CN100527986C - Compound feedstuff additive superfines of Chinese traditional medicine, and preparation method - Google Patents
Compound feedstuff additive superfines of Chinese traditional medicine, and preparation method Download PDFInfo
- Publication number
- CN100527986C CN100527986C CNB2006101250071A CN200610125007A CN100527986C CN 100527986 C CN100527986 C CN 100527986C CN B2006101250071 A CNB2006101250071 A CN B2006101250071A CN 200610125007 A CN200610125007 A CN 200610125007A CN 100527986 C CN100527986 C CN 100527986C
- Authority
- CN
- China
- Prior art keywords
- wilsonii
- hawthorn
- medicine material
- red sage
- sage root
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A Chinese-medicinal forage additive in the form of superfine powder for the delactated piglet is prepared from astragalus root, acanthopanax bark, pilose asiabell root, haw, red sage root, and oligochitose. Its preparing process is also disclosed.
Description
Technical field
The invention belongs to the animal feed additive technical field, more specifically relate to a kind of Chinese medicine compound prescription ultra micro powder feed additive that is used for weanling pig, also relate to the preparation method of this feed addictive simultaneously.
Background technology
For the productivity and the reduction feeding cost that improve sow, the modern intensive pig farm advanceed to for 2～4 ages in week with the weaned piglet age in days.Owing to leave the stimulation of factors such as sow and source of nutrition sudden change and other stressor ahead of time, early weaning easily causes the decline of piglet immunity of organisms, intestinal microecology imbalance, gastrointestinal tract mucous pathology, diet nutrient element can not normal stool and absorption, cause that simultaneously a series of variation takes place for blood, endocrine and nervous system etc., thereby cause grice diarrhoea, malnutrition, growth retardation, severe patient causes death.According to investigations, China's diarrhea of weaned piglets rate is up to 50%～60%, and the death rate is 15%～20%, estimates that the annual economic loss number that causes thus is in hundred million yuan.This shows that in modern large scale of pig farm was produced, diarrhoea had become and causes piglet growth to be obstructed and the one of the main reasons of high mortality, has seriously hindered the sound development of pig industry.
At present, people generally prevent and treat or alleviating diarrhoea by add antibiotic, hormone or chemical synthetic drug in animal and fowl fodder.But the long-term use of these materials causes that pathogenic microorganism develops immunity to drugs, hazard residue, animal immunizing power in livestock products and the environment descend and a series of problems such as product quality deterioration, and human health in serious threat.Therefore, many countries by legislation, are forbidden increasing antibiotic kind one after another.China is the big country of livestock products production and outlet, also is to rely on one of the most serious country of antibiotic in the world, and the main cause that calendar year 2001 China's livestock products outlet is obstructed is exactly an antibiotic residue.Seek safety, noresidue, green feed additive substitutes antibiotic efficiently, will be the requirement that ensures sustainable development of animal husbandry.
Chinese medicine is the quintessence of Chinese culture of China, has special advantages.But used Chinese herbal feed additive mostly is traditional powder at present, has problems such as DeGrain, addition is big, palatability is poor, processing technology is backward, quality control level is low.Utilizing advanced superfine communication technique, on the basis of traditional classical prescription, after the clinical symptoms screening and being improved, develop natural drug ultrafine preparation for animals, is the revolution to original Chinese medicine preparation development.Such preparation is compared with traditional Chinese medicine powder, has characteristics such as the active ingredient rate of release is fast, bioavailability is high, clinical application effect is remarkable, unit kg body weight consumption is few.Utilize existing advanced technology, carry out Chinese herbal feed additive research energetically, not only can solve the antibiotic residue problem of long-term puzzlement animal husbandry development, boost productivity, reduce the pollution of environment, develop green animal husbandry, satisfy the people's food security demand; And the gap that can dwindle China's animal husbandry and developed country, strengthen the competitiveness of China's livestock products in the international market, reduce the impact of accession to WTO to China's animal husbandry, have important economic implications and social benefit.
Summary of the invention
The object of the present invention is to provide a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive, prescription is reasonable, and active ingredient discharges fully, and addition is little, and onset is rapid, and is effective, prevented and treated grice diarrhoea effectively, improved piglet growth performance significantly.
Another object of the present invention has been to provide a kind of method for preparing weanling pig Chinese medicine compound prescription ultra micro powder feed additive, and is easy to implement the method, easy and simple to handle, applicable to large-scale production.
In order to realize above-mentioned task, the present invention adopts following technical measures:
A kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive, formulated by a certain percentage by the Radix Astragali, wilsonii, Radix Codonopsis, hawthorn, the red sage root and chitosan oligosaccharide, this additive is made up of the medicine material of following mass percent:
Medicine material mass percent (%)
The Radix Astragali 20～30
Wilsonii 20～30
Hawthorn 15～25
Radix Codonopsis 5～15
The red sage root 5～15
Chitosan oligosaccharide 5～15
Its preferred proportion is:
Medicine material mass percent (%)
The Radix Astragali 22～26
Wilsonii 23～27
Hawthorn 18～20
Radix Codonopsis 8～10
The red sage root 7～12
Chitosan oligosaccharide 10～12
Utilize effects such as its tranquilizing and allaying excitement, invigorating the spleen tonifying Qi, nourishing and strengthening vital, promoting blood circulation and food digesting stomach fortifying, improve piglet immunologic function, improve body anti-oxidation function and intestinal microecology balance, reduce the generation of diseases such as grice diarrhoea, thereby improve its growth performance.
A kind of method for preparing weanling pig Chinese medicine compound prescription ultra micro powder feed additive the steps include: at first with the segment (3-5cm) respectively of the Radix Astragali, wilsonii, Radix Codonopsis, hawthorn and the red sage root; Secondly the Radix Astragali after the segment, wilsonii, Radix Codonopsis, hawthorn and the red sage root are pulverized respectively in (145-155 order); The 3rd is to get certain proportion of astragalus, wilsonii, Radix Codonopsis, hawthorn, the red sage root and chitosan oligosaccharide pulvis to mix, and just obtains a kind of mixture; The 4th is further said mixture to be made ultramicro grinding to handle, and making average grain diameter is 30 μ m, just obtains a kind of feed addictive, and sealing is preserved after the packing.
The present invention compared with prior art has the following advantages and effect: Chinese herb compound ultra micro powder can significantly improve the immunologic function of early-weaned piglets from histoorgan, cell and molecular level; Can significantly improve anti-oxidation function, adaptability and the tolerance of early-weaned piglets; Can significantly improve the intestinal microecology of early-weaned piglets, effectively prevent and treat grice diarrhoea; Can significantly improve the digestion and absorption function of early-weaned piglets by regulating approach such as body serum biochemistry parameter and pH, thereby significantly improve its growth performance; Can significantly reduce early weaning stress be to the destruction of piglet alimentary canal shape 26S Proteasome Structure and Function.The present invention fills a prescription rationally, active ingredient discharges fully, addition is little, onset is rapid, effect is certain, have no side effect, and method is easy to implement, applicable to large-scale production.
The specific embodiment
A kind of its prescription of weanling pig Chinese medicine compound prescription ultra micro powder feed additive following (mass percent %):
| Medicine material | Example 1 | Example 2 | Example 3 | Example 4 | Example 5 | Example 6 | Example 7 | Example 8 |
| The Radix Astragali | 20 | 25 | 28 | 30 | 24 | 25 | 22 | 23 |
| Wilsonii | 30 | 20 | 27 | 20 | 26 | 25 | 28 | 24 |
| Hawthorn | 20 | 25 | 15 | 18 | 22 | 20 | 16 | 19 |
| Radix Codonopsis | 12 | 9 | 8 | 10 | 5 | 10 | 14 | 15 |
| The red sage root | 13 | 6 | 10 | 15 | 9 | 10 | 12 | 10 |
| Chitosan oligosaccharide | 5 | 15 | 12 | 7 | 14 | 10 | 8 | 9 |
External pharmacological action screening: filtering out the stronger Chinese herbal medicine of a few flavor effects from existing anti-stress medicine is research object, measures its external inhibitory action to a few boar pathogenic bacteria; Adopt the external generation hydroxy radical of ascorbic acid system method, measure the effect that it removes hydroxy radical; Utilize cell culture technology simultaneously, measure its influence weanling pig PBLC activity.
The preparation of Chinese medicine compound prescription ultra micro powder feed additive: overall merit respectively is subjected to the effects such as external antibacterial, anti-oxidant and immune enhancing of reagent thing, filtering out the obvious results Radix Astragali, wilsonii, Radix Codonopsis, hawthorn, the red sage root and chitosan oligosaccharide is the component medicine, and it is carried out scientific composition.A kind of preparation process of Chinese medicine compound prescription ultra micro powder feed additive is: at first with the segment (3-5cm) respectively of the Radix Astragali, wilsonii, Radix Codonopsis, hawthorn and the red sage root; Next is the Radix Astragali after the segment, wilsonii, Radix Codonopsis, hawthorn and the red sage root to be made 145 or 150 or 155 orders respectively pulverize; The 3rd is to get certain proportion of astragalus, wilsonii, Radix Codonopsis, hawthorn, the red sage root and chitosan oligosaccharide pulvis fully to mix, and just obtains a kind of mixture; The 4th is said mixture to be done ultramicro grinding handle, and making average grain diameter is 30 μ m, just obtains a kind of feed addictive, and sealing is preserved after the packing.Measure the content of main active such as its polysaccharide, flavones, organic acid, amino acid and alkaloid simultaneously, as one of quality control index.
Feeding experiment: the three way cross piglet of selecting the wean of 21 ages in days for use, be divided into test group and control group, the test group daily ration adds 0.2% Chinese medicine compound prescription ultra micro powder, the positive controls daily ration adds 0.02% colistin, and with basal diet as negative control, measure piglet growth performance and diarrhoea index variation respectively at adding back the 7th, 14,21 and 28d, and the variation of antibody titer such as the relevant serum biochemistry parameter of monitoring piglet, anti-oxidation function, PBLC proliferation activity and IgG, IgM and cytokine levels.
Slaughter experiment: animal used as test and divide into groups the same, butcher respectively at adding back the 7th, 14 and 28d, measure bacterial species and content, pH value, main digestive organs and the microstructural variation of immune organ index, anti-oxidation function and alimentary canal in the intestine of young pigs content.
Claims (10)
1, a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive, make by the medicine material of following mass percent:
Medicine material %
The Radix Astragali 20～30,
Wilsonii 20～30,
Hawthorn 15～25,
Radix Codonopsis 5～15,
The red sage root 5～15,
Chitosan oligosaccharide 5～15.
2, a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive according to claim 1 is characterized in that it is made by the medicine material of following mass percent:
Medicine material %
The Radix Astragali 22～26,
Wilsonii 23～27,
Hawthorn 18～20,
Radix Codonopsis 8～10,
The red sage root 7～12,
Chitosan oligosaccharide 10～12.
3, a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive according to claim 1 is characterized in that it is made by the medicine material of following mass percent:
Medicine material %
The Radix Astragali 25,
Wilsonii 25,
Hawthorn 20,
Radix Codonopsis 10,
The red sage root 10,
Chitosan oligosaccharide 10.
4, a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive according to claim 1 is characterized in that it is made by the medicine material of following mass percent:
Medicine material %
The Radix Astragali 20,
Wilsonii 30,
Hawthorn 20,
Radix Codonopsis 12,
The red sage root 13,
Chitosan oligosaccharide 5.
5, a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive according to claim 1 is characterized in that it is made by the medicine material of following mass percent:
Medicine material %
The Radix Astragali 25,
Wilsonii 20,
Hawthorn 25,
Radix Codonopsis 9,
The red sage root 6,
Chitosan oligosaccharide 15.
6, a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive according to claim 1 is characterized in that it is made by the medicine material of following mass percent:
Medicine material %
The Radix Astragali 28,
Wilsonii 27,
Hawthorn 15,
Radix Codonopsis 8,
The red sage root 10,
Chitosan oligosaccharide 12.
7, a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive according to claim 1 is characterized in that it is made by the medicine material of following mass percent:
Medicine material %
The Radix Astragali 30,
Wilsonii 20,
Hawthorn 18,
Radix Codonopsis 10,
The red sage root 15,
Chitosan oligosaccharide 7.
8, a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive according to claim 1 is characterized in that it is made by the medicine material of following mass percent:
Medicine material %
The Radix Astragali 24,
Wilsonii 26,
Hawthorn 22,
Radix Codonopsis 5,
The red sage root 9,
Chitosan oligosaccharide 14.
9, a kind of weanling pig Chinese medicine compound prescription ultra micro powder feed additive according to claim 1 is characterized in that it is made by the medicine material of following mass percent:
Medicine material %
The Radix Astragali 25,
Wilsonii 25,
Hawthorn 20,
Radix Codonopsis 10,
The red sage root 10,
Chitosan oligosaccharide 10.
10, a kind of preparation method who is used to realize the weanling pig Chinese medicine compound prescription ultra micro powder feed additive of claim 1 comprises the following steps:
A, with the Radix Astragali, wilsonii, Radix Codonopsis, hawthorn and red sage root segment 3-5cm respectively;
B, the Radix Astragali with after the segment, wilsonii, Radix Codonopsis, hawthorn and the red sage root are made the 145-155 order respectively and are pulverized;
C, get certain proportion of astragalus, wilsonii, Radix Codonopsis, hawthorn, the red sage root and chitosan oligosaccharide pulvis and mix;
D, said mixture is done ultramicro grinding, making average grain diameter is 30 μ m, and sealing is preserved after the packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101250071A CN100527986C (en) | 2006-11-10 | 2006-11-10 | Compound feedstuff additive superfines of Chinese traditional medicine, and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101250071A CN100527986C (en) | 2006-11-10 | 2006-11-10 | Compound feedstuff additive superfines of Chinese traditional medicine, and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1957742A CN1957742A (en) | 2007-05-09 |
| CN100527986C true CN100527986C (en) | 2009-08-19 |
Family
ID=38069714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006101250071A Expired - Fee Related CN100527986C (en) | 2006-11-10 | 2006-11-10 | Compound feedstuff additive superfines of Chinese traditional medicine, and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100527986C (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101703171B (en) * | 2009-11-24 | 2011-09-21 | 沈阳农业大学 | Natural vegetal anti-weaning stress feed additive and application thereof |
| CN102178122B (en) * | 2011-06-15 | 2013-04-24 | 山西省农业科学院畜牧兽医研究所 | Compound feed additive for improving pork quality |
| CN102178121B (en) * | 2011-06-15 | 2013-01-02 | 山西省农业科学院畜牧兽医研究所 | Chinese herbal medicinal superfine powder feed additive for producing high-quality pork |
| CN102512520B (en) * | 2011-11-28 | 2013-08-21 | 河南省康星药业股份有限公司 | Normal-temperature preparation method for ultrafine powder hawthorn |
| CN103283959A (en) * | 2013-01-29 | 2013-09-11 | 广州格拉姆生物科技有限公司 | Chinese herbal ultra-fine powder feed additive and its application in culture |
| CN104161187B (en) * | 2013-08-30 | 2016-08-10 | 郑州后羿制药有限公司 | A kind of poultry Chinese herbal feed additive, preparation method and application |
| CN104171500A (en) * | 2014-07-02 | 2014-12-03 | 中泰和（北京）科技发展有限公司 | Sow feed additive capable of improving immunity of piglets and using method thereof |
| CN105146099A (en) * | 2015-10-29 | 2015-12-16 | 崔永进 | Poultry feed additive for replacing antibiotics and promoting growth |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1142952A (en) * | 1994-12-17 | 1997-02-19 | 李高寅 | Glossy ganoderma oral liquor and its preparing method |
| CN1483341A (en) * | 2002-09-19 | 2004-03-24 | 田洪沛 | Natural nutrient for egg-laying poultry and use method thereof |
| CN1608487A (en) * | 2003-10-23 | 2005-04-27 | 济南海得贝海洋生物工程有限公司 | Feed additive containing chitin oligose and its prepn and use |
| CN1748550A (en) * | 2004-09-14 | 2006-03-22 | 重庆市畜牧科学研究院 | Multifunctional new feed additive of Chinese herbal medicine for pig |
-
2006
- 2006-11-10 CN CNB2006101250071A patent/CN100527986C/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1142952A (en) * | 1994-12-17 | 1997-02-19 | 李高寅 | Glossy ganoderma oral liquor and its preparing method |
| CN1483341A (en) * | 2002-09-19 | 2004-03-24 | 田洪沛 | Natural nutrient for egg-laying poultry and use method thereof |
| CN1608487A (en) * | 2003-10-23 | 2005-04-27 | 济南海得贝海洋生物工程有限公司 | Feed additive containing chitin oligose and its prepn and use |
| CN1748550A (en) * | 2004-09-14 | 2006-03-22 | 重庆市畜牧科学研究院 | Multifunctional new feed additive of Chinese herbal medicine for pig |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1957742A (en) | 2007-05-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102217713B (en) | Novel efficient and natural attractant | |
| CN100527986C (en) | Compound feedstuff additive superfines of Chinese traditional medicine, and preparation method | |
| CN103125779A (en) | Biological Chinese herbal feed additive for broiler chicken and preparation method thereof | |
| CN104186948A (en) | Total-effect health concentrated feed for pigs | |
| CN106360040B (en) | Composite Chinese herbal medicine probiotic feed additive for enhancing growth performance and immune function of broiler chickens | |
| CN103262961A (en) | Feed additive specially used for tilapia | |
| CN103300225A (en) | Chinese herbal medicine ultra-fine powder feed additive with antiviral and antibacterial effects, and preparation method thereof | |
| CN102872396B (en) | Complex Chinese herbal medicine preparation for treating diarrhea of piglets and preparation method thereof | |
| CN106306512A (en) | Fermented Chinese herbal medicine feed additive for treating porcine diarrhea | |
| CN103156061A (en) | Compound microbial active additive | |
| CN105394385A (en) | Traditional Chinese medicine preparation for preventing stress syndromes of weanling pigs and preparation method of traditional Chinese medicine preparation | |
| CN111820332A (en) | Chinese herbal medicine laying hen feed and preparation method thereof | |
| CN105285353B (en) | Rapid fattening feed for rabbits and feeding method thereof | |
| CN105410399A (en) | Selenium-rich pig feed as well as preparation method and application thereof | |
| CN104206787A (en) | Poultry feed additive and preparation method thereof | |
| CN103283959A (en) | Chinese herbal ultra-fine powder feed additive and its application in culture | |
| CN103918893B (en) | A kind of Chinese herbal medicine compound additive of animal feeding-stuff and application | |
| CN107348136A (en) | A kind of vegetalitas promotees feed addictive and the application of weanling pig gastro-intestinal digestion function | |
| CN104322948B (en) | A kind of Chinese herbal feed additive and the application in mixed feed thereof | |
| CN101715893B (en) | Pure natural piglet immunological enhancement feed additive and application thereof | |
| CN106615728A (en) | Preparation method of microbial preparation for calves | |
| CN106135748A (en) | A kind of fowl Chinese herbal medicine microorganism composite feed additive | |
| CN114176170B (en) | Functional feed additive and preparation method and application thereof | |
| CN109221697A (en) | Weaned piglets probiotic feed and preparation method thereof | |
| CN113317270B (en) | Feeding management method for improving production performance of ternary sows |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090819 Termination date: 20091210 |
|
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Hunan Perfect Bio-technology Co., Ltd. Assignor: Institute of Subtropical Agriculture, Chinese Academy of Sciences Contract record no.: 2010430000149 Denomination of invention: Compound feedstuff additive superfines of Chinese traditional medicine, and preparation method Granted publication date: 20090819 License type: Exclusive License Open date: 20070509 Record date: 20101117 |