CN102647981B - 预防和治疗脑缺血的方法 - Google Patents

预防和治疗脑缺血的方法 Download PDF

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Publication number
CN102647981B
CN102647981B CN201080048363.2A CN201080048363A CN102647981B CN 102647981 B CN102647981 B CN 102647981B CN 201080048363 A CN201080048363 A CN 201080048363A CN 102647981 B CN102647981 B CN 102647981B
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tocotrienol quinone
alpha
cerebral
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cerebral ischemic
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Expired - Fee Related
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Chinese (zh)
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CN102647981A (zh
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G.M.米勒
V.基菲特斯
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Bio Electronics Technology
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Edison Phamaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201080048363.2A 2009-08-26 2010-08-24 预防和治疗脑缺血的方法 Expired - Fee Related CN102647981B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27526909P 2009-08-26 2009-08-26
US61/275,269 2009-08-26
PCT/US2010/046503 WO2011025785A1 (en) 2009-08-26 2010-08-24 Methods for the prevention and treatment of cerebral ischemia

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CN102647981A CN102647981A (zh) 2012-08-22
CN102647981B true CN102647981B (zh) 2016-09-28

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US (3) US20110207828A1 (https=)
EP (1) EP2470168B1 (https=)
JP (2) JP5785546B2 (https=)
CN (1) CN102647981B (https=)
AU (1) AU2010286704B2 (https=)
BR (1) BR112012004167A2 (https=)
CA (1) CA2772294C (https=)
DK (1) DK2470168T3 (https=)
EA (1) EA028677B1 (https=)
ES (1) ES2663709T3 (https=)
HU (1) HUE037592T2 (https=)
MX (1) MX337990B (https=)
NO (1) NO2470168T3 (https=)
PL (1) PL2470168T3 (https=)
PT (1) PT2470168T (https=)
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JP5785546B2 (ja) 2015-09-30
WO2011025785A1 (en) 2011-03-03
AU2010286704A1 (en) 2012-03-22
PT2470168T (pt) 2018-03-28
HUE037592T2 (hu) 2018-09-28
CA2772294C (en) 2018-08-21
ES2663709T3 (es) 2018-04-16
AU2010286704B2 (en) 2016-10-20
EA028677B1 (ru) 2017-12-29
MX2012002374A (es) 2012-04-10
DK2470168T3 (en) 2018-05-07
JP2013503168A (ja) 2013-01-31
PL2470168T3 (pl) 2018-06-29
US20170007553A1 (en) 2017-01-12
CA2772294A1 (en) 2011-03-03
BR112012004167A2 (pt) 2016-03-29
EA201200355A1 (ru) 2012-07-30
JP2015091899A (ja) 2015-05-14
NO2470168T3 (https=) 2018-06-30
US20110207828A1 (en) 2011-08-25
EP2470168A1 (en) 2012-07-04
US20180344667A1 (en) 2018-12-06
CN102647981A (zh) 2012-08-22
EP2470168B1 (en) 2018-01-31
MX337990B (es) 2016-03-30
SI2470168T1 (en) 2018-05-31

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