CN108452151A - A kind of vaginal care gel - Google Patents
A kind of vaginal care gel Download PDFInfo
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- CN108452151A CN108452151A CN201810214747.5A CN201810214747A CN108452151A CN 108452151 A CN108452151 A CN 108452151A CN 201810214747 A CN201810214747 A CN 201810214747A CN 108452151 A CN108452151 A CN 108452151A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K36/06—Fungi, e.g. yeasts
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention discloses a kind of vaginal care gels, include each component of following parts by weight：10 50 parts of acetic acid chlorhexidine, 45 300 parts of honeysuckle, 0.15 2 parts of peppermint, 40 100 parts of purslane, 100 300 parts of Chinese gall tree, 30 200 parts of climbing groundsel, 10 25 parts of kuh-seng, 30 200 parts of aloe, 10 100 parts of radix scutellariae, 4 10 parts of 4 10 parts of borneol and tocopherol, 20 40 parts of carbomer, 20 40 parts of triethanolamine；Invention additionally discloses the preparation method and applications of the vaginal care gel.The vaginal care gel has excellent antibacterial bacteriostatic and anti-inflammatory effects, suitable for the infection of various vaginal bacterials, trichomonas infection, leukorrhea, monilial infection and uterine neck, genital tract and mucous membrane trauma surface infestation, the cloudy prevention and nursing blown, the healing of the surface of a wound after cervical erosion physiotherapy can be effectively facilitated, improve vaginal dryness, prevent the cross-infections such as sexual intercourse, also have effects that koro, pudendum cleaning, go the kidney deficiency that eliminates the unusual smell, treats, the vaginal care gel without side-effects safely.
Description
Technical field
The invention belongs to bacteriostatic gel technical fields, and in particular to a kind of vaginal care gel.
Background technology
Gel refers to mixture of the granular size between 1 angstrom to 10 angstroms.Polymer Solution and certain colloidal sols, appropriate
Under the conditions of, whole system can be transformed into a kind of stiff substance of the semi-solid state of elasticity, lose flowability.This phenomenon is known as
Gelatification is formed by product and is called gel or colloidal particle in frozen glue colloidal sols or solution or macromolecule in certain condition
Lower interconnection, forms space net structure, is filled in structural void and (also may be used in xerogel as the liquid of decentralized medium
To be gas, xerogel is also referred to as aeroge), such a special dispersion is referred to as gel.There is no mobility.It is internal normal
Contain big quantity of fluid.Such as blood clotting glue, the water content of agar are all up 99% or more.Elastic gel and brittleness gel can be divided into.
After elastic gel loses decentralized medium, volume is reduced significantly, and when reuptaking decentralized medium, volume expands again, example
Such as gelatin.When brittleness gel loses or reuptakes decentralized medium, shape and volume do not change, such as silica gel etc..By molten
The process that liquid or colloidal sol form gel is known as gelatification.
Native Gel is to be present in plant gel (plant in sea and land), animal gel, high mountain gel (mineral) etc. greatly
It is cement existing for nature in nature, but there is their own characteristic.What is extract from these natural materials is complete
New gel component, a variety of gel components are combined with each other, and skin is allowed to experience a kind of feeling having no precedent.From cellulose, plant species
The completely new gel component being extract in son and mineral natural materials synthesizes skin by cement body therein by Biochemical Engineering
In the intercellular lipid that really needs.Deep-sea gel：Containing abundant vitamin, trace quantity mineral substance element, effective pre- anti-aging.
Plant gel：Promote the regeneration of skin, there is anti-inflammatory, calm function.
High mountain gel：Have the function of sterilization, corrosion-resistant and good adsorption capacity.
Animal gel：Activating cell, the elasticity and moisture-retaining capacity for increasing skin.
For dry skin problem, and the skin that can't get rid of is worried, and cosmetics so far mainly supplement water
Point and oil, do not meet skin and really need, have same moisture-keeping functions with nature gel in the Skin Cell of people,
Here it is the important quality factors of gel.Native Gel realizes moist and water lock with good gas permeability, and skin is allowed to keep
Lasting skin-friendly.
Gel skin care item natural, safety, oil-free, no added and fashionable Japanese beauty circle with it, such as pure and beautiful still elegant " cell
Source " imported with original packaging series of products.In China, gel skin care item are in the stage at the early-stage, more well-known as jeru fleshes are such as solidifying
Glue skin care item.But it is contemplated that in the near future, gel skin care item will be favored by more and more Chinese people seeking beauties.
Gynecological gel is suitable for gynaecological imflammation and vagina infection caused by all kinds of pathogenic microorganisms, including：Mycotic (beads
Bacterium) it is a variety of vaginitis such as vaginitis, trichomonas vaginitis, bacterial vaginitis, gonococcal vaginitis, vagina mixed infection, attached
Part inflammation, pelvic infecton, endometritis, veteran form vaginitis and interior cloudy itch, cervical erosion, peculiar smell of smelling as of rotten fish, leucorrhea increasing and
Private parts redness, the antibacterial of itch, antipruritic, cleaning.
The Chinese invention patent application that publication No. is CN103272153A discloses a kind of bacteriostatic gel and preparation method thereof,
Every liter of bacteriostatic gel is made of following raw material：Benzalkonium chloride 1.7-1.9g, glycerine 30-50ml, menthol 0.1-1.3g, alum 1-
1.8g, lactic acid 0.3-0.4g, carbomer 2.5-5g, Chinese medical extract 3-6g, purifying water surplus, the application contain there are many it is anti-inflammatory,
Antibacterial, analgesic composition, by the synergistic effect between each raw material, fungistatic effect is best, and biocompatibility meets GB/
T16886.11-2011, microbiological indicator meet GB15979-2002.It is sexy suitable for the infection of various vaginal bacterials, trichomonad
Dye, leukorrhea, monilial infection, the nursing of uterine neck and genital tract or mucous membrane trauma surface infestation, after promoting cervical erosion physiotherapy
The healing of the surface of a wound.It is nursed after applying also for internal piles, external piles, mixed hemorrhoid, anal fissure, anal-surgery.But the formula of this application is more multiple
Miscellaneous, the bacteriostatic gel side effect of preparation is larger, does not have the additional effects such as koro and pudendum cleaning.
Invention content
The present invention provides a kind of vaginal care gel in view of the drawbacks of the prior art, and the vaginal care gel has the moon
Road cleaning, vagina is antibacterial, vagina anti-inflammatory, koro, vaginal mucosa injury repair, goes to eliminate the unusual smell and restore vagina acid-base balance etc.
Effect.
The purpose of the present invention is what is be achieved through the following technical solutions：
A kind of vaginal care gel, includes each component of following parts by weight：10-50 parts of acetic acid chlorhexidine, honeysuckle 45-
300 parts, 0.15-2 parts of peppermint, 40-100 parts of purslane, 100-300 parts of Chinese gall tree, 30-200 parts of climbing groundsel, kuh-seng 10-25
Part, 30-200 parts of aloe, 10-100 parts of radix scutellariae, 4-10 parts of borneol, 4-10 parts of tocopherol, 20-40 parts of carbomer, triethanolamine
20-40 parts.
Further, include each component of following parts by weight：20-40 parts of acetic acid chlorhexidine, 100-200 parts of honeysuckle,
0.5-1.5 parts of peppermint, 40-80 parts of purslane, 150-200 parts of Chinese gall tree, 80-150 parts of climbing groundsel, 15-20 parts of kuh-seng, aloe
80-160 parts, 40-100 parts of radix scutellariae, 4-8 parts of borneol, 4-8 parts of tocopherol, 20-30 parts of carbomer, 20-30 parts of triethanolamine.
Further, include each component of following parts by weight：30 parts of acetic acid chlorhexidine, 150 parts of honeysuckle, 1 part of peppermint,
60 parts of purslane, 175 parts of Chinese gall tree, 115 parts of climbing groundsel, 18 parts of kuh-seng, 120 parts of aloe, 100 parts of radix scutellariae, 8 parts of borneol are raw
Educate 8 parts of phenol, 25 parts of carbomer, 20 parts of triethanolamine.
A kind of preparation method of the vaginal care gel, includes the following steps：
S1：Kuh-seng is weighed by weight and the ethyl alcohol that the percent by volume of 6 times of weight is 85%, heating and refluxing extraction is added
Twice, about 2h every time, filters to obtain filtrate；
S2：Filter residue in step S1 is added to honeysuckle, purslane, Chinese gall tree, climbing groundsel, the reed weighed by weight
Luxuriant growth, radix scutellariae, borneol and tocopherol mixture in, and impregnate said mixture 3 hours using the purified water of 8 times of weight, decoct
Decocting liquid is extracted after 2h and filter residue is obtained by filtration, and purified water of the above-mentioned filter residue through 6 times of weight is impregnated 3 hours, is extracted after decocting 2h
Decocting liquid merges the decocting liquid obtained twice, filtrate is obtained by filtration；
S3：Filtrate in step S2 is concentrated into the 1/5 of original volume, merges with the filtrate in step S1, stir and continue
Absolute ethyl alcohol is added, adjustment ethyl alcohol concentration of volume percent reaches 60%, stands overnight, collect supernatant, concentrate and recycle second
Alcohol, until extract 1.4-1.6g/ml containing drug concentration, filtration, obtain concentrate；
S4：According to 1：The weight percent of (50-70) weighs carbomer and purified water, and the carbomer is added under room temperature
In purified water, impregnates and stir to carbomer and be completely dissolved, it is spare；
S5：Acetic acid chlorhexidine is weighed by weight and is added into the concentrate of step S3 and is stirred evenly, stirring is equal
Solution after even is added in the solution obtained by step S4, and triethanolamine is added dropwise after stirring evenly by weight, is stirred when being added dropwise
It mixes to homogeneous gel shape object to get the vaginal care gel；
S6：Vaginal care gel loading propeller is dispensed, ethylene oxide sterilizing.
5. a kind of vaginal care gel is in vaginal cleaning, vagina is antibacterial, vagina anti-inflammatory, koro, vaginal mucosa damage
The application in prevention and nursing and anti-inflammatory analgesic field after reparation, internal piles, external piles, mixed hemorrhoid, anal fissure, anal-surgery.
Further, the vaginal care gel is pushed into intravaginal 15-20ml from propeller or is uniformly applied to vulva
Place.
Compared with prior art, the present invention has at least the following advantages：
1. vaginal care gel of the present invention has excellent antibacterial bacteriostatic and anti-inflammatory effects, it is suitable for various the moon
Road bacterial infection, trichomonas infection, leukorrhea, monilial infection and uterine neck, genital tract and mucous membrane trauma surface infestation, the moon blow anti-
It controls and nurses, the healing of the surface of a wound after cervical erosion physiotherapy can be effectively facilitated, improve vaginal dryness, prevent the intersections senses such as sexual intercourse
Dye.
2. vaginal care gel of the present invention has the function of significantly stimulating vagina smooth muscle and sphincter, coagulate
Glue does not enter blood, belongs to physics koro, compacts and shrinks privates.
3. vaginal care gel of the present invention remains menses leukorrhea etc. because privates can be discharged in itself agglomeration,
Good to the cleaning effect of private parts, natural plant formula, product does not enter blood, and without any toxicity and side effects, no chemicals are residual for food-grade
Stay, PH is 4 or so, and product itself is meta-acid, into vagina after can weak acid be diluted to by secretion, the weak acid of vagina can be restored
Property environment, repair privates mucosa injury, go to eliminate the unusual smell.
Specific implementation mode
With reference to embodiment, the invention will be further described, and following embodiment is descriptive, is not limited
, protection scope of the present invention cannot be limited with this.
Acetic acid chlorhexidine：Chlorhexidine acetate also makes Robenidine Roripa, chlorhexidine acetate, Chlorhexidine, double benzyl chlorides double
Guanidine hexane, is cationic surfactant, and has a broad antifungal spectrum has killing effect, to green to most Grain-positives and negative bacteria
Purulence bacillus is also effective.For remote holder of performing the operation, skin, planing surface and sterilization of instruments.
Honeysuckle：Honeysuckle is known as clearing heat and detoxicating good medicine from ancient times.The sweet cold air fragrance of its property, clear heat with drugs of sweet flavour and cold nature is without hindering
Stomach, fragrance reaches thoroughly again can eliminating evil.Honeysuckle can dispelling wind-heat, also kind removing summer-heat blood poison is used for various febrile diseases, such as body heat, hair
The diseases such as rash, macular eruption, heat toxin sore carbuncle, abscess of throat, equal significant effect, can with other medicines compatibility for treat respiratory tract infection,
Bacillary dysentery, acute urinary, hypertension etc. more than 40 plants illness.
Peppermint：Peppermint is Chinese conventional Chinese medicine, and young tender stem tip can make vegetable edible, and herb can be used as medicine again, and cure cold fever laryngalgia,
Headache, conjunctival congestion with ophthalmalgia, myalgia, itchy skin with rubella, the diseases such as measles without adequate eruption are also effective to carbuncle, subcutaneous ulcer, scabies, tinea, dermatitis rhus in addition.
Peppermint contains menthol, the substance can fresh breath and have a variety of pharmacological properties, abdominal pain, gall-bladder problem such as spasm can be alleviated, also had
There are antisepsis and sterilization, diuresis, resolving sputum, stomach invigorating and aid digestion and other effects.Large amounts of food peppermint can cause to have a sleepless night, but low dose of edible
It conduces to sleep.
Purslane：Annual herb, complete stool are hairless.Stem lies down, and paving of throwing oneself on the ground dissipates, branch light green or with kermesinus.Leaf alternate,
Blade is flat, plump, like dent shape, above dirty-green, below light green or with kermesinus；Petiole tubbiness.Flower is contained without stalk, the period of the day from 11 a.m. to 1 p.m
It opens；Bract is lobate；Sepal green, helmet shape；Petal yellow, obovate；Stamen anther yellow；Ovary is hairless.Capsule ovoid；Kind
Careful small, deflection is spherical, and dark brown is glossy.The month at florescence 5-8, fruiting period 6-9 month aerial parts (purslane)：Acid is trembled with fear.Heat-clearing
Removing toxic substances, cooling blood and hemostasis.For hot dysentery purulence blood, heat gonorrhea, vaginal discharge diseases, Carbuncle swells dislikes sore, erysipelas.Seed：Improving eyesight, sharp intestine and small intestine.
Chinese gall tree：Original name Chinese sumac, alias：Chinese gall tree, five times of bavins, Chinese gall, mountain Chinese parasol tree, the wooden Chinese gall, Wu Tao
Leaf, Wu Yanpao, chokedamp peach, ursolic acid peach, red-leaf peach, salt tree root, native Ailanthus altissima, Chinese lantern plant head, red salt fruit, gall nut bavin, angle times, skin poplar
Tree, salt skin, hydrochloric acid are white, Anacardiaceae, Rhus dungarunga or shrub shape.This kind is Gallnut Aphid host plant, in children
Insect gall, i.e. Chinese gall are formed on branch and leaf, is industrially used for tanning, medicine, plastics and ink etc..Sprout and Ye Ke make native agriculture
Medicine.The soaked generation vinegar of fruit is used, and eats that acid is salty to quench the thirst raw.Seed can extract oil.Root, leaf, flower and fruit are available for medicinal.Melaphis chinensis Baker on leaf
Insect gall (Chinese gall)：It is sour, puckery, it trembles with fear.It astringes the lung fall fire, relieving diarrhea with astringents, arrest sweating, hemostasis, hygroscopic sore.For chronic cough of deficiency lung, long
Dysentery chronic diarrhea, spitting of blood, bleeding from five sense organs or subcutaneous tissue are had blood in stool, hemorrhoid blood, kidney deficiency, seminal emission, the enuresis, spontaneous perspiration, night sweat；It is used for rectal prolapse, the prolapse of uterus, wet sore, goose mouthful outside
Sore, cervical erosion, sore furuncle poison, traumatic hemorrhage.Fruit (salt skin)：It is sour, salty, it is cool.Body-fluid-generating heat-clearing, moistening lung for removing phlegm, arrest sweating.With
In larynx numbness, phlegm-fire cough, wine poison jaundice, malignant malaria, fulminant dysentery, body void hidrosis, seborrheic dermatitis of the scalp, stubborn dermatitis, carbuncle poison festers.Root or root skin
(salt skin root)：It is sour, salty, it is cool.It is clearing heat and detoxicating, wind-damp dispelling, scattered blood stasis.For cold, fever, uterine bleeding, cough spitting of blood, diarrhea, Huang
Subcutaneous ulcer, oedema are had blood in stool, hemorrhoid hemorrhage, arthralgia pain due to rheumatism；It is used for traumatic injury outside, traumatic bleeding, snake bite, acute mastitis are tinea, sore, wet
Rash.Leaf (leaf of the Chinese sumac)：Acid, at cool.Preventing phlegm from forming and stopping coughing, removing toxic substances.It coughs, has blood in stool for phlegm, dysentery；It is used for traumatic injury, snake, dog outside
It bites, traumatic bleeding, wasp sting, psoriasis, eczema, dermatitis rhus root bast (salt skin root from skin)：It is salty, puckery, it is cool.Wind-damp dispelling,
Scattered blood stasis, it is clearing heat and detoxicating.For coughing, treating rheumatic ostealgia, oedema, jaundice, traumatic injury, pyogenic infections sore scabies, snake bite.Bark it is tough
Skin zone：For bloody flux, pyogenic infections, sore scabies.Flower：For nasal eczema, carbuncle turgescence canker.
Climbing groundsel：(Senecio scandens Buch.-Ham.ex D.Don) also known as nine inner bright, Herba Senecionis Scandentis, a thousand li
And bright stroke of eye, sweet vernal grass Broomjutre Sida Herb, Kowloon light, nine ridge light.For catananche, be born under hillside, sparse woods, Lin Bian, road
In other, limes marginis thick grass.Originate in Henan, Shaanxi, Jiangsu, Zhejiang, Guangxi, Sichuan.Its is cold in nature, bitter, have it is clearing heat and detoxicating, it is bright
Mesh, it is antipruritic and other effects.It is chiefly used in anemopyretic cold, red eye, swell pain, dysentery, skin eczema boil.It is worth noting that, with existing
Similar in the chrysanthemum Radix Notoginseng of report, Senecio the plant mostly Pyrrolizidine of poison containing liver alkaloid, acute and chronic poisoning can cause liver
Sinus hepaticus obstruction syndrome, liver macrocytosis or liver fibrosis.50% decoction, to shiga's dysentery bar mattress and golden yellow grape
It is respectively 1 that coccus, which has stronger antibacterial action, effective concentration,:1024 and 1:512, to typhoid fever, paratyphoid A, paratyphoid B, dysentery
The bacillus such as (Freund, Boydii, sonnei), large intestine, deformation, cured sample anthrax and sarcine all have inhibiting effect (two in test tube
Times dilution method).Oral absorption is good (rat), and the urine of discharge also has certain antibacterial action, is widely used in the trichomonas the moon for the treatment of
Road is scorching.
Kuh-seng：Chinese medicine name.For the dry root of legume kuh-seng, spring, the excavation of two season of autumn remove root head and small supporting root, wash
Only, dry, or fresh slices are taken advantage of, it is dry.It is bitter, trembles with fear.There are heat-clearing and damp-drying drug, desinsection, the work(of diuresis.For hot dysentery, have blood in stool, jaundice urine
It closes, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, mange leprosy controls trichomonas vaginitis outside.
Aloe：Luxuriant growth (scientific name：Aloe vera) it is that Aloe is for many years for A Fu flowers section (also known as Asphodelaceae, Eremurus chinensis section)
Raw evergreen herbage, leafage is raw, big and plump, in seat shape or is born in stem top, the normal lanceolar of leaf or the short width of leaf, there is pointed tooth at edge
Shape pierces.Inflorescence is umbrella shape, total shape, spike, cone etc., and color is in red, yellow or tool redness of the skin or complexion spot, six, petal, six pieces of gynoecium.Flower
By the more joints of base portion at tubular.Bactericidal effect, anti-inflammatory effect moisten beautification function, the effect of letting out under stomach invigorating, and cardiac stimulant promoting blood circulation acts on,
Immune and palingenesis, is immunized and antitumor action, detoxication, anti-aging effects ease pain, sedation, anti-sunlight function.
Radix scutellariae：Radix scutellariae (Classification system：Scutellariabaicalensis Georgi), the golden tea of alias Radix Scutellariae, soil
Root is lamiaceae labiatae scutellaria herbaceos perennial；Meat rhizome is plump, leaf heavily fortified point papery, lanceolar to wire lanceolar, total shape
Inflorescence basidixed on stem and branch, corolla is purple, purplish red to blue, and filigree is flat, and style is elongated, and floral disc is cyclic annular, ovary brown, small heavily fortified point
Fruit ovoid, 7~September of flowering fruit bearing stage.Excess fire is rushed down, except damp and hot, hemostasis, tocolysis.Control high fever polydipsia, cough with lung heat, damp-heat dysentery, Huang
Subcutaneous ulcer, heat gonorrhea are spat, are defeated in battle, collapse, are leaked, red eye, swell pain, fetal irritability, carbuncle swells furunculosis.
Borneol：Borneol (Classification system：) also known as piece brain, orange slices, L-Borneol, kapur, MEIHUA BINGPIAN, castrated ram cloth sieve Borneol
Perfume, plum blossom brain, borneol brain, Mei Bing etc., be by composite family Blumea balsamifera cauline leaf or canella borneol camphor tree branches and leaves through steam distillation simultaneously
It recrystallizes and obtains.Also useful turpentine oil is obtained through a series of chemical method techniques.It can be used for closing card coma, swells for hot eyes
Bitterly, larynx numbness aphtha, be used for sore swell and ache curative, burst after do not hold back.
Tocopherol：Tocopherol, that is, vitamin E (Ve), natural tocopherol are all d- tocopherols (dextroform), it have α, β,
7 kinds of isomers such as γ, δ, wherein the activity with mono- tocopherols of α is most strong.The tocopherol mixing used as antioxidant is dense
Contracting object (d-mixed-tocopherol concentrate) is the mixture of the various isomers of natural tocopherol.It is raw
Educate the natural oil-soluble inhibitor that phenol is current mass production.In whole-fat milk powder, cream or margarine, meat products, aquatic products
It is had a wide range of applications in processed goods, dehydrated vegetables, fruit drink, frozen food and instant food etc., especially tocopherol is made
Important meaning is had more for the antioxidant and nutrition fortifier of baby food, remedy diet, condensed food etc., has and increases
The antioxidation of cell maintains and promotes Reproductive Performance, is usually used in preventing habitual abortion and threatened abortion and climacteric
The treatment of phase syndrome.For hepatitis, the auxiliary treatment of hepatic sclerosis, muscular dystrophy.
Carbomer：This product is the high molecular polymer that acrylic acid is bonded allyl sucrose or pentaerythrite allyl ether.By dry
Dry product calculate, and (- COOH) containing carboxylic acid group should be 56.0%~68.0%.Card wave is also referred to as carbomer (carbomer), is with season penta
The acrylic acid crosslinked resin that tetrol etc. is crosslinked with acrylic acid is a kind of very important rheology control agent, the card after neutralization
Wave is outstanding gel-type vehicle, has the important uses such as thickening, suspension, simple for process, stability is good, is widely used in lotion, cream
In frost, gel.Card wave be Nuo Yu companies of the U.S. specialty (predecessor be Gu Lide companies of the U.S., most ancient company of the U.S. it
One), product includes Carbopol series rheology modifier and Pemulen series polymer emulsifiers.
Triethanolamine：I.e. three (2- ethoxys) amine, can regard the trihydroxy substituent of triethylamine as.With other amines
It is similar to close object, since there are lone pair electrons, triethanolamine to have alkalescent on nitrogen-atoms, can be given birth to inorganic acid or organic acid reaction
At salt.It is used as emulsifier, moisturizer, humidizer, thickening in cosmetics (including skin washing, eye glue, moisturizing, shampoo etc.)
Agent, PH poising agents.For being neutralized into soap with aliphatic acid in cosmetic formulations, amine salt is neutralized into sulfated fatty acid.Three second
Hydramine is that emulsifier is commonly used in cream preparation, has lotion exquisiteness, the spy of lotion brilliant white with the cream products that triethanolamine emulsifies
Point, another triethanolamine and the colloid phase stability that higher fatty acids or higher aliphatic are formed are good, and product quality is stablized, and can hold outer
Addition divides proportion height.Triethanolamine is the most frequently used neutralizer containing the acid high-molecular gel such as carbomer, and triethanolamine passes through
It is neutralized with carboxyls such as carbomers, forms stable macromolecular structure, reach the application effect of thickening and moisturizing.Pharmaceutic adjuvant.It can
Solvent as casein, shellac, dyestuff etc..Fibre finish, anticorrosive additive, plasticizer, soup is also acted as to add
Add agent, carbon on engine preventing agent etc..As plasticizer, neutralizer, lubricant additive or anticorrosive and dyestuff, tree
The dispersant of fat etc..Also act as synthetic surfactant, stabilizer.
Cordyceps sinensis, Chinese medicine name.For Clavicipitaceae plant aweto Cordyceps sinensis (BerK.)
Sacc. the complex of the corpse of the stroma and larva on Hepialidae insect larvae is colonized in.With kidney tonifying benefit lung, hemostasis and phlegm
Effect.Cure mainly impotence and seminal emission, soreness of waist and knee joint, chronic cough and dyspnea of deficiency type, overstrain cough phlegm blood.
Pilose antler refers to the unossified and young horn with fine hair of the stag of sika deer or red deer.It is rare medicinal herbs.Contain in pilose antler
Ingredients, the wherein aminoacid ingredient such as phosphatide, glycolipid, glue fat, hormone, aliphatic acid, amino acid, protein and calcium, phosphorus, magnesium, sodium account for
More than half of total ingredient.
Semen Cuscutae (scientific name：Cuscuta chinensis Lam.), alias abdicates true, beans parasitism, beans King of Hell, yellow silk, yellow silk
Rattan, Caulis Spatholobi, spun gold rattan etc..Annual parasitism draft.Stem is wound, and yellow is very thin, no leaf.Inflorescence side is given birth to, few to spend or spend more cluster
Generate small umbrella shape or small glomerule；Bract and squamella are small, flakey；Bennet is slightly sturdy；Calyx cup-shaped connects below middle part
It closes, sliver triangular shape；Corolla white, pot shape；Stamen the micro- lower place of raw corolla lobe sinus；Scale oblong；Ovary is subsphaeroidal,
Style 2.Capsule is spherical, is almost all the corolla harbored and is surrounded.Seed 2-49, it is filbert, it is oval, it is about 1 millimeter, surface is thick
It is rough.Seed is medicinal, there is the function of filling liver kidney, benefiting male body essence and invigorating sex functions and antidiarrheal.
Chinese yam：Chinese yam is also known as Chinese yam, native potato, sweet potato Chinese yam, RHIIZOMA DIOSCOREAE from Henan of China, Chinese yam, white Chinese yam, is《Chinese book on Chinese herbal medicine》The grass recorded
Medicine, medicinal source are Dioscoreaceae plant Chinese yam dry rhizome.Chinese yam has nourishing strong, aid digestion, holds back abnormal sweating, the work(of antidiarrheal
Effect cures mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes are quenched one's thirst, oliguria frequency, seminal emission, women is with lower and dyspeptic chronic intestines
It is scorching.Chinese yam optimum is taken with ganoderma lucidum collocation, has the function of preventing diabetes, Chinese yam has greatly hair on grocery trade and processing industry
Open up future.
Deer whip, Chinese medicine name.Also known as deer kidney, deer punching.For animal in deer family sika deer or the external genital organs of red deer male.Kill deer
Afterwards, penis and testis, cleared residual meat and grease are extracted, be fixed on plank air-dry.With it is coarse, glossy, without residual meat and oil
Fat, free from insect pests, drying person are preferred.《Traditional Chinese Medicine in Sichuan will》：Warm-natured, taste is salty pungent, nontoxic；Enter liver, kidney, bladder three to pass through；Control impotence, kidney
Empty syrigmus, married woman's cold uterus, fails to be impregnated for a long time, chronic testis inflammation.But the careful clothes of innate excess of YANG in the body person.Deer whip is easy to use, can steep
Wine makes herbal cuisine, if old whip can directly be eaten it raw.Mei flower spirit, main product is in Jilin, Liaoning, Hebei and other places；Red deer whip, it is main
Originate in the ground such as Heilungkiang, Jilin, the Inner Mongol.
HERBA EPIMEDII：HERBA EPIMEDII be called just before, Herba Epimedii, celestial spirit adjoin, Herba Epimedii, thousand liang of gold, dry chicken muscle, coptis ancestral, three
Nine leaves etc., HERBA EPIMEDII have the effect of tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, strengthening the muscles and bones, HERBA EPIMEDII to have treatment impotence and seminal emission, void cold not
It educates, the effect that frequent micturition incontinence, dyspnea and cough due to deficiency of the kidney, soreness and weakness of waist and knees, arthralgia pain due to rheumatism, hemiplegia, four limbs are meciless, the deficiency of Yin and mutually fiery movability
Person's wood taboo takes HERBA EPIMEDII.
Embodiment 1
A kind of vaginal care gel, includes each component of following parts by weight：10 parts of acetic acid chlorhexidine, 45 parts of honeysuckle,
2 parts of peppermint, 100 parts of purslane, 100 parts of Chinese gall tree, 200 parts of climbing groundsel, 10 parts of kuh-seng, 30 parts of aloe, 100 parts of radix scutellariae, ice
4 parts of piece, 10 parts of tocopherol, 40 parts of carbomer, 20 parts of triethanolamine.
The preparation method of above-mentioned vaginal care gel, includes the following steps：
S1：Kuh-seng is weighed by weight and is added in the absolute ethyl alcohol that the percent by volume of 6 times of weight is 85%, is heated back
Twice, about 2h, filters to obtain filtrate every time for stream extraction；
S2：Filter residue in step S1 is added to honeysuckle, purslane, Chinese gall tree, climbing groundsel, the reed weighed by weight
Luxuriant growth, radix scutellariae, borneol and tocopherol mixture in, and impregnate said mixture 3 hours using the purified water of 8 times of weight, decoct
Decocting liquid is extracted after 2h and filter residue is obtained by filtration, and purified water of the above-mentioned filter residue through 6 times of weight is impregnated 3 hours, is extracted after decocting 2h
Decocting liquid merges the decocting liquid obtained twice, filtrate is obtained by filtration；
S3：Filtrate in step S2 is concentrated into the 1/5 of original volume, merges with the filtrate in step S1, stir and continue
Absolute ethyl alcohol is added, adjustment ethyl alcohol concentration of volume percent reaches 60%, stands overnight, collect supernatant, concentrate and recycle second
Alcohol, until extract 1.4g/ml containing drug concentration (the wherein described drug concentration refers to supernatant after concentrating and recycling ethyl alcohol,
The concentration of contained Chinese medicinal ingredients, similarly hereinafter), filtration obtains concentrate；
S4：According to parts by weight 1：50 weigh carbomer and purified water, the carbomer are added in purified water under room temperature, leaching
It steeps and stirs to carbomer and be completely dissolved, it is spare；
S5：Acetic acid chlorhexidine is weighed by weight and is added into the concentrate of step S3 and is stirred evenly, stirring is equal
Solution after even is added in the solution obtained by step S4, and triethanolamine solution is added dropwise after stirring evenly by weight, and side is added dropwise
While being stirred until homogeneous gelling material to get the vaginal care gel；
S6：Vaginal care gel loading propeller is dispensed, ethylene oxide sterilizing.
Embodiment 2
A kind of vaginal care gel, includes each component of following parts by weight：50 parts of acetic acid chlorhexidine, 300 parts of honeysuckle,
0.15 part of peppermint, 40 parts of purslane, 300 parts of Chinese gall tree, 30 parts of climbing groundsel, 25 parts of kuh-seng, 200 parts of aloe, 10 parts of radix scutellariae, ice
4 parts of 10 parts of piece and tocopherol, 20 parts of carbomer, 40 parts of triethanolamine.
A kind of preparation method of the vaginal care gel, includes the following steps：
S1：Weigh by weight kuh-seng and be added 6 times of weight 85% absolute ethyl alcohol in, heating and refluxing extraction twice,
Each about 2h, filters to obtain filtrate；
S2：Filter residue in step S1 is added to honeysuckle, purslane, Chinese gall tree, climbing groundsel, the reed weighed by weight
Luxuriant growth, radix scutellariae, borneol and tocopherol mixture in, and impregnate said mixture 3 hours using the purified water of 8 times of weight, decoct
Decocting liquid is extracted after 2h and filter residue is obtained by filtration, and purified water of the above-mentioned filter residue through 6 times of weight is impregnated 3 hours, is extracted after decocting 2h
Decocting liquid merges the decocting liquid obtained twice, filtrate is obtained by filtration；
S3：Filtrate in step S2 is concentrated into the 1/5 of original volume, merges with the filtrate in step S1, stir and continue
Absolute ethyl alcohol is added, adjustment ethyl alcohol concentration of volume percent reaches 60%, stands overnight, collect supernatant, concentrate and recycle second
Alcohol, until extract 1.6g/ml containing drug concentration, filtration, obtain concentrate.
S4：According to parts by weight 1：70 weigh carbomer and purified water, the carbomer are added in purified water under room temperature, leaching
It steeps and stirs to carbomer and be completely dissolved, it is spare.
S5：Acetic acid chlorhexidine is weighed by weight and is added into the concentrate of step S3 and is stirred evenly, stirring is equal
Solution after even is added in the solution obtained by step S4, and triethanolamine solution is added dropwise after stirring evenly by weight, and side is added dropwise
While being stirred until homogeneous gelling material to get the vaginal care gel；
S6：Vaginal care gel loading propeller is dispensed, ethylene oxide sterilizing.
Embodiment 3
A kind of vaginal care gel, includes each component of following parts by weight：40 parts of acetic acid chlorhexidine, 100 parts of honeysuckle,
1.5 parts of peppermint, 40 parts of purslane, 200 parts of Chinese gall tree, 150 parts of climbing groundsel, 15 parts of kuh-seng, 160 parts of aloe, 40 parts of radix scutellariae, ice
8 parts of 8 parts of piece and tocopherol, 30 parts of carbomer, 20 parts of triethanolamine.
A kind of preparation method of the vaginal care gel, includes the following steps：
S1：Weigh by weight kuh-seng and be added 6 times of weight 85% absolute ethyl alcohol in, heating and refluxing extraction twice,
Each about 2h, filters to obtain filtrate；
S2：Filter residue in step S1 is added to honeysuckle, purslane, Chinese gall tree, climbing groundsel, the reed weighed by weight
Luxuriant growth, radix scutellariae, borneol and tocopherol mixture in, and impregnate said mixture 3 hours using the purified water of 8 times of weight, decoct
Decocting liquid is extracted after 2h and filter residue is obtained by filtration, and purified water of the above-mentioned filter residue through 6 times of weight is impregnated 3 hours, is extracted after decocting 2h
Decocting liquid merges the decocting liquid obtained twice, filtrate is obtained by filtration；
S3：Filtrate in step S2 is concentrated into the 1/5 of original volume, merges with the filtrate in step S1, stir and continue
Absolute ethyl alcohol is added, adjustment ethyl alcohol concentration of volume percent reaches 60%, stands overnight, collect supernatant, concentrate and recycle second
Alcohol, until extract 1.5g/ml containing drug concentration, filtration, obtain concentrate.
S4：According to parts by weight 1：60 weigh carbomer and purified water, the carbomer are added in purified water under room temperature, leaching
It steeps and stirs to carbomer and be completely dissolved, it is spare.
S5：Acetic acid chlorhexidine is weighed by weight and is added into the concentrate of step S3 and is stirred evenly, stirring is equal
Solution after even is added in the solution obtained by step S4, and triethanolamine solution is added dropwise after stirring evenly by weight, and side is added dropwise
While being stirred until homogeneous gelling material to get the vaginal care gel；
S6：Vaginal care gel loading propeller is dispensed, ethylene oxide sterilizing.
Embodiment 4
A kind of vaginal care gel, includes each component of following parts by weight：20 parts of acetic acid chlorhexidine, 200 parts of honeysuckle,
0.5 part of peppermint, 80 parts of purslane, 150 parts of Chinese gall tree, 80 parts of climbing groundsel, 20 parts of kuh-seng, 80 parts of aloe, 100 parts of radix scutellariae, ice
4 parts of 4 parts of piece and tocopherol, 20 parts of carbomer, 30 parts of triethanolamine.
A kind of preparation method of the vaginal care gel, includes the following steps：
S1：Weigh by weight kuh-seng and be added 6 times of weight 85% absolute ethyl alcohol in, heating and refluxing extraction twice,
Each about 2h, filters to obtain filtrate；
S2：Filter residue in step S1 is added to honeysuckle, purslane, Chinese gall tree, climbing groundsel, the reed weighed by weight
Luxuriant growth, radix scutellariae, borneol and tocopherol mixture in, and impregnate said mixture 3 hours using the purified water of 8 times of weight, decoct
Decocting liquid is extracted after 2h and filter residue is obtained by filtration, and purified water of the above-mentioned filter residue through 6 times of weight is impregnated 3 hours, is extracted after decocting 2h
Decocting liquid merges the decocting liquid obtained twice, filtrate is obtained by filtration；
S3：Filtrate in step S2 is concentrated into the 1/5 of original volume, merges with the filtrate in step S1, stir and continue
Absolute ethyl alcohol is added, adjustment ethyl alcohol concentration of volume percent reaches 60%, stands overnight, collect supernatant, concentrate and recycle second
Alcohol, until extract 1.5g/ml containing drug concentration, filtration, obtain concentrate.
S4：According to parts by weight 1：60 weigh carbomer and purified water, the carbomer are added in purified water under room temperature, leaching
It steeps and stirs to carbomer and be completely dissolved, it is spare.
S5：Acetic acid chlorhexidine is weighed by weight and is added into the concentrate of step S3 and is stirred evenly, stirring is equal
Solution after even is added in the solution obtained by step S4, and triethanolamine solution is added dropwise after stirring evenly by weight, and side is added dropwise
While being stirred until homogeneous gelling material to get the vaginal care gel；
S6：Vaginal care gel loading propeller is dispensed, ethylene oxide sterilizing.
Embodiment 5
A kind of vaginal care gel, includes each component of following parts by weight：30 parts of acetic acid chlorhexidine, 150 parts of honeysuckle,
1 part of peppermint, 60 parts of purslane, 175 parts of Chinese gall tree, 115 parts of climbing groundsel, 18 parts of kuh-seng, 120 parts of aloe, 100 parts of radix scutellariae, ice
20 parts of 8 parts of piece, 8 parts of tocopherol, 25 parts of carbomer and triethanolamine.
A kind of preparation method of the vaginal care gel, includes the following steps：
S1：Weigh by weight kuh-seng and be added 6 times of weight 85% absolute ethyl alcohol in, heating and refluxing extraction twice,
Each about 2h, filters to obtain filtrate；
S2：Filter residue in step S1 is added to honeysuckle, purslane, Chinese gall tree, climbing groundsel, the reed weighed by weight
Luxuriant growth, radix scutellariae, borneol and tocopherol mixture in, and impregnate said mixture 3 hours using the purified water of 8 times of weight, decoct
Decocting liquid is extracted after 2h and filter residue is obtained by filtration, and purified water of the above-mentioned filter residue through 6 times of weight is impregnated 3 hours, is extracted after decocting 2h
Decocting liquid merges the decocting liquid obtained twice, filtrate is obtained by filtration；
S3：Filtrate in step S2 is concentrated into the 1/5 of original volume, merges with the filtrate in step S1, stir and continue
Absolute ethyl alcohol is added, adjustment ethyl alcohol concentration of volume percent reaches 60%, stands overnight, collect supernatant, concentrate and recycle second
Alcohol, until extract 1.5g/ml containing drug concentration, filtration, obtain concentrate.
S4：According to parts by weight 1：60 weigh carbomer and purified water, the carbomer are added in purified water under room temperature, leaching
It steeps and stirs to carbomer and be completely dissolved, it is spare.
S5：Acetic acid chlorhexidine is weighed by weight and is added into the concentrate of step S3 and is stirred evenly, stirring is equal
Solution after even is added in the solution obtained by step S4, and triethanolamine solution is added dropwise after stirring evenly by weight, and side is added dropwise
While being stirred until homogeneous gelling material to get the vaginal care gel；
S6：Vaginal care gel loading propeller is dispensed, ethylene oxide sterilizing.
Embodiment 6
A kind of vaginal care gel, includes each component of following parts by weight：30 parts of acetic acid chlorhexidine, 150 parts of honeysuckle,
1 part of peppermint, 60 parts of purslane, 175 parts of Chinese gall tree, 115 parts of climbing groundsel, 18 parts of kuh-seng, 120 parts of aloe, 100 parts of radix scutellariae, ice
8 parts of 8 parts of piece and tocopherol, 25 parts of carbomer, 20 parts of triethanolamine, 30 parts of cordyceps sinensis, 12 parts of pilose antler, 15 parts of Semen Cuscutae, mountain
30 parts of medicine, 20 parts of deer whip, 17 parts of HERBA EPIMEDII.
A kind of preparation method of the vaginal care gel, includes the following steps：
S1：Weigh by weight kuh-seng and be added 6 times of weight 85% absolute ethyl alcohol in, heating and refluxing extraction twice,
Each about 2h, filters to obtain filtrate；
S2：Filter residue in step S1 is added to honeysuckle, purslane, Chinese gall tree, climbing groundsel, the reed weighed by weight
Luxuriant growth, radix scutellariae, borneol, tocopherol, cordyceps sinensis, pilose antler, Semen Cuscutae, Chinese yam, deer whip and HERBA EPIMEDII mixture in, and use 8
The purified water of times weight impregnates said mixture 3 hours, decocts extraction decocting liquid after 2h and filter residue is obtained by filtration, above-mentioned filter residue is passed through
The purified water of 6 times of weight is impregnated 3 hours, is extracted decocting liquid after decocting 2h, is merged the decocting liquid obtained twice, filtrate is obtained by filtration；
S3：Filtrate in step S2 is concentrated into the 1/5 of original volume, merges with the filtrate in step S1, stir and continue
Absolute ethyl alcohol is added, adjustment ethyl alcohol concentration of volume percent reaches 60%, stands overnight, collect supernatant, concentrate and recycle second
Alcohol, until extract 1.5g/ml containing drug concentration, filtration, obtain concentrate.
S4：According to parts by weight 1：60 weigh carbomer and purified water, the carbomer are added in purified water under room temperature, leaching
It steeps and stirs to carbomer and be completely dissolved, it is spare.
S5：Acetic acid chlorhexidine is weighed by weight and is added into the concentrate of step S3 and is stirred evenly, stirring is equal
Solution after even is added in the solution obtained by step S4, and triethanolamine solution is added dropwise after stirring evenly by weight, and side is added dropwise
While being stirred until homogeneous gelling material to get the vaginal care gel；
S6：Vaginal care gel loading propeller is dispensed, ethylene oxide sterilizing.
The present embodiment makes since Chinese herbal medicine cordyceps sinensis, pilose antler, Semen Cuscutae, Chinese yam, deer whip and HERBA EPIMEDII being added in formula
The related medicinal herb components obtained in vaginal care gel can be absorbed by genital skin, had kidney tonifying, adjusted menstrual disorder, is therapeutic
Cold and treatment menopausal syndrome remarkable efficacy.
Vaginal care gel described in embodiment 1-6 is in vaginal cleaning, vagina is antibacterial, vagina anti-inflammatory, koro, vaginal mucosa
Injury repair goes to eliminate the unusual smell and restore the application in vagina acid-base balance field, and the vaginal care gel is pushed away from propeller
Enter intravaginal 15-20ml or is uniformly applied at vulva.
Guangdong gynaecology of hospital, to had using 100 of vaginal care gel of the present invention in the patients of colpitis into
Line trace is investigated, and 60 patient's recoveries from illness, in two years without recurrence, 37 patient symptoms mitigate significantly, and total effective rate of the invention is high
Up to 97%, it is good generally to react koro effect, cleaning effect.
Shandong gynaecology of hospital is carried out to being had in colpitis patient using 200 of vaginal care gel of the present invention
In follow-up investigation, 140 patient's recoveries from illness, in two years without recurrence, 56 patient symptoms mitigate significantly, and total effective rate of the invention is high
Up to 98%, it is good generally to react koro effect, cleaning effect.
Specific verification example 1
Wu, female, 46 years old, pruritus vulvue always again and again broke out though not being very serious, rear using the present invention
The vaginal care gel of embodiment 1 is pushed into 12ml with propeller just before going to bed every night, fully recovers after two months, do not recurred in 4 years.
Specific verification example 2
Xue, female, 30 years old, the leucorrhea increasing after the raw son of pregnancy, she selected some washing lotions and gel, but there are no always
Any curative effect, the rear vaginal care gel for using the embodiment of the present invention 2, is pushed into 10ml, after 10 days with propeller just before going to bed every night
Leucorrhea increasing phenomenon disappears, and is not recurred in 3 years.
Specific verification example 3
What certain, female, 33 years old, because operating pressure is big, private life was chaotic, lacks exercise and obtained vaginitis, though there is treatment,
It is always again and again to break out, when serious, haemophilia, the rear vaginal care gel for using the embodiment of the present invention 3, every night just before going to bed
Preceding to be pushed into 15ml with propeller, internal piles disappears substantially after two weeks, fully recovers after two months, does not recur in two years.
Specific verification example 4
Mr. Wang, female, 26 years old, because not noticing that personal hygiene obtained trichomonas infection, she ate medicine for oral administration, and curative effect is very poor, after
Some washing lotions and gel are selected, but one stops using, vaginitis will break out, the rear vaginal care for using the embodiment of the present invention 4
Gel is pushed into 20ml with propeller just before going to bed every night, is stopped using after two weeks, and a Ge Yuehouqu hospitals check, trichomonad is sexy
It contaminates symptom all to disappear, not recur in two years.
More than, it is merely preferred embodiments of the present invention, but the protection domain invented is not limited thereto, it is any ripe
Know those skilled in the art in the technical scope disclosed by the present invention, the change or replacement that can be readily occurred in should all be contained
Lid is within protection scope of the present invention.Therefore, the scope of protection of the invention shall be subject to the scope of protection specified in the patent claim.
Claims (6)
1. a kind of vaginal care gel, which is characterized in that include each component of following parts by weight：10-50 parts of acetic acid chlorhexidine,
45-300 parts of honeysuckle, 0.15-2 parts of peppermint, 40-100 parts of purslane, 100-300 parts of Chinese gall tree, 30-200 parts of climbing groundsel,
10-25 parts of kuh-seng, 30-200 parts of aloe, 10-100 parts of radix scutellariae, 4-10 parts of borneol, 4-10 parts of tocopherol, 20-40 parts of carbomer,
20-40 parts of triethanolamine.
2. vaginal care gel according to claim 1, which is characterized in that include each component of following parts by weight：Vinegar
Sour chlorhexidine 20-40 parts, 100-200 parts of honeysuckle, 0.5-1.5 parts of peppermint, 40-80 parts of purslane, Chinese gall tree 150-200
Part, 80-150 parts of climbing groundsel, 15-20 parts of kuh-seng, 80-160 parts of aloe, 40-100 parts of radix scutellariae, 4-8 parts of borneol, tocopherol 4-8
Part, 20-30 parts of carbomer, 20-30 parts of triethanolamine.
3. vaginal care gel according to claim 2, which is characterized in that include each component of following parts by weight：Vinegar
30 parts of sour chlorhexidine, 150 parts of honeysuckle, 1 part of peppermint, 60 parts of purslane, 175 parts of Chinese gall tree, 115 parts of climbing groundsel, kuh-seng 18
Part, 120 parts of aloe, 100 parts of radix scutellariae, 8 parts of borneol, 8 parts of tocopherol, 25 parts of carbomer, 20 parts of triethanolamine.
4. a kind of preparation method according to claim 1-3 any one of them vaginal care gels, which is characterized in that including such as
Lower step：
S1：Kuh-seng is weighed by weight and the ethyl alcohol that the percent by volume of 6 times of weight is 85%, heating and refluxing extraction two is added
Secondary, about 2h, filters to obtain filtrate every time；
S2：By in step S1 filter residue be added weigh by weight honeysuckle, purslane, Chinese gall tree, climbing groundsel, aloe,
In the mixture of radix scutellariae, borneol and tocopherol, and said mixture is impregnated 3 hours using the purified water of 8 times of weight, after decocting 2h
Simultaneously filter residue is obtained by filtration in extraction decocting liquid, and purified water of the above-mentioned filter residue through 6 times of weight is impregnated 3 hours, decocting liquid is extracted after decocting 2h,
Merge the decocting liquid obtained twice, filtrate is obtained by filtration；
S3：Filtrate in step S2 is concentrated into the 1/5 of original volume, merges with the filtrate in step S1, stir and continuously add
Absolute ethyl alcohol, adjustment ethyl alcohol concentration of volume percent reach 60%, stand overnight, collect supernatant, concentrate and recycle ethyl alcohol, until
Extract 1.4-1.6g/ml containing drug concentration, filtration, obtains concentrate；
S4：According to 1：The weight percent of (50-70) weighs carbomer and purified water, and the carbomer is added under room temperature and purifies
In water, impregnates and stir to carbomer and be completely dissolved, it is spare；
S5：Acetic acid chlorhexidine is weighed by weight and is added into the concentrate of step S3 and stirs evenly, after stirring evenly
Solution be added in the solution obtained by step S4, triethanolamine is added dropwise after stirring evenly by weight, while be added dropwise while stir to
Homogeneous gel shape object is to get the vaginal care gel；
S6：Vaginal care gel loading propeller is dispensed, ethylene oxide sterilizing.
5. it is a kind of according to claim 1-3 any one of them vaginal care gels in vaginal cleaning, vagina is antibacterial, vagina disappears
Prevention and nursing after inflammation, koro, vaginal mucosa injury repair, internal piles, external piles, mixed hemorrhoid, anal fissure, anal-surgery and anti-inflammatory town
Application in pain field.
6. application according to claim 5, which is characterized in that the vaginal care gel is pushed into intravaginal from propeller
15-20ml is uniformly applied at vulva.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810214747.5A CN108452151A (en) | 2018-03-15 | 2018-03-15 | A kind of vaginal care gel |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810214747.5A CN108452151A (en) | 2018-03-15 | 2018-03-15 | A kind of vaginal care gel |
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| CN109771545A (en) * | 2019-03-14 | 2019-05-21 | 盛荣秋实生物技术(广州)有限公司 | A kind of temperature sensitive bacteriostatic gel of intelligence |
| CN110193051A (en) * | 2019-06-12 | 2019-09-03 | 广州梅彭健康科技有限公司 | Bacteriostatic gel and preparation method thereof |
| CN110638872A (en) * | 2019-10-24 | 2020-01-03 | 苏州知时生物科技有限公司 | Plant-based hemorrhoid gel and preparation method thereof |
| CN110840827A (en) * | 2019-12-09 | 2020-02-28 | 北京幸福益生再生医学科技有限公司 | Gynecological antibacterial repair gel and preparation method thereof |
| KR20200048344A (en) * | 2018-10-30 | 2020-05-08 | 주식회사 인스팅터스 | Composition for lubricant |
| CN111434334A (en) * | 2019-01-11 | 2020-07-21 | 李可 | Female gel |
| CN111544577A (en) * | 2020-05-27 | 2020-08-18 | 和携科技有限公司 | Female reproduction nursing preparation and preparation method thereof |
| CN113181336A (en) * | 2021-06-11 | 2021-07-30 | 陕西秦岭七药协同创新中心有限公司 | Traditional Chinese medicine composition and preparation for treating gynecological diseases and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107158125A (en) * | 2017-05-25 | 2017-09-15 | 广西大海阳光药业有限公司 | It is a kind of to be used for gynaecological imflammation, wet preparation itched and preparation method thereof |
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Patent Citations (1)
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| CN107158125A (en) * | 2017-05-25 | 2017-09-15 | 广西大海阳光药业有限公司 | It is a kind of to be used for gynaecological imflammation, wet preparation itched and preparation method thereof |
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| KR20200048344A (en) * | 2018-10-30 | 2020-05-08 | 주식회사 인스팅터스 | Composition for lubricant |
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| CN109771545A (en) * | 2019-03-14 | 2019-05-21 | 盛荣秋实生物技术(广州)有限公司 | A kind of temperature sensitive bacteriostatic gel of intelligence |
| CN110193051A (en) * | 2019-06-12 | 2019-09-03 | 广州梅彭健康科技有限公司 | Bacteriostatic gel and preparation method thereof |
| CN110638872A (en) * | 2019-10-24 | 2020-01-03 | 苏州知时生物科技有限公司 | Plant-based hemorrhoid gel and preparation method thereof |
| CN110840827A (en) * | 2019-12-09 | 2020-02-28 | 北京幸福益生再生医学科技有限公司 | Gynecological antibacterial repair gel and preparation method thereof |
| CN111544577A (en) * | 2020-05-27 | 2020-08-18 | 和携科技有限公司 | Female reproduction nursing preparation and preparation method thereof |
| CN111544577B (en) * | 2020-05-27 | 2022-11-04 | 和携科技有限公司 | Female reproduction nursing preparation and preparation method thereof |
| CN113332348A (en) * | 2021-05-24 | 2021-09-03 | 福建广生健康科技有限公司 | Firming, itching relieving and bacteriostatic gel and preparation method thereof |
| CN113181336A (en) * | 2021-06-11 | 2021-07-30 | 陕西秦岭七药协同创新中心有限公司 | Traditional Chinese medicine composition and preparation for treating gynecological diseases and preparation method and application thereof |
| CN114949025A (en) * | 2022-05-26 | 2022-08-30 | 湖南天济草堂制药股份有限公司 | Senecio scandens gel for treating diabetic foot and nursing after hemorrhoid operation |
| CN114949025B (en) * | 2022-05-26 | 2023-12-22 | 湖南天济草堂制药股份有限公司 | Qianli optical gel for treating diabetic foot and postoperative care of hemorrhoids |
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Application publication date: 20180828 |