CN108703930A - A kind of moisturiser and preparation method thereof containing Abelmoschus Esculentus Linn extract - Google Patents
A kind of moisturiser and preparation method thereof containing Abelmoschus Esculentus Linn extract Download PDFInfo
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- CN108703930A CN108703930A CN201810977270.6A CN201810977270A CN108703930A CN 108703930 A CN108703930 A CN 108703930A CN 201810977270 A CN201810977270 A CN 201810977270A CN 108703930 A CN108703930 A CN 108703930A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
Abstract
The present invention is a kind of moisturiser containing Abelmoschus Esculentus Linn extract, and the raw material and weight ratio in formula are respectively:Abelmoschus Esculentus Linn extract 5%;Olive oil 1%;Butyrospermum parkii fruit fatty oil 2%;CalmYang3.0%;Rosmarinus officinalis extract 1%;Aloe vera extract 1%;Cetearyl glucoside 3.0%;Phosphoric acid monohexadecyl ester potassium 0.5%;Dormant oil 5%;Cetostearyl alcohol 2.5%;Dimethyl silicone polymer 1.0%;Lanolin 0.5%;Vaseline 2%;Sodium Hyaluronate 0.1%;Glycerine 10%;Allantoin 0.2%;Parahydroxyacet-ophenone 0.2%;Sodium glucoheptonate 0.02%;Carbomer 0.5%;Polyquaternium-' 22 ' 1%;Decoyl hydroximic acid 0.4%;Deionized water 60.08%, the invention has the advantages that with slim and graceful skin sense and moist care, it is instantaneous to keep skin soft and high resilience, and dry skin can be effectively relieved by the way that plant extracts is added in cream, promote skin moisture content, soft skin, and play the role of Rosemary Extract, improve baby child's resisting skin allergy.
Description
Technical field
The present invention relates to a kind of moisturiser more particularly to a kind of containing the moisturiser of Abelmoschus Esculentus Linn extract and its preparation side
Method.
Background technology
Which can be divided within the scope of 0-3 Sui infant and 3-12 Sui children two in young age according to baby, but either age
The baby of section is virgin, because of the tender sensitivity of its skin, product efficacy predominantly moistens, moisturizing, it is mild it is non-stimulated based on, be developed to at
Before application on human skin is identical, baby child's skin no matter functionally or structurally on all have very big difference with adult, still due to baby's skin
Undeveloped mature, than big, moisture is easy to run off cell table body, therefore, when nursing baby, should be selected by being especially formulated
Baby products can protect baby's skin and stimulation composition, long-acting care baby's skin that can just give treasured so comprehensively
Most the tender feeling most intimate selection and care of precious tender skin.
The ratio between neonatal skin area and weight are more much bigger, which means that every kg body weight was absorbed than being grown up
To wash shield product more much more than being grown up, meanwhile, it is also much strong to the reaction of allergin or toxic substance, it is excessive or inappropriate
Preservative can enable baby child's epidermal cell developmental immaturity, loosely organized, so that epidermis is thinning, easily by environmental stimuli, phylactic power defensive power
Decline;And then can constantly defect be bred by the Skin Cell of preservative damage, enable skin quality worse and worse, parent is always willing as child
Son purchase more gets close to nature, and non-stimulated safe product, this has just pushed directly on preservative free plant extracts baby child and has washed shield
The development in product market.Baby child's skin care market is increasing for " natural plants " and the demand of " antiallergy ", and by okra
Extracting solution is applied to that in baby child's skin-protection product these demands can be solved, the clayey with similar plants sodium hyaluronate and performance production
Product are less, and baby child's moisturizer country of addition okra extracting solution is still blank, and similar product is less.
Main component contains plant polyose, water-soluble in the rare emplastic (sugared condensate) that okra extracting solution includes
Property the ingredients such as fiber, pectin, can be formed " vegetation water glued membrane ", be referred to as " vegetalitas sodium hyaluronate ", moisture, isolation can be kept dirty
Dye;It repairs and is had dry skin caused by calcium deficiency, help promotes skin moisture content, soft skin, can be used as moisturizer;Abundant VC
With anti-oxidation efficacy, phenomena of cutaneous irritation is substantially reduced;Viscosity component plays instant Rosemary Extract, and enhancing skin elasticity is made
With because the peculiar effect moisturizing of okra, soft and moist, smooth, consolidation, anti-oxidant and can be from unique slow release method
The skin problem that many aspects alleviate most of children has the larger market space, is for new product with unique effect
This, our ad hoc meters are a kind of based on the unique efficacy performance of okra extracting solution, and the antianaphylactic plant of a variety of moisturizings of compatibility carries
Object is taken, has moisturizing and antianaphylactic preservative free skin cream.
Invention content
To overcome above-mentioned deficiency, the present invention provides a kind of moisturiser and preparation method thereof containing Abelmoschus Esculentus Linn extract.
A kind of moisturiser containing Abelmoschus Esculentus Linn extract, it is characterized in that:Raw material and weight ratio in formula are respectively:Huang Qiu
Certain herbaceous plants with big flowers extract 5%;Olive oil 1%;Butyrospermum parkii fruit fatty oil 2%;CalmYang3.0%;Rosmarinus officinalis extract 1%;Library
Drag-line aloe extract 1%;Cetearyl glucoside 3.0%;Phosphoric acid monohexadecyl ester potassium 0.5%;Dormant oil 5%;Cetearyl alcohol
Alcohol 2.5%;Dimethyl silicone polymer 1.0%;Lanolin 0.5%;Vaseline 2%;Sodium Hyaluronate 0.1%;Glycerine 10%;Allantois
Element 0.2%;Parahydroxyacet-ophenone 0.2%;Sodium glucoheptonate 0.02%;Carbomer 0.5%;Polyquaternium-' 22 ' 1%;Decoyl
Hydroximic acid 0.4%;Deionized water 60.08%.In the CalmYang containing green tea, centella, rosemary, Radix Glycyrrhizae, giant knotweed,
The extract of scutellaria and german chamomile.
A kind of moisturiser preparation method containing Abelmoschus Esculentus Linn extract, its step are as follows:
A phases:Sodium Hyaluronate 0.1%, glycerine 10%, allantoin 0.2%, parahydroxyacet-ophenone 0.2%, sodium glucoheptonate
0.02%, carbomer 0.5%;
B phases:Olive oil 1%, Butyrospermum parkii fruit fatty oil 2%, cetearyl glucoside 3.0%, cetanol phosphoric acid
Ester potassium 0.5%, dormant oil 5%, cetostearyl alcohol 2.5%, dimethyl silicone polymer 1.0%, lanolin 0.5%, vaseline 2%,
C phases:Abelmoschus Esculentus Linn extract 5%, CalmYang3.0%, Rosmarinus officinalis extract 1%, aloe vera extract
1%, Merquat 280 1%, decoyl hydroximic acid 0.4%
(1) required deionized water 60.08% is injected in kettle, turn on agitator, A phase raw materials is added while stirring, and
80 DEG C -85 DEG C are maintained the temperature at, stops stirring and heating after so that A phase raw materials is completely dissolved;
(2) successively accurately weigh B phases raw material successively be added oil cauldron in, heat while stirring by oil phase be heated to 80 DEG C-
85 DEG C, make to stop stirring and heating when raw material is completely dissolved in oil phase;
(3) after the temperature of the oil phase of the water phase of step (1) and step (2) reaches requirement, first kettle raw material is passed through true
Suction enters to emulsify in pot, then oil cauldron raw material is slowly sucked by vacuum in emulsification pot;
(4) homogenizer is opened 2-3 minutes, emulsifying keeps 80 DEG C or more emulsifying temperatures 30 minutes in emulsification pot
After begin to cool;
(5) a C phase materials are added when cooling to 45 DEG C, are uniformly mixed;
(6) stop stirring when material temperature is down to 35 DEG C~40 DEG C, put the vacuum degree of emulsification pot, prepare discharging.
The invention has the advantages that the present invention not only has pure and fresh, smooth and comfortable use feeling, can provide slim and graceful skin sense and
Moist care instantaneously makes skin soft and high resilience, and by the way that plant extracts and related efficacy are added in cream
Property substance compounded, there are in test moisturizing, soft and moist, smooth, consolidation, the unique effects such as anti-oxidant, can be effectively relieved
Dry skin helps to promote skin moisture content, soft skin, and plays the role of Rosemary Extract, especially greatly improves baby child
Resisting skin allergy.Preservative is not added in the product simultaneously, there is good biological degradability, and irritation is low, meets baby children
The requirement theory of youngster and children's skin care item persistently protect the tender skin of children of baby.
Specific implementation mode:
With reference to embodiment to further detailed description of the present invention, embodiments of the present invention are not limited thereto.
Embodiment 1
A kind of moisturiser containing Abelmoschus Esculentus Linn extract, raw material and weight ratio in formula are respectively:Abelmoschus Esculentus Linn extract
5%;Olive oil 1%;Butyrospermum parkii fruit fatty oil 2%;CalmYang3.0%;Rosmarinus officinalis extract 1%;Aloe barbadensis Miller
Extract 1%;Cetearyl glucoside 3.0%;Phosphoric acid monohexadecyl ester potassium 0.5%;Dormant oil 5%;Cetostearyl alcohol 2.5%;
Dimethyl silicone polymer 1.0%;Lanolin 0.5%;Vaseline 2%;Sodium Hyaluronate 0.1%;Glycerine 10%;Allantoin 0.2%;
Parahydroxyacet-ophenone 0.2%;Sodium glucoheptonate 0.02%;Carbomer 0.5%;Polyquaternium-' 22 ' 1%;Decoyl hydroximic acid
0.4%;Deionized water 60.08% contains green tea, centella, rosemary, Radix Glycyrrhizae, giant knotweed, scutellaria and mother in wherein CalmYang
The extract of chrysanthemum.
A kind of moisturiser preparation method containing Abelmoschus Esculentus Linn extract, its step are as follows:
A phases:Sodium Hyaluronate 0.05%, glycerine 12%, allantoin 0.2%, parahydroxyacet-ophenone 0.2%, glucoheptonic acid
Sodium 0.02%, carbomer 0.5%;
B phases:Olive oil 2%, Butyrospermum parkii fruit fatty oil 1%, cetearyl glucoside 3.0%, cetanol phosphoric acid
Ester potassium 0.5%, dormant oil 7%, cetostearyl alcohol 2%, dimethyl silicone polymer 1.0%, lanolin 1%, vaseline 2%,
C phases:Abelmoschus Esculentus Linn extract 5%, CalmYang2.0%, Rosmarinus officinalis extract 1%, aloe vera extract
0.5%, Merquat 280 1%, decoyl hydroximic acid 0.4%
(1) required deionized water 60.08% is injected in kettle, turn on agitator, A phase raw materials is added while stirring, and
80 DEG C -85 DEG C are maintained the temperature at, stops stirring and heating after so that A phase raw materials is completely dissolved;
(2) successively accurately weigh B phases raw material successively be added oil cauldron in, heat while stirring by oil phase be heated to 80 DEG C-
85 DEG C, make to stop stirring and heating when raw material is completely dissolved in oil phase;
(3) after the temperature of the oil phase of the water phase of step (1) and step (2) reaches requirement, first kettle raw material is passed through true
Suction enters to emulsify in pot, then oil cauldron raw material is slowly sucked by vacuum in emulsification pot;
(4) emulsifying opens homogenizer 2-3 minutes, keeps 80 DEG C or more emulsifying temperatures 30 minutes in emulsification pot
After begin to cool;
(5) a kind of additive (C of compound-CalmYang rich in various plants extract is added when cooling to 45 DEG C
Why the additive of this included CalmYang will also add again in phase) and the other materials of C phases;
(6) stop stirring when material temperature is down to 35 DEG C~40 DEG C, put the vacuum degree of emulsification pot, prepare discharging.Preferably
The detailed description of technical solution
The first composition of the present invention at least contains a kind of pure natural plant origin moisturizer, pure natural in the present invention
Plant origin moisturizer be Abelmoschus esculentus berry extract and aloe vera extract.Gumbo also known as okra, coffee are yellow
Certain herbaceous plants with big flowers, scientific name Abelmoschus esculentus berry extract belong to Malvaceae Abelmoschus, the torrid zone to the temperate regions originating from African northeast, after draw
Enter South Asia, since gumbo fruit shape is slender, as if as ladylike finger, so having a good reputation again in European Region, " gentlewoman is fine
Refer to " Lady ' s finger, it is numerous that gumbo is rich in nutritional ingredient:Plant polyose, pectin, dietary fiber etc., and calcareous content is suitable
Height, even higher than dairy products, the okra place more special relative to other vegetables is the mucus contained inside it, this
Rare emplastic (sugared condensate:Main composition has D- galactolipins, L- rhamnoses, L-arabinose, D- galacturonic acids
Deng) in main component contain pectin, stickiness glycoprotein, cellulose A and potassium, okra crosses the polysaccharide component in mucus, can be formed
" vegetation water glued membrane " keeps moisture, isolation pollution;Repair calcium deficiency caused by have dry skin, help promoted skin moisture content,
Soft skin, can be used as moisturizer, and abundant VC has anti-oxidation efficacy;Adhesive component plays the role of instant Rosemary Extract, autumn
The clayey and performance of certain herbaceous plants with big flowers plant polyose similar plants sodium hyaluronate, smooth sense of touch is dry and comfortable not glutinous greasy after doing, and can help improve product
Skin sense adjusts product quality, the moisture in skin is constantly lost in, and leads to dry water shortage situation, the water that gumbo essence is formed
Glued membrane effectively reduces water loss, while it can discharge the moisture and nutriment itself carried, supplements cutin such as the network of rivers
Layer water content and various small molecule nutritional ingredients, greatly promotes the water storage and defence capability of skin, it is calcareous in addition to be skeleton,
Except the key component of dental health, even more a ring of skin keratinocytes atomization can lose when skin lacks calcium ion
Gloss and elasticity, epidermis can also become sensitive fragile, cause the dry symptoms such as itch of allergy, and okra can help skin rich in calcareous
Skin maintains health, prevents dry skin problem, keeps the skin wet, soft and moist skin.Abelmoschus esculentus berry extract belongs to renewable plant
Source, therefore its source green economy environmental protection, and there is good biological degradability, irritation is low, meets infant and children
The requirement theory of skin care item.
Second of composition of the present invention at least contains a kind of pure natural plant origin emollient, is olive oil and ox
Oily fruit tree fruit fatty oil.Olive oil is a kind of lurid grease of mild band gone out by low-temperature extraction in olive fruit, there is allusion quotation
The nut taste of type, contains abundant vitamin A, vitamin B, vitamin B1、B2、B3, vitamin C and vitamin E, also there are many
Mineral element and amino acid;There is amino acid activating cell, the function of strengthen immunity, olive oil to have excellent moisturizing
Foster skin effect, while also there is certain anti-sunlight function, there is stronger skin permeability, the nutrition of skin can be supplemented,
It is commonly used for the base oil of aromatotherapy;Olive oil moistens non-greasy, can nutrient needed for deep layer supplement skin, it is affine close to
Needed for baby's skin, baby's skin can be enabled to moisten gloss;It is neutral or faintly acid that the present invention, which uses mild adacrya formula, pH, can
The pH value of adjusting baby's skin is assisted, and one layer of moist protective film is left in skin surface, moisture is effectively lockked, prevents baby
Chapped skin extra dry red wine persistently protects the tender skin of children of baby.
Butyrospermum parkii fruit fatty oil is also referred to as shea butter, the wooden fruit oil in Africa, is abundant moisturizing agent, is easy to absorb, be rich in
Unsaturated fatty acid can reinforce the moisture-retaining capacity of skin, and the skin impaired to dryness and cutin can be moistened, by Ka Lite trees
(karite) it extracts.Relative to other plant oil, containing highest rate fat accompaniment, necessary nutrient is especially grown
Triterpene alcohol and vitamin E, vitamin A, allantoin etc., it is full of nutrition.It can prevent skin water loss, help the wound that heals
Mouth increases skin defence capability and compliance.It is rare skin care natural component.
In addition, the antiallergic activity object additive that there is function to improve skin in the present invention, which is one kind, being rich in various plants
The compound of extract -- CalmYang.Contain green tea, centella, rosemary, Radix Glycyrrhizae, giant knotweed, scutellaria and mother in CalmYang
Seven kinds of pure natural plant ingredients of chrysanthemum, thus have and contain Flavonoid substances and catechin in rich and varied effect, such as green tea,
It is reported that:Catechin is a kind of effective anti-infective;Baical Skullcap root P.E has heat-clearing and damp-drying drug, purging intense heat and detonicating and other effects and antioxygen
The pharmacological actions such as change, anticancer, antiviral antibacterial, suchlike pure natural plant extract is added in this product to drop significantly
Low infant symptoms such as inflammation, allergy caused by the factors such as weather, environment, pungent, protect that infant's is delicate
Skin.
A kind of moisturiser containing Abelmoschus Esculentus Linn extract of the present invention meets national sector standard through examining, and items refer to
Mark complies fully with sanitary quality standard and the security requirement of national regulation.
The composition of the present invention is low to the stimulation degree of skin, so-called " low to the stimulation degree of skin ", it is meant that this group
It is more serious unlike pure water to the stimulation degree of skin to close object.
The mode of the property and completion of the present invention will be further illustrated in some examples being set forth below, however, the present invention is simultaneously
It should not be construed as limited to details described in these examples.
Following test method is used in following each implementation:
Human skin patch is tested:Select the volunteer that Pass Test in 18~25 years old requires as study subject,
Skin adverse reaction grade scale:It is shown in Table 1.
1 patch test skin adverse reaction grade scale of table
Normal artificial negative (-);(±) light red spot is suspicious;Erythema, infiltration, papule are (+), weakly positive, erythema, water
Swollen, papule, blister are (++);The middle positive, erythema, oedema, bleb are (+++);The extremely strong positive, notable redness, bubble, necrosis are
(++++)。
Subject, number is selected to be no less than 30 by subject enrollment standard.
1, qualified patch material is selected, tested material is put into spot examination device, dosage is about 0.03g (solid) or 0.03mL
(liquid can be added dropwise on the filter paper appended by spot examination device and be placed in spot examination device).Tested material is the guarantor containing Abelmoschus Esculentus Linn extract
When the wet frost product original, control wells are blank control (not setting any substance), and tested material is that the okra that contains after dilution extracts
When the moisturiser of object, the diluent of the moisturiser is used in control wells.It will be pasted added with the spot of the tested material examination non-stimulated adhesive tape of device
Back or the inner forearm of subject are spread on, side is check plot, and side is trial zone, is gently pressed with palm and is allowed to equably stick
In on skin, continuing (to can adjust the time according to actual conditions) for 24 hours.
2, it is spaced 30min after removal tested material spot examination device, dermoreaction is observed after impression disappearance.If result is feminine gender,
It is observed again respectively with 48h for 24 hours after patch test primary.Reaction result is recorded by 1 dermoreaction grade scale of table, if product passes through
It is feminine gender to observe primary rear result again respectively with 48h for 24 hours, then carries out validity of products assessment.
3, product is effectively assessed
Evaluation of result:It is finally being obtained in 30 subjects the result is that the present invention for skin stimulation be 0, i.e., without instead
It answers.
Claims (3)
1. a kind of moisturiser containing Abelmoschus Esculentus Linn extract, it is characterized in that:Raw material and weight ratio in formula are respectively:Okra
Extract 5%;Olive oil 1%;Butyrospermum parkii fruit fatty oil 2%;CalmYang3.0%;Rosmarinus officinalis extract 1%;Ku La
Rope aloe extract 1%;Cetearyl glucoside 3.0%;Phosphoric acid monohexadecyl ester potassium 0.5%;Dormant oil 5%;Cetostearyl alcohol
2.5%;Dimethyl silicone polymer 1.0%;Lanolin 0.5%;Vaseline 2%;Sodium Hyaluronate 0.1%;Glycerine 10%;Allantoin
0.2%;Parahydroxyacet-ophenone 0.2%;Sodium glucoheptonate 0.02%;Carbomer 0.5%;Polyquaternium-' 22 ' 1%;Decoyl hydroxyl
Oxime acid 0.4%;Deionized water 60.08%.
2. a kind of moisturiser containing Abelmoschus Esculentus Linn extract according to claim 1, it is characterised in that:Described
Contain green tea, centella, rosemary, Radix Glycyrrhizae, giant knotweed, scutellaria and the extract of german chamomile in CalmYang.
3. a kind of moisturiser preparation method containing Abelmoschus Esculentus Linn extract according to claim 1, its step are as follows:
A phases:Sodium Hyaluronate 0.1%, glycerine 10%, allantoin 0.2%, parahydroxyacet-ophenone 0.2%, sodium glucoheptonate
0.02%, carbomer 0.5%;
B phases:Olive oil 1%, Butyrospermum parkii fruit fatty oil 2%, cetearyl glucoside 3.0%, Phosphoric acid monohexadecyl ester potassium
0.5%, dormant oil 5%, cetostearyl alcohol 2.5%, dimethyl silicone polymer 1.0%, lanolin 0.5%, vaseline 2%,
C phases:Abelmoschus Esculentus Linn extract 5%, Rosmarinus officinalis extract 1%, aloe vera extract 1%, gathers CalmYang3.0%
Quaternary ammonium salt -22 1%, decoyl hydroximic acid 0.4%
(1) required deionized water 60.08% is injected in kettle, turn on agitator, A phase raw materials is added while stirring, and keep
Temperature stops stirring and heating at 80 DEG C -85 DEG C after so that A phase raw materials is completely dissolved;
(2) raw material for successively accurately weighing B phases is successively added in oil cauldron, heats while stirring oil phase being heated to 80 DEG C -85
DEG C, make to stop stirring and heating when raw material is completely dissolved in oil phase;
(3) after the temperature of the oil phase of the water phase of step (1) and step (2) reaches requirement, first kettle raw material is inhaled by vacuum
Enter to emulsify in pot, then oil cauldron raw material is slowly sucked by vacuum in emulsification pot;
(4) homogenizer is opened 2-3 minutes, emulsifying keeps 80 DEG C or more emulsifying temperatures in emulsification pot to be opened after 30 minutes
Begin to cool down;
(5) a C phase materials are added when cooling to 45 DEG C, are uniformly mixed;
(6) stop stirring when material temperature is down to 35 DEG C~40 DEG C, put the vacuum degree of emulsification pot, prepare discharging.
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CN111732672A (en) * | 2020-07-22 | 2020-10-02 | 广东省生物工程研究所(广州甘蔗糖业研究所) | Okra polygalacturonic acid with uric acid reducing effect and preparation method and application thereof |
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CN109745264A (en) * | 2019-03-26 | 2019-05-14 | 丹东欣时代生物医药科技有限公司 | A kind of preparation method of the mild moisturiser of no anti-corrosion addition |
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CN111732672A (en) * | 2020-07-22 | 2020-10-02 | 广东省生物工程研究所(广州甘蔗糖业研究所) | Okra polygalacturonic acid with uric acid reducing effect and preparation method and application thereof |
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