AU2010261541B2 - Stem accelerated isothermal nucleic acid amplification technology - Google Patents

Stem accelerated isothermal nucleic acid amplification technology Download PDF

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Publication number
AU2010261541B2
AU2010261541B2 AU2010261541A AU2010261541A AU2010261541B2 AU 2010261541 B2 AU2010261541 B2 AU 2010261541B2 AU 2010261541 A AU2010261541 A AU 2010261541A AU 2010261541 A AU2010261541 A AU 2010261541A AU 2010261541 B2 AU2010261541 B2 AU 2010261541B2
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Australia
Prior art keywords
primer
primers
stem
region
amplification
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AU2010261541A
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AU2010261541A1 (en
Inventor
Olga Gandelman
Guy Kiddle
Cathal Joseph Mcelgunn
Laurence Carlo Tisi
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Lumora Ltd
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Lumora Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2010261541A 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology Active AU2010261541B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0910302.9 2009-06-15
GBGB0910302.9A GB0910302D0 (en) 2009-06-15 2009-06-15 Nucleic acid amplification
PCT/GB2010/001169 WO2010146349A1 (en) 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology

Publications (2)

Publication Number Publication Date
AU2010261541A1 AU2010261541A1 (en) 2012-02-02
AU2010261541B2 true AU2010261541B2 (en) 2016-03-10

Family

ID=40940851

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010261541A Active AU2010261541B2 (en) 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology

Country Status (10)

Country Link
US (1) US9410190B2 (enExample)
EP (1) EP2443253B1 (enExample)
JP (2) JP5907864B2 (enExample)
CN (1) CN102652176B (enExample)
AU (1) AU2010261541B2 (enExample)
CA (1) CA2765406C (enExample)
ES (1) ES2589079T3 (enExample)
GB (1) GB0910302D0 (enExample)
WO (1) WO2010146349A1 (enExample)
ZA (1) ZA201109493B (enExample)

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DK2633071T3 (en) 2010-10-27 2017-01-30 Harvard College COMPOSITIONS OF "MAINTENANCE" PRIMER DUPLEXES AND METHODS OF USE
EP2714939B1 (en) 2011-05-24 2015-04-15 Elitech Holding B.V. Detection of methicillin-resistant staphylococcus aureus
JP6298404B2 (ja) 2011-07-25 2018-03-20 オックスフォード ナノポール テクノロジーズ リミテッド 膜貫通ポアを用いる二重鎖ポリヌクレオチド配列決定のためのヘアピンループ方法
EP2875154B1 (en) 2012-07-19 2017-08-23 Oxford Nanopore Technologies Limited SSB method for characterising a nucleic acid
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
AU2014224432B2 (en) 2013-03-08 2019-10-24 Oxford Nanopore Technologies Limited Enzyme stalling method
US10450595B2 (en) 2013-03-15 2019-10-22 Theranos Ip Company, Llc Nucleic acid amplification
WO2014145291A1 (en) 2013-03-15 2014-09-18 Theranos, Inc. Nucleic acid amplification
SG11201507272RA (en) * 2013-03-15 2015-10-29 Theranos Inc Nuclei acid amplification
WO2014151177A1 (en) 2013-03-15 2014-09-25 3M Innovative Properties Company Sample concentrator and method of use
CA2917206C (en) * 2013-08-09 2021-09-21 Genebio Systems, Inc. Dna amplification via scissor-like structures (dasl)
SG11201601611WA (en) 2013-09-06 2016-04-28 Theranos Inc Systems and methods for detecting infectious diseases
CN103497947B (zh) * 2013-09-13 2015-08-12 浙江国际旅行卫生保健中心 一种体外新型快速环介导等温扩增方法、体外检测甲型h1n1流感病毒的试剂及方法
CA2927315A1 (en) * 2013-11-22 2015-05-28 Theranos, Inc. Nucleic acid amplification
EP3495506B1 (en) 2013-12-11 2023-07-12 AccuraGen Holdings Limited Methods for detecting rare sequence variants
US11286519B2 (en) 2013-12-11 2022-03-29 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
US11859246B2 (en) 2013-12-11 2024-01-02 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
US10716587B2 (en) 2014-06-13 2020-07-21 Surgis Medical Llc Surgical device with light
CN106661600B (zh) 2014-07-16 2021-04-06 唐恩生物科技股份有限公司 用于扩增核酸样品的等温方法
US11559801B2 (en) 2014-11-03 2023-01-24 Tangen Biosciences, Inc. Apparatus and method for cell, spore, or virus capture and disruption
ES2891085T3 (es) 2015-01-30 2022-01-26 Harvard College Obtención de imágenes sin microscopio
GB2550712B (en) * 2015-02-26 2021-01-13 Hitachi High Tech Corp Method for constructing hairpin-containing nucleic acid molecules for nanopore sequencing
US10260090B2 (en) 2015-07-16 2019-04-16 Arizona Board Of Regents On Behalf Of Arizona State University Accelerated isothermal amplification of DNA
HK1259101A1 (zh) 2015-10-09 2019-11-22 Accuragen Holdings Limited 用於富集扩增产物的方法及组合物
US12163184B2 (en) 2015-12-03 2024-12-10 Accuragen Holdings Limited Methods and compositions for forming ligation products
CN116949140A (zh) 2016-02-17 2023-10-27 哈佛学院院长及董事 分子编程工具
WO2017201102A1 (en) 2016-05-16 2017-11-23 Accuragen Holdings Limited Method of improved sequencing by strand identification
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
CN107488656B (zh) * 2016-06-13 2020-07-17 陆欣华 一种核酸等温自扩增方法
WO2018035170A1 (en) 2016-08-15 2018-02-22 Accuragen Holdings Limited Compositions and methods for detecting rare sequence variants
EP3568492B1 (en) * 2017-01-10 2025-01-01 President and Fellows of Harvard College Multiplexed signal amplification
WO2019118912A1 (en) 2017-12-14 2019-06-20 Medicinal Genomics Corporation Methods and kits for classifying cannabinoid production in cannabis plants
EP3743525A4 (en) 2018-01-26 2021-09-29 President and Fellows of Harvard College PROXIMITY DETECTION METHODS AND COMPOSITIONS
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
CN112601823A (zh) 2018-06-12 2021-04-02 安可济控股有限公司 用于形成连接产物的方法和组合物
CN114045330B (zh) * 2021-12-23 2024-02-09 川北医学院附属医院 一种基于滑动复制的核酸等温扩增方法
CN118621045A (zh) * 2024-08-14 2024-09-10 天健生物制药(天津)有限公司 基于lamp的鸟分枝杆菌检测的组合物和试剂盒

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WO2002090538A1 (en) * 2001-05-08 2002-11-14 Eiken Kagaku Kabushiki Kaisha Method of synthesizing nucleic acid
EP1988178A2 (en) * 2007-04-26 2008-11-05 Kabushiki Kaisha Toshiba Nucleotide primer set and nucleotide probe for detecting genotype of serum amyloid A1(SAA1)

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WO2007025281A2 (en) 2005-08-24 2007-03-01 Applera Corporation A method to quantify sirnas, mirnas and polymorphic mirnas
JP4580875B2 (ja) * 2006-01-20 2010-11-17 株式会社東芝 核酸検出法のためのプライマーの設計方法
JP2008029333A (ja) 2006-07-03 2008-02-14 Fujifilm Corp 新規遺伝子増幅法に用いられるプライマー
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US8748100B2 (en) 2007-08-30 2014-06-10 The Chinese University Of Hong Kong Methods and kits for selectively amplifying, detecting or quantifying target DNA with specific end sequences

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2002090538A1 (en) * 2001-05-08 2002-11-14 Eiken Kagaku Kabushiki Kaisha Method of synthesizing nucleic acid
EP1988178A2 (en) * 2007-04-26 2008-11-05 Kabushiki Kaisha Toshiba Nucleotide primer set and nucleotide probe for detecting genotype of serum amyloid A1(SAA1)

Non-Patent Citations (1)

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Also Published As

Publication number Publication date
GB0910302D0 (en) 2009-07-29
JP2012529904A (ja) 2012-11-29
US9410190B2 (en) 2016-08-09
EP2443253A1 (en) 2012-04-25
ES2589079T3 (es) 2016-11-10
EP2443253B1 (en) 2016-06-08
ZA201109493B (en) 2015-07-29
JP2016041070A (ja) 2016-03-31
JP6106732B2 (ja) 2017-04-05
AU2010261541A1 (en) 2012-02-02
US20120157326A1 (en) 2012-06-21
CN102652176A (zh) 2012-08-29
CA2765406C (en) 2019-02-26
CN102652176B (zh) 2016-09-28
JP5907864B2 (ja) 2016-04-26
WO2010146349A1 (en) 2010-12-23
CA2765406A1 (en) 2010-12-23

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE NAME OF THE INVENTOR TO READ TISI, LAURENCE CARLO; GANDELMAN, OLGA; KIDDLE, GUY AND MCELGUNN, CATHAL JOSEPH

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