MX337656B - Metodos para el tratamiento y prevencion de disfuncion retinal relacionada con la edad. - Google Patents

Metodos para el tratamiento y prevencion de disfuncion retinal relacionada con la edad.

Info

Publication number
MX337656B
MX337656B MX2010008847A MX2010008847A MX337656B MX 337656 B MX337656 B MX 337656B MX 2010008847 A MX2010008847 A MX 2010008847A MX 2010008847 A MX2010008847 A MX 2010008847A MX 337656 B MX337656 B MX 337656B
Authority
MX
Mexico
Prior art keywords
age
prevention
treatment
methods
retinal dysfunction
Prior art date
Application number
MX2010008847A
Other languages
English (en)
Other versions
MX2010008847A (es
Inventor
Krzysztof Palczewski
Tadao Maeda
David Saperstein
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of MX2010008847A publication Critical patent/MX2010008847A/es
Publication of MX337656B publication Critical patent/MX337656B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un método de tratamiento o prevención de disfunción retinal relacionada con la edad involucra la administración a un paciente de una cantidad farmacéuticamente efectiva de un derivado de retinal sintético, repetidamente en una duración de por lo menos aproximadamente tres meses. Los derivados de retinal sintéticos efectivos incluyen ésteres de 9-cis-retinilo, ésteres de 11-cis-retinilo, derivados y congéneres de los mismos, y combinaciones de los mismos. Los sustituyentes adecuados de éster incluyen carboxilatos de ácidos monocarboxilicos de C1 a C10 y ácidos policarboxílicos de C2 a C22.
MX2010008847A 2008-02-11 2009-02-10 Metodos para el tratamiento y prevencion de disfuncion retinal relacionada con la edad. MX337656B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2762508P 2008-02-11 2008-02-11
PCT/US2009/000824 WO2009102418A1 (en) 2008-02-11 2009-02-10 Methods for the treatment and prevention of age-related retinal dysfunction

Publications (2)

Publication Number Publication Date
MX2010008847A MX2010008847A (es) 2010-11-30
MX337656B true MX337656B (es) 2016-03-14

Family

ID=40521846

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010008847A MX337656B (es) 2008-02-11 2009-02-10 Metodos para el tratamiento y prevencion de disfuncion retinal relacionada con la edad.

Country Status (14)

Country Link
US (7) US8324270B2 (es)
EP (1) EP2252276B1 (es)
JP (3) JP6022746B2 (es)
KR (2) KR20160092032A (es)
CN (1) CN101969938A (es)
AU (1) AU2009213138B2 (es)
BR (1) BRPI0908154A2 (es)
CA (2) CA3018374A1 (es)
IL (2) IL207220B (es)
MX (1) MX337656B (es)
NZ (3) NZ600498A (es)
RU (1) RU2565448C2 (es)
WO (1) WO2009102418A1 (es)
ZA (1) ZA201005434B (es)

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US10414732B2 (en) 2017-03-16 2019-09-17 Aldeyra Therapeutics, Inc. Polymorphic compounds and uses thereof
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CA3178762A1 (en) * 2020-06-09 2021-12-16 Eluminex Biosciences (Suzhou) Limited Methods of treating visual disorders using daily low dosing of a retinoid compound

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Also Published As

Publication number Publication date
JP2016190852A (ja) 2016-11-10
JP2014221828A (ja) 2014-11-27
JP6272943B2 (ja) 2018-01-31
RU2565448C2 (ru) 2015-10-20
US8324270B2 (en) 2012-12-04
US20100035986A1 (en) 2010-02-11
KR20160092032A (ko) 2016-08-03
EP2252276B1 (en) 2019-03-27
US20160331713A1 (en) 2016-11-17
KR101810381B1 (ko) 2017-12-19
BRPI0908154A2 (pt) 2015-08-11
IL207220B (en) 2018-04-30
NZ617701A (en) 2015-06-26
CA2714530C (en) 2018-09-25
EP2252276A1 (en) 2010-11-24
CA2714530A1 (en) 2009-08-20
ZA201005434B (en) 2011-11-30
RU2010137842A (ru) 2012-03-20
AU2009213138B2 (en) 2014-11-06
US20130072561A1 (en) 2013-03-21
AU2009213138A1 (en) 2009-08-20
US20190133986A1 (en) 2019-05-09
US9408821B2 (en) 2016-08-09
CN101969938A (zh) 2011-02-09
MX2010008847A (es) 2010-11-30
US9855239B2 (en) 2018-01-02
JP6022746B2 (ja) 2016-11-09
NZ587376A (en) 2012-06-29
US9233091B2 (en) 2016-01-12
JP2011511789A (ja) 2011-04-14
IL258356A (en) 2018-05-31
WO2009102418A1 (en) 2009-08-20
KR20100126358A (ko) 2010-12-01
IL207220A0 (en) 2010-12-30
JP5934304B2 (ja) 2016-06-15
CA3018374A1 (en) 2009-08-20
US20180098955A1 (en) 2018-04-12
NZ600498A (en) 2014-01-31
US20130072557A1 (en) 2013-03-21
US20130072558A1 (en) 2013-03-21

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