CN103251530A - Moderate skin cream containing multiple kinds of pure natural plant extracts - Google Patents
Moderate skin cream containing multiple kinds of pure natural plant extracts Download PDFInfo
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Abstract
The invention discloses a moderate skin cream containing multiple kinds of pure natural plant extracts. A pure natural green tea extract, a liquorice root extract, a rosmarinus officinalis leaf extract, a scutellaria baicalensis root extract, a chrysanthemum extract and a centella asiatica extract are added in raw materials of the skin cream, and all have effects of resisting inflammation and adjusting immunity; the skin cream is capable of completely inhibiting a dozen of inflammatory factors, rapidly stopping skin inflammations caused by various reasons and inhibiting malignant linkage physiological reactions in all stages of the inflammations, has an effect of sephalosprins and is safe without side effects, also has cooperative effects of resisting oxidization, soothing and preserving moisture, and especially has a remarkable clinical effect for nursing of sensitive skin and skin of infants; and the six kinds of selected pure natural plant extracts are added in the skin cream, so that the symptoms such as inflammation and allergies caused by factors such as climate, environment and stimulating substances of the infants can be greatly reduced, the tender and lovely skin of the infants is protected, and thus the moderate skin cream is suitable for being used by the infants.
Description
Technical field
The present invention relates to a kind of protective skin cream.More particularly, specifically refer to a kind of gentle protective skin cream that contains multiple pure natural plant extract.
Background technology
The infant skin resistance against diseases is poor, easily by bacterial infection: because the skin undeveloped mature, so a little less than the function of immune system, can not as the adult, become the first line of defence of human body opposing pathogenic bacterium, only depend on one deck natural acidic film of skin surface to protect skin, be easy to by bacterial infection, anaphylaxis perhaps takes place, as erythema, erythema, blister etc.; Be rich in substrate in the skin connective tissue, water content is higher than the adult, easily being inflamed property edema; A little less than rich blood vessel wherein but was highly brittle simultaneously, stimulated by slight physical property will bleeding due to trauma.Baby's skin only has the thickness of adult skin 1/10th, and epidermis is cell monolayer, and the adult is multi-layer cellular; Collagen fiber in the corium are few, lack flexibility, and are not only easily permeated by foreign object, and cause skin damage because of friction easily.The horny layer of infant skin is undeveloped mature still, and corium and fibrous tissue are thinner, and skin is very young tender, responsive, and the ability of opposing dry environment is more weak.Child's skin is all different with adult's skin on 26S Proteasome Structure and Function.Age is more little, and difference is just more big.Child's skin appearance is level and smooth, delicate, texture is unclear, to external world some physical properties, chemical, mechanicalness, biological invasion and attack resistivity a little less than, therefore, research and develop a suitable baby and use, gentle, as to moisten, do not have allergy, the antiallergic prescription special-purpose skin-protection product of baby is research purpose of the present invention.
Summary of the invention
The invention reside in provides a kind of gentle protective skin cream that contains multiple pure natural plant extract such as Herba Centellae extract, scutellariae,radix extract and green tea extract, and character gentleness, the low stimulation are fit to the baby and use.
Concrete technical scheme of the present invention is as follows:
A kind of gentle protective skin cream that contains multiple pure natural plant extract, the described gentle protective skin cream that contains multiple pure natural plant extract are to be prepared from the conventional method for preparing cream by the following raw material that disposes in proportion:
Emulsifying agent: cetearyl glucoside 1%-3% lauryl alcohol phosphate ester potassium 0.1%-1% cetearyl alcohol 1%-3%
Skin moistening oils and fats: isostearic acid isopropyl ester 3%-4% hydrogenated palm oil glyceride 1%-3% Fructus oleae europaeae fruit oil 1%-3%
Lanoline 0.4%-0.6%
Wetting agent: polyglycereol 4%-10% hyaluronate sodium 0.03%-0.06%
Thickening agent: carbomer 0.15%-0.3%
Antiseptic: methyl hydroxybenzoate and Methylisothiazolinone 0.1%-0.3%
PH value regulator: triethanolamine 0.15%-0.2%
Natural plant extracts: Herba Centellae extract 0.1%--2% scutellariae,radix extract 0.1%--2%
Green tea extract 0.1%--2% Flos Chrysanthemi extracts 0.1%--2% licorice root extract 0.1%--2%
Leaf of Herba Rosmarini Officinalis extract 0.1%--2%;
Described Herba Centellae extract, scutellariae,radix extract, green tea extract, Flos Chrysanthemi extract, licorice root extract is according to conventional chemical or physical chemistry separation method the Herba Centellae after cleaning, scutellariae,radix, green tea, Flos Chrysanthemi, licorice, leaf of Herba Rosmarini Officinalis to be extracted gained, and described Herba Centellae extract, scutellariae,radix extract, green tea extract, Flos Chrysanthemi extract, the relative density of licorice root extract is 0.9-1.1;
Described raw material also comprises: antioxidant: vitamin E 0.15%-0.25% functional additive: allantoin 0.15-0.3%
Skin sense improving agent: polydimethylsiloxane 0.5%-1.5% chelating agen: disodiumedetate 0.04%-0.06%
Surplus is plasma water.
The invention has the advantages that:
The present invention is added with Herba Centellae extract, scutellariae,radix extract, green tea extract, Flos Chrysanthemi extraction, licorice root extract, has antiinflammatory and immunomodulating effect; Can suppress tens kinds of inflammatory factors the most all sidedly, stop fast because the scytitis that a variety of causes (comprising inner reason) causes, the pernicious chain physiological reaction in each stage of inflammation-inhibiting, there are class effects of antibiotics and safety to have no side effect, antioxidation is also arranged simultaneously, the cooperative effect of releiving and preserving moisture especially has obvious clinical effectiveness for allergic skin and infant skin nursing; Can also reduce symptoms such as inflammation that the baby causes because of factors such as weather, environment, pungents, allergy, protect baby's tender and lovely skin.The present invention also has the advantage low and low to the stimulation degree of eyes to the stimulation degree of skin.
The specific embodiment
A kind of preferred embodiment of the present invention:
The water preparation of raw material:
The 72.5Kg deionized water is injected corresponding aqueous phase reactions still, turn on agitator, the rotating speed of employing 50/min slowly is sprinkled into the 0.2Kg carbomer in the kettle, stirs 2 hours to transparent fully, is heated to 80-85 ℃ of degree and maintenance.Continue then
Stirring also adds 0.05Kg disodiumedetate, 8Kg polyglycereol-10,0.5Kg lauryl alcohol phosphate ester potassium, 0.05Kg
Hyaluronate sodium maintains the temperature at 80 ℃-85 ℃, stops after the water raw material is dissolved fully stirring and heating.
The oil phase preparation of raw material:
2.5Kg cetearyl glucoside, 4.0Kg isostearic acid isopropyl ester, 2.5Kg cetearyl alcohol, 0.1Kg methyl hydroxybenzoate, 2.0Kg hydrogenated palm oil glyceride, 2.0Kg Fructus oleae europaeae fruit oil, 0.2Kg vitamin E, 0.5Kg lanoline, 1.0Kg polydimethylsiloxane are successively dropped in the corresponding oil phase reactor, begin heating then, open when reaching certain mobile shape and stir, heat while stirring, slowly be heated to 80 ℃-85 ℃, make to stop when raw material dissolves fully in the oil phase stirring and heating.
Mixing and emulsifying:
Open the vacuum system of vacuum emulsification pot, make the vacuum emulsification pot be in the vacuum state of vacuum-0.07MPa, water is mixed
The raw material and the raw material in the oil phase reactor that close in the heating and stirring pot suck in the emulsifying pot by vacuum, keep the interior temperature of vacuum emulsification pot to open vacuum emulsification pot agitator then at 80 ℃-85 ℃ and carry out the homogenizing stirring, homogenizing speed of agitator 2500r/min stirs 3min.
After homogenizing stirs and to finish, adopt the rotating speed of 50R/min to continue to stir, and open vacuum system, make in the vacuum emulsification pot vacuum be-0.06MPa, keep in the vacuum emulsification pot that emulsifying temperature kept 30 minutes more than 80 ℃.
Add natural plant extracts:
Open vacuum emulsification pot cooling water valve, allow the interior emulsion of vacuum emulsification pot slowly lower the temperature, add the 0.2Kg triethanolamine simultaneously and regulate pH value. when material temperature drop to 45 ℃, open the vacuum valve of vacuum emulsification pot, 0.2 Kg allantoin, 0.4Kg Herba Centellae extract, 0.4Kg scutellariae,radix extract, 0.4Kg green tea extract, 0.4Kg Flos Chrysanthemi extract, 0.4Kg licorice root extract, 0.4Kg leaf of Herba Rosmarini Officinalis extract, 0.1Kg Methylisothiazolinone are added the vacuum emulsification pot.Continue then to stir 15 minutes.
Discharging:
Continue to stir cooling, open the vacuum system of vacuum emulsification pot simultaneously, make the vacuum emulsification pot be in the vacuum state of vacuum-0.07MPa.Bubble in the material is extracted.When material temperature drop to 35 ℃, the vacuum that stops to stir and putting the vacuum emulsification pot, discharging obtains containing the gentle protective skin cream of multiple pure natural plant extract.
The present invention (acute) skin irritation test:
At relative humidity 60-70%, under ambient temperature 20-24 ℃ the condition, the protective skin cream that above method is made spreads upon on one's body the Cavia porcellus of four body weight 250g-300g, observes a week continuously, and every day, phenomenons such as erythema, edema did not all appear in every Cavia porcellus.Through Fujian dream Guerlain day the chemicals company limited entrust the Shanghai institute of Pharmaceutical Industry to test with regard to (acute) skin irritation of product, this protective skin cream is spread upon on one's body the Cavia porcellus of four body weight 250g-300g, four Cavia porcelluss of smearing protective skin cream are at relative humidity 60-70%, one week of life under ambient temperature 20-24 ℃ the condition, after testing, every day, phenomenons such as erythema, edema did not all appear in every Cavia porcellus; Stimulus intensity is classified as: do not see irritative response.
Experimental result shows that the present invention is low to the stimulation degree of skin.
The stimulation test of human body eyes of the present invention:
The protective skin cream that above method is made is diluted to the solution of 10 ﹪, and it is maintained 37-38 ℃, this test material is added drop-wise to gradually in tester's the eye, sterile pure water is added drop-wise to gradually in tester's the another eye then.This research needs 10 testers.
Test according at random inferior ordered pair tester, and the material of specifying which kind of material which eye is dripped and drips also is to carry out in mode at random.A suitable test fluid is added drop-wise to first eye of tester at leisure, then sterile water is added drop-wise at leisure second eye.
In 30 seconds, or as quickly as possible after dripping test material, the inquiry tester, utilize following standard to they the eyes irriate feel carry out classification: 0=is within normal limit; The 1=gentleness, very slight stimulation; The medium stimulation of 2=; Seriously stimulate with 3=.Dripping test material after 1/4 hour and 1 hour, inquire the tester again, classification is carried out in the stimulation of eyes.
Carry out the eye irritation test of human body with the compositions that makes.The result of research is as shown in the table.
| The test group | Sample | Grade to eye irritation | Sample | Grade to eye irritation |
| 1 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
| 2 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
| 3 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
| 4 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
| 5 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
| 6 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
| 7 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
| 8 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
| 9 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
| 10 | Protective skin cream is diluted to the solution of 10 ﹪ | 0 | Sterile pure water | 0 |
Test result shows that compositions of the present invention is more serious to the stimulation of eyes unlike sterile pure water.
Green tea contains flavonoid, and catechin, catechin are a kind of effective anti-infectives.And what content was maximum in the green tea is tea polyphenols, is rich in phenolic hydroxyl group in the tea polyphenols structure, and active hydrogen can be provided, and makes the free radical deactivation, and the free radical of oxidized formation own is owing to the catechol structure has advantages of higher stability.Therefore tea polyphenols has the effect of removing free radical and suppressing lipid peroxidation.
Radix Glycyrrhizae has good whitening function, has the title of " queen whitens ", the activity of the anti-ultraviolet while restraint of tyrosinase of Radix Glycyrrhizae extract, and can also improve the skin of coarse, hydropenia, inflammation, be a kind of multi-functional plant of whitening; Secondly, Radix Glycyrrhizae has stronger antiinflammatory and the effect of resistance attitude, and is better than sulfanilamide and antibiotic drug effect; Moreover Radix Glycyrrhizae has the effect of antioxidation and free radical resisting preferably.
A kind of material that is carnosol is arranged in the Herba Rosmarini Officinalis, and its moistening effect is remarkable.Experiment shows, smear skin after two weeks with the astringent that contains this material, the moisture of skin can rise to 63% from 44%, and water evaporation quantity then drops to below 13% from 21%, just as increased by one the natural cover for defense to skin, reduced a lot because the skin problem that hydropenia causes.
Radix Scutellariae has antioxidation, anticancer, antiviral, pharmacological action such as antibiotic; Have effects such as heat clearing and damp drying, eliminating fire and detoxication.
Flos Chrysanthemi is common plant, and energy wind and heat dispersing, suppressing the hyperactive liver make eye bright its main component position volatile oil, flavonoid and aminoacid, trace element etc.Flos Chrysanthemi extract can influence the permeability of blood capillary, increases capillary resistance, therefore has significant antiinflammatory action; Secondly, Flos Chrysanthemi extract has tangible refrigeration function; Moreover Flos Chrysanthemi extract also has anti-aging effects.
Herba Centellae extract has the effect of outstanding healing of wound and cicatrix reparation, and its reason is that asiaticoside has the synthetic and important function such as neovascularity generation, the growth of stimulation granulation of collagen in the promotion, so be conducive to wound healing.Herba Centellae extract also has stronger antioxidation, can suppress free radical activity, and the desalination melanin pigmentation improves the skin blood circulation, upgrades skin cell regeneration, helps the smooth metabolism of melanin to go out external.
These the six kinds selected plant extracts that come out all can show antiinflammatory and immunomodulating effect; Can suppress tens kinds of inflammatory factors the most all sidedly, stop fast because the scytitis that a variety of causes (comprising inner reason) causes, the pernicious chain physiological reaction in each stage of inflammation-inhibiting, there are class effects of antibiotics and safety to have no side effect, antioxidation is also arranged simultaneously, the cooperative effect of releiving and preserving moisture especially has obvious clinical effectiveness for allergic skin and infant skin nursing.In this protective skin cream, add these six kinds of selected pure natural plant extract and can reduce symptoms such as inflammation that infant causes because of factors such as weather, environment, pungents, allergy greatly, protected the tender and lovely skin of infant.
Claims (1)
1. gentle protective skin cream that contains multiple pure natural plant extract is characterized in that: the described gentle protective skin cream that contains multiple pure natural plant extract is that the raw material by following configuration in proportion is prepared from the method that routine prepares cream:
Emulsifying agent: cetearyl glucoside 1%-3% lauryl alcohol phosphate ester potassium 0.1%-1% cetearyl alcohol 1%-3%
Skin moistening oils and fats: isostearic acid isopropyl ester 3%-4% hydrogenated palm oil glyceride 1%-3% Fructus oleae europaeae fruit oil 1%-3%
Lanoline 0.4%-0.6%
Wetting agent: polyglycereol 4%-10% hyaluronate sodium 0.03%-0.06%
Thickening agent: carbomer 0.15%-0.3%
Antiseptic: methyl hydroxybenzoate and Methylisothiazolinone 0.1%-0.3%
PH value regulator: triethanolamine 0.15%-0.2%
Natural plant extracts: Herba Centellae extract 0.1%--2% scutellariae,radix extract 0.1%--2%
Green tea extract 0.1%--2% Flos Chrysanthemi extracts 0.1%--2% licorice root extract 0.1%--2%
Leaf of Herba Rosmarini Officinalis extract 0.1%--2%;
Described Herba Centellae extract, scutellariae,radix extract, green tea extract, Flos Chrysanthemi extract, licorice root extract is according to conventional chemical or physical chemistry separation method the Herba Centellae after cleaning, scutellariae,radix, green tea, Flos Chrysanthemi, licorice, leaf of Herba Rosmarini Officinalis to be extracted gained, and described Herba Centellae extract, scutellariae,radix extract, green tea extract, Flos Chrysanthemi extract, the relative density of licorice root extract is 0.9-1.1;
Described raw material also comprises: antioxidant: vitamin E 0.15%-0.25% functional additive: allantoin 0.15-0.3%
Skin sense improving agent: polydimethylsiloxane 0.5%-1.5% chelating agen: disodiumedetate 0.04%-0.06%
Surplus is plasma water.
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| CN107184410A (en) * | 2017-04-28 | 2017-09-22 | 广州瑞誉化工科技有限公司 | A kind of skin cream with steroid dependent dermatitis repair function |
| CN107184448A (en) * | 2017-04-28 | 2017-09-22 | 广州瑞誉化工科技有限公司 | A kind of acne eliminating cream that there is prevention pockmark to generate |
| CN107184485A (en) * | 2017-07-06 | 2017-09-22 | 福建省海乐威生物工程有限公司 | A kind of jasmine hot spring face cream with repair |
| CN107320565A (en) * | 2017-07-19 | 2017-11-07 | 珠海伊斯佳科技股份有限公司 | A kind of Chinese medicine composition with antiallergic sense effect and its preparation method and application |
| CN107929146A (en) * | 2017-12-19 | 2018-04-20 | 武汉北度生物科技有限公司 | A kind of anti-oxidant face cream of the extract component containing cauliflower and preparation method thereof |
| CN108464968A (en) * | 2018-05-22 | 2018-08-31 | 广东药科大学 | A kind of infant's anti-inflammatory cream and preparation method thereof |
| CN108703930A (en) * | 2018-08-26 | 2018-10-26 | 福建乐伴护理用品有限公司 | A kind of moisturiser and preparation method thereof containing Abelmoschus Esculentus Linn extract |
| CN109793688A (en) * | 2019-03-30 | 2019-05-24 | 福建省梦娇兰日用化学品有限公司 | A kind of resistant to pollution infant's cleaning compositions of moisturizing and preparation method thereof |
| CN110433116A (en) * | 2019-08-27 | 2019-11-12 | 广东锦玛绿色食品科技有限公司 | One kind containing the anti-inflammatory Deacne pack of natural component |
| CN110638673A (en) * | 2019-09-25 | 2020-01-03 | 河北瑞龙生物科技有限公司 | Skin care product containing green tea extract and preparation method thereof |
| CN110693742A (en) * | 2019-10-12 | 2020-01-17 | 福建省梦娇兰日用化学品有限公司 | Infant moisturizing cream prepared by using microfiltration, concentration and extraction technology |
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| CN103251530B (en) | 2015-06-17 |
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Address after: 363104 No.8, Shugang Road, Fugong Town, Longhai City, Zhangzhou City, Fujian Province Patentee after: FUJIAN MENGJIAOLAN DAILY CHEMICALS Co.,Ltd. Address before: 363118 Fujian, Zhangzhou City, Longhai province Yan Town Industrial Development Zone Patentee before: FUJIAN MENGJIAOLAN DAILY CHEMICALS Co.,Ltd. |
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Denomination of invention: A skin cream containing plant extracts Effective date of registration: 20220614 Granted publication date: 20150617 Pledgee: Bank of China Limited Longhai sub branch Pledgor: FUJIAN MENGJIAOLAN DAILY CHEMICALS Co.,Ltd. Registration number: Y2022350000061 |