CN103120799A - 用于反差成像的充气微泡组合物 - Google Patents

用于反差成像的充气微泡组合物 Download PDF

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Publication number
CN103120799A
CN103120799A CN201310032548XA CN201310032548A CN103120799A CN 103120799 A CN103120799 A CN 103120799A CN 201310032548X A CN201310032548X A CN 201310032548XA CN 201310032548 A CN201310032548 A CN 201310032548A CN 103120799 A CN103120799 A CN 103120799A
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CN
China
Prior art keywords
gas
microbubbles
composition
microvesicles
acid
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Pending
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CN201310032548XA
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English (en)
Chinese (zh)
Inventor
P·比萨
P·弗兰金
C·吉约
M·施奈德
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Bracco Suisse SA
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Bracco Suisse SA
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Application filed by Bracco Suisse SA filed Critical Bracco Suisse SA
Publication of CN103120799A publication Critical patent/CN103120799A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
CN201310032548XA 2004-08-18 2005-08-17 用于反差成像的充气微泡组合物 Pending CN103120799A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04019557.0 2004-08-18
EP04019557 2004-08-18

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800280529A Division CN101005858A (zh) 2004-08-18 2005-08-17 用于反差成像的充气微泡组合物

Publications (1)

Publication Number Publication Date
CN103120799A true CN103120799A (zh) 2013-05-29

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Family Applications (2)

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CN201310032548XA Pending CN103120799A (zh) 2004-08-18 2005-08-17 用于反差成像的充气微泡组合物
CNA2005800280529A Pending CN101005858A (zh) 2004-08-18 2005-08-17 用于反差成像的充气微泡组合物

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CNA2005800280529A Pending CN101005858A (zh) 2004-08-18 2005-08-17 用于反差成像的充气微泡组合物

Country Status (7)

Country Link
US (2) US9248204B2 (OSRAM)
EP (1) EP1784228B1 (OSRAM)
JP (1) JP4837663B2 (OSRAM)
CN (2) CN103120799A (OSRAM)
AU (1) AU2005273865B2 (OSRAM)
CA (1) CA2575677C (OSRAM)
WO (1) WO2006018433A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111132732A (zh) * 2017-06-29 2020-05-08 医视特有限公司 微泡增强超声治疗中的超声频率和微泡尺寸的优化

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WO2007054561A1 (en) * 2005-11-10 2007-05-18 Bracco Research Sa Instantaneous visualization of contrast agent concentration in imaging applications
EP1951124B1 (en) 2005-11-10 2017-01-04 Bracco Suisse SA Detection of immobilized contrast agent in medical imaging applications based on flow dynamics analysis
JP5313915B2 (ja) 2006-12-21 2013-10-09 ブラッコ・シュイス・ソシエテ・アノニム 医用画像用途における固定化された造影剤の脱離の検知
US9072492B2 (en) 2007-12-28 2015-07-07 Bracco Suisse Sa Quantification analysis of immobilized contrast agent in medical imaging applications
US10130342B2 (en) 2007-12-28 2018-11-20 Bracco Suisse Sa Initialization of fitting parameters for perfusion assessment based on bolus administration
JP2010005512A (ja) * 2008-06-25 2010-01-14 Kao Corp 微細気泡前駆体組成物
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US20130101521A1 (en) * 2010-05-01 2013-04-25 The Trustees Of Columbia University In The City Of New York Methods devices and systems of preparing targeted microbubble shells
WO2011149985A1 (en) * 2010-05-24 2011-12-01 Nanovalent Pharmaceuticals, Inc. Polymerized shell lipid microbubbles and uses thereof
JP6333287B2 (ja) 2012-12-21 2018-05-30 ブラッコ・シュイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ 時間に対する統計的分析に基づく画像診断応用におけるセグメンテーション
US10368842B2 (en) 2014-04-07 2019-08-06 Bracco Suisse S.A. Estimation of acoustic level in-situ with non-fundamental analysis
CN108289654B (zh) 2015-12-10 2021-03-30 博莱科瑞士股份有限公司 通过动态阈值化来检测固定化造影剂
US11035740B1 (en) * 2017-07-31 2021-06-15 Prasidiux, Llc Stimulus indicating device employing thermoreversible amphiphilic gels
WO2019170606A1 (en) * 2018-03-07 2019-09-12 Bracco Suisse Sa Preparation of size-controlled microvesicles
JP7539380B2 (ja) * 2018-12-21 2024-08-23 ブラッコ・スイス・ソシエテ・アノニム リガンドを含むガス充填微小胞
US11246945B2 (en) 2019-06-07 2022-02-15 National Defense Medical Center Cisplatin-loaded microbubbles, pharmaceutical composition for treatment of cancer, method for preparing pharmaceutical compositions and method for treating cancer
CN116917029A (zh) * 2021-03-01 2023-10-20 国立大学法人东京大学 微颗粒和微颗粒分散液
NL2033467B1 (en) 2022-11-04 2024-05-24 Demcon Curonix B V System for generating microvesicles having a predefined size and/or size distribution
NL2037565B1 (en) 2024-04-26 2025-11-11 Demcon Curonix B V Fluid delivery system for providing a flow of microvesicle containing liquid to a subject
CN121107681A (zh) * 2025-11-07 2025-12-12 陕西新天地固体废物综合处置有限公司 一种污泥脱水处理用高效复合絮凝剂及其制备方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111132732A (zh) * 2017-06-29 2020-05-08 医视特有限公司 微泡增强超声治疗中的超声频率和微泡尺寸的优化
CN111132732B (zh) * 2017-06-29 2021-09-21 医视特有限公司 增强对靶组织的治疗同时限制对非靶组织的损伤的系统

Also Published As

Publication number Publication date
CN101005858A (zh) 2007-07-25
US20080008657A1 (en) 2008-01-10
WO2006018433A1 (en) 2006-02-23
EP1784228A1 (en) 2007-05-16
AU2005273865B2 (en) 2011-02-24
CA2575677C (en) 2013-01-22
AU2005273865A1 (en) 2006-02-23
US20160184464A1 (en) 2016-06-30
US10076580B2 (en) 2018-09-18
JP2008509970A (ja) 2008-04-03
US9248204B2 (en) 2016-02-02
CA2575677A1 (en) 2006-02-23
EP1784228B1 (en) 2016-10-05
JP4837663B2 (ja) 2011-12-14

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Application publication date: 20130529