CN102666492B - 制备5-氟-1-烷基-3-氟烷基-1h-吡唑-4-碳酰氯的方法 - Google Patents

制备5-氟-1-烷基-3-氟烷基-1h-吡唑-4-碳酰氯的方法 Download PDF

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Publication number
CN102666492B
CN102666492B CN201080052388.XA CN201080052388A CN102666492B CN 102666492 B CN102666492 B CN 102666492B CN 201080052388 A CN201080052388 A CN 201080052388A CN 102666492 B CN102666492 B CN 102666492B
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CN
China
Prior art keywords
alkyl
formula
fluoroalkyl
fluoro
pyrazoles
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CN201080052388.XA
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English (en)
Chinese (zh)
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CN102666492A (zh
Inventor
瑟基·帕泽尼克
诺伯特·刘
马克·蔻斯特纳
金特·巴特斯
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Bayer CropScience AG
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Bayer Intellectual Property GmbH
Bayer CropScience AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Finger-Pressure Massage (AREA)
  • Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN201080052388.XA 2009-11-19 2010-11-17 制备5-氟-1-烷基-3-氟烷基-1h-吡唑-4-碳酰氯的方法 Active CN102666492B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26264109P 2009-11-19 2009-11-19
US61/262,641 2009-11-19
EP09176426A EP2325173A1 (de) 2009-11-19 2009-11-19 Verfahren zum Herstellen von 5-Fluor-1-alkyl-3-fluoralkyl-1H-pyrazol-4-carbonsäurechloriden
EP09176426.6 2009-11-19
PCT/EP2010/067630 WO2011061205A1 (de) 2009-11-19 2010-11-17 Verfahren zum herstellen von 5-fluor-1-alkyl-3-fluoralkyl-1h-pyrazol-4-carbonsäurechloriden

Publications (2)

Publication Number Publication Date
CN102666492A CN102666492A (zh) 2012-09-12
CN102666492B true CN102666492B (zh) 2016-03-23

Family

ID=42077022

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080052388.XA Active CN102666492B (zh) 2009-11-19 2010-11-17 制备5-氟-1-烷基-3-氟烷基-1h-吡唑-4-碳酰氯的方法

Country Status (13)

Country Link
US (2) US8436191B2 (https=)
EP (2) EP2325173A1 (https=)
JP (1) JP5802213B2 (https=)
KR (2) KR101635046B1 (https=)
CN (1) CN102666492B (https=)
BR (1) BR112012011961B1 (https=)
DK (1) DK2501682T3 (https=)
ES (1) ES2600864T3 (https=)
IL (1) IL219682A (https=)
IN (1) IN2012DN04414A (https=)
MX (2) MX2012005676A (https=)
TW (1) TWI510473B (https=)
WO (1) WO2011061205A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
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CN102421757A (zh) * 2009-05-15 2012-04-18 拜尔农科股份公司 杀真菌剂吡唑羧酰胺衍生物

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2325173A1 (de) 2009-11-19 2011-05-25 Bayer CropScience AG Verfahren zum Herstellen von 5-Fluor-1-alkyl-3-fluoralkyl-1H-pyrazol-4-carbonsäurechloriden
MX2012012085A (es) 2010-04-23 2012-11-29 Bayer Ip Gmbh Procedimiento para la preparacion de cloruros y fluoruros de 5-fluoro-1-alquil-3-fluoroalquil-1h-pirazol-4-carbonilo.
JP6101345B2 (ja) * 2012-05-14 2017-03-22 バイエル・クロップサイエンス・アクチェンゲゼルシャフト １−アルキル−３−フルオロアルキル−１ｈ−ピラゾール−４−カルボニルクロライド類の製造方法
ES2628332T3 (es) 2012-08-07 2017-08-02 Bayer Cropscience Ag Procedimiento de preparación de pirazoles carboxilatos que contienen perfluoroalquilos
ES2610380T3 (es) * 2013-01-17 2017-04-27 Bayer Cropscience Ag Procedimiento de preparación de 5-fluoro-1-metil-3-difluorometil-1H-pirazol-4-carbaldehído
JP6366722B2 (ja) * 2013-09-20 2018-08-01 バイエル・クロップサイエンス・アクチェンゲゼルシャフト ５−フルオロ−１−アルキル−３−フルオロアルキル−１ｈ−ピラゾール−４−カルボアルデヒドの製造方法
JP6462703B2 (ja) * 2014-01-24 2019-01-30 バイエル・クロップサイエンス・アクチェンゲゼルシャフト １−アルキル−３−ジフルオロメチル−５−フルオロ−１ｈ−ピラゾール−４−カルバルデヒド類及び１−アルキル−３−ジフルオロメチル−５−フルオロ−１ｈ−ピラゾール−４−カルボキシレート類を調製する方法
JP6431088B2 (ja) 2014-03-24 2018-11-28 バイエル・クロップサイエンス・アクチェンゲゼルシャフト α，α−ジハロアミン類およびケチミン類からの３，５−ビス（ハロアルキル）ピラゾール誘導体の製造方法
EP3015458A1 (en) * 2014-11-03 2016-05-04 Bayer CropScience AG Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from a,a-dihaloamines and ketimines
TWI705055B (zh) 2015-04-29 2020-09-21 德商拜耳作物科學公司 製備5-氟-1h-吡唑-4-羰基氟化物之方法
WO2020093715A1 (en) 2018-11-07 2020-05-14 Fujian Yongjing Technology Co., Ltd New process for manufacture of pyrazoles or pyrimidones
US20230167062A1 (en) 2019-10-29 2023-06-01 Shenyang Sinochem Agrochemicals R&D Co., Ltd. Amide compound containing substituted acetophenone structural fragments and preparation method and application thereof
WO2022233129A1 (en) 2021-05-05 2022-11-10 Fujian Yongjing Technology Co., Ltd New process for the synthesis of 5-fluoro-3- (difuoromethyl) -5-fluoro-1-methyl-1h-pyrazole-4-carboxylic acid derivatives and the free acid thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1405853A1 (en) * 2001-06-21 2004-04-07 Kumiai Chemical Industry Co., Ltd. Isoxazoline derivatives and herbicides
CN101600695A (zh) * 2007-01-18 2009-12-09 拜尔农作物科学股份公司 制备取代吡唑碳酰氯的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
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US5223526A (en) * 1991-12-06 1993-06-29 Monsanto Company Pyrazole carboxanilide fungicides and use
DE19544800A1 (de) * 1995-12-01 1997-06-05 Bayer Ag Verfahren zur Herstellung von 1,3-Dimethyl-5-fluor-pyrazol-4-carboxaniliden
JP4465133B2 (ja) * 2001-02-08 2010-05-19 クミアイ化学工業株式会社 イソオキサゾリン誘導体及びこれを有効成分とする除草剤
UA78071C2 (en) 2002-08-07 2007-02-15 Kumiai Chemical Industry Co Herbicidal composition
RU2346996C2 (ru) 2004-06-29 2009-02-20 ЮРОПИЭН НИКЕЛЬ ПиЭлСи Усовершенствованное выщелачивание основных металлов
AU2005273619B2 (en) 2004-08-18 2009-05-28 Pfizer Inc. Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
US7930013B2 (en) 2005-06-29 2011-04-19 Compumedics Limited Sensor assembly with conductive bridge
DE102005044451A1 (de) * 2005-09-17 2007-03-22 Bayer Cropscience Gmbh Verfahren zum Herstellen von 5-Fluor-1,3-dialkyl-1H-pyrazol-4-carbonsäurefluoriden
EP1767353B1 (en) * 2005-09-27 2011-04-20 FUJIFILM Corporation Lithographic printing method
AR056882A1 (es) 2006-02-01 2007-10-31 Bayer Cropscience Sa Derivados del fungicida n- cicloalquil- bencil- amida
EP2325173A1 (de) 2009-11-19 2011-05-25 Bayer CropScience AG Verfahren zum Herstellen von 5-Fluor-1-alkyl-3-fluoralkyl-1H-pyrazol-4-carbonsäurechloriden

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1405853A1 (en) * 2001-06-21 2004-04-07 Kumiai Chemical Industry Co., Ltd. Isoxazoline derivatives and herbicides
CN101600695A (zh) * 2007-01-18 2009-12-09 拜尔农作物科学股份公司 制备取代吡唑碳酰氯的方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102421757A (zh) * 2009-05-15 2012-04-18 拜尔农科股份公司 杀真菌剂吡唑羧酰胺衍生物
US9695126B2 (en) 2009-05-15 2017-07-04 Bayer Intellectual Property Gmbh Fungicide pyrazole carboxamides derivatives
CN102421757B (zh) * 2009-05-15 2017-10-24 拜尔农科股份公司 杀真菌剂吡唑羧酰胺衍生物

Also Published As

Publication number Publication date
TW201127817A (en) 2011-08-16
EP2501682A1 (de) 2012-09-26
US20110207940A1 (en) 2011-08-25
JP5802213B2 (ja) 2015-10-28
TWI510473B (zh) 2015-12-01
US20130165664A1 (en) 2013-06-27
DK2501682T3 (en) 2016-11-14
US8765971B2 (en) 2014-07-01
WO2011061205A1 (de) 2011-05-26
IL219682A (en) 2016-08-31
IL219682A0 (en) 2012-07-31
MX2012005676A (es) 2012-06-19
BR112012011961B1 (pt) 2018-05-08
KR20160054041A (ko) 2016-05-13
KR101749561B1 (ko) 2017-06-21
MX344246B (es) 2016-12-07
EP2325173A1 (de) 2011-05-25
IN2012DN04414A (https=) 2015-08-07
KR101635046B1 (ko) 2016-07-01
ES2600864T3 (es) 2017-02-13
EP2501682B1 (de) 2016-08-03
US8436191B2 (en) 2013-05-07
JP2013511485A (ja) 2013-04-04
BR112012011961A2 (pt) 2015-09-08
KR20120084325A (ko) 2012-07-27
CN102666492A (zh) 2012-09-12

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Effective date of registration: 20151026

Address after: German Monheim

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Applicant before: Bayer Cropscience AG

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Effective date of registration: 20181221

Address after: Germany's Rhine River Monheim

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Address before: German Monheim

Patentee before: Bayer Pharma Aktiengesellschaft