CN102946913B - 具有降低反光的高折射率丙烯酸眼用器件材料 - Google Patents

具有降低反光的高折射率丙烯酸眼用器件材料 Download PDF

Info

Publication number
CN102946913B
CN102946913B CN201180030684.4A CN201180030684A CN102946913B CN 102946913 B CN102946913 B CN 102946913B CN 201180030684 A CN201180030684 A CN 201180030684A CN 102946913 B CN102946913 B CN 102946913B
Authority
CN
China
Prior art keywords
acrylate
methacrylate
device material
ophthalmic
ent device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201180030684.4A
Other languages
English (en)
Chinese (zh)
Other versions
CN102946913A (zh
Inventor
W·R·拉雷多
C·费瑞曼
T·A·卡拉甘
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Inc
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN102946913A publication Critical patent/CN102946913A/zh
Application granted granted Critical
Publication of CN102946913B publication Critical patent/CN102946913B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1602Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/16Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16Intraocular lenses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04Homopolymers or copolymers of esters
    • C08L33/14Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02Polyalkylene oxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/16Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Eyeglasses (AREA)
  • Prostheses (AREA)
CN201180030684.4A 2010-06-21 2011-06-20 具有降低反光的高折射率丙烯酸眼用器件材料 Expired - Fee Related CN102946913B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35696310P 2010-06-21 2010-06-21
US61/356,963 2010-06-21
PCT/US2011/041070 WO2011163126A1 (en) 2010-06-21 2011-06-20 High refractive index, acrylic ophthalmic device materials with reduced glistenings

Publications (2)

Publication Number Publication Date
CN102946913A CN102946913A (zh) 2013-02-27
CN102946913B true CN102946913B (zh) 2015-01-07

Family

ID=44485011

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180030684.4A Expired - Fee Related CN102946913B (zh) 2010-06-21 2011-06-20 具有降低反光的高折射率丙烯酸眼用器件材料

Country Status (19)

Country Link
US (1) US8449610B2 (https=)
EP (1) EP2582409B1 (https=)
JP (1) JP5363683B2 (https=)
KR (1) KR101353975B1 (https=)
CN (1) CN102946913B (https=)
AR (1) AR081963A1 (https=)
AU (1) AU2011271228B2 (https=)
BR (1) BR112012032626A2 (https=)
CA (1) CA2801076C (https=)
ES (1) ES2523387T3 (https=)
IL (1) IL223487A (https=)
MX (1) MX2012015178A (https=)
NZ (1) NZ603881A (https=)
PH (1) PH12012502514A1 (https=)
RU (1) RU2571091C2 (https=)
SG (1) SG186289A1 (https=)
TW (1) TWI473823B (https=)
WO (1) WO2011163126A1 (https=)
ZA (1) ZA201209331B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI517861B (zh) 2011-02-08 2016-01-21 諾華公司 低黏度疏水性眼科裝置材料
TWI513768B (zh) 2011-06-01 2015-12-21 Novartis Ag 疏水性丙烯酸系眼內水晶體材料
TWI551646B (zh) 2011-06-03 2016-10-01 諾華公司 疏水性丙烯酸系眼內水晶體材料
CN103183822B (zh) * 2011-12-28 2016-03-30 辽宁奥克化学股份有限公司 一种不饱和氨酯聚氧烷基醚及其制备方法
WO2013122584A1 (en) * 2012-02-15 2013-08-22 Novartis Ag Ophthalmic and otorhinolaryngological device materials containing a multi-arm peg macromer
GB201314455D0 (en) * 2013-08-13 2013-09-25 Contamac Ltd Monomers for use in a polymerizable composition and high refractive index polymer for opthalmic applications
CA2928011C (en) 2013-12-04 2019-03-26 Alcon Inc. Soft acrylic materials comprising a poly(phenylether)-containing monomer having a high refractive index and minimized glistening
WO2015170278A1 (en) 2014-05-07 2015-11-12 Tubitak A formulation and lens manufacturing process for the production of intraocular lens (iol)
WO2016100190A1 (en) * 2014-12-16 2016-06-23 Novartis Ag Low-water content acrylate-acrylamide copolymers for ophthalmic devices
US9864102B2 (en) 2014-12-16 2018-01-09 Novartis Ag Hydrophobic acrylate-acrylamide copolymers for ophthalmic devices
CA2971877C (en) 2015-02-16 2019-10-01 Alcon Inc. Wet-pack intraocular lens materials with high refractive index
CN105536053B (zh) * 2015-12-29 2018-10-02 哈尔滨工业大学 一种作为人工晶状体材料的亲水性形状记忆水凝胶
CN110088158A (zh) * 2016-08-05 2019-08-02 迈克罗欧普提克斯股份有限公司 聚合物装置及制造方法
EP3363794A1 (en) * 2017-02-15 2018-08-22 Merck Patent GmbH Bis-compounds for optically active devices
EP3634508B1 (en) * 2017-06-05 2021-10-27 Alcon Inc. High refractive index, high abbe number intraocular lens materials
WO2019126080A1 (en) * 2017-12-18 2019-06-27 Dan Sachs Devices, systems and methods for therapeutic muscle stimulation
TW201927263A (zh) 2017-12-18 2019-07-16 瑞士商諾華公司 觸覺力分佈得到改善的眼內透鏡平台
TW201927262A (zh) 2017-12-20 2019-07-16 瑞士商諾華公司 具有前偏置光學設計之眼內透鏡
CN111491588A (zh) * 2018-01-31 2020-08-04 株式会社目立康 人工晶状体
JP7728703B2 (ja) * 2019-03-07 2025-08-25 テレオン ホールディング ビー.ヴイ. 眼内レンズ組成物
JP2022531027A (ja) 2019-05-03 2022-07-06 ジョンソン・アンド・ジョンソン・サージカル・ビジョン・インコーポレイテッド 高反応性指数、高アッベ組成物
US11708440B2 (en) 2019-05-03 2023-07-25 Johnson & Johnson Surgical Vision, Inc. High refractive index, high Abbe compositions
US11795252B2 (en) 2020-10-29 2023-10-24 Johnson & Johnson Surgical Vision, Inc. Compositions with high refractive index and Abbe number
CN113527567B (zh) * 2021-07-26 2023-01-24 康小林 疏水性无闪光点高折光率眼科聚合物材料

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693095A (en) * 1995-06-07 1997-12-02 Alcon Laboratories, Inc. High refractive index ophthalmic lens materials
CN1290352A (zh) * 1998-04-15 2001-04-04 阿尔康实验室公司 高折射率眼科装置用材料
JP2005160565A (ja) * 2003-11-28 2005-06-23 Nidek Co Ltd 眼内レンズ
CN1995077A (zh) * 2006-01-05 2007-07-11 苏州六六明人工晶体有限公司 疏水性透明丙烯酸酯共聚物及其应用
CN101137684A (zh) * 2005-03-09 2008-03-05 Hoya株式会社 (甲基)丙烯酸酯化合物及其制备方法、(甲基)丙烯酸酯共聚物及其制备方法以及软性眼内透镜
US20090093592A1 (en) * 2007-10-05 2009-04-09 Alcon, Inc. Ophthalmic and otorhinolaryngological device materials
CN101495887A (zh) * 2006-07-28 2009-07-29 先进视觉科学有限公司 眼科用水塑化高折射率聚合物
CN101563115A (zh) * 2006-07-21 2009-10-21 爱尔康公司 低粘着性的眼用和耳鼻喉用器件材料
CN101617248A (zh) * 2007-02-23 2009-12-30 埃西勒国际通用光学公司 制造涂覆有具有改进的粘附性和耐磨性的抗反射涂层或反光涂层的光学制品的方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304895A (en) 1973-06-20 1981-12-08 Wesley-Jessen, Inc. Ultraviolet absorbing corneal contact lenses
US4528311A (en) 1983-07-11 1985-07-09 Iolab Corporation Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxyphenyl-2H-benzotriazoles
US5290892A (en) 1990-11-07 1994-03-01 Nestle S.A. Flexible intraocular lenses made from high refractive index polymers
US5331073A (en) 1992-11-09 1994-07-19 Allergan, Inc. Polymeric compositions and intraocular lenses made from same
US5470932A (en) 1993-10-18 1995-11-28 Alcon Laboratories, Inc. Polymerizable yellow dyes and their use in opthalmic lenses
US6353069B1 (en) 1998-04-15 2002-03-05 Alcon Manufacturing, Ltd. High refractive index ophthalmic device materials
US6281319B1 (en) * 1999-04-12 2001-08-28 Surgidev Corporation Water plasticized high refractive index polymer for ophthalmic applications
WO2001018396A1 (en) * 1999-09-03 2001-03-15 Baxter International Inc. Programmable, fluid pressure actuated blood processing systems and methods
ATE291045T1 (de) 1999-09-07 2005-04-15 Alcon Inc Material für faltbare ophtalmische und otorhinolaryngologische gegenstände
FR2808201B1 (fr) 2000-04-26 2002-07-26 Ass Pour Les Transferts De Tec Lentille souple intraoculaire a caracteristiques d'hydrophilicite ameliorees et son procede d'obtention
US8153156B2 (en) 2002-11-13 2012-04-10 The United States Of America As Represented By The Department Of Veteran Affairs Hydrogel nanocompsites for ophthalmic applications
US7157538B2 (en) * 2004-08-13 2007-01-02 Alcon, Inc. Covalently-bound, hydrophilic coating compositions for surgical implants
US7789509B2 (en) 2006-06-01 2010-09-07 Advanced Vision Science, Inc. Non- or reduced glistenings intraocular lens and method of manufacturing same
WO2007149083A1 (en) 2006-06-21 2007-12-27 Bausch & Lomb Incorporated Polymerizable surfactants and their use as device forming comonomers
US7714039B2 (en) 2006-07-21 2010-05-11 Alcon, Inc. Low-tack ophthalmic and otorhinolaryngological device materials
ES2365290T3 (es) 2007-07-25 2011-09-28 Alcon, Inc. Materiales para dispositivo oftálmico de alto índice de refracción.
TW200920330A (en) 2007-10-02 2009-05-16 Alcon Inc Ophthalmic and otorhinolaryngological device materials containing an alkyl ethoxylate
TW200916130A (en) 2007-10-02 2009-04-16 Alcon Inc Ophthalmic and otorhinolaryngological device materials containing an alkylphenol ethoxylate
TWI426931B (zh) 2007-10-03 2014-02-21 Alcon Inc 眼科與耳鼻喉科裝置材料(一)
TWI426932B (zh) 2007-10-05 2014-02-21 Alcon Inc 眼科與耳鼻喉科裝置材料(三)
TW201000155A (en) 2008-05-06 2010-01-01 Alcon Inc High refractive index ophthalmic device materials
AU2010289896B2 (en) 2009-08-24 2013-08-29 Alcon Inc. Ophthalmic and otorhinolaryngological device materials

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693095A (en) * 1995-06-07 1997-12-02 Alcon Laboratories, Inc. High refractive index ophthalmic lens materials
CN1290352A (zh) * 1998-04-15 2001-04-04 阿尔康实验室公司 高折射率眼科装置用材料
JP2005160565A (ja) * 2003-11-28 2005-06-23 Nidek Co Ltd 眼内レンズ
CN101137684A (zh) * 2005-03-09 2008-03-05 Hoya株式会社 (甲基)丙烯酸酯化合物及其制备方法、(甲基)丙烯酸酯共聚物及其制备方法以及软性眼内透镜
CN1995077A (zh) * 2006-01-05 2007-07-11 苏州六六明人工晶体有限公司 疏水性透明丙烯酸酯共聚物及其应用
CN101563115A (zh) * 2006-07-21 2009-10-21 爱尔康公司 低粘着性的眼用和耳鼻喉用器件材料
CN101495887A (zh) * 2006-07-28 2009-07-29 先进视觉科学有限公司 眼科用水塑化高折射率聚合物
CN101617248A (zh) * 2007-02-23 2009-12-30 埃西勒国际通用光学公司 制造涂覆有具有改进的粘附性和耐磨性的抗反射涂层或反光涂层的光学制品的方法
US20090093592A1 (en) * 2007-10-05 2009-04-09 Alcon, Inc. Ophthalmic and otorhinolaryngological device materials

Also Published As

Publication number Publication date
US20110313518A1 (en) 2011-12-22
TWI473823B (zh) 2015-02-21
NZ603881A (en) 2014-02-28
BR112012032626A2 (pt) 2016-10-25
IL223487A (en) 2014-07-31
AR081963A1 (es) 2012-10-31
SG186289A1 (en) 2013-01-30
KR101353975B1 (ko) 2014-01-22
EP2582409A1 (en) 2013-04-24
AU2011271228A1 (en) 2012-12-20
AU2011271228B2 (en) 2013-09-12
ES2523387T3 (es) 2014-11-25
RU2013102497A (ru) 2014-07-27
MX2012015178A (es) 2013-01-24
KR20130090873A (ko) 2013-08-14
CN102946913A (zh) 2013-02-27
RU2571091C2 (ru) 2015-12-20
WO2011163126A1 (en) 2011-12-29
JP5363683B2 (ja) 2013-12-11
CA2801076A1 (en) 2011-12-29
ZA201209331B (en) 2014-02-26
CA2801076C (en) 2014-06-10
PH12012502514A1 (en) 2017-08-09
EP2582409B1 (en) 2014-09-10
US8449610B2 (en) 2013-05-28
JP2013529505A (ja) 2013-07-22
TW201206965A (en) 2012-02-16

Similar Documents

Publication Publication Date Title
CN102946913B (zh) 具有降低反光的高折射率丙烯酸眼用器件材料
US8466209B2 (en) Hydrophobic acrylic intraocular lens materials
CN103596602B (zh) 疏水性丙烯酸眼内透镜材料
WO2009137525A1 (en) High refractive index ophthalmic device materials
RU2728693C1 (ru) Материалы для интраокулярной линзы с высоким показателем преломления и высоким числом аббе
CN104620137A (zh) 具有降低粘性的高折射率眼科装置材料
NZ617790B2 (en) Hydrophobic acrylic intraocular lens materials

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20191210

Address after: Fribourg

Patentee after: Alcon Company

Address before: Basel

Patentee before: Nowatis Corporation

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150107

Termination date: 20200620