CN103249709B - O-取代的羟基羧酸的酯及其制备 - Google Patents

O-取代的羟基羧酸的酯及其制备 Download PDF

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Publication number
CN103249709B
CN103249709B CN201180047315.6A CN201180047315A CN103249709B CN 103249709 B CN103249709 B CN 103249709B CN 201180047315 A CN201180047315 A CN 201180047315A CN 103249709 B CN103249709 B CN 103249709B
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substituted
formula
branched
chain
ester
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Chinese (zh)
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CN103249709A (zh
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邓榴
N.W.波阿斯
S.德莱尔
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Chanel Perfume Co
Eastman Chemical Co
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Chanel Perfume Co
Eastman Chemical Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
    • C07C67/11—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond being mineral ester groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/002—Aftershave preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Catalysts (AREA)
CN201180047315.6A 2010-07-29 2011-07-26 O-取代的羟基羧酸的酯及其制备 Active CN103249709B (zh)

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US36885010P 2010-07-29 2010-07-29
US61/368,850 2010-07-29
US61/368850 2010-07-29
US12/975,572 US8846723B2 (en) 2010-07-29 2010-12-22 Esters of O-substituted hydroxy carboxylic acids and preparations thereof
US12/975572 2010-12-22
US12/975,572 2010-12-22
PCT/US2011/045303 WO2012015790A1 (en) 2010-07-29 2011-07-26 Esters of o-substituted hydroxy carboxylic acids and preparations thereof

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KR (1) KR101899606B1 (enExample)
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Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8613940B2 (en) 2010-09-03 2013-12-24 Eastman Chemical Company Carbonate derivatives as skin care
WO2012041395A1 (en) * 2010-10-01 2012-04-05 Loctite (R & D) Limited Alpha-cyanoacrylate ester synthesis
US8329938B2 (en) 2011-02-21 2012-12-11 Eastman Chemical Company Hydroxyalkanoic acid and hydroxyalkanoice acid oligomer esters of retinol
KR102634263B1 (ko) * 2015-12-01 2024-02-06 (주)아모레퍼시픽 신규 히드록시 피라논 화합물, 이의 제조방법 및 이를 포함하는 화장료 조성물
KR102463238B1 (ko) * 2015-12-01 2022-11-04 (주)아모레퍼시픽 신규 히드록시 피라논 화합물, 이의 제조방법 및 이를 포함하는 화장료 조성물
US10535506B2 (en) * 2016-01-13 2020-01-14 Mks Instruments, Inc. Method and apparatus for deposition cleaning in a pumping line
US11020334B2 (en) * 2017-02-17 2021-06-01 Illustris Pharmaceuticals, Inc. Compounds, compositions and use thereof
WO2019236772A1 (en) 2018-06-05 2019-12-12 Flagship Pioneering Innovations V, Inc. Acylated active agents and methods of their use for the treatment of autoimmune disorders
EP3981397A1 (en) * 2020-10-08 2022-04-13 Global Scientific Tocotrienols derivates, methods and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997020812A1 (en) * 1995-12-04 1997-06-12 Advanced Polymer Systems, Inc. RETINYL ESTERS OF α-HYDROXY ACIDS FOR TOPICAL IMPROVEMENT OF SKIN FUNCTION AND APPEARANCE
CN1455780A (zh) * 2001-01-11 2003-11-12 株式会社开备传 新视黄醇衍生物、其制备方法和用途
CN1620446A (zh) * 2002-12-18 2005-05-25 高丽雅娜化妆品股份有限公司 新型视黄醇衍生物及包含该视黄醇衍生物的化妆品组合物
CN101772482A (zh) * 2007-08-08 2010-07-07 伊士曼化工公司 长链醇的酯及其制备

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH230446A (de) 1938-07-02 1943-12-31 Chem Ind Basel Verfahren zur Darstellung eines neuen Esters der Oxy-stilbenreihe.
US2302618A (en) * 1939-08-05 1942-11-17 Du Pont Preparation of organic esters
US2518456A (en) * 1946-04-19 1950-08-15 Martin L Fein Preparation of acyloxy carboxylic acids from esters of hydroxy carboxylic acids
US3682968A (en) 1969-06-25 1972-08-08 Merck & Co Inc Anti-inflammatory salicylic acid derivatives
GB1426869A (en) 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
US3980793A (en) 1972-03-13 1976-09-14 Astra Lakemedel Aktiebolag Carbonate esters of penicillins and compositions and methods for treatment of bacterial infections
US4107290A (en) 1972-06-29 1978-08-15 L'oreal Anti-solar polymers, method of making the same and cosmetic compositions containing the same
US4216224A (en) 1978-09-22 1980-08-05 Scott Eugene J Van Methods and compositions for treating psoriasis with retinoyl compounds
JPS61126069A (ja) * 1984-11-21 1986-06-13 Res Dev Corp Of Japan プロスタグランジン誘導体
ZW7487A1 (en) 1986-05-23 1987-12-16 Hoffmann La Roche Tetrahydronaphthaline and indane derivatives
US5750568A (en) 1986-06-11 1998-05-12 Procyon Pharmaceuticals, Inc. Protein kinase C Modulators. L.
GB8811410D0 (en) 1988-05-13 1988-06-15 Unilever Plc Treatment of skin disorders
CA2178964A1 (en) 1993-12-15 1995-06-22 John A. Duffy Novel retinoid conjugate compounds and methods for treating skin aging
DE4415204A1 (de) 1994-04-30 1995-11-02 Carl Heinrich Dr Weischer Neue Retinol (Vitamin A) -Derivate, deren Herstellung und Verwendung als Arzneimittel und Kosmetika
JPH08337523A (ja) 1995-06-14 1996-12-24 Taiho Yakuhin Kogyo Kk 血管新生阻害剤
US6306818B1 (en) 1996-06-24 2001-10-23 Givaudan Roure (International) Sa Fragrance precursors
DE19631685A1 (de) 1996-08-06 1998-02-12 Wella Ag Hydrolytisch spaltbare Wirkstoffderivate, diese enthaltene Haarbehandlungsmittel und Verfahren zum Behandeln von Haaren
TW432055B (en) * 1997-05-16 2001-05-01 Ciba Sc Holding Ag Resorcinyl-triazines, their preparation process and a cosmetic composition containing them
FR2766176B1 (fr) 1997-07-15 1999-10-29 Caudalie Compositions a base de derives de resveratrol
DE19750526A1 (de) 1997-11-14 1999-05-20 Basf Ag Ascorbinsäurederivate enthaltende kosmetische und pharmazeutische Zubereitungen
DE69909073T2 (de) 1998-02-12 2004-05-19 De Montfort University Durch hydroxylierung aktivierte wirkstofffreigabe
DE19949284A1 (de) 1999-10-12 2001-04-19 Basf Ag Chirale Verbindung und deren Verwendung als chirale Dotierstoffe zur Herstellung von cholesterisch-flüssigkristallinen Zusammensetzungen
DE10016524A1 (de) 2000-04-03 2001-10-04 Basf Ag Polymerisierbare Flüssigkristalle
JP2001294558A (ja) * 2000-04-12 2001-10-23 Honshu Chem Ind Co Ltd ノルボルネンー２−カルボン酸エステル類及びその製造方法
JP2002193752A (ja) 2000-12-25 2002-07-10 Kanebo Ltd 毛髪処理剤
US7091186B2 (en) 2001-09-24 2006-08-15 Seattle Genetics, Inc. p-Amidobenzylethers in drug delivery agents
WO2003037933A2 (de) 2001-10-30 2003-05-08 Pentapharm Ag Dermopharmazeutisch und kosmetisch wirksame oligopeptide
DE10201223A1 (de) * 2002-01-15 2003-07-24 Knut Oppenlaender Neuartige Antioxidantien für Pharma und Kosmetik auf Basis von Phenolen, Polyphenolen und natürlichen Vitaminen und Verfahren zu ihrer Herstellung
ES2411656T3 (es) 2002-03-13 2013-07-08 Thomas SKÖLD Sistemas de administración a base de agua
ES2193874B1 (es) 2002-04-03 2005-03-01 Puleva Biotech, S.A. Compuestos naturales y derivados de estos para la prevencion y el tratamiento de enfermedades cardiovasculares, hepaticas, renales y cosmeticas.
CN1652743A (zh) 2002-04-17 2005-08-10 大正制药株式会社 毛发生长补剂
ES2246603B1 (es) 2002-07-03 2007-06-16 Consejo Sup. De Investig. Cientificas Procedimiento para la preparacion de esteres de hidroxitirosol, esteres obtenidos y utilizacion.
US7985422B2 (en) 2002-08-05 2011-07-26 Torrent Pharmaceuticals Limited Dosage form
GB0306908D0 (en) 2003-03-26 2003-04-30 Angiogene Pharm Ltd Bioreductively activated stilbene prodrugs
US20040248762A1 (en) 2003-06-09 2004-12-09 Mcgee Thomas Malodor counteractant compositions
JP2005041871A (ja) 2003-07-10 2005-02-17 Taisho Pharmaceut Co Ltd ４置換ベンゼン化合物
US7357783B2 (en) 2003-07-17 2008-04-15 Medpro Safety Products, Inc. Safety system for a blood collection device
GB0319401D0 (en) 2003-08-19 2003-09-17 Univ Hull Materials
DK1506781T3 (da) 2003-11-03 2005-06-13 Peter-Hansen Volkmann Vaginalplejesammensætning
ES2233208B1 (es) 2003-11-27 2006-10-01 Puleva Biotech, S.A. Metodo para la preparacion enzimatica de compuestos antioxidantes.
GB0403115D0 (en) 2004-02-12 2004-03-17 Givauden Sa Organic compounds
GB0410134D0 (en) 2004-05-07 2004-06-09 Givaudan Sa Organic compounds
US7772352B2 (en) * 2005-01-28 2010-08-10 Bezwada Biomedical Llc Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices
EP1951260A4 (en) 2005-10-21 2009-11-11 Bezwada Biomedical Llc FUNCTIONALIZED PHENOLIC COMPOUNDS AND POURABLE ARTICLES THEREOF
AU2006313701B2 (en) 2005-11-11 2012-05-31 Aeterna Zentaris Gmbh Novel pyridopyrazines and their use as modulators of kinases
WO2007072503A2 (en) 2005-12-21 2007-06-28 Panacea Biotec Ltd. Combinations for managing inflammation and associated disorders
US7566795B2 (en) * 2006-10-06 2009-07-28 Eastman Chemical Company Preparation of retinyl esters
US20100041633A1 (en) 2007-02-05 2010-02-18 Nicox S.A. Nitric oxide releasing steroids
KR100829890B1 (ko) * 2007-02-08 2008-05-16 주식회사 바이오폴리메드 신규한 레티놀 유도체, 이의 제조방법 및 이를 포함하는주름 개선용 화장료 조성물
DE102007023869A1 (de) 2007-05-21 2008-12-18 Momentive Performance Materials Gmbh & Co. Kg Neue Polycarbonat- und/oder Polyurethan-Polyorganosiloxan-Verbindungen
ES2534900T3 (es) 2007-07-30 2015-04-30 Zynerba Pharmaceuticals, Inc. Profármacos de cannabidiol, composiciones que comprenden los profármacos de cannabidiol y métodos de uso de los mismos
US20090035240A1 (en) 2007-07-31 2009-02-05 Maes Daniel H Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent
US8080583B2 (en) 2007-07-31 2011-12-20 Elc Management Llc Emulsion cosmetic compositions containing resveratrol derivatives and linear or branched silicone
US8344024B2 (en) 2007-07-31 2013-01-01 Elc Management Llc Anhydrous cosmetic compositions containing resveratrol derivatives
US9295621B2 (en) 2007-07-31 2016-03-29 Elc Management Llc Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant
US20090035236A1 (en) 2007-07-31 2009-02-05 Maes Daniel H Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent
FR2919800B1 (fr) 2007-08-06 2010-08-27 Biochimie Appliquee Solabia So Compositions cosmetiques et/ou dermatologiques contenant un ester de tyrosol ou d'hydroxytyrosol et d'acide gras insature, et leurs utilisations
JP5281645B2 (ja) 2007-09-08 2013-09-04 イーエルシー マネージメント エルエルシー フェルラ酸レスベラトロール化合物、それらの化合物を含有する組成物およびそれらの使用方法。
JP2009079021A (ja) 2007-09-27 2009-04-16 Eiweiss Kk 新規化合物、光電子供与化合物およびこれらを含む光酸発生剤
DE602007010967D1 (de) 2007-12-21 2011-01-13 Kosmetische und pharmazeutische Zusammensetzungen
MX337656B (es) 2008-02-11 2016-03-14 Univ Washington Metodos para el tratamiento y prevencion de disfuncion retinal relacionada con la edad.
KR20100126734A (ko) * 2008-03-12 2010-12-02 다이셀 가가꾸 고교 가부시끼가이샤 락톤 골격을 포함하는 단량체, 고분자 화합물 및 포토레지스트 조성물
JP5597925B2 (ja) 2008-03-12 2014-10-01 Ｊｎｃ株式会社 重合性液晶組成物およびその用途
BRPI0914926B1 (pt) 2008-06-25 2022-04-12 Basf Se Uso de benzotropolona e derivados da mesma
WO2010015529A1 (en) 2008-08-05 2010-02-11 Nicox S.A. New no releasing steroids derivatives
KR101039750B1 (ko) 2008-12-01 2011-06-09 한국생명공학연구원 신규 쿠마린계 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 다약제내성 억제용 약학적 조성물
JP5398272B2 (ja) * 2009-01-09 2014-01-29 東京応化工業株式会社 レジスト組成物およびレジストパターン形成方法
US8513374B2 (en) 2009-09-30 2013-08-20 Falguni Dasgupta Biocompatible and biodegradable polymers from renewable natural polyphenols
JP5738400B2 (ja) 2010-04-21 2015-06-24 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ バニラ臭を有する有機カルボナート

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997020812A1 (en) * 1995-12-04 1997-06-12 Advanced Polymer Systems, Inc. RETINYL ESTERS OF α-HYDROXY ACIDS FOR TOPICAL IMPROVEMENT OF SKIN FUNCTION AND APPEARANCE
CN1455780A (zh) * 2001-01-11 2003-11-12 株式会社开备传 新视黄醇衍生物、其制备方法和用途
CN1620446A (zh) * 2002-12-18 2005-05-25 高丽雅娜化妆品股份有限公司 新型视黄醇衍生物及包含该视黄醇衍生物的化妆品组合物
CN101772482A (zh) * 2007-08-08 2010-07-07 伊士曼化工公司 长链醇的酯及其制备

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JP2013539457A (ja) 2013-10-24
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