CN102946913B - 具有降低反光的高折射率丙烯酸眼用器件材料 - Google Patents

具有降低反光的高折射率丙烯酸眼用器件材料 Download PDF

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Publication number
CN102946913B
CN102946913B CN201180030684.4A CN201180030684A CN102946913B CN 102946913 B CN102946913 B CN 102946913B CN 201180030684 A CN201180030684 A CN 201180030684A CN 102946913 B CN102946913 B CN 102946913B
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China
Prior art keywords
acrylate
methacrylate
device material
ophthalmic
ent device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201180030684.4A
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English (en)
Chinese (zh)
Other versions
CN102946913A (zh
Inventor
W·R·拉雷多
C·费瑞曼
T·A·卡拉甘
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Alcon Inc
Original Assignee
Novartis AG
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Publication of CN102946913A publication Critical patent/CN102946913A/zh
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Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1602—Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Eyeglasses (AREA)
  • Prostheses (AREA)
CN201180030684.4A 2010-06-21 2011-06-20 具有降低反光的高折射率丙烯酸眼用器件材料 Expired - Fee Related CN102946913B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35696310P 2010-06-21 2010-06-21
US61/356,963 2010-06-21
PCT/US2011/041070 WO2011163126A1 (en) 2010-06-21 2011-06-20 High refractive index, acrylic ophthalmic device materials with reduced glistenings

Publications (2)

Publication Number Publication Date
CN102946913A CN102946913A (zh) 2013-02-27
CN102946913B true CN102946913B (zh) 2015-01-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180030684.4A Expired - Fee Related CN102946913B (zh) 2010-06-21 2011-06-20 具有降低反光的高折射率丙烯酸眼用器件材料

Country Status (19)

Country Link
US (1) US8449610B2 (https=)
EP (1) EP2582409B1 (https=)
JP (1) JP5363683B2 (https=)
KR (1) KR101353975B1 (https=)
CN (1) CN102946913B (https=)
AR (1) AR081963A1 (https=)
AU (1) AU2011271228B2 (https=)
BR (1) BR112012032626A2 (https=)
CA (1) CA2801076C (https=)
ES (1) ES2523387T3 (https=)
IL (1) IL223487A (https=)
MX (1) MX2012015178A (https=)
NZ (1) NZ603881A (https=)
PH (1) PH12012502514A1 (https=)
RU (1) RU2571091C2 (https=)
SG (1) SG186289A1 (https=)
TW (1) TWI473823B (https=)
WO (1) WO2011163126A1 (https=)
ZA (1) ZA201209331B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI517861B (zh) 2011-02-08 2016-01-21 諾華公司 低黏度疏水性眼科裝置材料
TWI513768B (zh) 2011-06-01 2015-12-21 Novartis Ag 疏水性丙烯酸系眼內水晶體材料
TWI551646B (zh) 2011-06-03 2016-10-01 諾華公司 疏水性丙烯酸系眼內水晶體材料
CN103183822B (zh) * 2011-12-28 2016-03-30 辽宁奥克化学股份有限公司 一种不饱和氨酯聚氧烷基醚及其制备方法
AU2012369994B2 (en) * 2012-02-15 2014-12-04 Alcon Inc. Ophthalmic and otorhinolaryngological device materials containing a multi-arm PEG macromer
GB201314455D0 (en) * 2013-08-13 2013-09-25 Contamac Ltd Monomers for use in a polymerizable composition and high refractive index polymer for opthalmic applications
JP6166479B2 (ja) 2013-12-04 2017-07-19 ノバルティス アーゲー 高い屈折率および最小限のグリスニングを有する軟質アクリル材料
US10351637B2 (en) 2014-05-07 2019-07-16 Tubitak Formulation and lens manufacturing process for the production of intraocular lens (IOL)
CN106999628A (zh) * 2014-12-16 2017-08-01 诺华股份有限公司 用于眼科装置的疏水性丙烯酸酯‑丙烯酰胺共聚物
EP3200840B1 (en) 2014-12-16 2021-11-17 Alcon Inc. Low-water content acrylate-acrylamide copolymers for ophthalmic devices
JP6397136B2 (ja) 2015-02-16 2018-09-26 ノバルティス アーゲー 高屈折率を有するウエットパック眼内レンズ材料
CN105536053B (zh) * 2015-12-29 2018-10-02 哈尔滨工业大学 一种作为人工晶状体材料的亲水性形状记忆水凝胶
US20190185629A1 (en) * 2016-08-05 2019-06-20 Microoptx Inc. Polymeric devices and methods of making
EP3363794A1 (en) * 2017-02-15 2018-08-22 Merck Patent GmbH Bis-compounds for optically active devices
AU2018279271B2 (en) * 2017-06-05 2022-11-10 Alcon Inc. High refractive index, high Abbe number intraocular lens materials
TW201927263A (zh) 2017-12-18 2019-07-16 瑞士商諾華公司 觸覺力分佈得到改善的眼內透鏡平台
US11478630B2 (en) * 2017-12-18 2022-10-25 Dan Sachs Devices, systems and methods for therapeutic muscle stimulation
TW201927262A (zh) 2017-12-20 2019-07-16 瑞士商諾華公司 具有前偏置光學設計之眼內透鏡
EP3745999B1 (en) * 2018-01-31 2026-04-29 Menicon Co., Ltd. Intraocular lens
EP3934705B1 (en) * 2019-03-07 2025-11-19 Teleon Holding B.V. Intraocular lens compositions
US11708440B2 (en) 2019-05-03 2023-07-25 Johnson & Johnson Surgical Vision, Inc. High refractive index, high Abbe compositions
KR102894609B1 (ko) 2019-05-03 2025-12-04 존슨 앤드 존슨 서지컬 비전, 인코포레이티드 고 굴절률, 고 아베 조성물
US11795252B2 (en) 2020-10-29 2023-10-24 Johnson & Johnson Surgical Vision, Inc. Compositions with high refractive index and Abbe number
CN113527567B (zh) * 2021-07-26 2023-01-24 康小林 疏水性无闪光点高折光率眼科聚合物材料

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693095A (en) * 1995-06-07 1997-12-02 Alcon Laboratories, Inc. High refractive index ophthalmic lens materials
CN1290352A (zh) * 1998-04-15 2001-04-04 阿尔康实验室公司 高折射率眼科装置用材料
JP2005160565A (ja) * 2003-11-28 2005-06-23 Nidek Co Ltd 眼内レンズ
CN1995077A (zh) * 2006-01-05 2007-07-11 苏州六六明人工晶体有限公司 疏水性透明丙烯酸酯共聚物及其应用
CN101137684A (zh) * 2005-03-09 2008-03-05 Hoya株式会社 (甲基)丙烯酸酯化合物及其制备方法、(甲基)丙烯酸酯共聚物及其制备方法以及软性眼内透镜
US20090093592A1 (en) * 2007-10-05 2009-04-09 Alcon, Inc. Ophthalmic and otorhinolaryngological device materials
CN101495887A (zh) * 2006-07-28 2009-07-29 先进视觉科学有限公司 眼科用水塑化高折射率聚合物
CN101563115A (zh) * 2006-07-21 2009-10-21 爱尔康公司 低粘着性的眼用和耳鼻喉用器件材料
CN101617248A (zh) * 2007-02-23 2009-12-30 埃西勒国际通用光学公司 制造涂覆有具有改进的粘附性和耐磨性的抗反射涂层或反光涂层的光学制品的方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304895A (en) 1973-06-20 1981-12-08 Wesley-Jessen, Inc. Ultraviolet absorbing corneal contact lenses
US4528311A (en) 1983-07-11 1985-07-09 Iolab Corporation Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxyphenyl-2H-benzotriazoles
US5290892A (en) 1990-11-07 1994-03-01 Nestle S.A. Flexible intraocular lenses made from high refractive index polymers
US5331073A (en) 1992-11-09 1994-07-19 Allergan, Inc. Polymeric compositions and intraocular lenses made from same
US5470932A (en) 1993-10-18 1995-11-28 Alcon Laboratories, Inc. Polymerizable yellow dyes and their use in opthalmic lenses
US6353069B1 (en) 1998-04-15 2002-03-05 Alcon Manufacturing, Ltd. High refractive index ophthalmic device materials
US6281319B1 (en) * 1999-04-12 2001-08-28 Surgidev Corporation Water plasticized high refractive index polymer for ophthalmic applications
JP4607406B2 (ja) * 1999-09-03 2011-01-05 フェンウォール、インコーポレイテッド プログラム可能な、流体圧作動血液処理システムおよび方法
US6528602B1 (en) 1999-09-07 2003-03-04 Alcon Universal Ltd. Foldable ophthalmic and otorhinolaryngological device materials
FR2808201B1 (fr) 2000-04-26 2002-07-26 Ass Pour Les Transferts De Tec Lentille souple intraoculaire a caracteristiques d'hydrophilicite ameliorees et son procede d'obtention
US8153156B2 (en) 2002-11-13 2012-04-10 The United States Of America As Represented By The Department Of Veteran Affairs Hydrogel nanocompsites for ophthalmic applications
US7157538B2 (en) * 2004-08-13 2007-01-02 Alcon, Inc. Covalently-bound, hydrophilic coating compositions for surgical implants
US7789509B2 (en) 2006-06-01 2010-09-07 Advanced Vision Science, Inc. Non- or reduced glistenings intraocular lens and method of manufacturing same
WO2007149083A1 (en) 2006-06-21 2007-12-27 Bausch & Lomb Incorporated Polymerizable surfactants and their use as device forming comonomers
US7714039B2 (en) 2006-07-21 2010-05-11 Alcon, Inc. Low-tack ophthalmic and otorhinolaryngological device materials
ES2365290T3 (es) 2007-07-25 2011-09-28 Alcon, Inc. Materiales para dispositivo oftálmico de alto índice de refracción.
TW200920330A (en) 2007-10-02 2009-05-16 Alcon Inc Ophthalmic and otorhinolaryngological device materials containing an alkyl ethoxylate
TW200916130A (en) 2007-10-02 2009-04-16 Alcon Inc Ophthalmic and otorhinolaryngological device materials containing an alkylphenol ethoxylate
TWI426931B (zh) 2007-10-03 2014-02-21 Alcon Inc 眼科與耳鼻喉科裝置材料（一）
TWI426932B (zh) 2007-10-05 2014-02-21 Alcon Inc 眼科與耳鼻喉科裝置材料（三）
TW201000155A (en) 2008-05-06 2010-01-01 Alcon Inc High refractive index ophthalmic device materials
ES2526253T3 (es) 2009-08-24 2015-01-08 Novartis Ag Materiales para dispositivos oftálmicos y otorrinolaringológicos

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693095A (en) * 1995-06-07 1997-12-02 Alcon Laboratories, Inc. High refractive index ophthalmic lens materials
CN1290352A (zh) * 1998-04-15 2001-04-04 阿尔康实验室公司 高折射率眼科装置用材料
JP2005160565A (ja) * 2003-11-28 2005-06-23 Nidek Co Ltd 眼内レンズ
CN101137684A (zh) * 2005-03-09 2008-03-05 Hoya株式会社 (甲基)丙烯酸酯化合物及其制备方法、(甲基)丙烯酸酯共聚物及其制备方法以及软性眼内透镜
CN1995077A (zh) * 2006-01-05 2007-07-11 苏州六六明人工晶体有限公司 疏水性透明丙烯酸酯共聚物及其应用
CN101563115A (zh) * 2006-07-21 2009-10-21 爱尔康公司 低粘着性的眼用和耳鼻喉用器件材料
CN101495887A (zh) * 2006-07-28 2009-07-29 先进视觉科学有限公司 眼科用水塑化高折射率聚合物
CN101617248A (zh) * 2007-02-23 2009-12-30 埃西勒国际通用光学公司 制造涂覆有具有改进的粘附性和耐磨性的抗反射涂层或反光涂层的光学制品的方法
US20090093592A1 (en) * 2007-10-05 2009-04-09 Alcon, Inc. Ophthalmic and otorhinolaryngological device materials

Also Published As

Publication number Publication date
KR20130090873A (ko) 2013-08-14
MX2012015178A (es) 2013-01-24
CA2801076A1 (en) 2011-12-29
TW201206965A (en) 2012-02-16
CA2801076C (en) 2014-06-10
ES2523387T3 (es) 2014-11-25
JP2013529505A (ja) 2013-07-22
NZ603881A (en) 2014-02-28
CN102946913A (zh) 2013-02-27
ZA201209331B (en) 2014-02-26
TWI473823B (zh) 2015-02-21
AU2011271228B2 (en) 2013-09-12
US20110313518A1 (en) 2011-12-22
RU2571091C2 (ru) 2015-12-20
AU2011271228A1 (en) 2012-12-20
EP2582409A1 (en) 2013-04-24
WO2011163126A1 (en) 2011-12-29
RU2013102497A (ru) 2014-07-27
SG186289A1 (en) 2013-01-30
BR112012032626A2 (pt) 2016-10-25
IL223487A (en) 2014-07-31
US8449610B2 (en) 2013-05-28
AR081963A1 (es) 2012-10-31
PH12012502514A1 (en) 2017-08-09
EP2582409B1 (en) 2014-09-10
KR101353975B1 (ko) 2014-01-22
JP5363683B2 (ja) 2013-12-11

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Effective date of registration: 20191210

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Granted publication date: 20150107

Termination date: 20200620