CN102652176B - 茎部加速的等温核酸扩增技术 - Google Patents
茎部加速的等温核酸扩增技术 Download PDFInfo
- Publication number
- CN102652176B CN102652176B CN201080035868.5A CN201080035868A CN102652176B CN 102652176 B CN102652176 B CN 102652176B CN 201080035868 A CN201080035868 A CN 201080035868A CN 102652176 B CN102652176 B CN 102652176B
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0910302.9 | 2009-06-15 | ||
| GBGB0910302.9A GB0910302D0 (en) | 2009-06-15 | 2009-06-15 | Nucleic acid amplification |
| PCT/GB2010/001169 WO2010146349A1 (en) | 2009-06-15 | 2010-06-15 | Stem accelerated isothermal nucleic acid amplification technology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102652176A CN102652176A (zh) | 2012-08-29 |
| CN102652176B true CN102652176B (zh) | 2016-09-28 |
Family
ID=40940851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080035868.5A Active CN102652176B (zh) | 2009-06-15 | 2010-06-15 | 茎部加速的等温核酸扩增技术 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9410190B2 (enExample) |
| EP (1) | EP2443253B1 (enExample) |
| JP (2) | JP5907864B2 (enExample) |
| CN (1) | CN102652176B (enExample) |
| AU (1) | AU2010261541B2 (enExample) |
| CA (1) | CA2765406C (enExample) |
| ES (1) | ES2589079T3 (enExample) |
| GB (1) | GB0910302D0 (enExample) |
| WO (1) | WO2010146349A1 (enExample) |
| ZA (1) | ZA201109493B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11111531B2 (en) | 2014-07-16 | 2021-09-07 | Tangen Biosciences, Inc. | Isothermal methods for amplifying nucleic acid samples |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5843614B2 (ja) | 2009-01-30 | 2016-01-13 | オックスフォード ナノポア テクノロジーズ リミテッド | 膜貫通配列決定における核酸構築物のためのアダプター |
| DK2633071T3 (en) | 2010-10-27 | 2017-01-30 | Harvard College | COMPOSITIONS OF "MAINTENANCE" PRIMER DUPLEXES AND METHODS OF USE |
| EP2714939B1 (en) | 2011-05-24 | 2015-04-15 | Elitech Holding B.V. | Detection of methicillin-resistant staphylococcus aureus |
| JP6298404B2 (ja) | 2011-07-25 | 2018-03-20 | オックスフォード ナノポール テクノロジーズ リミテッド | 膜貫通ポアを用いる二重鎖ポリヌクレオチド配列決定のためのヘアピンループ方法 |
| EP2875154B1 (en) | 2012-07-19 | 2017-08-23 | Oxford Nanopore Technologies Limited | SSB method for characterising a nucleic acid |
| GB201314695D0 (en) | 2013-08-16 | 2013-10-02 | Oxford Nanopore Tech Ltd | Method |
| AU2014224432B2 (en) | 2013-03-08 | 2019-10-24 | Oxford Nanopore Technologies Limited | Enzyme stalling method |
| US10450595B2 (en) | 2013-03-15 | 2019-10-22 | Theranos Ip Company, Llc | Nucleic acid amplification |
| WO2014145291A1 (en) | 2013-03-15 | 2014-09-18 | Theranos, Inc. | Nucleic acid amplification |
| SG11201507272RA (en) * | 2013-03-15 | 2015-10-29 | Theranos Inc | Nuclei acid amplification |
| WO2014151177A1 (en) | 2013-03-15 | 2014-09-25 | 3M Innovative Properties Company | Sample concentrator and method of use |
| CA2917206C (en) * | 2013-08-09 | 2021-09-21 | Genebio Systems, Inc. | Dna amplification via scissor-like structures (dasl) |
| SG11201601611WA (en) | 2013-09-06 | 2016-04-28 | Theranos Inc | Systems and methods for detecting infectious diseases |
| CN103497947B (zh) * | 2013-09-13 | 2015-08-12 | 浙江国际旅行卫生保健中心 | 一种体外新型快速环介导等温扩增方法、体外检测甲型h1n1流感病毒的试剂及方法 |
| CA2927315A1 (en) * | 2013-11-22 | 2015-05-28 | Theranos, Inc. | Nucleic acid amplification |
| EP3495506B1 (en) | 2013-12-11 | 2023-07-12 | AccuraGen Holdings Limited | Methods for detecting rare sequence variants |
| US11286519B2 (en) | 2013-12-11 | 2022-03-29 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| US11859246B2 (en) | 2013-12-11 | 2024-01-02 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| GB201403096D0 (en) | 2014-02-21 | 2014-04-09 | Oxford Nanopore Tech Ltd | Sample preparation method |
| US10716587B2 (en) | 2014-06-13 | 2020-07-21 | Surgis Medical Llc | Surgical device with light |
| US11559801B2 (en) | 2014-11-03 | 2023-01-24 | Tangen Biosciences, Inc. | Apparatus and method for cell, spore, or virus capture and disruption |
| ES2891085T3 (es) | 2015-01-30 | 2022-01-26 | Harvard College | Obtención de imágenes sin microscopio |
| GB2550712B (en) * | 2015-02-26 | 2021-01-13 | Hitachi High Tech Corp | Method for constructing hairpin-containing nucleic acid molecules for nanopore sequencing |
| US10260090B2 (en) | 2015-07-16 | 2019-04-16 | Arizona Board Of Regents On Behalf Of Arizona State University | Accelerated isothermal amplification of DNA |
| HK1259101A1 (zh) | 2015-10-09 | 2019-11-22 | Accuragen Holdings Limited | 用於富集扩增产物的方法及组合物 |
| US12163184B2 (en) | 2015-12-03 | 2024-12-10 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| CN116949140A (zh) | 2016-02-17 | 2023-10-27 | 哈佛学院院长及董事 | 分子编程工具 |
| WO2017201102A1 (en) | 2016-05-16 | 2017-11-23 | Accuragen Holdings Limited | Method of improved sequencing by strand identification |
| GB201609220D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
| CN107488656B (zh) * | 2016-06-13 | 2020-07-17 | 陆欣华 | 一种核酸等温自扩增方法 |
| WO2018035170A1 (en) | 2016-08-15 | 2018-02-22 | Accuragen Holdings Limited | Compositions and methods for detecting rare sequence variants |
| EP3568492B1 (en) * | 2017-01-10 | 2025-01-01 | President and Fellows of Harvard College | Multiplexed signal amplification |
| WO2019118912A1 (en) | 2017-12-14 | 2019-06-20 | Medicinal Genomics Corporation | Methods and kits for classifying cannabinoid production in cannabis plants |
| EP3743525A4 (en) | 2018-01-26 | 2021-09-29 | President and Fellows of Harvard College | PROXIMITY DETECTION METHODS AND COMPOSITIONS |
| GB201807793D0 (en) | 2018-05-14 | 2018-06-27 | Oxford Nanopore Tech Ltd | Method |
| CN112601823A (zh) | 2018-06-12 | 2021-04-02 | 安可济控股有限公司 | 用于形成连接产物的方法和组合物 |
| CN114045330B (zh) * | 2021-12-23 | 2024-02-09 | 川北医学院附属医院 | 一种基于滑动复制的核酸等温扩增方法 |
| CN118621045A (zh) * | 2024-08-14 | 2024-09-10 | 天健生物制药(天津)有限公司 | 基于lamp的鸟分枝杆菌检测的组合物和试剂盒 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101294222A (zh) * | 2007-04-26 | 2008-10-29 | 株式会社东芝 | 用于检测血清淀粉状蛋白a1(saa1)的基因型的核苷酸引物组和核苷酸探针 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5866336A (en) * | 1996-07-16 | 1999-02-02 | Oncor, Inc. | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| JP4918210B2 (ja) * | 2000-09-19 | 2012-04-18 | 栄研化学株式会社 | ポリヌクレオチドの合成方法 |
| WO2002090538A1 (en) | 2001-05-08 | 2002-11-14 | Eiken Kagaku Kabushiki Kaisha | Method of synthesizing nucleic acid |
| GB0218215D0 (en) | 2002-08-06 | 2002-09-11 | Tepnel Medical Ltd | Amplification of nucleic acids |
| WO2007025281A2 (en) | 2005-08-24 | 2007-03-01 | Applera Corporation | A method to quantify sirnas, mirnas and polymorphic mirnas |
| JP4580875B2 (ja) * | 2006-01-20 | 2010-11-17 | 株式会社東芝 | 核酸検出法のためのプライマーの設計方法 |
| JP2008029333A (ja) | 2006-07-03 | 2008-02-14 | Fujifilm Corp | 新規遺伝子増幅法に用いられるプライマー |
| JP2010505438A (ja) | 2006-10-09 | 2010-02-25 | オキシテック・リミテッド | 核酸配列を増幅および検出する方法 |
| US8748100B2 (en) | 2007-08-30 | 2014-06-10 | The Chinese University Of Hong Kong | Methods and kits for selectively amplifying, detecting or quantifying target DNA with specific end sequences |
-
2009
- 2009-06-15 GB GBGB0910302.9A patent/GB0910302D0/en not_active Ceased
-
2010
- 2010-06-15 US US13/377,704 patent/US9410190B2/en active Active
- 2010-06-15 EP EP10725825.3A patent/EP2443253B1/en active Active
- 2010-06-15 ES ES10725825.3T patent/ES2589079T3/es active Active
- 2010-06-15 AU AU2010261541A patent/AU2010261541B2/en active Active
- 2010-06-15 CN CN201080035868.5A patent/CN102652176B/zh active Active
- 2010-06-15 CA CA2765406A patent/CA2765406C/en active Active
- 2010-06-15 WO PCT/GB2010/001169 patent/WO2010146349A1/en not_active Ceased
- 2010-06-15 JP JP2012515553A patent/JP5907864B2/ja active Active
-
2011
- 2011-12-22 ZA ZA2011/09493A patent/ZA201109493B/en unknown
-
2015
- 2015-10-09 JP JP2015201347A patent/JP6106732B2/ja not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101294222A (zh) * | 2007-04-26 | 2008-10-29 | 株式会社东芝 | 用于检测血清淀粉状蛋白a1(saa1)的基因型的核苷酸引物组和核苷酸探针 |
Non-Patent Citations (2)
| Title |
|---|
| DNA环介导的恒温扩增法在快速鉴定病原微生物中的应用;王丽 等;《生命的化学》;20061231;第26卷(第5期);462-465 * |
| 环媒恒温核酸扩增法在病原微生物鉴定中的研究应用;王丽 等;《应用基础与工程科学学报》;20080831;第16卷(第4期);478-485 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11111531B2 (en) | 2014-07-16 | 2021-09-07 | Tangen Biosciences, Inc. | Isothermal methods for amplifying nucleic acid samples |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0910302D0 (en) | 2009-07-29 |
| JP2012529904A (ja) | 2012-11-29 |
| US9410190B2 (en) | 2016-08-09 |
| EP2443253A1 (en) | 2012-04-25 |
| ES2589079T3 (es) | 2016-11-10 |
| EP2443253B1 (en) | 2016-06-08 |
| ZA201109493B (en) | 2015-07-29 |
| JP2016041070A (ja) | 2016-03-31 |
| JP6106732B2 (ja) | 2017-04-05 |
| AU2010261541A1 (en) | 2012-02-02 |
| AU2010261541B2 (en) | 2016-03-10 |
| US20120157326A1 (en) | 2012-06-21 |
| CN102652176A (zh) | 2012-08-29 |
| CA2765406C (en) | 2019-02-26 |
| JP5907864B2 (ja) | 2016-04-26 |
| WO2010146349A1 (en) | 2010-12-23 |
| CA2765406A1 (en) | 2010-12-23 |
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| C06 | Publication | ||
| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |