020-06-05 | 广州贝玛生物科技有限公司 | Soothing skin cream for infants and preparation method thereof |
| CN111544564A (en) * | 2020-04-29 | 2020-08-18 | 娇时日化（杭州）股份有限公司 | Ointment for treating infantile diaper dermatitis and preparation method thereof |
| CN111544564B (en) * | 2020-04-29 | 2023-07-28 | 娇时日化（杭州）股份有限公司 | Ointment for treating infant diaper dermatitis and preparation method thereof |
| CN114632136A (en) * | 2020-12-15 | 2022-06-17 | 浙江养生堂天然药物研究所有限公司 | Skin external composition with enhanced anti-eczema effect |
| CN115341399A (en) * | 2022-08-10 | 2022-11-15 | 绍兴市上虞丰达染整有限公司 | Printing and dyeing fixation auxiliary agent for low-temperature dyeing |
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Effective date of registration: 20190110 Address after: 311200 Dormitories of Cotton and Hemp Research Institute, Tangwan Village, Began Street, Xiaoshan District, Hangzhou City, Zhejiang Province Applicant after: Yu Qiongfei Applicant after: Hangzhou Weikela Investment Co., Ltd. Address before: 311122 No. 1028 Qingliu North Road, Hangzhou Jiangdong Industrial Park, Xiaoshan District, Hangzhou City, Zhejiang Province Applicant before: When Johnson chemical (Hangzhou) Limited by Share Ltd |
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