CN101715893A - Pure natural piglet immunological enhancement feed additive and application thereof - Google Patents
Pure natural piglet immunological enhancement feed additive and application thereof Download PDFInfo
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Abstract
The invention relates to a pure natural piglet immunological enhancement feed additive and application thereof. The feed additive is characterized by comprising the following raw material components in percentage by weight: 15 to 18 percent of Chinese pulsatilla root, 15 to 18 percent of ash bark, 9 to 12 percent of talc, 12 to 15 percent of wrinkled gianthyssop herb, 5 to 7 percent of hawthorn fruit, and 35 to 38 percent of pine needle meal. The feed additive is added into a piglet complete feed with the addition of 0.05 to 0.1 g/kg. The pure natural piglet immunological enhancement feed additive has the advantages that: the dosage is small, only 0.05 to 0.1 gram of the feed additive is added into one kilogram of the feed, so the feed additive generates no toxic or side effects on an animal and simultaneously cannot increase the production cost; the dosage of the feed additive is determined based on a medicament property theory of Chinese herbal medicaments, a relation between medicaments and physiological characteristics of piglets, and the medicaments are mixed reasonably; besides, the medicament formula consists of common Chinese herbal medicaments. The feed additive can effectively improve the piglet immunity and reduce the diarrhea rate so as to improve the feed intake and promote the growth; besides, the feed additive is nontoxic and provides a new way for producing safe and green pork.
Description
Technical field
The invention belongs to a kind of animal feed additive, particularly a kind of pure natural piglet immunological enhancement feed additive and application.
Background technology
The fast development of the aquaculture of two more than ten years, the food of let us is abundanter, but because the deterioration and the antibiotic abuse of breeding environment cause cultivated animals anti-adversity ability, immunocompetence, anti-stress ability to reduce.Studies show that it is one of key factor of bringing out many infectious diseases that animal body immunity (immunologic function) descends.This respect is to piglet stage (suckling pig and weanling pig) particular importance.Studies confirm that the antibody that piglet obtains is along with the prolongation of time reduces gradually from sow colostrum.Antibody if divide a word with a hyphen at the end of a line in the piglet body drops to below the certain level, will be subjected to the infection of invasive organism.Studies show that, the diarrhea rate average out to 50% that the piglet stage causes owing to immunity degradation, the serious death rate reaches 15%, thereby has had a strong impact on the economic benefit of pig industry.The problem that this piglet immunological is low is perplexing aquaculture always, becomes the technical bottleneck of herding circle for many years.So, at this moment how to allow piglet self improve immunity, be its power of resisting disease.Studies show that its survival rate height depends on the height of pigling immunity to a great extent in the piglet cultivating process.Therefore, it is very necessary improving pigling immunity.
Along with the quickening and the China joined WTO of economic globalization, the market of characteristic green feed becomes the main body of competition gradually.As the core of green feed, green feed additive is to produce nuisance free feed, and then produces one of important step of pollution-free food.Chinese herbal feed additive is little with the mode of action, the toxic and side effect of its uniqueness, noresidue, the no resistance to the action of a drug and characteristics such as pollution-free and favored.Chinese herb feed additive is to use traditional Chinese veterinarian's theory and the property theory of Chinese herbal medicine and the relation between medicine of China, the principles of formulating prescriptions according to Chinese medicine, in feed, add Chinese herbal medicine, be aided with modern scientific theory technology such as Animal nutrition and feed industry and the pure natural fodder additive made.Chinese herbal feed additive can guarantee the livestock and poultry body health, promotes to grow, and improves production performance, strengthens resistance against diseases, increases animal products output, improves the price of deed etc.Along with the needs of production scaleization, intensive culture fast development, and the negative effect of antibiotic feed additive, make and from natural resources, seek the focus that the alternative antibiotics feed addictive of safe and effective natural antibacterial medicine becomes animal husbandry research.
Therefore, it is to make China's feed industry and aquaculture go on the demand on the road of sustainable sound development that the immunity of pure natural promotes Chinese herbal feed additive to use in feed, is the wise move that improves social economy's ecological benefits.
Summary of the invention
The objective of the invention is to research and develop Chinese herb feed additive at piglet stage immunity degradation problem, according to traditional Chinese medicine theory and modern medical theory, selected multiple Chinese herbal medicine, form according to certain proportioning is refining, can effectively improve pigling immunity, reduce diarrhea rate, and then raising feed intake, promote growth, avirulence is for the pork of producing safe green provides new approach.
Feed addictive provided by the invention, the percentage by weight of its raw material components is: Chinese bulbul 15-18%, bark of ash 15-18%, talcum 9-12%, wrinkled giant hyssop 12-15%, hawthorn 5-7%, pine needle meal 35-38%.
Preparation method: raw material weighed in proportion, pulverizes, sieved (100 order), mix, make powder, packing after the quality inspection.
Use: with the addition of this feed addictive in the piglet complete feed is 0.05～0.1g/kg feed.
Principle of the present invention: this Chinese herbal feed additive is can win heat with cold, and the Chinese herbal medicine of bitter energy eliminating dampness is formed, and is used for improving immunity.The Chinese bulbul is a Ranunculaceae Pulsatilla plant in the side, have clearing heat and detoxicating, remove heat from the blood and relieve diarrhea, the effect of removing dampness and destroying parasites.The Chinese bulbul has the enhancing immunity function: the Chinese bulbul can strengthen the ability of leukocytes phagocytic staphylococcus aureus, and can strengthen the phagocytic function of reticuloendothelial system, also have tangible antidotal effect for bacteriotoxin, this can promote the body function undoubtedly, strengthens resistance against diseases.Therefore the Chinese bulbul is used for the treatment of multiple diseases such as bacillary dysentery, amoebic dysentery, pneumonia clinically.The bark of ash is the bark of the bitter manger's ash tree of Oleaceae plant, Fraxinus bungeana or pax ash.Have heat-clearing and damp-drying drug, clear liver and improve vision, the effect of antiasthmatic-antitussive.Modern pharmacology experiment shows, bark of ash effect such as have anti-inflammatory, calmness, analgesia, diuresis, antibechic, eliminate the phlegm and relieving asthma is also influential to cardiovascular system, digestive system in addition.In vitro test shows that the bark of ash has significant inhibitory effect to staphylococcus aureus, shigella flexneri, sonne bacillus, and typhoid bacillus, paratyphosum Bacterium are also had to a certain degree sensitiveness, but invalid to Escherichia coli.In vivo studies shows that the bark of ash can reduce the death rate of the chmice acute abdominal cavity infection that is caused by typhoid bacillus.Bark of ash LD
50Be 14.60gkg
-1, show that its toxicity is lower.Talcum can heat-clearing excreting dampness antidiarrheal, promoting diuresis for stranguria.Its main component is magnesium silicate, aluminium oxide, nickel oxide etc.Magnesium silicate in the talcum has absorption and astriction, for oral administrationly can protect the intestines wall, antidiarrheal and do not cause expansion; Wrinkled giant hyssop has removing dampness to restore normal functioning of the stomach antidiarrheal.It has sedation to the stomach and intestine nerve, and can expand capilary, perspiration slightly, and the gas of its fragrance can promote gastric secretion with aid digestion.Simultaneously, wrinkled giant hyssop has inhibitory action to staphylococcus aureus, Escherichia coli, shigella dysenteriae etc.; Hawthorn is the dry mature fruit of rosaceous plant large-fruited Chinese hawthorn or hawthorn, is born in mountain valley or the mountain region bushes, and the tool appetite-stimulating indigestion-relieving, the effect of long-pending, promoting blood circulation to remove blood stasis, the promoting the circulation of qi of reducing phlegm of disappearing change to stagnate.Pine needle meal is novel additive for farm animal feed, contained nutritive value is higher, with alfalfa meal, green hay powder and Chinese scholartree leaf powder ratio, the content of the dry of pine needle meal, crude fat, NFE all is the highest, wherein contained aliphatic acid has unsaturation in the crude fat, can effectively improve the quality of meat.Not only protein content is higher in the pine needle meal, and the amino acid in the protein is formed also comparatively comprehensive, contain 17 seed amino acids altogether, comprising necessary 8 seed amino acids of animal, to promoting that growing, strengthen premunition and raising reproductive function etc. all has obvious facilitation.
In this Chinese herbal feed additive, the Chinese bulbul is clearing heat and detoxicating, the clear large intestine of anti-inflammatory, and bark of ash clearing liver, is closed and is used it with cool blood through damp and hot, can be clearing heat and detoxicating, remove heat from the blood and relieve diarrhea.Be aided with fragrant and sweet medicines such as wrinkled giant hyssop, hawthorn again, the medicine-Chinese bulbul that has effectively neutralized big bitter Great Cold, the bark of ash, thereby improved the piglet palatability, solved the problem of traditional Chinese medicine " earnestly ".
The good effect that the present invention has:
The present invention compares with Chinese herb feed additive with other chemical addition agents has remarkable advantages:
1. consumption is little, only adds 0.05g/kg～0.1g/kg in feed, can not produce toxic and side effect to animal itself, also can not increase production cost simultaneously;
The dosage of each Chinese medicine of Chinese herbal feed additive 2. of the present invention is to determine that according to the property theory of Chinese herbal medicine and the relation between medicine and piglet physilogical characteristics compatibility of drugs is reasonable; And medicament composing prescription is Chinese herbal medicine commonly used.
3. can effectively improve pigling immunity, reduce diarrhea rate, and then improve feed intake, promote growth, avirulence is for the pork of producing safe green provides new approach.
The specific embodiment:
Embodiment 1:
Feed addictive raw material components percentage by weight is: the Chinese bulbul 15%, the bark of ash 17%, talcum 10%, wrinkled giant hyssop 15%, hawthorn 6%, pine needle meal 37%.
The preparation method: raw material is weighed by weight proportion, pulverize then, sieve (100 order), mixing are made powder, packing after the quality inspection.
Use: the addition of this feed addictive in the piglet complete feed is 0.05～0.1g/kg feed.
Storage practice: this feed addictive powder should be deposited in aeration-drying place.3 months summers of shelf-life, spring, autumn, 6 months winters.
Embodiment 2:
Feed addictive raw material components percentage by weight is: the Chinese bulbul 16%, the bark of ash 18%, talcum 11%, wrinkled giant hyssop 14%, hawthorn 5%, pine needle meal 36%.
Preparation method's and methods for using them is with embodiment 1.
Embodiment 3:
Feed addictive raw material components percentage by weight is: the Chinese bulbul 18%, the bark of ash 15%, talcum 12%, wrinkled giant hyssop 12%, hawthorn 7%, pine needle meal 36%.
Preparation method's and methods for using them is with embodiment 1.
Embodiment 4:
Feed addictive raw material components percentage by weight is: the Chinese bulbul 16%, the bark of ash 16%, talcum 9%, wrinkled giant hyssop 14%, hawthorn 7%, pine needle meal 38%.
Preparation method's and methods for using them is with embodiment 1.
Show through feeding experiment and clinical practice:
This experiment lasts 3 months, with the immune performance of each treated animal, and production performance, diarrhea rate is an index, evaluates the result of use of Chinese herbal feed additive of the present invention; And animal and microbiological Test by experiment, evaluate the security of Chinese herbal feed additive of the present invention.
One, the selection that breeds experimental animals
The hybridization piglet that grows up of 144 health of this experimental selection 28 ± 1 ages in days, first starting weight 6.54 ± 0.25kg.
Two, the screening of Chinese herbal feed additive raw material and prerun
Chinese herbal medicine weigh in proportion, pulverize, sieve (100 order).Mix according to proportioning, make powder.On the basis of measuring immune performance and production performance, carry out the record and the analysis of each parameter, determine best rational formula.
Three, experimental design and grouping
Experimental animal feeding is in same house.Piglet is divided into three groups at random, and (learn check by statistics, each organizes the initial method of double differences different not remarkable (P＞0.05), establishes 6 repetitions for every group, and each repeats 8 pigs.First group is control group, and second group is 1 group of test, and the 3rd group is 2 groups of tests (dividing according to different Chinese herbal feed additive prescriptions).Measure immunoglobulin content, diarrhea rate and production performance index after the off-test.21 days experimental periods.
Four, basal diet and and Chinese herbal feed additive composition
This experimental basis daily ration is based on corn-dregs of beans type.Test 1 group and in piglet diet, add 0.05g/kg Chinese herbal feed additive (prescription is for shown in the embodiment 1: the Chinese bulbul 15%, the bark of ash 17%, talcum 10%, wrinkled giant hyssop 15%, hawthorn 6%, pine needle meal 37%).Test 2 groups and in basal diet, add 0.05g/kg Chinese herbal feed additive (prescription is for shown in the embodiment 2: the Chinese bulbul 16%, the bark of ash 18%, talcum 11%, wrinkled giant hyssop 14%, hawthorn 5%, pine needle meal 36%).
Five, feeding effect
Table 1 Chinese herbal feed additive is to the influence of weanling pig immune performance
Annotate: compare with control group,
*P＜0.05, significant difference;
*P＜0.01, difference are extremely remarkable.In this experiment, test 1 group of immunoglobulin M content utmost point with 2 groups of tests and be higher than control group (P＜0.01) significantly, immunoglobulin G content is higher than control group (P＜0.05) significantly.Illustrate that two kinds of Chinese herbal feed additives have the effect that improves pigling immunity.
Chinese herbal feed additive can reduce diarrhea rate significantly.In this experiment, test 1 group and test and effectively reduce grice diarrhoea for 2 groups, with control group compare diarrhea rate difference extremely significantly (P＜0.01).
Table 2 Chinese herbal feed additive influences situation (21 days experimental periods) to the weanling pig production performance
Table 2 Chinese herbal feed additive influences situation (21 days experimental periods) to the weanling pig production performance
Annotate: compare with control group,
*P＜0.05, significant difference;
*P＜0.01, difference are extremely remarkable.
Compare with control group, test the production performance that 2 groups of 1 group and tests can improve behind the weaned piglet 21 days significantly.Can make behind the weaned piglet 21 days average daily gain improve 14.58% and 13.48% respectively, with control group significant difference (P＜0.05).The also corresponding raising of daily ingestion amount, but compare difference not significantly (P＞0.05) with control group.In addition, test 1 group and test and reduced the back 21 days feedstuff-meat ratio that weans for 2 groups, and all reached the significance degree on the statistics (P＜0.05) with the difference of control group.
Six, safety testing result
Toxicity test: carry out clinical testing with karber's method, the result of rat oral shows, the median lethal dose (LD of this Chinese herbal feed additive
50) be 17.640g/kg, belong to the avirulence material, pair cell is harmless.
Microbiological Test: show that through in vitro test Chinese herbal feed additive of the present invention can be killed harmful intestinal tract flora-Escherichia coli, staphylococcus aureus, and profitable strain-bacillus is not had effect.
The present invention shows by small-scale feeding experiment result, can improve the weanling pig weightening finish more than 13%.The as fired basis instinct of this achievement among a small circle guarantees that plant increases by 10% economic benefit, considers that from the angle of producing green pork industrialization the social benefit of this project and ecological benefits are significant.
The present invention can drive the development of China's feed industry, adjusts the antibiotic situation of the long-term use of China's additive industry, can widen China green feed additive market.
Claims (2)
1. a pure natural piglet immunological enhancement feed additive is characterized in that the percentage by weight of raw material components is: Chinese bulbul 15-18%, bark of ash 15-18%, talcum 9-12%, wrinkled giant hyssop 12-15%, hawthorn 5-7%, pine needle meal 35-38%.
2. application as above-mentioned pure natural piglet immunological enhancement feed additive, it is characterized in that: feed addictive is added in the piglet complete feed, and addition is 0.05～0.1g/kg feed.
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| CN2009102203777A CN101715893B (en) | 2009-12-04 | 2009-12-04 | Pure natural piglet immunological enhancement feed additive and application thereof |
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| CN2009102203777A CN101715893B (en) | 2009-12-04 | 2009-12-04 | Pure natural piglet immunological enhancement feed additive and application thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102771661A (en) * | 2012-06-30 | 2012-11-14 | 安徽金源农牧科技有限公司 | Pig feed capable of improving disease resistance of pigs |
| CN103599516A (en) * | 2013-11-25 | 2014-02-26 | 刘和辉 | Traditional Chinese medicine for preventing diarrhea of dairy cows and preparation method thereof |
| CN104069180A (en) * | 2013-03-27 | 2014-10-01 | 四川德润通生物科技有限公司 | Method for preparing ash bark and poplar flower compounded effervescent granules |
| CN108142687A (en) * | 2017-12-06 | 2018-06-12 | 双胞胎（集团）股份有限公司 | A kind of pig feed additive for improving feed intake and immunity |
| CN109452466A (en) * | 2018-11-20 | 2019-03-12 | 湖南诺泽生物科技有限公司 | A kind of application of composition of plant extracts in feed addictive |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1286999A (en) * | 1999-09-03 | 2001-03-14 | 周来云 | Veterinary medicine |
| KR100463804B1 (en) * | 2002-10-02 | 2004-12-29 | 이상모 | Supplement Fodder for Pet and Method For Making thereof |
| CN101336646A (en) * | 2008-05-06 | 2009-01-07 | 上海拜纳环保科技有限公司 | Natural environmental protection type dynamic sterilizing agent and preparation method thereof |
| CN101406246B (en) * | 2008-11-25 | 2011-01-26 | 福州康诺生态农业技术服务有限公司 | Chinese herbal medicine feed additive for broiler chickens as well as preparation and use thereof |
| CN101524117B (en) * | 2009-04-21 | 2011-11-23 | 陆晓巍 | Plant medicine granule serving as feed additive for preventing and treating poultry and livestock diseases and preparation thereof |
-
2009
- 2009-12-04 CN CN2009102203777A patent/CN101715893B/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102771661A (en) * | 2012-06-30 | 2012-11-14 | 安徽金源农牧科技有限公司 | Pig feed capable of improving disease resistance of pigs |
| CN104069180A (en) * | 2013-03-27 | 2014-10-01 | 四川德润通生物科技有限公司 | Method for preparing ash bark and poplar flower compounded effervescent granules |
| CN104069180B (en) * | 2013-03-27 | 2016-09-07 | 四川德润通生物科技有限公司 | The preparation method of compound bark of ash poplar flower effervescent granules |
| CN103599516A (en) * | 2013-11-25 | 2014-02-26 | 刘和辉 | Traditional Chinese medicine for preventing diarrhea of dairy cows and preparation method thereof |
| CN103599516B (en) * | 2013-11-25 | 2016-05-04 | 刘和辉 | A kind of Chinese medicine of preventing and treating milk cow diarrhoea and preparation method thereof |
| CN108142687A (en) * | 2017-12-06 | 2018-06-12 | 双胞胎（集团）股份有限公司 | A kind of pig feed additive for improving feed intake and immunity |
| CN109452466A (en) * | 2018-11-20 | 2019-03-12 | 湖南诺泽生物科技有限公司 | A kind of application of composition of plant extracts in feed addictive |
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| Publication number | Publication date |
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| CN101715893B (en) | 2012-08-22 |
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