CN102652176B - 茎部加速的等温核酸扩增技术 - Google Patents

茎部加速的等温核酸扩增技术 Download PDF

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CN102652176B
CN102652176B CN201080035868.5A CN201080035868A CN102652176B CN 102652176 B CN102652176 B CN 102652176B CN 201080035868 A CN201080035868 A CN 201080035868A CN 102652176 B CN102652176 B CN 102652176B
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primer
fragment
stem
ring
sequence
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CN102652176A (zh
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劳伦斯·C·第希
盖伊·柯德乐
奥尔加·甘德尔曼
凯瑟·J·迈克滚
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Lumora Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions

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  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201080035868.5A 2009-06-15 2010-06-15 茎部加速的等温核酸扩增技术 Active CN102652176B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0910302.9 2009-06-15
GBGB0910302.9A GB0910302D0 (en) 2009-06-15 2009-06-15 Nucleic acid amplification
PCT/GB2010/001169 WO2010146349A1 (en) 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology

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CN102652176A CN102652176A (zh) 2012-08-29
CN102652176B true CN102652176B (zh) 2016-09-28

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US (1) US9410190B2 (enExample)
EP (1) EP2443253B1 (enExample)
JP (2) JP5907864B2 (enExample)
CN (1) CN102652176B (enExample)
AU (1) AU2010261541B2 (enExample)
CA (1) CA2765406C (enExample)
ES (1) ES2589079T3 (enExample)
GB (1) GB0910302D0 (enExample)
WO (1) WO2010146349A1 (enExample)
ZA (1) ZA201109493B (enExample)

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EP3674422A3 (en) 2013-09-06 2020-09-16 Labrador Diagnostics LLC Systems and methods for detecting infectious diseases
CN103497947B (zh) * 2013-09-13 2015-08-12 浙江国际旅行卫生保健中心 一种体外新型快速环介导等温扩增方法、体外检测甲型h1n1流感病毒的试剂及方法
JP2017500020A (ja) * 2013-11-22 2017-01-05 セラノス， インコーポレイテッド 核酸増幅
US11859246B2 (en) 2013-12-11 2024-01-02 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
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US11286519B2 (en) 2013-12-11 2022-03-29 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
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EP3215260B1 (en) 2014-11-03 2020-01-15 Tangen Biosciences Inc. Apparatus and method for cell, spore, or virus capture and disruption
US11639522B2 (en) 2015-01-30 2023-05-02 President And Fellows Of Harvard College Microscope-free imaging
DE112016000293T5 (de) 2015-02-26 2017-09-21 Hitachi High-Technologies Corporation Verfahren zum konstruieren eines nucleinsäure-moleküls
US10260090B2 (en) 2015-07-16 2019-04-16 Arizona Board Of Regents On Behalf Of Arizona State University Accelerated isothermal amplification of DNA
HK1259101A1 (zh) * 2015-10-09 2019-11-22 Accuragen Holdings Limited 用於富集扩增产物的方法及组合物
EP3383994A4 (en) 2015-12-03 2019-08-28 Accuragen Holdings Limited METHOD AND COMPOSITIONS FOR FORMING LIGATION PRODUCTS
EP3916107B1 (en) 2016-02-17 2023-04-05 President and Fellows of Harvard College Molecular programming tools
EP3458586B1 (en) 2016-05-16 2022-12-28 Accuragen Holdings Limited Method of improved sequencing by strand identification
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
CN107488656B (zh) 2016-06-13 2020-07-17 陆欣华 一种核酸等温自扩增方法
JP6966052B2 (ja) 2016-08-15 2021-11-10 アキュラーゲン ホールディングス リミテッド 稀な配列変異体を検出するための組成物および方法
JP7116062B2 (ja) * 2017-01-10 2022-08-09 プレジデント アンド フェローズ オブ ハーバード カレッジ 多重化シグナル増幅
EP3724322A1 (en) 2017-12-14 2020-10-21 Medicinal Genomics Corporation Methods and kits for classifying cannabinoid production in cannabis plants
CN111630179B (zh) 2018-01-26 2024-07-19 哈佛学院院长及董事 邻近检测方法和组合物
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
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US12553080B2 (en) 2021-06-14 2026-02-17 Delta Electronics Int'l (Singapore) Pte Ltd Lamp primer set and method for amplifying nucleic acids using the same
CN114045330B (zh) * 2021-12-23 2024-02-09 川北医学院附属医院 一种基于滑动复制的核酸等温扩增方法
CN118621045A (zh) * 2024-08-14 2024-09-10 天健生物制药（天津）有限公司 基于lamp的鸟分枝杆菌检测的组合物和试剂盒
WO2026050948A1 (zh) * 2024-09-04 2026-03-12 深圳华大生命科学研究院 核酸文库的构建方法及应用

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Also Published As

Publication number Publication date
ES2589079T3 (es) 2016-11-10
CN102652176A (zh) 2012-08-29
EP2443253A1 (en) 2012-04-25
CA2765406A1 (en) 2010-12-23
WO2010146349A1 (en) 2010-12-23
AU2010261541B2 (en) 2016-03-10
US9410190B2 (en) 2016-08-09
EP2443253B1 (en) 2016-06-08
AU2010261541A1 (en) 2012-02-02
CA2765406C (en) 2019-02-26
ZA201109493B (en) 2015-07-29
JP5907864B2 (ja) 2016-04-26
JP6106732B2 (ja) 2017-04-05
JP2012529904A (ja) 2012-11-29
JP2016041070A (ja) 2016-03-31
GB0910302D0 (en) 2009-07-29
US20120157326A1 (en) 2012-06-21

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