CN107184410A - A kind of skin cream with steroid dependent dermatitis repair function - Google Patents
A kind of skin cream with steroid dependent dermatitis repair function Download PDFInfo
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- CN107184410A CN107184410A CN201710300396.5A CN201710300396A CN107184410A CN 107184410 A CN107184410 A CN 107184410A CN 201710300396 A CN201710300396 A CN 201710300396A CN 107184410 A CN107184410 A CN 107184410A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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Abstract
The invention discloses a kind of skin cream with steroid dependent dermatitis repair function, at least containing a kind of plant extracts that there is activation epidermal basal cell to divide effect；At least the plant extracts of the required nutrition of epidermal basal cell growth can be provided containing a kind of；At least strengthen the plant extracts of epidermal barrier function containing a kind of；At least there is the plant extracts of notable antiallergic effect containing more than one；At least contain a kind of significant natural extract of moistening effect；At least containing a kind of plant extracts with healing of wound and scar repair, in addition, it also includes emulsifying agent, pure plant grease, NMF, thickener, preservative, chelating agent and deionized water；There is the skin cream of steroid dependent dermatitis repair function to be prepared into liquid crystal emulsified system as emulsifying agent using hydrolecithin for this, there is good shield effectiveness to skin, be conducive to the infiltration of active ingredient again, while being also equipped with good moistening effect and product use feeling.
Description
Technical field
The present invention relates to a kind of skin cream with steroid dependent dermatitis repair function.
Background technology
In recent years, the illegal phenomenon for adding hormone in both effectiveness cosmetics, of common occurrence.For example：In whitening spot-removing production
" quinhydrones+vitamin A acid+dexamethasone " or " ammoniated mercury+dexamethasone " is used in product；" chloramphenicol+ground is used in product for resolving poxes
Sai meter Song "；Use and combined the effects such as " dexamethasone or betamethasone " in anti-anaphylaxis product.What is more, to reduce the mistake of product
Quick reaction, or even all add sugar skin hormone in common cosmetics.Particularly in recent years, the addition " chlorine times in mask product
" a note fine flour film " volume of production and marketing of his rope class " increases again in geometry, causes steroid dependent dermatitis morbidity to rise year by year, obstinate difficult
Cure.
Hormone, which is used for a long time, will trigger steroid dependent dermatitis.Steroid dependent dermatitis refer to because it is prolonged and repeated improperly
Dermatitis caused by external application hormone.Show as primary skin damaged after external application glucocorticoid to disappear, but inflammatory damage occur again after deactivation,
A kind of dependence facial dermatitis that Reusability glucocorticoid is needed to control symptom and gradually aggravate.
Sugar skin hormone can suppress the metabolism of skin, slow down basal cell division speed, melanocyte secretes black
Pigment is reduced, the lipid of cuticula and protein metabolism are substantially at repressed state.That is, only old cuticula
Peel off, supplemented without new corneocyte, in the course of time, keratoderma is with regard to more and more thinner, when serious, and skin is exactly simply
" running nakedly ".
The content of the invention
In view of this, liquid crystal emulsified body is prepared into as emulsifying agent using hydrolecithin it is an object of the present invention to provide one kind
System, there is good shield effectiveness to skin, be conducive to the infiltration of active ingredient again, while be also equipped with good moistening effect and
The skin cream with steroid dependent dermatitis repair function of product use feeling.
In order to solve the above-mentioned technical problem, the technical scheme is that：
A kind of skin cream with steroid dependent dermatitis repair function, includes the raw material of following percentage by weight：Hydrogenation
Lecithin 1.5%, laruyl alcohol phosphate potassium 0.3%, camellia seed oil 6.0%, evening primrose oil 4.0%, cetostearyl alcohol 2.5%,
Olive oil 2.0%, vitamin E 0.2%, phytosterols oletate 0.5%, dimethyl silicone polymer 1.0%, ethylenediamine
Tetraacethyl disodium 0.05%, Natrulon H-10 8.0%, carbomer 0.2%, arginine 0.2%, Sodium Hyaluronate 0.05%, open country
Soybean Peptide 0.3-0.5%, bluish-green microalgae extract 1.5-2.5%, the yeast product 0.5-1.5% of soybean, glycyrrhiza glabra root
Extract 0.2-0.8%, purslane extract 0.5-1.5%, carbohydrate isomer 3.0-5.0%, Gotu Kola P.E
0.3-0.8%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
Further, the raw material of following percentage by weight is included：Hydrolecithin 1.5%, laruyl alcohol phosphate potassium
0.3%th, camellia seed oil 6.0%, evening primrose oil 4.0%, cetostearyl alcohol 2.5%, olive oil 2.0%, vitamin E
0.2%th, phytosterols oletate 0.5%, dimethyl silicone polymer 1.0%, disodium ethylene diamine tetraacetate 0.05%, polyglycereol-
10 8.0%, carbomer 0.2%, arginine 0.2%, Sodium Hyaluronate 0.05%, Wild soybean peptide 0.3%, bluish-green microalgae are extracted
Thing 1.5%, the yeast product 0.5% of soybean, glycyrrhiza glabra root extract 0.2%, purslane extract 0.5%, carbohydrate are same
Enantiomers 3.0%, Gotu Kola P.E 0.3%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
Further, the raw material of following percentage by weight is included：Hydrolecithin 1.5%, laruyl alcohol phosphate potassium
0.3%th, camellia seed oil 6.0%, evening primrose oil 4.0%, cetostearyl alcohol 2.5%, olive oil 2.0%, vitamin E
0.2%th, phytosterols oletate 0.5%, dimethyl silicone polymer 1.0%, disodium ethylene diamine tetraacetate 0.05%, polyglycereol-
10 8.0%, carbomer 0.2%, arginine 0.2%, Sodium Hyaluronate 0.05%, Wild soybean peptide 0.5%, bluish-green microalgae are extracted
Thing 2.5%, the yeast product 1.5% of soybean, glycyrrhiza glabra root extract 0.8%, purslane extract 1.5%, carbohydrate are same
Enantiomers 5.0%, Gotu Kola P.E 0.8%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
Further, the raw material of following percentage by weight is included：Hydrolecithin 1.5%, laruyl alcohol phosphate potassium
0.3%th, camellia seed oil 6.0%, evening primrose oil 4.0%, cetostearyl alcohol 2.5%, olive oil 2.0%, vitamin
E0.2%, phytosterols oletate 0.5%, dimethyl silicone polymer 1.0%, disodium ethylene diamine tetraacetate 0.05%, polyglycereol-
10 8.0%, carbomer 0.2%, arginine 0.2%, Sodium Hyaluronate 0.05%, Wild soybean peptide 0.4%, bluish-green microalgae are extracted
Thing 2.0%, the yeast product 1.0% of soybean, glycyrrhiza glabra root extract 0.5%, purslane extract 1.0%, carbohydrate are same
Enantiomers 4.0%, Gotu Kola P.E 0.55%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
Principle explanation：
Preparation method：
Foregoing skin care compositions can by by required composition in suitable container, at ambient conditions
Its mixing is prepared, any conventional mixing apparatus well known in the art can be used during preparation, such as：Emulsifying homogeneous pot etc., is mixed
Needed during conjunction the molten and water-soluble difference Hybrid Heating of oil to 80 DEG C, then oil phase is mixed with water conjunction stirring homogeneous, cools to
Innate efficacy thing is added at 45 DEG C.
The technology of the present invention effect major embodiment is in the following areas：The present invention is prepared into liquid using hydrolecithin as emulsifying agent
Brilliant emulsification system, this system has same epidermis extremely similar structure, has good shield effectiveness to skin, is conducive to again
The infiltration of composition is imitated, while being also equipped with good moistening effect and product use feeling, last layer is worn equivalent to fragile epidermis
Soft coat；In addition, a kind of gentle face cream containing a variety of pure natural plant extracts of the present invention meets through examining
National sector standard, its indices comply fully with sanitary quality standard and the security requirement of national regulation.
Embodiment
With reference to embodiments, the embodiment to the present invention is described in further detail, so that technical solution of the present invention
It is more readily understood and grasps.
Embodiment 1
A kind of skin cream with steroid dependent dermatitis repair function, includes the raw material of following percentage by weight：Hydrogenation
Lecithin 1.5%, laruyl alcohol phosphate potassium 0.3%, camellia seed oil 6.0%, evening primrose oil 4.0%, cetostearyl alcohol 2.5%,
Olive oil 2.0%, vitamin E 0.2%, phytosterols oletate 0.5%, dimethyl silicone polymer 1.0%, ethylenediamine
Tetraacethyl disodium 0.05%, Natrulon H-10 8.0%, carbomer 0.2%, arginine 0.2%, Sodium Hyaluronate 0.05%, open country
Soybean Peptide 0.3%, bluish-green microalgae extract 1.5%, the yeast product 0.5% of soybean, glycyrrhiza glabra root extract 0.2%,
Purslane extract 0.5%, carbohydrate isomer 3.0%, Gotu Kola P.E 0.3%, glycerol caprylate 0.2%, decoyl
Hydroximic acid 0.3%, surplus are water.
Embodiment 2
A kind of skin cream with steroid dependent dermatitis repair function, includes the raw material of following percentage by weight：Including
The raw material of following percentage by weight：Hydrolecithin 1.5%, laruyl alcohol phosphate potassium 0.3%, camellia seed oil 6.0%, oenothera biennis
It is oil 4.0%, cetostearyl alcohol 2.5%, olive oil 2.0%, vitamin E 0.2%, phytosterols oletate 0.5%, poly-
Dimethyl siloxane 1.0%, disodium ethylene diamine tetraacetate 0.05%, Natrulon H-10 8.0%, carbomer 0.2%, arginine
0.2%th, Sodium Hyaluronate 0.05%, Wild soybean peptide 0.5%, bluish-green microalgae extract 2.5%, the yeast product of soybean
1.5%th, glycyrrhiza glabra root extract 0.8%, purslane extract 1.5%, carbohydrate isomer 5.0%, centella are extracted
Thing 0.8%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
Embodiment 3
A kind of skin cream with steroid dependent dermatitis repair function, includes the raw material of following percentage by weight：Including
The raw material of following percentage by weight：Hydrolecithin 1.5%, laruyl alcohol phosphate potassium 0.3%, camellia seed oil 6.0%, oenothera biennis
It is oil 4.0%, cetostearyl alcohol 2.5%, olive oil 2.0%, vitamin E 0.2%, phytosterols oletate 0.5%, poly-
Dimethyl siloxane 1.0%, disodium ethylene diamine tetraacetate 0.05%, Natrulon H-10 8.0%, carbomer 0.2%, arginine
0.2%th, Sodium Hyaluronate 0.05%, Wild soybean peptide 0.4%, bluish-green microalgae extract 2.0%, the yeast product of soybean
1.0%th, glycyrrhiza glabra root extract 0.5%, purslane extract 1.0%, carbohydrate isomer 4.0%, centella are extracted
Thing 0.55%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
Principle explanation：
The first composition of the present invention is at least to be carried containing a kind of plant that there is activation epidermal basal cell to divide effect
Take thing：Wild soybean peptide, therefore the currently preferred plant extracts that there is activation epidermal basal cell to divide effect is pure day
Right Wild soybean peptide.
Second of composition of the present invention is at least to provide the plant of the required nutrition of epidermal basal cell growth containing a kind of
Extract：AFA algaes are thread wild algae plants, it is impossible to artificial culture, are grown on the carat of Ore.
Outside the AFA algaes in this lake (Klamath Lake) of agate, isolating protein, carbohydrate, mineral matter, aliphatic acid and chlorophyll, in AFA
In main nutritional ingredient also include：The precursor --- beta carotene), superoxide dismutase (SOD) --- of vitamin A
A kind of important antioxidant of highly effective antioxidant, glutathione --- skin anti-light aging, vitamin B complex (B1,
B2, B3, B5, B6, B7, B9, B12), essential fatty acid (leukotrienes and gamma-Linolenic acid), eight kinds of essential amino acids of needed by human body
And vitamin C and vitamin E.Therefore it is currently preferred have trophic function needed for epidermal basal cell growth can be provided
It is the bluish-green microalgae extract being grown in the U.S. carat this lake of agate.
The third composition of the present invention at least strengthens the natural extract of epidermal barrier function containing a kind of：The U.S.
The DermalRx Hydroseal of Biocogent productions, are obtained by the biological fermentation process of the yeast strain of patent,
DermalRx HydroSeal main active has the oligopeptides and soy-derived amino acid of yeast, the outermost of epidermis
Layer is the protective barrier being joined together to form by keratinocyte layer, and the albumen of cornea chain albumen (CD) is referred to as to skin one kind
Matter by connecting flanking cell angling desmosome between it is healthy most important.
It is to be linked together by a kind of assembly for being referred to as angling desmosome between horn cell.
Different CD molecules, can be effectively sealing off flanking cell, and experimental study proves that DermalRx Hydroseal are effective
The affinity of energy horn cell film film chain albumen is improved there is provided structure moisturizing activity, firm cell connection is rebuild, so as to have
Help recover skin natural moisture preserving ability, thus it is currently preferred with a kind of plant extracts of enhancing epidermal barrier function
It is the yeast product of soybean --- DermalRx Hydroseal.
The 4th kind of composition of the present invention is the plant extracts with notable antiallergic effect：Radix glycyrrhizae contain it is a variety of chemistry into
Point, main component has glycyrrhizic acid, liquiritin etc..The chemical composition of radix glycyrrhizae is extremely complex, is isolated so far from radix glycyrrhizae
Compound has glycyrrhizin, enoxolone, liquiritin, isoliquiritin, neoliquriitin, neoisoliquiritin, glycyrrhizin, isoliquiritigenin
And the tens of kinds of compounds such as licoricidin, glycyrol, isoglycyrol, 7- methylcoumarins essence, umbelliferone；Radix glycyrrhizae have compared with
Strong anti-inflammatory and anti-metamorphosis, the drug effect than sulfanilamide (SN) and antibiotic are good；Furthermore, radix glycyrrhizae has preferably anti-oxidant and resisted certainly
By the effect of base；Purslane contains substantial amounts of norepinephrine (containing 0.25% in fresh purslane), neurohormone (tool
Have and play vessel retraction effect, hypotension and the function of reducing tissue bleeding), purslane is also containing many common nutrients
(concentration is from low to high), including：Vitamin (vitamin A, vitamin B1, vitamin B2, vitamin C, niacinamide, cigarette
Acid, (- tocopherol, (- carotene etc.), mineral matter particularly potassium, aliphatic acid (particularly leukotrienes, i.e. Ω -3, it is in purslane
In concentration be highest in all leafy plants), glutathione, glutamic acid and aspartic acid；Other compositions are included by one
Mucus, calcium oxalate, malic acid and citric acid, dopamine and DOPA, perfume (or spice) that the acid and neutrals of part known structure are constituted
Other useful materials such as legumin, flavonoids, saponin and urea.Whole plant contains carotene；Vitamin C, B1, B2,
PP；Ca, Mg, Na, K salt；Organic acid；Cigarette (alkali) acid and oxalic acid；Norepinephrine and bisflavones liquiritin.In world wide
Interior this plant is eaten as salad or vegetables, and can be used to treat a variety of diseases, including headache, stomach as medicinal material
Bitterly, painful urination, enteritis, mastitis, puerpera's milk deficiency and postpartum haemorrhage.External application then can be used for treatment burn, otalgia, elder brother
Sting, inflammation, cutaneous pain, ulcer, itch (skin is itched) eczema and abscess.Purslane extract is had been developed that as change
The active matter of anti-inflammatory, anti-irritant and antiallergic in cosmetic, therefore, the currently preferred plant extract with notable antiallergic effect
Thing is glycyrrhiza glabra root extract, purslane extract.
The 5th kind of composition of the present invention is that at least have the significant composition of moistening effect containing a kind of：Carbohydrate isomerism
Body (saccharide isomerate) is colourless or micro- yellow transparency liquid, a kind of natural guarantor of extraction from sugarcane carbohydrate synthesis
Humectant, assists the keratin in moisture content combined with stratum corneum, with up to moistening effect.It is a kind of good water-loss reducer and emollients.Tool
Have reparation epidermal layer cells, lifting skin moisturizing ability, the isomerization D- glucans manufactured via Measurement for Biochemistry, with
The close composition structure of human keratinous layer, can be combined with epsilon-amino acid functional group using on skin, firmly be tied just as magnetite
Close, long-acting can maintain the hydromagnetic field energy power of skin.Therefore be known as again：Water lock magnetite, its main component is：Glucose, fruit
Sugar, lactose, lactose product, mannose, galactolipin, psicose.Therefore, it is currently preferred that there is significant group of moistening effect
Compound is carbohydrate isomer.
The 6th kind of composition of the present invention is at least containing a kind of plant wherein with healing of wound and scar repair
Extract：Centella contains a variety of triterpenes, wherein including α-amyrin structure.Main component is Asiaticoside, centella
Acid and brahmic acid.Found by the scientific researches of more than 20 years, Gotu Kola P.E can promote collagen I and III
Synthesis, while can also promote the secretion (synthesis of such as hyaluronic acid) of mucopolysaccharide, increases the water conservation degree of skin, activation updates skin
Cell, makes skin releive, be lifted and rich in reflecting feel；On the other hand testing research is arranged by cDNA and also found that centella carries
Take thing that also there is the activation of fibroblast gene, can strengthen the vigor of skin basal layer cell, keep elasticity of skin and
Consolidation sense, smooth face's fine wrinkles.By experiment, it was also found that making using the asiaticosid and madecassoside of various dose
After fibroblast. in vitro culture (HumanSkinFibroblast, HSFb), pass through the method determination experiment of radio-immunity
I procollagen type aminoterminals peptide former (P I NP) and type III precollagen aminoterminal peptide former in group and blank control group cell supernatant
(PIII NP) content.As a result show：1. compared with blank control group, asiaticosid and madecassoside can effective stimulus bodies
Outer culture HSFbP I NP and P III NP secretion；2. asiaticosid and madecassoside stimulate target cell P I NP and P
Obvious dose-effect relationship is presented in the biological action of III NP secretions；3. in the μ g/mL dosage of 10 μ g/mL~150, Ad is to HSFb
P I NP secretion is stimulated to show the bioactivity more stronger than Md；Therefore, it is currently preferred that there is healing of wound and scar
The plant extracts of repair is Gotu Kola P.E.
This six kinds are chosen the natural function composition come, formation mechenism and the disease of affected skin from steroid dependent dermatitis
Shape is set about, and takes " from outside to inside ", " by mark to originally ", and the maintenance scheme of multipath gives compromised skin to add protective filmy layer, resistance
Every environmental stimuli.The skin cuticula of suffering from steroid dependent dermatitis is thinning, skin fragility, it is therefore desirable to injured skin addition one
Layer closing " coat ", stimulation of the barrier outside contamination environment to skin, prevents water loss in skin.
" substitute " that naturally has no side effect of hormone is found, skin " drug addiction " is given up.The skin of steroid dependent dermatitis,
Once departing from hormone is easy to occur the symptoms such as allergy, inflammation.At this moment it is accomplished by " to substitute using a kind of product of antiallergic anti-inflammatory
" hormone.Prevent such skin from occurring allergic reaction.
Repair stratum corneum barrier function.For from the basic skin for solving the problems, such as steroid dependent dermatitis, it is desired nonetheless to by
The health for hindering skin is re-established, and becomes the skin of normal vital.First have to repair the barrier function of cuticula.
Epidermal barrier " brick wall structure " theory image indicate importance of the epidermis in skin function." wall brick " represents cutin and formed carefully
Born of the same parents；" mortar " then refers to lipid (containing ceramide, aliphatic acid, cholesterol etc.) between horn cell, and " wall brick " and " mortar " makes epidermis
Firm structure is formed, the volatilization of moisture of skin is limited, the water content of skin, thorn of the barrier external environment to delicate skin is kept
Swash." wall brick " can not be implemented in cosmetic field, and our impetus supplements rational proportion in the product at " mortar "
The compositions such as " cement " --- phytosterol, ceramide, phosphatide and aliphatic acid.
The healthy merisis of fast quick-recovery basal cell.It is well known that whole epidermal tissue is by epidermal basal cell
Merisis is formed, and accelerates to recover the division of epidermal basal cell and growth to the skin gesture of maintenance steroid dependent dermatitis must
OK.By using " EGF " or the composition of " have and promote the division of epidermis flesh floor cells and growth ", to stimulate substrate
Cell division growth；The nutritional ingredient needed for cell fast-growth is added again there is provided the enough nutrition needed for epidermal growth,
Accelerate the Quick-return of whole epidermis.
Foregoing skin care compositions can by by required composition in suitable container, at ambient conditions
Its mixing is prepared, any conventional mixing apparatus well known in the art can be used during preparation, such as：Emulsifying homogeneous pot etc.；It is mixed
Needed during conjunction the molten and water-soluble difference Hybrid Heating of oil to 80 DEG C, then oil phase is mixed with water conjunction stirring homogeneous, cools to
Innate efficacy thing is added at 45 DEG C.
Object and method
Object
Take random, open, Self-controlled study.Choose Hubei Jianghan Oil-field central hospital hormone accordance with tolerance dermatitis patients
42 altogether.Wherein male patient 7, female patient 35, max age 51 years old, minimal ages 18 years old.All patient's voluntary participations
Clinical observation, signs informed consent form, and promise uses the steroid dependent dermatitis repair cream on request.
Inclusion criteria：1. unused glucocorticoid exterior-applied article etc. in 2 weeks before clinical observation, and during observing without using
Said medicine；2. do not indulged in excessive drinking during observing, excessive maror is not eaten.
Treatment method
Treatment group is cleaned behind affected part with clear water, is uniformly smeared the repair cream, twice daily, is used in conjunction 2 weeks.
Control group is cleaned behind affected part with clear water, with up to inner Podbielniak liquid (the conventional hormone of zinc sulfate and copper-bath-hospital
The non-hormone medicine of dependence facial dermatitis) affected part is smeared, twice daily, it is used in conjunction 2 weeks.
Outcome measure
It is effective：Treat after 2 weeks, symptom disappears, pigmented spots and telangiectasis are only stayed in deflorescence more than 70%.Have
Effect；Symptom mitigation, Schultz-Charlton is less than 70%, more than 50%.It is invalid：Schultz-Charlton is less than 50%, and symptom mitigation is not obvious.
As a result
Effective 8 of Liang Zhouhou treatment groups, effective 10, invalid 3, total effective rate is up to 85.7%；Effective 2 of control group,
Effective 8, invalid 11, as a result effective percentage 47.6% shows, there were significant differences for two groups of clinical effective rates (P ＜ 0.05), explanation
Treatment group is better than control group.Treatment group's no side effects.
The treatment group of table 1 and 2 weeks comparitive studies of control group.
Through examining, there were significant differences for two groups of curative effects (X2=13.091P ＜ 0.05)
2.2 adverse reaction
During steroid dependent dermatitis repair cream, there is a patient for treating 1 month in hospital dermatology department, go out
Existing malaise symptoms, remaining does not occur adverse reaction, and patient's reflection steroid dependent dermatitis repair cream skin sense is good, without excitant
With discomfort sensation, all patients complete whole experiment.
Result of study shows that steroid dependent dermatitis repair cream effective percentage is 90%.
The technology of the present invention effect major embodiment is in the following areas：The present invention is prepared into liquid using hydrolecithin as emulsifying agent
Brilliant emulsification system, this system has same epidermis extremely similar structure, has good shield effectiveness to skin, is conducive to again
The infiltration of composition is imitated, while being also equipped with good moistening effect and product use feeling, last layer is worn equivalent to fragile epidermis
Soft coat；In addition, a kind of gentle face cream containing a variety of pure natural plant extracts of the present invention meets through examining
National sector standard, its indices comply fully with sanitary quality standard and the security requirement of national regulation.
Certainly, it is the representative instance of the present invention above, in addition, the present invention can also have other a variety of specific implementations
The technical scheme of mode, all use equivalent substitutions or equivalent transformation formation, all falls within the scope of protection of present invention.
Claims (4)
1. a kind of skin cream with steroid dependent dermatitis repair function, it is characterised in that including following percentage by weight
Raw material：Hydrolecithin 1.5%, laruyl alcohol phosphate potassium 0.3%, camellia seed oil 6.0%, evening primrose oil 4.0%, cetearyl alcohol
Alcohol 2.5%, olive oil 2.0%, vitamin E 0.2%, phytosterols oletate 0.5%, dimethyl silicone polymer 1.0%,
Disodium ethylene diamine tetraacetate 0.05%, Natrulon H-10 8.0%, carbomer 0.2%, arginine 0.2%, Sodium Hyaluronate
0.05%th, Wild soybean peptide 0.3-0.5%, bluish-green microalgae extract 1.5-2.5%, yeast product 0.5-1.5%, the light of soybean
Fruit licorice root extract 0.2-0.8%, purslane extract 0.5-1.5%, carbohydrate isomer 3.0-5.0%, centella
Extract 0.3-0.8%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
2. the skin cream according to claim 1 with steroid dependent dermatitis repair function, it is characterised in that：Including with
The raw material of lower percentage by weight：Hydrolecithin 1.5%, laruyl alcohol phosphate potassium 0.3%, camellia seed oil 6.0%, evening primrose oil
4.0%th, cetostearyl alcohol 2.5%, olive oil 2.0%, vitamin E 0.2%, phytosterols oletate 0.5%, poly- two
Methylsiloxane 1.0%, disodium ethylene diamine tetraacetate 0.05%, Natrulon H-10 8.0%, carbomer 0.2%, arginine
0.2%th, Sodium Hyaluronate 0.05%, Wild soybean peptide 0.3%, bluish-green microalgae extract 1.5%, the yeast product of soybean
0.5%th, glycyrrhiza glabra root extract 0.2%, purslane extract 0.5%, carbohydrate isomer 3.0%, centella are extracted
Thing 0.3%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
3. the skin cream according to claim 1 with steroid dependent dermatitis repair function, it is characterised in that：Including with
The raw material of lower percentage by weight：Hydrolecithin 1.5%, laruyl alcohol phosphate potassium 0.3%, camellia seed oil 6.0%, evening primrose oil
4.0%th, cetostearyl alcohol 2.5%, olive oil 2.0%, vitamin E 0.2%, phytosterols oletate 0.5%, poly- two
Methylsiloxane 1.0%, disodium ethylene diamine tetraacetate 0.05%, Natrulon H-10 8.0%, carbomer 0.2%, arginine
0.2%th, Sodium Hyaluronate 0.05%, Wild soybean peptide 0.5%, bluish-green microalgae extract 2.5%, the yeast product of soybean
1.5%th, glycyrrhiza glabra root extract 0.8%, purslane extract 1.5%, carbohydrate isomer 5.0%, centella are extracted
Thing 0.8%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
4. the skin cream according to claim 1 with steroid dependent dermatitis repair function, it is characterised in that：Including with
The raw material of lower percentage by weight：Hydrolecithin 1.5%, laruyl alcohol phosphate potassium 0.3%, camellia seed oil 6.0%, evening primrose oil
4.0%th, cetostearyl alcohol 2.5%, olive oil 2.0%, vitamin E 0.2%, phytosterols oletate 0.5%, poly- two
Methylsiloxane 1.0%, disodium ethylene diamine tetraacetate 0.05%, Natrulon H-10 8.0%, carbomer 0.2%, arginine
0.2%th, Sodium Hyaluronate 0.05%, Wild soybean peptide 0.4%, bluish-green microalgae extract 2.0%, the yeast product of soybean
1.0%th, glycyrrhiza glabra root extract 0.5%, purslane extract 1.0%, carbohydrate isomer 4.0%, centella are extracted
Thing 0.55%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.3%, surplus are water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201710300396.5A CN107184410A (en) | 2017-04-28 | 2017-04-28 | A kind of skin cream with steroid dependent dermatitis repair function |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710300396.5A CN107184410A (en) | 2017-04-28 | 2017-04-28 | A kind of skin cream with steroid dependent dermatitis repair function |
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| CN107184410A true CN107184410A (en) | 2017-09-22 |
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| CN201710300396.5A Pending CN107184410A (en) | 2017-04-28 | 2017-04-28 | A kind of skin cream with steroid dependent dermatitis repair function |
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| CN109568190A (en) * | 2018-12-30 | 2019-04-05 | 广州瑞誉化工科技有限公司 | A kind of skin composition and its preparation method and application for repairing sunburn |
| CN109797133A (en) * | 2019-01-09 | 2019-05-24 | 珠海金肽生物科技有限公司 | Multipotential cell culture composition and preparation method and application |
| CN110478310A (en) * | 2019-09-27 | 2019-11-22 | 无锡宾西利悦科技有限公司 | A kind of composition for the treatment of and Reduce allergy |
| CN110693737A (en) * | 2019-11-04 | 2020-01-17 | 彭氏(惠州)实业发展有限公司 | High-pearly-luster isolating and brightening emulsion and preparation method thereof |
| IT201800007565A1 (en) * | 2018-07-27 | 2020-01-27 | Svas Biosana Spa | FORMULATION FOR THE TOPICAL TREATMENT OF THE SKIN AND RELATIVE USE |
| CN110917067A (en) * | 2019-12-04 | 2020-03-27 | 九牧厨卫股份有限公司 | A skin caring cream with high moisture keeping effect for bath and its preparation method |
| CN112826786A (en) * | 2020-12-31 | 2021-05-25 | 国润生物科技（深圳）有限公司 | Targeted scar repairing mesh construction composition and application thereof |
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Application publication date: 20170922 |