CA2765406C - Stem accelerated isothermal nucleic acid amplification technology - Google Patents

Stem accelerated isothermal nucleic acid amplification technology Download PDF

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Publication number
CA2765406C
CA2765406C CA2765406A CA2765406A CA2765406C CA 2765406 C CA2765406 C CA 2765406C CA 2765406 A CA2765406 A CA 2765406A CA 2765406 A CA2765406 A CA 2765406A CA 2765406 C CA2765406 C CA 2765406C
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Canada
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primer
primers
stem
region
segment
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CA2765406A
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English (en)
French (fr)
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CA2765406A1 (en
Inventor
Laurence Carlo Tisi
Olga Gandelmann
Guy Kiddle
Cathal Joseph Mcelgunn
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Lumora Ltd
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Lumora Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2765406A 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology Active CA2765406C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0910302.9A GB0910302D0 (en) 2009-06-15 2009-06-15 Nucleic acid amplification
GB0910302.9 2009-06-15
PCT/GB2010/001169 WO2010146349A1 (en) 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology

Publications (2)

Publication Number Publication Date
CA2765406A1 CA2765406A1 (en) 2010-12-23
CA2765406C true CA2765406C (en) 2019-02-26

Family

ID=40940851

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2765406A Active CA2765406C (en) 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology

Country Status (10)

Country Link
US (1) US9410190B2 (enExample)
EP (1) EP2443253B1 (enExample)
JP (2) JP5907864B2 (enExample)
CN (1) CN102652176B (enExample)
AU (1) AU2010261541B2 (enExample)
CA (1) CA2765406C (enExample)
ES (1) ES2589079T3 (enExample)
GB (1) GB0910302D0 (enExample)
WO (1) WO2010146349A1 (enExample)
ZA (1) ZA201109493B (enExample)

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AU2011319755B2 (en) 2010-10-27 2017-02-23 President And Fellows Of Harvard College Compositions of toehold primer duplexes and methods of use
DK2714939T3 (en) * 2011-05-24 2015-06-29 Elitech Holding Bv DETECTION OF METHICILLIN-RESISTENT STAPHYLOCOCCUS AUREUS
IN2014DN00221A (enExample) 2011-07-25 2015-06-05 Oxford Nanopore Tech Ltd
WO2014013259A1 (en) 2012-07-19 2014-01-23 Oxford Nanopore Technologies Limited Ssb method
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
BR112015021788B1 (pt) 2013-03-08 2023-02-28 Oxford Nanopore Technologies Plc Métodos para mover uma ou mais helicases imobilizadas, para controlar o movimento de um polinucleotídeo alvo, para caracterizar um polinucleotídeo alvo e para controlar o carregamento de uma ou mais helicases em um polinucleotídeo alvo, uso de um poro de transmembrana e de um potencial aplicado e de um ou mais espaçadores, complexo, e, kit
JP2016521120A (ja) * 2013-03-15 2016-07-21 セラノス， インコーポレイテッド 核酸増幅
WO2014151177A1 (en) 2013-03-15 2014-09-25 3M Innovative Properties Company Sample concentrator and method of use
WO2015076919A1 (en) * 2013-11-22 2015-05-28 Theranos, Inc. Nucleic Acid Amplification
AU2014233145A1 (en) 2013-03-15 2015-09-17 Theranos Ip Company, Llc Nucleic acid amplification
US10450595B2 (en) 2013-03-15 2019-10-22 Theranos Ip Company, Llc Nucleic acid amplification
US10155977B2 (en) * 2013-08-09 2018-12-18 Genebio Systems, Inc. DNA amplification via scissor-like structures (DASL)
WO2015035260A1 (en) 2013-09-06 2015-03-12 Theranos, Inc. Systems and methods for detecting infectious diseases
CN103497947B (zh) * 2013-09-13 2015-08-12 浙江国际旅行卫生保健中心 一种体外新型快速环介导等温扩增方法、体外检测甲型h1n1流感病毒的试剂及方法
KR20240025725A (ko) 2013-12-11 2024-02-27 아큐라젠 홀딩스 리미티드 희귀 서열 변이를 검출하기 위한 조성물 및 방법
US11859246B2 (en) 2013-12-11 2024-01-02 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
US11286519B2 (en) 2013-12-11 2022-03-29 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
US10716587B2 (en) 2014-06-13 2020-07-21 Surgis Medical Llc Surgical device with light
WO2016011280A1 (en) 2014-07-16 2016-01-21 Tangen Biosciences, Inc. Isothermal methods for amplifying nucleic acid samples
US11559801B2 (en) 2014-11-03 2023-01-24 Tangen Biosciences, Inc. Apparatus and method for cell, spore, or virus capture and disruption
EP3974537A1 (en) 2015-01-30 2022-03-30 President and Fellows of Harvard College Microscope-free imaging
JP6560336B2 (ja) * 2015-02-26 2019-08-14 株式会社日立ハイテクノロジーズ 核酸分子の構築方法
US10260090B2 (en) 2015-07-16 2019-04-16 Arizona Board Of Regents On Behalf Of Arizona State University Accelerated isothermal amplification of DNA
MX2018004284A (es) 2015-10-09 2018-05-16 Accuragen Holdings Ltd Metodos y composiciones para el enriquecimiento de productos de amplificacion.
EP3383994A4 (en) 2015-12-03 2019-08-28 Accuragen Holdings Limited METHOD AND COMPOSITIONS FOR FORMING LIGATION PRODUCTS
EP3417078B1 (en) 2016-02-17 2021-05-05 President and Fellows of Harvard College Molecular programming tools
CN109511265B (zh) 2016-05-16 2023-07-14 安可济控股有限公司 通过链鉴定改进测序的方法
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
CN107488656B (zh) 2016-06-13 2020-07-17 陆欣华 一种核酸等温自扩增方法
WO2018035170A1 (en) 2016-08-15 2018-02-22 Accuragen Holdings Limited Compositions and methods for detecting rare sequence variants
US11492661B2 (en) 2017-01-10 2022-11-08 President And Fellows Of Harvard College Multiplexed signal amplification
US11035010B2 (en) 2017-12-14 2021-06-15 Medicinal Genomics Corporation Methods and kits for classifying cannabinoid production in cannabis plants
EP3743525A4 (en) 2018-01-26 2021-09-29 President and Fellows of Harvard College PROXIMITY DETECTION METHODS AND COMPOSITIONS
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
WO2019241290A1 (en) 2018-06-12 2019-12-19 Accuragen Holdings Limited Methods and compositions for forming ligation products
US12553080B2 (en) 2021-06-14 2026-02-17 Delta Electronics Int'l (Singapore) Pte Ltd Lamp primer set and method for amplifying nucleic acids using the same
CN114045330B (zh) * 2021-12-23 2024-02-09 川北医学院附属医院 一种基于滑动复制的核酸等温扩增方法
CN118621045A (zh) * 2024-08-14 2024-09-10 天健生物制药（天津）有限公司 基于lamp的鸟分枝杆菌检测的组合物和试剂盒
WO2026050948A1 (zh) * 2024-09-04 2026-03-12 深圳华大生命科学研究院 核酸文库的构建方法及应用

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US5866336A (en) * 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
ES2327712T3 (es) * 2000-09-19 2009-11-03 Eiken Kagaku Kabushiki Kaisha Procedimiento para sintetizar polinucleotidos.
JPWO2002090538A1 (ja) * 2001-05-08 2004-08-26 栄研化学株式会社 核酸を合成する方法
GB0218215D0 (en) 2002-08-06 2002-09-11 Tepnel Medical Ltd Amplification of nucleic acids
ATE532878T1 (de) 2005-08-24 2011-11-15 Life Technologies Corp Verfahren zur quantifizierung von sirnas, mirnas und polymorphen mirnas
JP4580875B2 (ja) * 2006-01-20 2010-11-17 株式会社東芝 核酸検出法のためのプライマーの設計方法
JP2008029333A (ja) 2006-07-03 2008-02-14 Fujifilm Corp 新規遺伝子増幅法に用いられるプライマー
JP2010505438A (ja) 2006-10-09 2010-02-25 オキシテック・リミテッド 核酸配列を増幅および検出する方法
JP4490988B2 (ja) 2007-04-26 2010-06-30 株式会社東芝 血清アミロイドａ１（ｓａａ１）の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法
US8748100B2 (en) 2007-08-30 2014-06-10 The Chinese University Of Hong Kong Methods and kits for selectively amplifying, detecting or quantifying target DNA with specific end sequences

Also Published As

Publication number Publication date
GB0910302D0 (en) 2009-07-29
ES2589079T3 (es) 2016-11-10
CA2765406A1 (en) 2010-12-23
AU2010261541A1 (en) 2012-02-02
JP6106732B2 (ja) 2017-04-05
AU2010261541B2 (en) 2016-03-10
JP2012529904A (ja) 2012-11-29
JP5907864B2 (ja) 2016-04-26
JP2016041070A (ja) 2016-03-31
ZA201109493B (en) 2015-07-29
CN102652176B (zh) 2016-09-28
EP2443253A1 (en) 2012-04-25
WO2010146349A1 (en) 2010-12-23
EP2443253B1 (en) 2016-06-08
US20120157326A1 (en) 2012-06-21
US9410190B2 (en) 2016-08-09
CN102652176A (zh) 2012-08-29

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