CN103180324A - 腔肠素衍生物及其使用方法 - Google Patents

腔肠素衍生物及其使用方法 Download PDF

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Publication number
CN103180324A
CN103180324A CN201180052806XA CN201180052806A CN103180324A CN 103180324 A CN103180324 A CN 103180324A CN 201180052806X A CN201180052806X A CN 201180052806XA CN 201180052806 A CN201180052806 A CN 201180052806A CN 103180324 A CN103180324 A CN 103180324A
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alkyl
substituted
heteroaryl
aryl
group
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Chinese (zh)
Inventor
D.H.克劳伯特
P.梅森黑默
J.安奇
W.周
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Promega Corp
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Promega Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN201180052806XA 2010-11-02 2011-11-02 腔肠素衍生物及其使用方法 Pending CN103180324A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40941310P 2010-11-02 2010-11-02
US61/409413 2010-11-02
PCT/US2011/058924 WO2012061477A1 (en) 2010-11-02 2011-11-02 Coelenterazine derivatives and methods of using same

Publications (1)

Publication Number Publication Date
CN103180324A true CN103180324A (zh) 2013-06-26

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CN201180052806XA Pending CN103180324A (zh) 2010-11-02 2011-11-02 腔肠素衍生物及其使用方法

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US (1) US9487520B2 (https=)
EP (1) EP2635583B1 (https=)
JP (1) JP6040157B2 (https=)
KR (1) KR101968475B1 (https=)
CN (1) CN103180324A (https=)
AU (1) AU2011323455B2 (https=)
BR (1) BR112013010484B1 (https=)
CA (1) CA2815381C (https=)
DK (1) DK2635583T3 (https=)
ES (1) ES2543913T3 (https=)
IL (1) IL225869A (https=)
PL (1) PL2635583T3 (https=)
PT (1) PT2635583E (https=)
SG (1) SG189494A1 (https=)
WO (1) WO2012061477A1 (https=)

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* Cited by examiner, † Cited by third party
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CN103180324A (zh) 2010-11-02 2013-06-26 普罗美加公司 腔肠素衍生物及其使用方法
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WO2018049241A1 (en) * 2016-09-09 2018-03-15 Promega Corporation Dual protected pro-coelenterazine substrates
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EP3802514B1 (en) 2018-06-01 2022-08-03 Promega Corporation Inhibitors of oplophorus luciferase-derived bioluminescent complexes
KR102114088B1 (ko) * 2018-09-10 2020-06-17 (주)신우에이엔티 웨이퍼 세정용 나노 버블 분사 구조
CA3114424A1 (en) 2018-10-03 2020-04-09 Promega Corporation Compositions and methods for stabilizing coelenterazine and analogs and derivatives thereof
CA3158729A1 (en) 2019-11-27 2021-06-03 Virginia Kincaid Multipartite luciferase peptides and polypeptides
JP7745550B2 (ja) 2019-12-10 2025-09-29 プロメガ コーポレイション 多官能性プローブを使用する生物発光検出用組成物及び生物発光検出方法
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DK2635583T3 (en) 2015-08-03
CA2815381A1 (en) 2012-05-10
EP2635583B1 (en) 2015-06-03
IL225869A (en) 2017-09-28
PT2635583E (pt) 2015-09-11
AU2011323455B2 (en) 2017-07-27
KR101968475B1 (ko) 2019-04-15
BR112013010484B1 (pt) 2019-09-03
WO2012061477A1 (en) 2012-05-10
ES2543913T3 (es) 2015-08-25
IL225869A0 (en) 2013-07-31
EP2635583A1 (en) 2013-09-11
PL2635583T3 (pl) 2015-11-30
US20120107849A1 (en) 2012-05-03
BR112013010484A2 (pt) 2016-07-05
US9487520B2 (en) 2016-11-08
SG189494A1 (en) 2013-05-31
AU2011323455A1 (en) 2013-05-30
JP6040157B2 (ja) 2016-12-07
CA2815381C (en) 2019-03-19
KR20140003430A (ko) 2014-01-09
JP2013544242A (ja) 2013-12-12

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