CN105394385A - Traditional Chinese medicine preparation for preventing stress syndromes of weanling pigs and preparation method of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine preparation for preventing stress syndromes of weanling pigs and preparation method of traditional Chinese medicine preparation Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations for veterinary use and particularly relates to a traditional Chinese medicine preparation for preventing stress syndromes of weanling pigs and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is mainly prepared from the following raw materials in parts by weight: Chinese mugwort leaves, galangals, cassia seeds, cordate houttuynia, scutellaria baicalensis, purslane, moutan barks, jasmines, mangnolia officinalis, tangerine peels, fingered citron, selfheal, pine needle powder and medical stone flour. The traditional Chinese medicine preparation for preventing the stress syndromes of the weanling pigs, provided by the invention, has the remarkable effects of resisting bacteria and resisting viruses and can be used for remarkably improving the immunity of the weanling pigs; and the traditional Chinese medicine preparation can be used for effectively adjusting the gastrointestinal tract functions of piglets, reducing the diarrhea phenomenon of the piglets, improving the appetite of the piglets, promoting the absorption on nutrient substances, improving the daily gain and feed conversion efficiency of the weanling pigs, and effectively alleviating the stress syndromes of the weanling pigs.
Description
Technical field
The invention belongs to veterinary Chinese medicine formulation art, be specifically related to a kind ofly prevent weanling pig stress the Chinese medicine preparation and preparation method thereof of syndrome.
Background technology
At present, the pig farm of China's intensive manufacture, in order to improve the reproductive capacity of sow, reduce the propagation of epidemic disease, promotes growing of piglet, and piglet generally carries out wean process when 3-5 age in week, piglet and sow are separated during wean, the feed of piglet becomes dry feed or particulate material from full milk daily ration.Piglet after wean due to autodigestion function imperfection, immunity lower, the stress such as physiology, nutrition and environment are subject to after adding wean, so piglet normal phenomenon that diarrhoea and refusal feed occur in wean one week, the normal growth that the lighter affects piglet is grown, severe one causes piglet dead, cause huge loss to pig farm, also limit the universal of this advanced technology of early weaning piglet and application simultaneously.
In order to solve the problem, the keeper on pig farm be everlasting weanling pig diet in add the additives such as antibiotic, probiotic, oligosaccharide, enzyme preparation, organic mineral substance or excessive trace element.Above-mentioned additive effectively can suppress harmful microbe Growth and reproduction in piglet digestive, maintains piglet stomach healthy, increases the appetite of piglet, and then promotes the g and D of piglet, improves culture benefit.But Long-Time Service antibiotic easily produces drug tolerant bacteria and easily remains in swine product, and affects human health by food chain, causes larger threat to the health of the mankind.
In recent years, constantly studies have found that, some Chinese herbal medicines not only can promote growth of animals or poultry as feed addictive, suppress pathogen, all right develop immunitypty, improves the premunition of livestock and poultry, and these Chinese herbal medicines are natural plants mostly, adding in feed and can not remain in the body of piglet, more can not produce the problem of drug resistance, is the feed addictive of a kind of pure natural, nothing harm, environment-friendly type.
Zhou Xueyu has delivered the paper that one section of exercise question is " research of Chinese traditional compound medicine control diarrhea of weaned piglets effect ", described Chinese traditional compound medicine is prepared from by raw materials such as Radix Codonopsis, Poria cocos, the bighead atractylodes rhizome, Radix Glycyrrhizae and the Radixs Astragali, the experiment proved that, this Chinese traditional compound medicine can effectively reduce the diarrhoea degree of weaned piglet as feed addictive, improve digestibility and the utilization rate of nutriment, strengthen metabolism, stimulate circulation, improve the speed of growth.But above-mentioned Chinese traditional compound medicine taste is more bitter, is unfavorable for that piglet is taken food.
Chinese patent CN103340302B discloses a kind of weanling pig Chinese herbal feed additive and preparation method thereof, described Chinese herbal feed additive is the Chinese herbal medicine concentrate of 65:5:5:30 by weight ratio, medical stone powder, peony meal powder and supplementary product starch are made, the bulk drug of described Chinese herbal medicine concentrate according to parts by weight by dried immature fruit of citron orange 9-15 part, cogongrass rhizome 7-11 part, bighead atractylodes rhizome 6-10 part, Radix Glycyrrhizae 6-8 part, Radix Isatidis 8-12 part, dandelion 4-6 part, cordate houttuynia 8-12 part, honeysuckle 9-13 part, Divine Comedy 4-6 part, hawthorn 10-20 part, calcined oyster shell shell powder 5-7 part, medical stone powder 2-4 part and alum powder 10-18 part composition, the relative density of described Chinese herbal medicine concentrate is 1.10.The Chinese herbal feed additive prepared can improve growth performance and the immunity of piglet, improves the absorption function of intestinal mucosa, alleviates the irritability syndrome of weanling pig.But the calcined oyster shell shell in this Chinese herbal feed additive could use after need calcining 2h with charcoal fire under 600 DEG C of conditions, adds production cost greatly, is unfavorable for production and the popularization of this Chinese herbal feed additive.
Summary of the invention
The feed addictive of syndrome stress there is palatability difference, become to produce the high shortcoming of cost to overcome prior art prevention weanling pig.The object of the present invention is to provide and a kind ofly prevent weanling pig stress the Chinese medicine preparation and preparation method thereof of syndrome, to overcome the above problems.
The invention provides and a kind ofly prevent weanling pig stress the Chinese medicine preparation of syndrome, comprise following raw materials and parts by weight thereof:
Tarragon 10-20 part, galangal 8-16 part, cassia seed 6-10 part, cordate houttuynia 8-14 part, root of large-flowered skullcap 4-8 part, purslane 6-12 part, moutan bark 5-10 part, cape jasmine 7-14 part, bark of official magnolia 6-12 part, dried orange peel 10-16 part, Buddha's hand 4-10 part, selfheal 2-8 part, pine needle meal 10-18 part and medical stone powder 4-8 part.
Further, described prevention weanling pig the Chinese medicine preparation of syndrome stress comprise following raw materials and parts by weight thereof:
Tarragon 18 parts, galangal 14 parts, cassia seed 8 parts, cordate houttuynia 10 parts, the root of large-flowered skullcap 6 parts, purslane 8 parts, moutan bark 6 parts, cape jasmine 10 parts, the bark of official magnolia 9 parts, dried orange peel 14 parts, Buddha's hand 6 parts, selfheal 4 parts, pine needle meal 14 parts and medical stone powder 6 parts.
The pharmacological research of modern medicine finds, tarragon is a kind of medicine of anti-bacteria and anti-virus, can strengthen the resistivity to disease.Cordate houttuynia has inducing diuresis for treating strangurtia, the effect of anti-bacteria and anti-virus, cassia seed, purslane and cape jasmine have clearing heat and detoxicating, antidiarrheal dysentery, effect except intestines dirt, beneficial gas qi-restoratives, pine needle meal contains the nutriments such as abundant flavones, hormone, terpenoid, can promote the growing of livestock and poultry, strengthen premunition.Pine needle meal and tarragon, cordate houttuynia, cassia seed, purslane and cape jasmine are arranged in pairs or groups the effect using and have antiviral, antibacterial, clearing heat and detoxicating, loose blood significantly and subside a swelling, effectively can reduce the diarrhoea phenomenon of weanling pig, strengthen the immunity of weanling pig, promote the g and D of weanling pig.
Prevention weanling pig provided by the invention stress contain a large amount of Galangins, protocatechuic acid, Quercetin and Kaempferol isoreactivity composition for galangal in the Chinese medicine preparation of syndrome, to gram-positive bacteria and Gram-negative bacteria, all there is remarkable antibacterial activity, Paeonol in moutan bark is inhibited to golden yellow glucose coccus, Escherichia coli and Pseudomonas aeruginosa, medical stone is a kind of natural medicine ore, containing common element and zinc, iron, selenium and other trace elements such as potassium necessary in animal body, sodium, calcium.Medical stone and galangal and moutan bark are arranged in pairs or groups and are used, greatly can strengthen the antibacterial action of galangal and moutan bark, can effectively suppress intestines and stomach harmful microbe to grow, promote beneficial microorganism breeding, thus reach the gastrointestinal function regulating weanling pig, promote the absorption of nutriment.
Buddha's hand has effect of regulating qi-flowing for eliminating phlegm, preventing or arresting vomiting detumescence, liver soothing and speen fortifying, stomach strengthening and digestion promoting, and dried orange peel is used for lung qi and gathers around stagnant, chest diaphragm ruffian full and the taste stagnation of the circulation of vital energy, abdominal fullness and distention, n and V, poor appetite, the symptoms such as indigestion, the bark of official magnolia be used for lower gas wide in, consumer product dredge stasis etc. symptom.Buddha's hand and dried orange peel magnolia obovata conbined usage, can strengthen the digestive function of weanling pig significantly, strengthens the appetite of piglet, promotes the g and D of weanling pig.
Prevention weanling pig provided by the invention stress the Chinese medicine preparation of syndrome have clearing heat and detoxicating, stomach strengthening and digestion promoting, liver soothing and speen fortifying, anti-bacteria and anti-virus, promotion is digested and assimilated, the effects such as develop immunitypty, this Chinese medicine preparation can regulate the gastrointestinal function of piglet as feed addictive, reduce the diarrhoea phenomenon of weanling pig, improve the absorption function of the intestinal mucosa of weanling pig, promote the absorption of nutriment, it contains dried orange peel and the distinctive fragrance of pine needle meal simultaneously, the appetite of piglet can be strengthened, promote the g and D of weanling pig, can effectively prevent and alleviate the irritability syndrome of weanling pig.
In addition, present invention also offers and a kind ofly prevent weanling pig stress the preparation method of Chinese medicine preparation of syndrome, comprise the following steps:
Tarragon is pulverized by S1, crosses 50-70 order, puts into supercritical CO
2in extraction equipment, extraction 1-3h, obtains Folium Artemisiae Argyi extract;
S2 gets galangal, cassia seed, cordate houttuynia, purslane, cape jasmine, the bark of official magnolia and selfheal, adding above-mentioned medicinal material weight 6-10 times concentration is the ethanol of 70-85%, ultrasonic wave extracts 2-3 time, filter, merging filtrate, by decompression filtrate recycling ethanol, and at 60-65 DEG C, be concentrated into relative density be 1.10-1.20, obtains medicinal extract;
S3 gets the root of large-flowered skullcap and moutan bark is cleaned, and adds the root of large-flowered skullcap and moutan bark gross weight 4-8 soak by water doubly 2-3 time, filters, merging decoction liquor, and spraying dry, obtains mixed extract;
Dried orange peel and Buddha's hand are cleaned by S4, add dried orange peel and Buddha's hand gross weight 2-3 times of water heating and refluxing extraction, extract 2-3 time, filter, merging filtrate, and retain filter residue, spraying dry, obtains medicinal extract;
The filter residue that pine needle meal, medical stone powder and step S4 obtain by S5 carries out ultramicro grinding respectively, after crossing 100-200 mesh sieve, the mixed extract that the medicinal extract that the Folium Artemisiae Argyi extract obtained with step S1, step S2 obtain, step S3 obtain and the medicinal extract that step S4 obtains mix, after stirring, spraying dry, to obtain final product.
Further, supercritical CO in described step S1
2the CO of extraction equipment
2flow velocity is 35-55L/h.
Further, supercritical CO in described step S1
2the CO of extraction equipment
2flow velocity is 45-50L/h.
Further, supercritical CO in described step S1
2the pressure of extraction equipment is 15-25MPa, and temperature is 35-45 DEG C.
Further, the power of the ultrasonic wave process in described step S2 is 450-550W.
Also have, prevention weanling pig provided by the invention stress the Chinese medicine preparation of syndrome stress application in the feed addictive of syndrome preparation weanling pig, described prevention weanling pig stress syndrome Chinese medicine preparation addition based on the 0.2-0.4% of daily ration quality.
In a word, prevention weanling pig provided by the invention stress the Chinese medicine preparation of syndrome, compared with prior art has following advantage:
1) prevention weanling pig provided by the invention the Chinese medicine preparation of syndrome stress have antibacterial, antiviral effect significantly, effectively can reduce the diarrhoea phenomenon of weanling pig, strengthen the immunity of weanling pig, promote the g and D of weanling pig;
2) prevention weanling pig provided by the invention the Chinese medicine preparation of syndrome stress have abundant nutriment, the nutritional need of piglet can be met, improve function of intestinal canal, improve weanling pig daily gain and feed efficiency, effectively can alleviate the irritability syndrome of weanling pig;
3) prevention weanling pig provided by the invention stress the Chinese medicine preparation good palatability of syndrome, and production cost is low, and avoid the drug resistance and problem of environmental pollution that use antibiotic and chemical synthetic drug to produce, be a kind of green simultaneously, the Chinese medicine preparation of environmental protection.
Detailed description of the invention
Further describe the present invention below by way of specific embodiment, the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the change carried out the present invention, combination or replacement, be apparent for a person skilled in the art, and be included within the scope of the present invention.
embodiment 1,a kind ofly prevent weanling pig stress the Chinese medicine preparation of syndrome
Described prevention weanling pig the Chinese medicine preparation of syndrome stress comprise following raw materials and parts by weight thereof:
Tarragon 10 parts, galangal 8 parts, cassia seed 6 parts, cordate houttuynia 8 parts, the root of large-flowered skullcap 4 parts, purslane 6 parts, moutan bark 5 parts, cape jasmine 7 parts, the bark of official magnolia 6 parts, dried orange peel 10 parts, Buddha's hand 4 parts, selfheal 2 parts, pine needle meal 10 parts and medical stone powder 4 parts.
Preparation method:
Tarragon is pulverized by S1, crosses 50 orders, puts into supercritical CO
2in extraction equipment, extraction 1h, described CO
2flow velocity is 35L/h, and pressure is 15MPa, and temperature is 35 DEG C, obtains Folium Artemisiae Argyi extract;
S2 gets galangal, cassia seed, cordate houttuynia, purslane, cape jasmine, the bark of official magnolia and selfheal, adding above-mentioned medicinal material weight 6 times of concentration is the ethanol of 70%, ultrasonic wave extracts 2 times, the power of described ultrasonic wave process is 450W, filter, merging filtrate, by decompression filtrate recycling ethanol, and to be concentrated into relative density at 60 DEG C be 1.10, obtain medicinal extract;
S3 gets the root of large-flowered skullcap and moutan bark is cleaned, and adds the soak by water 2 times of the root of large-flowered skullcap and moutan bark gross weight 4 times, filters, and merge decoction liquor, spraying dry, obtains mixed extract;
Dried orange peel and Buddha's hand are cleaned by S4, add dried orange peel and Buddha's hand gross weight 2 times of water heating and refluxing extraction, extract 2 times, filter, merging filtrate, and retain filter residue, spraying dry, obtains medicinal extract;
The filter residue that pine needle meal, medical stone powder and step S4 obtain by S5 carries out ultramicro grinding respectively, after crossing 100 mesh sieves, the mixed extract that the medicinal extract that the Folium Artemisiae Argyi extract obtained with step S1, step S2 obtain, step S3 obtain and the medicinal extract that step S4 obtains mix, after stirring, spraying dry, to obtain final product.
embodiment 2,a kind ofly prevent weanling pig stress the Chinese medicine preparation of syndrome
Described prevention weanling pig the Chinese medicine preparation of syndrome stress comprise following component and parts by weight thereof:
Tarragon 18 parts, galangal 14 parts, cassia seed 8 parts, cordate houttuynia 10 parts, the root of large-flowered skullcap 6 parts, purslane 8 parts, moutan bark 6 parts, cape jasmine 10 parts, the bark of official magnolia 9 parts, dried orange peel 14 parts, Buddha's hand 6 parts, selfheal 4 parts, pine needle meal 14 parts and medical stone powder 6 parts.
Preparation method:
Tarragon is pulverized by S1, crosses 60 orders, puts into supercritical CO
2in extraction equipment, extraction 2h, described CO
2flow velocity is 50L/h, and pressure is 20MPa, and temperature is 40 DEG C, obtains Folium Artemisiae Argyi extract;
S2 gets galangal, cassia seed, cordate houttuynia, purslane, cape jasmine, the bark of official magnolia and selfheal, adding above-mentioned medicinal material weight 8 times of concentration is the ethanol of 75%, ultrasonic wave extracts 2 times, the power of described ultrasonic wave process is 500W, filter, merging filtrate, by decompression filtrate recycling ethanol, and to be concentrated into relative density at 62 DEG C be 1.15, obtain medicinal extract;
S3 gets the root of large-flowered skullcap and moutan bark is cleaned, and adds the soak by water 2 times of the root of large-flowered skullcap and moutan bark gross weight 6 times, filters, and merge decoction liquor, spraying dry, obtains mixed extract;
Dried orange peel and Buddha's hand are cleaned by S4, add dried orange peel and Buddha's hand gross weight 2 times of water heating and refluxing extraction, extract 2 times, filter, merging filtrate, and retain filter residue, spraying dry, obtains medicinal extract;
The filter residue that pine needle meal, medical stone powder and step S4 obtain by S5 carries out ultramicro grinding respectively, after crossing 140 mesh sieves, the mixed extract that the medicinal extract that the Folium Artemisiae Argyi extract obtained with step S1, step S2 obtain, step S3 obtain and the medicinal extract that step S4 obtains mix, after stirring, spraying dry, to obtain final product.
embodiment 3,a kind ofly prevent weanling pig stress the Chinese medicine preparation of syndrome
Described prevention weanling pig the Chinese medicine preparation of syndrome stress comprise following component and parts by weight thereof:
Tarragon 20 parts, galangal 16 parts, cassia seed 10 parts, cordate houttuynia 14 parts, the root of large-flowered skullcap 8 parts, purslane 12 parts, moutan bark 10 parts, cape jasmine 14 parts, the bark of official magnolia 12 parts, dried orange peel 16 parts, Buddha's hand 10 parts, selfheal 8 parts, pine needle meal 18 parts and medical stone powder 8 parts.
Preparation method:
Tarragon is pulverized by S1, crosses 70 orders, puts into supercritical CO
2in extraction equipment, extraction 3h, described CO
2flow velocity is 55L/h, and pressure is 25MPa, and temperature is 45 DEG C, obtains Folium Artemisiae Argyi extract;
S2 gets galangal, cassia seed, cordate houttuynia, purslane, cape jasmine, the bark of official magnolia and selfheal, adding above-mentioned medicinal material weight 10 times of concentration is the ethanol of 85%, ultrasonic wave extracts 3 times, the power of described ultrasonic wave process is 550W, filter, merging filtrate, by decompression filtrate recycling ethanol, and to be concentrated into relative density at 65 DEG C be 1.20, obtain medicinal extract;
S3 gets the root of large-flowered skullcap and moutan bark is cleaned, and adds the soak by water 3 times of the root of large-flowered skullcap and moutan bark gross weight 8 times, filters, and merge decoction liquor, spraying dry, obtains mixed extract;
Dried orange peel and Buddha's hand are cleaned by S4, add dried orange peel and Buddha's hand gross weight 3 times of water heating and refluxing extraction, extract 3 times, filter, merging filtrate, and retain filter residue, spraying dry, obtains medicinal extract;
The filter residue that pine needle meal, medical stone powder and step S4 obtain by S5 carries out ultramicro grinding respectively, after crossing 200 mesh sieves, the mixed extract that the medicinal extract that the Folium Artemisiae Argyi extract obtained with step S1, step S2 obtain, step S3 obtain and the medicinal extract that step S4 obtains mix, after stirring, spraying dry, to obtain final product.
comparative example 1,a kind ofly prevent weanling pig stress the Chinese medicine preparation of syndrome
Described prevention weanling pig the Chinese medicine preparation of syndrome stress comprise following component and parts by weight thereof:
Tarragon 18 parts, galangal 14 parts, cassia seed 8 parts, cordate houttuynia 10 parts, the root of large-flowered skullcap 6 parts, purslane 8 parts, cape jasmine 10 parts, the bark of official magnolia 9 parts, dried orange peel 14 parts, Buddha's hand 6 parts, selfheal 4 parts, pine needle meal 14 parts and medical stone powder 6 parts.
Preparation method is similar to Example 2.
comparative example 2,a kind ofly prevent weanling pig stress the Chinese medicine preparation of syndrome
Described prevention weanling pig the Chinese medicine preparation of syndrome stress comprise following component and parts by weight thereof:
Tarragon 18 parts, galangal 14 parts, cassia seed 8 parts, cordate houttuynia 10 parts, the root of large-flowered skullcap 6 parts, purslane 8 parts, moutan bark 6 parts, cape jasmine 10 parts, the bark of official magnolia 9 parts, dried orange peel 14 parts, Buddha's hand 6 parts, selfheal 4 parts and medical stone powder 6 parts.
Preparation method is similar to Example 2.
test example one,prevention weanling pig stress the Chinese medicine preparation of syndrome on the impact of piglet nutrient digestibility
1, subjects: choose the sodium selenite 40 that age in days is 22-28, average weight 6.0-6.2kg.
2, test material: the prevention weanling pig of embodiment 1, embodiment 2 and embodiment 3 preparation stress the Chinese medicine preparation of syndrome.
3, test method:
40 sodium selenites are divided into 4 groups at random, are respectively control group, embodiment 1 group, embodiment 2 groups and embodiment 3 groups, often organize 10.Then piglet is carried out wean process, and following feed of feeding,
Control group: basal diet of feeding;
Embodiment 1 group: mixed fodder of feeding, described mixed fodder is the Chinese medicine preparation adding 0.3% embodiment 1 preparation in basal diet;
Embodiment 2 groups: mixed fodder of feeding, described mixed fodder is the Chinese medicine preparation adding 0.3% embodiment 2 preparation in basal diet;
Embodiment 3 groups: mixed fodder of feeding, described mixed fodder is the Chinese medicine preparation adding 0.3% embodiment 3 preparation in basal diet;
Each group of piglet adopts high bed crack to raise, and conveniently carries out disinfection to pig house, makes its free choice feeding, drinking-water.Raise 4 weeks, during carrying out feeding experiment, within last 1 week, adopt endogenous indicator method to carry out digestion trial in test, experimental period is 7d, and wherein preliminary trial period is 3d, observes feed intake and the defecation rule of pig; Just the phase of trying is 4d, receives excrement every day 3 times, each about 100g, loads sealing plastic bag sealing, preserves in-30 DEG C of refrigerators.
3, result of the test
Result of the test is as shown in table 1.
The digestibility test data of table 1 weanling pig
| Crude protein | Calcium | Phosphorus | Dry | |
| Control group | 83.82±0.34 | 46.70±0.12 | 68.76±0.20 | 78.30±0.30 |
| Embodiment 1 group | 86.92±0.38** | 50.18±0.18** | 72.94±0.28** | 82.24±0.32** |
| Embodiment 2 groups | 88.76±0.42** | 52.34±0.22** | 74.12±0.32** | 83.56±0.38** |
| Embodiment 3 groups | 87.42±0.40** | 50.98±0.20** | 73.32±0.28** | 82.84±0.36** |
Note: compared with control group, * * P < 0.01.
As shown in Table 1, with the addition of prevention weanling pig provided by the invention stress the basal diet of Chinese medicine preparation of syndrome, compared with control group, piglet after wean is to crude protein, calcium, the digestibility of phosphorus and dry has the effect of extremely significantly (P < 0.01), illustrate that prevention weanling pig provided by the invention the Chinese medicine preparation of syndrome stress can regulate the gastrointestinal function of piglet, improve the intestinal mucosa absorption function of weanling pig, promote the absorption of nutriment, the digestive function of weanling pig can be strengthened significantly, strengthen the appetite of piglet, promote the g and D of weanling pig.
test example two,prevention weanling pig stress the Chinese medicine preparation of syndrome on the impact of weaned piglets
1, subjects: choose the sodium selenite 40 that age in days is 22-28, average weight 6.0-6.2kg.
2, test material: the prevention weanling pig of embodiment 2, comparative example 1 and comparative example 2 preparation stress the Chinese medicine preparation of syndrome.
3, test method:
40 sodium selenites are divided into 4 groups at random, are respectively control group, embodiment 2 groups, comparative example 1 group, comparative example 2 groups, often organize 10.Then piglet is carried out wean process, and following feed of feeding, basal diet is based on corn-soybean meal, and the feed of each group is as follows:
Control group: basal diet of feeding;
Embodiment 2 groups: mixed fodder of feeding, described mixed fodder is the Chinese medicine preparation adding 0.3% embodiment 2 preparation in basal diet;
Comparative example 1 group: mixed fodder of feeding, described mixed fodder is the Chinese medicine preparation adding 0.3% comparative example 1 preparation in basal diet;
Comparative example 2 groups: mixed fodder of feeding, described mixed fodder is the Chinese medicine preparation adding 0.3% comparative example 2 preparation in basal diet;
Each group of piglet adopts high bed crack to raise, and conveniently carries out disinfection to pig house, makes its free choice feeding, drinking-water.After feeding 2 weeks, carry out empty stomach weigh in the 14th day morning of experimental period to piglet, calculate weightening finish and feed-weight ratio, feed-weight ratio is the ratio of feeding feed stuff gross weight and weight gain of piglets, records the diarrhea rate often organizing piglet in experimental period every day simultaneously.
4, result of the test
Result of the test is as shown in table 2.
Table 2 prevent weanling pig stress the Chinese medicine preparation of syndrome on the impact of weaned piglets
| Control group | Embodiment 2 groups | Comparative example 1 group | Comparative example 2 groups | |
| Starting weight (kg) | 6.02±0.84 | 6.04±0.86 | 6.08±0.88 | 6.04±0.86 |
| End heavy (kg) | 8.50±0.90 | 10.14±1.02 | 9.20±0.98 | 9.42±1.00 |
| Daily ingestion amount (g/d) | 195.28±37.50 | 338.82±50.42** | 269.16±45.64* | 294.22±48.92* |
| Day increment (g/d) | 180.82±35.68 | 320.58±46.24** | 248.56±39.46* | 270.18±42.34* |
| Feed-weight ratio | 1.10±0.04 | 1.06±0.03 | 1.08±0.04 | 1.09±0.06 |
| Diarrhea rate (%) | 56% | 10% | 38% | 24% |
Note: compared with control group, * P < 0.05, * * P < 0.01.
Can be drawn by table 2, compared with control group, comparative example 1 group and comparative example 2 groups can the significantly daily ingestion amount of the increasing weanling pig of (P < 0.05) and adding weights, and embodiment 2 groups can the extremely significantly daily ingestion amount of the increasing weanling pig of (P < 0.01) and adding weight.Compared with control group, embodiment 2 groups, comparative example 1 group and comparative example 2 groups all can reduce the diarrhea rate of weanling pig significantly, especially the diarrhea rate of embodiment 2 groups is minimum, illustrate invent the prevention weanling pig that provides stress the Chinese medicine preparation of syndrome can effectively prevent and alleviate weanling pig stress syndrome.
Claims (8)
1. prevent weanling pig stress the Chinese medicine preparation of syndrome, it is characterized in that, comprise following raw materials and parts by weight thereof:
Tarragon 10-20 part, galangal 8-16 part, cassia seed 6-10 part, cordate houttuynia 8-14 part, root of large-flowered skullcap 4-8 part, purslane 6-12 part, moutan bark 5-10 part, cape jasmine 7-14 part, bark of official magnolia 6-12 part, dried orange peel 10-16 part, Buddha's hand 4-10 part, selfheal 2-8 part, pine needle meal 10-18 part and medical stone powder 4-8 part.
2. prevention weanling pig as claimed in claim 1 stress the Chinese medicine preparation of syndrome, it is characterized in that, comprises following raw materials and parts by weight thereof:
Tarragon 18 parts, galangal 14 parts, cassia seed 8 parts, cordate houttuynia 10 parts, the root of large-flowered skullcap 6 parts, purslane 8 parts, moutan bark 6 parts, cape jasmine 10 parts, the bark of official magnolia 9 parts, dried orange peel 14 parts, Buddha's hand 6 parts, selfheal 4 parts, pine needle meal 14 parts and medical stone powder 6 parts.
3. prevention weanling pig as claimed in claim 1 or 2 stress the preparation method of Chinese medicine preparation of syndrome, it is characterized in that, comprises the following steps:
Tarragon is pulverized by S1, crosses 50-70 order, puts into supercritical CO
2in extraction equipment, extraction 1-3h, obtains Folium Artemisiae Argyi extract;
S2 gets galangal, cassia seed, cordate houttuynia, purslane, cape jasmine, the bark of official magnolia and selfheal, adding above-mentioned medicinal material weight 6-10 times concentration is the ethanol of 70-85%, ultrasonic wave extracts 2-3 time, filter, merging filtrate, by decompression filtrate recycling ethanol, and at 60-65 DEG C, be concentrated into relative density be 1.10-1.20, obtains medicinal extract;
S3 gets the root of large-flowered skullcap and moutan bark is cleaned, and adds the root of large-flowered skullcap and moutan bark gross weight 4-8 soak by water doubly 2-3 time, filters, merging decoction liquor, and spraying dry, obtains mixed extract;
Dried orange peel and Buddha's hand are cleaned by S4, add dried orange peel and Buddha's hand gross weight 2-3 times of water heating and refluxing extraction, extract 2-3 time, filter, merging filtrate, and retain filter residue, spraying dry, obtains medicinal extract;
The filter residue that pine needle meal, medical stone powder and step S4 obtain by S5 carries out ultramicro grinding respectively, after crossing 100-200 mesh sieve, the mixed extract that the medicinal extract that the Folium Artemisiae Argyi extract obtained with step S1, step S2 obtain, step S3 obtain and the medicinal extract that step S4 obtains mix, after stirring, spraying dry, to obtain final product.
4. prevention weanling pig as claimed in claim 3 stress the preparation method of Chinese medicine preparation of syndrome, it is characterized in that, supercritical CO in described step S1
2the CO of extraction equipment
2flow velocity is 35-55L/h.
5. prevention weanling pig as claimed in claim 4 stress the preparation method of Chinese medicine preparation of syndrome, it is characterized in that, supercritical CO in described step S1
2the CO of extraction equipment
2flow velocity is 45-50L/h.
6. prevention weanling pig as claimed in claim 3 stress the preparation method of Chinese medicine preparation of syndrome, it is characterized in that, supercritical CO in described step S1
2the pressure of extraction equipment is 15-25MPa, and temperature is 35-45 DEG C.
7. prevention weanling pig as claimed in claim 3 stress the preparation method of Chinese medicine preparation of syndrome, it is characterized in that,
The power of the ultrasonic wave process in described step S2 is 450-550W.
8. prevention weanling pig as claimed in claim 1 or 2 stress the Chinese medicine preparation of syndrome stress application in the feed addictive of syndrome preparation weanling pig.
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