CN102640871A - Feed additive for aquatic livestock - Google Patents
Feed additive for aquatic livestock Download PDFInfo
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- CN102640871A CN102640871A CN2012101432107A CN201210143210A CN102640871A CN 102640871 A CN102640871 A CN 102640871A CN 2012101432107 A CN2012101432107 A CN 2012101432107A CN 201210143210 A CN201210143210 A CN 201210143210A CN 102640871 A CN102640871 A CN 102640871A
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- aquatic livestock
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Abstract
The invention discloses a feed additive for aquatic livestock, which is characterized by comprising taurine, radix astragali, rheum officinale, vitamin B12 and starch. By means of the technical scheme, the feed additive can increase bile secretory volume of the aquatic livestock, promote the biliary tract to be smooth, eliminate stasis of biliary, promote fat metabolism, fully digest matters of fat, fat-soluble vitamins, cholesterol and the like in foods, strengthen immune functions of organism of the aquatic livestock, improve immunity of the aquatic livestock and reduce absorptive amount of bacterial toxin in the aquatic livestock. By combining traditional Chinese and western medicines, the feed additive can regulate self recovery mechanisms of the aquatic livestock to protect livers, strengthen the livers and toughen the gallbladder.
Description
Technical field
The invention belongs to feed additive field, specifically, relate to the feed addictive of a kind of aquatic livestock.
Background technology
At present; In the aquaculture process because feed formula design is unreasonable, the long-term use of breeding water body ecological deterioration, chemicals; The people be fish for draw in the net to wait by force stress stimulation under, the aquatic livestock especially liver of grass carp, crucian etc. is caused very big damage, brings out the liver and gall syndrome of fish.For example, grass carp is a kind of in the aquatic livestock, also is one of China's aquatic products kind of extensively culturing; Along with the grass carp breed develops to high density, intensification direction; Also be accompanied by simultaneously a large amount of uses of antibiotic etc., occurred frequently-occurring liver and gall syndrome disease in recent years, the death rate is generally very high.
Commercially available aquatic livestock protects the liver protects courage class feed addictive, and composition is single, cures the symptoms, not the disease, and action effect is undesirable.
Summary of the invention
The technical problem that the present invention will solve is to overcome above-mentioned defective, provide a kind of can the enhancing body immunity function, improve the feed addictive of the aquatic livestock of animal immunizing power, the strong courage of strong liver.
For addressing the above problem, the technical scheme that the present invention adopted is:
The feed addictive of a kind of aquatic livestock is characterized in that, said additive comprises following composition:
Taurine, the Radix Astragali, rheum officinale, Cobastab
12And starch.
As a kind of improvement:
The feed addictive of a kind of aquatic livestock, said Taurine: the Radix Astragali: rheum officinale: Cobastab
12: the weight ratio of starch is 2: 1.5: 1.5: 0.5: 4.5.
As further improvement:
The said Radix Astragali utilizes Bacillus acidi lactici to carry out anaerobic fermentation, improved the content of Astragaloside IV and astragalus polyose in the Radix Astragali.
As further improving again:
Said rheum officinale utilizes Bacillus acidi lactici to carry out anaerobic fermentation, can alleviate the discomfort reaction that rheum officinale causes the animal stomach.
Wherein, the active ingredient of the Radix Astragali is Astragaloside IV and astragalus polyose.Astragaloside IV has enhance immunity power, enhanced energy, and antifatigue, anti-sudden change protects the liver, and suppresses the effect of osteoclast.Astragalus Root P.E has the protection liver, prevents the effect that hepatic glycogen reduces, and two kinds of astragalin ASI and SK can resist the hepatic injury that D-galactosamine and acetaminophen cause, Astragaloside IV is the malicious active ingredient of damaging of the anti-liver of the Radix Astragali, to preventing liver fibrosis certain effect is arranged.
Rheum officinale has the logical intestines that purge heat, and removing pattogenic heat from the blood and toxic material from the body is stimulated the menstrual flow by the stasis of blood.Be used for real hot constipation, stagnant stomachache, it is not well to rush down dysentery, jaundice with damp-heat pathogen, blood-head is told nosebleed, hot eyes, pharynx is swollen, abdominalgia with intestinal abscess, the carbuncle furunculosis that swells, hemostasis is through closing traumatic injury, the burning hot wound of harnessing the river outward; UGB, being used for blood-head has stasis of blood bleeder.
Taurine is claimed the 2-tarine again, and by separating in the cow-bezoar, chemical property is stable the earliest; Be dissolved in organic solvents such as ether; Be a kind of non-protein amino acid of sulfur-bearing, exist with free state in vivo, do not participate in the biosynthesis of albumen in the body; Though it is synthetic that taurine is not participated in protein, it is closely related with the metabolism of cystine, cysteine.
The effect of taurine is to combine with bile acid to form cholyltaurine in the liver, and taurocholate is essential to the absorption of lipid in the alimentary canal.Taurocholate can increase the dissolubility of lipid and cholesterol, removes cholestasia, reduces the cytotoxicity of some free bile acid, suppresses the formation of cholesterol stone, increases bile flow etc.; Taurine can promote pituitrin secretion, the activation pancreas function, thereby improve the state of organism endocrine system, to organism metabolism with useful adjusting; And have the enhancing that promotes organism immunity and an effect of antifatigue.
Cobastab
12Be cobalamin again, the Cobastab of occurring in nature
12All be that microorganism is synthetic, high animals and plants can not be made Cobastab
12Cobastab
12Be to need a kind of intestinal secretion thing (castle's intrinsic factor) to help the absorbed only a kind of vitamin of ability.
Cobastab
12Form with coenzyme exists, and can increase the utilization rate of folic acid, promotes the metabolism of carbohydrate, fat and protein, and fat metabolism acid makes fat, carbohydrate, protein suitably used Cobastab by health
12Also participate in the synthetic of picodna (DNA), the metabolism of fat, carbohydrate and protein increases the synthetic of nucleic acid and protein.
Because adopt technique scheme, the present invention can increase the choleresis of aquatic livestock, promote that biliary tract is unimpeded, eliminate cholestatis; Promote fat metabolism, fully materials such as the fat in the digest food, liposoluble vitamin, cholesterol; Strengthen the human body immune function of aquatic livestock, improve the immunity of aquatic livestock, reduce bacteriotoxin uptake in the aquatic livestock body, Chinese and Western combines, and regulates the liver-protective self-recovery mechanism of aquatic livestock, the strong courage of strong liver.
Below in conjunction with the specific embodiment the present invention is further specified.
The specific embodiment
Embodiment: the feed addictive of a kind of aquatic livestock, choose raw material, preparation 1000 gram feed addictives.Wherein the Radix Astragali 150 grams, rheum officinale 150 restrain, Taurine 200 restrains, Cobastab
1250 grams, starch 450 restrain, and process the feed addictive of 1000 grams after the mixing.
Wherein, earlier the 150 gram Radixs Astragali and 150 gram rheum officinales are carried out anaerobic fermentation with Bacillus acidi lactici respectively, the Radix Astragali after will fermenting again and rheum officinale and other raw material mix, and can make feed addictive of the present invention.
The present invention is that research object makes an experiment with the grass carp, through measuring specific growth rate, liver body ratio, liver transaminase, for the application of the present invention in the grass carp breeding process provides reference frame.
Test Example:
Select the long 12.5-13.0cm of body for use, grass carp 360 tails of body weight 38.1-38.9g are divided into 3 processed group at random, and every group 120 tail established 3 repetitions, and each repeats 40 tails.
Culture experiment carries out in indoor fiberglass circulation, and dissolved oxygen remains on 6mg/L, water temperature (28 ± 2) ℃.The test fish is tamed and dociled food after 10 days with basal feed, selects physical health, size evenly individual, divides into groups by experimental design.Duration of test 8:00 every day and 18:00 respectively throw something and feed once, and day throwing rate of raising is 2--3%, and test was carried out 30 days.
Control group (C) basal diet of throwing something and feeding, prescription and trophic level are seen table 1, add additive of the present invention by 400mg/kg and 800mg/kg respectively in the daily ration of test group T1 and T2.
Table 1 basal diet is formed and trophic level
Testing index:
Off-test 8:00 on the same day weighs, record feedstuff feeding amount, the following index of sampling and measuring simultaneously.The growth performance index:
Be respectively specific growth rate, feed coefficient, liver body ratio.
Specific growth rate=(all first body weight of the equal opisthosoma weight-In of In tail tail) * 100/ test fate;
Feed coefficient=tail daily ration total amount/(equal opisthosoma weight-tail of tail all just body weight) of all ingesting;
Liver body ratio=liver weight/body weight * 100%.
Serum aminotransferase activity:
Transaminase comprises ALT (ALT) and aspartate aminotransferase (AST), and the improvement King's method is adopted in determination of activity.
Data statistics and processing:
One-Way ANOVA carries out variance analysis in the test data employing SPSS11.5 statistical software, and carries out the Duncan multiple ratio.
Result of the test:
The feed addictive of the present invention of variable concentrations is to the influence of grass carp growth performance and efficiency of feed utilization in the daily ration:
Can find out that from table 2 specific growth rate that adds the test group grass carp of feed addictive of the present invention in the daily ration is significantly higher than control group (P<0.05), but does not form significant difference (P>0.05) between the test group.The interpolation of feed addictive of the present invention does not produce appreciable impact (P>0.05) to the feed coefficient of grass carp, only raises to some extent in the T2 test group.
The interpolation of feed addictive of the present invention influences significant difference (P<0.05) to grass carp liver body ratio; The liver body of test group grass carp is than being significantly higher than the control group (P<0.05) that does not add feed addictive of the present invention, and the liver body ratio of the high concentration T2 group grass carp of adding is significantly higher than T1 group (P<0.05).
Table 2 feed addictive according to the invention is to the influence of grass carp growth, feed conversion and liver body ratio
Annotate: same column data shoulder mark different letter representation significant differences (P<0.05), the alphabetical shoulder mark of nothing expression difference is remarkable (P>0.05) not, and following table is together.
The feed addictive of the present invention of variable concentrations is to the influence of the transaminase activity in the grass carp serum in the daily ration:
Compare with control group, the interpolation of feed addictive of the present invention has significantly reduced glutamic-pyruvic transaminase (ALT) and the glutamic-oxalacetic transaminease (AST) active (P<0.05) in the grass carp serum, but difference not remarkable (P>0.05) between T1 group and the T2 group.
Table 3 feed addictive according to the invention is to grass carp Serum ALT and the active influence of AST
Conclusion:
The feed addictive of the present invention that adds 400mg/kg in the daily ration promptly can effectively improve the growth performance of grass carp; The feed addictive of the present invention of higher concentration also is the growth formation conspicuousness influence to grass carp; Difference is not remarkable but the feed coefficient of respectively organizing grass carp is compared; Only reduced by 10% in 800mg/kg interpolation group; The quick growth of pointing out the use of feed addictive of the present invention to help grass carp, very not remarkable to the effect of feed conversion aspect, also need the test of longer time to observe.
But use the liver body of the grass carp of feed addictive of the present invention to reduce than remarkable; Testing used daily ration is high protein ration; Crude protein content reaches 32.23%, and a large amount of absorptions of high protein promote the quick growth of grass carp, has also strengthened the burden of liver of grass carp simultaneously; Part protein transduction turns to fat accumulation in the liver position, causes hepatomegaly.Feed addictive of the present invention uses the situation of obviously having improved the grass carp liver.
Glutami-oxaloacetic transaminase (AST) and glutamic-pyruvic transaminase (ALT) are two important aminopherases in the amino acid metabolism process.ALT mainly plays transamination in the course of reaction of catalysis KG and aspartic acid generation glutamic acid and oxaloacetic acid, and AST mainly plays transamination in the course of reaction of catalysis KG and alanine generation glutamic acid and pyruvic acid.When the physiological function of animal is under the normal condition, ALT and AST mainly are present in the cell, and the activity in the serum is very low.In each histoorgan, the highest with the activity in cardiac muscle cell and the liver cell.But when these histocytes are impaired; Having a large amount of glutamic-oxalacetic transamineases and paddy third Cyklokapren overflows in the cell and gets into blood; These two kinds of transaminase activities in the serum are raise, therefore judge the function status of histoorgan such as liver usually according to the variation of these two kinds of transaminase activities in the serum.Add the activity that feed addictive group of the present invention has obviously reduced serum alt and AST in this test in the daily ration, point out the use of feed addictive of the present invention to reduce the damage of test group grass carp hepatocyte.
Feed addictive of the present invention can effectively strengthen the liver function of grass carp, and minimizing fat is accumulated liver, and the protection liver is avoided damage, prevention fatty liver, the growth performance of raising grass carp.
Claims (4)
1. the feed addictive of an aquatic livestock is characterized in that, said additive comprises following composition:
Taurine, the Radix Astragali, rheum officinale, Cobastab
12And starch.
2. the feed addictive of a kind of aquatic livestock according to claim 1 is characterized in that: said Taurine: the Radix Astragali: rheum officinale: Cobastab
12: the weight ratio of starch is 2: 1.5: 1.5: 0.5: 4.5.
3. the feed addictive of a kind of aquatic livestock according to claim 1 and 2, it is characterized in that: the said Radix Astragali utilizes Bacillus acidi lactici to carry out anaerobic fermentation.
4. the feed addictive of a kind of aquatic livestock according to claim 1 and 2, it is characterized in that: said rheum officinale utilizes Bacillus acidi lactici to carry out anaerobic fermentation.
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CN105614176A (en) * | 2016-03-02 | 2016-06-01 | 怀远县渔业科技发展有限责任公司 | Feed additive for oxtail-fish artificial breeding |
CN105614063A (en) * | 2016-03-02 | 2016-06-01 | 怀远县渔业科技发展有限责任公司 | Additive special for artificial sole culturing feed |
CN105614064A (en) * | 2016-03-02 | 2016-06-01 | 怀远县渔业科技发展有限责任公司 | Method for preparing oxtail-fish artificial-breeding feed additive |
CN105639207A (en) * | 2016-03-07 | 2016-06-08 | 怀远县渔业科技发展有限责任公司 | Feed additives capable of increasing breeding ability of pelteobagrus fulvidraco |
CN105661036A (en) * | 2016-03-07 | 2016-06-15 | 怀远县渔业科技发展有限责任公司 | Special additive for artificial breeding feed of euchiloglanis kishinouyei kimura |
CN105707517A (en) * | 2016-03-07 | 2016-06-29 | 怀远县渔业科技发展有限责任公司 | Preparation method of additive special for artificial breeding feed of Euchiloglanis kishinouyei Kimura |
CN105707515A (en) * | 2016-03-07 | 2016-06-29 | 怀远县渔业科技发展有限责任公司 | Preparation method of special additive for Leucosoma chinensis artificial breeding feed |
CN105707516A (en) * | 2016-03-07 | 2016-06-29 | 怀远县渔业科技发展有限责任公司 | Special additive for Leucosoma chinensis artificial breeding feed |
CN105746882A (en) * | 2016-03-02 | 2016-07-13 | 怀远县渔业科技发展有限责任公司 | Preparation method of special additive for artificial culture feed of long lee fish |
CN105746948A (en) * | 2016-03-07 | 2016-07-13 | 怀远县渔业科技发展有限责任公司 | Preparation method of feed additive to improve breeding ability of yellow-head catfish |
CN105767509A (en) * | 2016-03-07 | 2016-07-20 | 怀远县渔业科技发展有限责任公司 | Special euchiloglanis kishinouyei trap bait |
CN109198266A (en) * | 2018-09-27 | 2019-01-15 | 清远海贝生物技术有限公司 | A kind of compound premix and its preparation method and application increasing strong fish enteron aisle |
CN110326722A (en) * | 2019-06-03 | 2019-10-15 | 佛山市南海区杰大饲料有限公司 | A kind of Red Star spot expanding compound feed and preparation method thereof |
CN113995059A (en) * | 2021-10-11 | 2022-02-01 | 珠海市德海生物科技有限公司 | Feed additive for improving anti-stress capability of sea bass and preparation method thereof |
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CN105614063A (en) * | 2016-03-02 | 2016-06-01 | 怀远县渔业科技发展有限责任公司 | Additive special for artificial sole culturing feed |
CN105614064A (en) * | 2016-03-02 | 2016-06-01 | 怀远县渔业科技发展有限责任公司 | Method for preparing oxtail-fish artificial-breeding feed additive |
CN105746882A (en) * | 2016-03-02 | 2016-07-13 | 怀远县渔业科技发展有限责任公司 | Preparation method of special additive for artificial culture feed of long lee fish |
CN105707515A (en) * | 2016-03-07 | 2016-06-29 | 怀远县渔业科技发展有限责任公司 | Preparation method of special additive for Leucosoma chinensis artificial breeding feed |
CN105707517A (en) * | 2016-03-07 | 2016-06-29 | 怀远县渔业科技发展有限责任公司 | Preparation method of additive special for artificial breeding feed of Euchiloglanis kishinouyei Kimura |
CN105661036A (en) * | 2016-03-07 | 2016-06-15 | 怀远县渔业科技发展有限责任公司 | Special additive for artificial breeding feed of euchiloglanis kishinouyei kimura |
CN105707516A (en) * | 2016-03-07 | 2016-06-29 | 怀远县渔业科技发展有限责任公司 | Special additive for Leucosoma chinensis artificial breeding feed |
CN105639207A (en) * | 2016-03-07 | 2016-06-08 | 怀远县渔业科技发展有限责任公司 | Feed additives capable of increasing breeding ability of pelteobagrus fulvidraco |
CN105746948A (en) * | 2016-03-07 | 2016-07-13 | 怀远县渔业科技发展有限责任公司 | Preparation method of feed additive to improve breeding ability of yellow-head catfish |
CN105767509A (en) * | 2016-03-07 | 2016-07-20 | 怀远县渔业科技发展有限责任公司 | Special euchiloglanis kishinouyei trap bait |
CN109198266A (en) * | 2018-09-27 | 2019-01-15 | 清远海贝生物技术有限公司 | A kind of compound premix and its preparation method and application increasing strong fish enteron aisle |
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CN113995059A (en) * | 2021-10-11 | 2022-02-01 | 珠海市德海生物科技有限公司 | Feed additive for improving anti-stress capability of sea bass and preparation method thereof |
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Effective date of registration: 20160829 Address after: 261102, Shandong Weifang Economic Development Zone, Yang Yang Street, small river village Patentee after: Weifang Lehman Biological Technology Co., Ltd. Address before: 261102 Weifang, Hanting, China, the high street in Weifang entrepreneurial base Biological Technology Co., Ltd. Lehman Patentee before: Yang Hongxing |