CN103269685A - 氨溴索水溶液 - Google Patents

氨溴索水溶液 Download PDF

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Publication number
CN103269685A
CN103269685A CN2011800583550A CN201180058355A CN103269685A CN 103269685 A CN103269685 A CN 103269685A CN 2011800583550 A CN2011800583550 A CN 2011800583550A CN 201180058355 A CN201180058355 A CN 201180058355A CN 103269685 A CN103269685 A CN 103269685A
Authority
CN
China
Prior art keywords
aqueous solution
ambroxol
polyalcohols
preparation
glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011800583550A
Other languages
English (en)
Chinese (zh)
Inventor
G·帕塞蒂
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LECTIO PHARMAENTWICKLUNGS- und VERWERTUNGS GmbH
Original Assignee
LECTIO PHARMAENTWICKLUNGS- und VERWERTUNGS GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45094329&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN103269685(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LECTIO PHARMAENTWICKLUNGS- und VERWERTUNGS GmbH filed Critical LECTIO PHARMAENTWICKLUNGS- und VERWERTUNGS GmbH
Publication of CN103269685A publication Critical patent/CN103269685A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
CN2011800583550A 2010-12-23 2011-12-22 氨溴索水溶液 Pending CN103269685A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP10196711.5 2010-12-23
EP10196711 2010-12-23
US201061428269P 2010-12-30 2010-12-30
US61/428,269 2010-12-30
PCT/EP2011/073754 WO2012085185A1 (en) 2010-12-23 2011-12-22 Aqueous solution of ambroxol

Publications (1)

Publication Number Publication Date
CN103269685A true CN103269685A (zh) 2013-08-28

Family

ID=45094329

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011800583550A Pending CN103269685A (zh) 2010-12-23 2011-12-22 氨溴索水溶液

Country Status (13)

Country Link
EP (1) EP2654719A1 (pt)
JP (1) JP2014503542A (pt)
KR (1) KR20130140042A (pt)
CN (1) CN103269685A (pt)
AR (1) AR084537A1 (pt)
AU (1) AU2011347257A1 (pt)
BR (1) BR112013012815A2 (pt)
CA (1) CA2817453A1 (pt)
CL (1) CL2013001297A1 (pt)
EA (1) EA201300535A1 (pt)
MX (1) MX2013005500A (pt)
NZ (1) NZ609742A (pt)
WO (1) WO2012085185A1 (pt)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105287367A (zh) * 2015-10-13 2016-02-03 华润三九（南昌）药业有限公司 一种盐酸氨溴索的口服液体制剂及其制备方法与应用
CN109060473A (zh) * 2018-07-27 2018-12-21 商洛学院 一种盐酸氨溴索杂质对照品的制备方法
CN112168782A (zh) * 2020-10-26 2021-01-05 山东裕欣药业有限公司 一种呼吸系统药物口服喷雾剂的制备方法
CN112168783A (zh) * 2020-10-26 2021-01-05 山东裕欣药业有限公司 一种呼吸系统药物口服喷雾剂及制备方法
CN113995721A (zh) * 2020-07-27 2022-02-01 德国吉麦医疗技术有限公司 一种盐酸氨溴索口腔喷雾溶液及其制备方法
CN114129510A (zh) * 2021-12-03 2022-03-04 聊城大学 一种复方磺胺注射剂及制备方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102083621B1 (ko) * 2013-06-13 2020-03-02 한미약품 주식회사 암브록솔 및 레보드로프로피진을 포함하는 안정성이 개선된 경구용 액상 제제
CN103462942B (zh) * 2013-08-20 2016-12-28 湖南赛隆药业有限公司 一种吸入用盐酸氨溴索溶液
CN104316482A (zh) * 2014-08-15 2015-01-28 河北菲尼斯生物技术有限公司 一种盐酸氨溴索颗粒的质量控制方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000007561A (ja) * 1998-06-18 2000-01-11 Nissho Corp 塩酸アンブロキソール水溶液製剤
CN1870912A (zh) * 2003-09-09 2006-11-29 3M创新有限公司 浓缩的抗菌组合物和方法
CN101961307A (zh) * 2010-09-14 2011-02-02 武汉人福药业有限责任公司 治疗呼吸道疾病的口服液及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU574360B2 (en) * 1983-05-13 1988-07-07 Reichert, D. Antisnoring agent
DE19933148A1 (de) 1999-07-20 2001-01-25 Boehringer Ingelheim Int Ambroxolhaltige Lutschtablette
US7138133B2 (en) 2001-10-10 2006-11-21 The Procter & Gamble Company Orally administered liquid compositions
US20030171391A1 (en) 2002-01-25 2003-09-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of chronic pain
DE10240802A1 (de) 2002-08-30 2004-04-15 W.L. Gore & Associates Gmbh IR reflektierendes Material
DE10332486A1 (de) 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung akuter Schmerzen
US20050075403A1 (en) 2003-10-02 2005-04-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of inflammation in the pharynx
ITMI20032463A1 (it) 2003-12-16 2005-06-17 Advance Holdings Ltd Soluzione acquosa concentrata a base di ambroxolo
DE102004021992A1 (de) * 2004-05-03 2005-11-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Topische Zubereitung enthaltend Ambroxol

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000007561A (ja) * 1998-06-18 2000-01-11 Nissho Corp 塩酸アンブロキソール水溶液製剤
CN1870912A (zh) * 2003-09-09 2006-11-29 3M创新有限公司 浓缩的抗菌组合物和方法
CN101961307A (zh) * 2010-09-14 2011-02-02 武汉人福药业有限责任公司 治疗呼吸道疾病的口服液及其制备方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王晨曦: "化妆品防腐剂的分类", 《HTTP://BLOG.SINA.COM.CN/S/BLOG_611E5DF5010011CN.HTML》, 26 August 2010 (2010-08-26) *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105287367A (zh) * 2015-10-13 2016-02-03 华润三九（南昌）药业有限公司 一种盐酸氨溴索的口服液体制剂及其制备方法与应用
CN105287367B (zh) * 2015-10-13 2018-07-10 华润三九（南昌）药业有限公司 一种盐酸氨溴索的口服液体制剂及其制备方法与应用
CN109060473A (zh) * 2018-07-27 2018-12-21 商洛学院 一种盐酸氨溴索杂质对照品的制备方法
CN113995721A (zh) * 2020-07-27 2022-02-01 德国吉麦医疗技术有限公司 一种盐酸氨溴索口腔喷雾溶液及其制备方法
CN112168782A (zh) * 2020-10-26 2021-01-05 山东裕欣药业有限公司 一种呼吸系统药物口服喷雾剂的制备方法
CN112168783A (zh) * 2020-10-26 2021-01-05 山东裕欣药业有限公司 一种呼吸系统药物口服喷雾剂及制备方法
CN114129510A (zh) * 2021-12-03 2022-03-04 聊城大学 一种复方磺胺注射剂及制备方法

Also Published As

Publication number Publication date
JP2014503542A (ja) 2014-02-13
KR20130140042A (ko) 2013-12-23
CL2013001297A1 (es) 2013-10-11
WO2012085185A1 (en) 2012-06-28
CA2817453A1 (en) 2012-06-28
NZ609742A (en) 2015-01-30
MX2013005500A (es) 2013-09-26
BR112013012815A2 (pt) 2016-09-13
AU2011347257A1 (en) 2013-05-23
AR084537A1 (es) 2013-05-22
EP2654719A1 (en) 2013-10-30
EA201300535A1 (ru) 2013-08-30

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WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20130828