CN107348136A - A kind of vegetalitas promotees feed addictive and the application of weanling pig gastro-intestinal digestion function - Google Patents

A kind of vegetalitas promotees feed addictive and the application of weanling pig gastro-intestinal digestion function Download PDF

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Publication number
CN107348136A
CN107348136A CN201710593763.5A CN201710593763A CN107348136A CN 107348136 A CN107348136 A CN 107348136A CN 201710593763 A CN201710593763 A CN 201710593763A CN 107348136 A CN107348136 A CN 107348136A
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feed addictive
weanling pig
gastro
vegetalitas
promotees
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刘显军
陈静
史苏
荣誉
陈畅
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Shenyang Agricultural University
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Shenyang Agricultural University
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/60Feeding-stuffs specially adapted for particular animals for weanlings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)

Abstract

A kind of vegetalitas promotees feed addictive and the application of weanling pig gastro-intestinal digestion function, it is characterized in that raw material components percentage by weight is hawthorn 35 ~ 45%, Divine Comedy 10 ~ 15%, radix glycyrrhizae 4 ~ 9%, Poria cocos 10 ~ 15%, dried orange peel 5 ~ 8%, the capsule of weeping forsythia 5 ~ 8%, radish seed 5 ~ 8%, malt 4 ~ 9%.Each composition is conventional plant in the natural plant feed addictive of the present invention, is a kind of green safe feed addictive.The dosage of each natural plants is to determine that compatibility of drugs is reasonable according to the relation between the property theory of natural plants and plant.Gastrointestinal Tract of Weanling Piglets digestive function can be improved using additive of the present invention, reduces diarrhea of weaned piglets rate, improves weaned piglets.

Description

A kind of vegetalitas promotees feed addictive and the application of weanling pig gastro-intestinal digestion function
Technical field
The invention belongs to a kind of animal feed additive, particularly a kind of vegetalitas promotees weanling pig gastro-intestinal digestion function Feed addictive and application.
Background technology
The wean of piglet is last link in sow production routine, and being related to can the numerous sow productivity of 1 year Play, be also related to growing for piglet.Wean be to piglet one stress.During wean, piglet intestines and stomach structure function is still Imperfection, the contact between stomach and nervous system are not completely set up also, and the nutritional ingredient in breast milk and various bioactivity The factor is broken off suddenly, causes hydrochloric acid in gastric juice insufficient, pH rises, causes a variety of proenzymes (pepsin, renin and lactase etc.) in stomach Activation reduced capability, the digestive utilization ratio of various nutrients reduces in feed.Simultaneously too high gastrointestinal pH is also pathogen (large intestine bar Bacterium, salmonella, staphylococcus, clostridium etc.) breeding provide favourable condition.In addition gastric acid secretion deficiency causes gastric emptying Accelerate, a large amount of undigested feeds pour in small intestine, have aggravated the burden of small intestine, have as a result caused piglet to digest and assimilate not Good, inflammation and have loose bowels, growth slows down.In production, 5~7d of weaned piglet is diarrhoea peak period, this and its intestines and stomach pH value and bacterium Group's changing rule is consistent.Therefore, the imperfection of gastro-intestinal digestion function is weanling pig immunity degradation, diarrhoea, grows and delay One of the main reason for slow.
For a long time, antibiotic has played huge effect as the growth promoter in pig feed in Swine Production, Antibiotic is improving pigling immunity, while improving feed conversion, also increases the drug resistance and pork Chinese medicine of harmful bacteria It is residual, influence human food's safety and health.Natural plants (Chinese herbal medicine) are the distinctive traditional Chinese medical theory in China and practice Product.The species of China's natural plants is various, acts on multiple-effect, and toxic side effect is small.Studies have shown that natural plants add as feed Agent is in the growing of animal, immunoregulation, nourishing and generating etc. has played good effect.And feature natural plants are raised The research and development of feed additives are increasingly becoming the new focus of animal feed research.
The content of the invention
It is an object of the invention to provide a kind of vegetalitas promote weanling pig gastro-intestinal digestion function feed addictive and application, The additive is directed to weanling pig gastrointestinal growth and physilogical characteristics, can improve piglet digestive functions, promotes nutriment Absorb, improve immunocompetence.So as to improve production performance.
The present invention Chinese medicine theory traditional according to China and modern medical theory, selected a variety of natural plants, are pressed Formed according to certain proportioning is refined, to realize improvement gastrointestinal function, promote piglet to digest and assimilate, so as to improve production performance.
The present invention provides a kind of pure plant anti-gastrointestinal tract stress feed addictive, the percentage by weight of its raw material components For:Hawthorn 35~45%, Divine Comedy 10~15%, radix glycyrrhizae 4~9%, Poria cocos 10~15%, dried orange peel 5~8%, the capsule of weeping forsythia 5~8%, Lay Fu 5~8%, malt 4~9%.
Raw material is weighed according to the above ratio, crushed, is sieved (100 mesh), mixing, powder is made, is dispensed after quality inspection.
The principle of the present invention:Hawthorn is the dry mature fruit of rosaceous plant large-fruited Chinese hawthorn or hawthorn, slightly warm in nature.Hawthorn contains There are the materials such as carbohydrate, protein, fat, starch, malic acid, citric acid, it is sour sweet, tool appetite-stimulating indigestion-relieving, change stagnant disperse accumulations, Huoxue San " The effect of stasis of blood, resolving sputum promoting the circulation of qi.Hawthorn contains the generation that the materials such as vitamin C, carrotene can block and reduce free radical, can increase The immunity of strong body;Divine Comedy is the fermented herbal leaven formed after the medicines such as polygonum flaccidum, sweet wormwood, almond add flour or wheat bran mixing, Acted on strengthening the spleen and stomach, promoting digestion and removing indigestion;Radix glycyrrhizae alias Herba Hedyotis cantonensis, Herba Hedyotis cantonensis root, it is dicotyledonous leguminous perennial herb, has Antibacterial, antiviral, anti-inflammatory, antiallergic action effect, its root and rhizome are used as medicine, and tool is invigorated the spleen and benefited qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, The functions such as relieving spasm to stop pain, coordinating the drug actions of a prescription;Poria cocos can invigorating the spleen, and can excreting dampness, Poria cocos has for diarrhea caused by insufficiency of the spleen dysfunction of the spleen in transportation and transformation The effect of giving consideration to both the incidental and fundamental;Dried orange peel has anti-inflammatory, antiulcer action;The capsule of weeping forsythia has broad-spectrum antibacterial action, to staphylococcus aureus, congratulates Shigella flexneri has very strong inhibitory action, has certain inhibitory action to other pathogenic bacteria, influenza virus.The capsule of weeping forsythia has solution Heat, diuresis, and the capsule of weeping forsythia can promote the formation of inflammatory barrier.In addition, the capsule of weeping forsythia has to a variety of Grain-positives and negative bacteria Inhibitory action, its concentrated decoction can suppress typhoid bacillus, paratyphosum Bacterium, Escherichia coli, shigella dysenteriae, corynebacterium diphtheriae in vitro And comma bacillus, staphylococcus, streptococcus etc..Radish seed is the mature seed of crucifer radish.Enter spleen, stomach, lung channel, Can be helped digestion de-swelling, and effect is notable, there is the title of " rush wall fall wall ".Available for stagnated for Therapeutic diet, abdominal distention, big constipation Knot, stagnant rush down dysentery.Malt has promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite.It is mainly used in dyspepsia, abdominal distention, spleen eating less.
Each composition of Chinese herb feed additive of the present invention is respectively provided with multiple functions, and acid ingredient can quickly make up in hawthorn in side Gastric acid secretion deficiency, with the common appetite-stimulating indigestion-relieving of radish seed.Divine Comedy, radix glycyrrhizae, Poria cocos, malt have invigorating the spleen, change stagnant disperse accumulations effect, sweet Grass, the capsule of weeping forsythia, dried orange peel have antimicrobial antiphlogistic effect.All medicine joints can quickly improve hydrochloric acid in gastric juice level, improve stomach and intestine pH value, strengthen stomach and intestine The activity of digestive ferment, so as to promote nutrient digestion, and then improve Production Performance of Weaning Pigs.Mountain in the present invention simultaneously Short, bristly hair or beard, radix glycyrrhizae property acid are sweet, can improve the taste of plant feed addictive, improve the palatability of piglet.Therefore Chinese herbal medicine of the present invention Additive has the effect of improving weanling pig gastro-intestinal digestion function.
Addition of the feed addictive of the present invention in weanling pig feed is 0.5g/kg~1g/kg feeds.Addition period For in after wean 4 weeks.
Each composition is conventional plant in the natural plant feed addictive of the present invention, is a kind of green safe feed Additive, Gastrointestinal Tract of Weanling Piglets digestive function can be improved, reduce diarrhea of weaned piglets rate, improve weaned piglets.
Embodiment
The present invention is further illustrated in embodiment below.
Embodiment 1:A kind of vegetalitas promotees the feed addictive of weanling pig gastro-intestinal digestion function.Its raw material components weight hundred Point ratio is:Hawthorn 40%, Divine Comedy 13%, radix glycyrrhizae 7%, Poria cocos 13%, dried orange peel 7%, the capsule of weeping forsythia 7%, radish 6%, malt 7%.
Preparation method:Raw material is weighed by weight proportion, then crushed, sieving (100 mesh), mixing, powder, quality inspection is made After dispense.
Using:Addition of the feed addictive in weanling pig feed is 0.5g/kg~1g/kg feeds.
Storage practice:The feed addictive powder should be deposited at aeration-drying.
Embodiment 2:A kind of vegetalitas promotees the feed addictive of weanling pig gastro-intestinal digestion function.Its raw material components weight hundred Point ratio is:Hawthorn 43%, Divine Comedy 12%, radix glycyrrhizae 7%, Poria cocos 12%, dried orange peel 6%, the capsule of weeping forsythia 7%, radish seed 7%, malt 6%.
Preparation method:Raw material is weighed by weight proportion, then crushed, sieving (100 mesh), mixing, powder, quality inspection is made After dispense.
Using:Addition of the feed addictive in weanling pig feed is 0.5g/kg~1g/kg feeds.
Storage practice:The feed addictive powder should be deposited at aeration-drying.
Embodiment 3:A kind of vegetalitas promotees the feed addictive of weanling pig gastro-intestinal digestion function.Its raw material components weight hundred Point ratio is:Hawthorn 44%, Divine Comedy 10%, radix glycyrrhizae 8%, Poria cocos 10%, dried orange peel 7%, the capsule of weeping forsythia 7%, radish seed 8%, malt 6%.
Preparation method:Raw material is weighed by weight proportion, then crushed, sieving (100 mesh), mixing, powder, quality inspection is made After dispense.
Using:Addition of the feed addictive in weanling pig feed is 0.5g/kg~1g/kg feeds.
Storage practice:The feed addictive powder should be deposited at aeration-drying.
The present invention combines the detection of feeding experiment and biochemical indicator, is applied to be further described:
1 materials and methods
1.1 experimental animals and packet
Selection is weaned for 28 ± 1 days, and healthy body weight homogeneous (first starting weight 7.4kg), which is grown up, hybridizes weanling pig 75, with Machine is divided into 3 groups (processing), control group, feeds basal diet.1 group is tested (to add 0.5g/kg plant feeds in basal diet to add Add agent), (plant feed addictive formula is implementation for 2 groups of experiment (1g/kg plant feed addictives are added in basal diet) Example 1).
1.2 test indexes determine
Record the diarrhoea situation of each processing daily, calculate daily gain, daily ingestion amount that experiment full period (1-28 days) respectively handles, Feedstuff-meat ratio and diarrhea rate.Each processing in 7 days, 14 days and 28 days randomly selects 5 pigs after wean simultaneously, and vena cava anterior is taken a blood sample, Serum is separated, determines total protein, urea nitrogen, TAC content in serum, measure immunoglobulin (IgM) and complement component 3 (C3) it is horizontal, determine serum alkaline phosphatase and creatine kinase activity.
2 results are with discussing
Influence of 2.1 plant feed addictives to Production Performance of Weaning Pigs
As shown in Table 1, whole experimental period, the daily gain of 2 groups of weanling pigs of 1 group of experiment and experiment, which is significantly higher than, to be compareed Group (P < 0.05) is higher than control group by 9.7% and 21.2% respectively.Plant feed addictive group improves the day of weanling pig Feed intake, wherein test 2 groups of daily ingestion amount is higher by 7.3% (P < 0.05) than control group.
The addition of plant feed addictive improves feed conversion rate (P < 0.05), 2 groups of wean of 1 group of experiment and experiment The feedstuff-meat ratio of piglet respectively lower than control group 7.0% and 10.1%, reaches the level of signifiance.The diarrhoea of plant feed addictive Rate has reduction compared with control group, and the diarrhea rate than control group piglet reduces 31% (P < 0.05), 35% (P < respectively 0.05)。
As a result illustrate, weanling pig daily ration kind addition plant feed addictive considerably improves the weightening of weanling pig And feed conversion rate, diarrhea rate is reduced, improves production performance.
Influence of the plant feed addictive of table 1 to Production Performance of Weaning Pigs
Note:Same column shoulder mark same letter person difference is not notable (P > 0.05), different alphabetical person's significant differences (P < 0.05). Following table is same.
Influence of 2.2 plant feed addictives to weanling pig albumen synthesis capability
Influence (g/L) of the plant feed addictive of table 2 to weanling pig total serum protein
Influence (mmol/L) of the plant feed addictive of table 3 to weanling pig serum urea nitrogen
Influence (King unit/100ml) of the plant feed addictive of table 4 to weanling pig alkaline phosphatase
Research shows that the important digestive organs gastrointestinal development of piglet could be close to normal level after 60 ages in days.Not Sour environment relies primarily in breast milk lactic acid caused by lactose fermentation to maintain in piglet before wean.And piglet hydrochloric acid in gastric juice point after weaning Obvious deficiency is secreted, causes pH to raise.Too high pH can cause pepsinia important in stomach to reduce, so as to cause albumen to disappear Change ability declines, and indigested feed pours in small intestine, easily causes piglet and malabsorption, inflammation and diarrhoea occurs.
Table 2, table 3 and the result of table 4 show that the albumen synthesis capability of 2 groups of weanling pigs of 1 group of experiment and experiment is significantly high In control group.14 days and 28 days after wean, total protein content is significantly high in 2 groups of weanling pig serum of 1 group of experiment and experiment In control group (P < 0.05).The alkaline phosphatase activities for testing 1 group and 2 groups of experiment is above control group (P in whole experimental period < 0.05), and urea nitrogen content is less than control group (P < 0.05).
The plant feed addictive of the present invention considerably improves the content and protein synthase-alkaline phosphorus of total protein Phytase activity, reduce the content of protein,split urea nitrogen.Illustrate the plant feed addictive of the invention of the present invention Pepsinia is promoted, body protein synthesis is accelerated, reduces the decomposition of albumen.
Influence of 2.3 plant feed addictives to weanling pig antioxygenic property
Influence (U/ml) of the plant feed addictive of table 5 to weanling pig TAC
Body produces a variety of free radicals in metabolic process, and free radical has extremely strong oxidability, can make in biomembrane Peroxidating occurs for unsaturated lipid, MDA is formed, so as to destroy intestines and stomach 26S Proteasome Structure and Function.In the defence body of body In system, TAC is the important index for weighing body antioxygenic property.
Table 5 understands that plant feed addictive improves the TAC of the body of weanling pig.At 14 days and 28 It when, experiment 1 group and experiment 2 groups of weanling pigs TAC be significantly higher than control group (P < 0.05).
Influence of 2.4 plant feed addictives to weanling pig immune performance
Influence (g/L) of the plant feed addictive of table 6 to weanling pig immunoglobulin M
Influence (g/L) of the plant feed addictive of table 7 to weanling pig Complement C_3
Immunoglobulin M (IgM) is to produce immunoglobulin at first in antigenic stimulus induction body fluid immune response, can be tied Close Complement C_3.Because it has higher valency, so being dynamical antibiont antibody, played in being defendd early stage body Important effect.
Table 6, the result of table 7 show that plant feed addictive improves the immune performance of the body of weanling pig.Weaning 7 days and 14 days afterwards, the IgM levels of 2 groups of weanling pigs of 1 group of experiment and experiment were significantly higher than control group.7 days after wean, experiment 1 The C3 levels of 2 groups of weanling pigs of group and experiment are significantly higher than control group (P < 0.05).Illustrate the plant feed addition of the present invention Agent, which has, promotes weanling pig immunity, improves the effect of weanling pig resistance against diseases.
2.5 plant feed addictives to weanling pig stress influence
Influence (U/ml) of the plant feed addictive of table 8 to weanling pig creatine kinase
The piglet of wean can usually be shown a series of bad existing due to that stress be influenceed by psychology, environment and nutrition As, such as apocleisis or food refusal, digestive function is disorderly, gastrointestinal tract environment changes, cause piglet occur diarrhoea, immunity degradation, Efficiency of feed utilization is low, or even growth retardation etc. occur so-called " early weaning piglet syndrome ", so as to have a strong impact on pig The economic benefit of industry.Creatine kinase (CK) be judge weanling pig stress important indicator.
Table 8 shows, the 7th day after wean, 14 days, 28 days, the serum creatine kinase of 2 groups of weanling pigs of 1 group of experiment and experiment Activity level is below control group, significant difference (P < 0.05), it is young to illustrate that plant feed addictive can significantly reduce wean The stress level of pig.
Above-mentioned result of the test shows that plant feed addictive of the invention promotes the digestion power of intestines and stomach, thus The synthesis piglet of protein in body, while corresponding immunity, oxidation resistance and the stress ability for improving weanling pig are improved, is added The plant feed addictive palatability of the present invention improve, collective effect improves feed intake and the weightening of weanling pig, has Improve to effect the economic benefit of pig industry.

Claims (2)

1. a kind of vegetalitas promotees the feed addictive of weanling pig gastro-intestinal digestion function, it is characterized in that:Its raw material components weight hundred Point ratio is:Hawthorn 35 ~ 45%, Divine Comedy 10 ~ 15%, radix glycyrrhizae 4 ~ 9%, Poria cocos 10 ~ 15%, dried orange peel 5 ~ 8%, the capsule of weeping forsythia 5 ~ 8%, radish seed 5 ~ 8%th, malt 4 ~ 9%;
Raw material is weighed in proportion, crushes, sieve, mixing, powder is made.
2. a kind of vegetalitas as claimed in claim 1 promotees the application of the feed addictive of weanling pig gastro-intestinal digestion function, its It is characterized in:Addition in weanling pig feed is 0.5 ~ 1g/kg feeds, addition period for wean after in 4 weeks.
CN201710593763.5A 2017-07-20 2017-07-20 A kind of vegetalitas promotees feed addictive and the application of weanling pig gastro-intestinal digestion function Pending CN107348136A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109758546A (en) * 2019-03-29 2019-05-17 刘坚 A kind of herbal composite that treating chitling gastric disorder and its processing and application
CN110583888A (en) * 2019-10-10 2019-12-20 江西中医药大学 Traditional Chinese medicine feed additive for preventing weaning emergency diarrhea of suckling pigs and preparation method thereof
CN110679768A (en) * 2019-11-26 2020-01-14 金华傲农生物科技有限公司 Feed additive for improving blood IGF-I concentration of weaned pigs and promoting growth and preparation method and application thereof
CN115518106A (en) * 2022-09-16 2022-12-27 四川恒通动物制药有限公司 A veterinary Chinese medicinal composition for protecting gastrointestinal tract, and its preparation method

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CN105688129A (en) * 2014-11-26 2016-06-22 天津必佳药业有限公司 Swine diarrhea oral liquid and making method thereof
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109758546A (en) * 2019-03-29 2019-05-17 刘坚 A kind of herbal composite that treating chitling gastric disorder and its processing and application
CN110583888A (en) * 2019-10-10 2019-12-20 江西中医药大学 Traditional Chinese medicine feed additive for preventing weaning emergency diarrhea of suckling pigs and preparation method thereof
CN110679768A (en) * 2019-11-26 2020-01-14 金华傲农生物科技有限公司 Feed additive for improving blood IGF-I concentration of weaned pigs and promoting growth and preparation method and application thereof
CN115518106A (en) * 2022-09-16 2022-12-27 四川恒通动物制药有限公司 A veterinary Chinese medicinal composition for protecting gastrointestinal tract, and its preparation method

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