CN101961391A - Traditional Chinese medicine composition for preventing and controlling grass carp disease - Google Patents
Traditional Chinese medicine composition for preventing and controlling grass carp disease Download PDFInfo
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- CN101961391A CN101961391A CN201010207299XA CN201010207299A CN101961391A CN 101961391 A CN101961391 A CN 101961391A CN 201010207299X A CN201010207299X A CN 201010207299XA CN 201010207299 A CN201010207299 A CN 201010207299A CN 101961391 A CN101961391 A CN 101961391A
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Abstract
The invention relates to a traditional Chinese medicine composition for preventing and controlling grass carp diseases, which is characterized by being prepared by mixing components in parts by weight together. The traditional Chinese medicine composition is prepared by the following steps of: firstly weighing 100-300 parts of milk veteh, 200-400 parts of capillary artemisia, 100-300 parts of honeysuckle and 100-300 parts of rhubarb; and then crushing the raw materials and sieving on a 60-mesh sieve; then weighing 10-30 parts by weight of bile acid, 10-30 parts by weight of 2-aminoethanesulfonic acid and 200-500 parts by weight of starch, mixing with the milk veteh, the capillary artemisia, the honeysuckle and the rhubarb which are crushed and sieved, and finally uniformly stirring. The invention has reasonable composition and simple preparation, is used as a medicament for preventing and controlling the grass carp diseases, is harmless and environment-friendly and has remarkable preventing and controlling effects.
Description
Technical field
The present invention relates to field of aquaculture industry, particularly a kind of Chinese medicine composition of preventing and treating the Ctenopharyngodon idellus disease.
Background technology
In recent years, support the fast development of Ctenopharyngodon idellus along with feedstuff, the increase of Ctenopharyngodon idellus cultivation density, the important diseases of Ctenopharyngodon idellus then develops into present Ctenopharyngodon idellus " new three diseases " complication (being Ctenopharyngodon idellus viral hemorrhagic disease, bacterial gill rot disease and liver and gallbladder syndrome) by traditional bacillary " old three diseases " (being erythroderma, gill rot, enteritis disease), the high incidence and the more refractory high mortality that cause Ctenopharyngodon idellus, cause enormous economic loss to the raiser, had a strong impact on vast breed dealer's enthusiasm.At present, also there is certain problem in the medicine that is used for Ctenopharyngodon idellus new three sick controls aspect drug effect, the drug residue, and effect is not good enough.
Therefore, providing a kind of simple, a kind of Chinese medicine composition of preventing and treating the Ctenopharyngodon idellus disease of obvious results for preparing, is one of this field scientific research technical staff important difficult problem of being badly in need of solving.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, a kind of pharmaceutical composition of preventing and treating new three diseases of Ctenopharyngodon idellus is provided, promptly prevent and treat the Chinese medicine composition of Ctenopharyngodon idellus disease.
The technical solution adopted in the present invention is as follows for achieving the above object:
A kind of Chinese medicine composition of preventing and treating the Ctenopharyngodon idellus disease is characterized in that being mixed and made into by following composition by weight: at first take by weighing Radix Astragali 100-300 part, Herba Artemisiae Scopariae 200-400 part, Flos Lonicerae 100-300 part, Radix Et Rhizoma Rhei 100-300 part; The above-mentioned raw materials medicine is taken by weighing the back by weight pulverize, cross 60 mesh sieves; Take by weighing bile acid 10-30 part, taurine 10-30 part, starch 200-500 part more by weight and mix, stir, promptly make with the Radix Astragali, Herba Artemisiae Scopariae, Flos Lonicerae and Radix Et Rhizoma Rhei behind the crushing screening.
The key property of component of the present invention and effect:
Bile acid: bile acid is the general name of a series of cholanic acids of being produced in metabolic process of cholesterol, and complicated component has acidity usually, so be called bile acid.Bile is to produce the mixture that participates in digestion by liver, is made up of moisture, bile acid, cholesterol, fatty acid, phospholipid, bilirubin, vitamin and inorganic salt etc., and wherein bile acid is a main component.Bile acid can effectively promote the digestibility and utilization of lipid material, and can improve the fertility performance of poultry as a kind of novel feed additive.
Taurine: chemistry 2-aminoethyl sulfonic acid by name is the sulfur-containing amino acid with simple chemical constitution, and it is present in the nearly all internal organs of people and mammal in a large number with free form, is the important nutrient of people and animal.One of critical function of taurine is exactly to combine with cholic acid to form taurocholic acid, thereby promotes fatty emulsifying, increases the activity of lipase, and can assist digesting and assimilating of neutral fat, cholesterol, fatsoluble vitamin and other liposoluble substance.Add taurine and also can suppress cholelithiasis formation, promote the effect of bile secretion.
Radix Astragali sweet in the mouth warm in nature is gone into lung, is returned spleen channel.In recent years discover plurality of active ingredients such as containing polysaccharide, Saponin, flavone, aminoacid in the Radix Astragali, these active component all have enhancing antibody to generate and immunoreactive effect, wherein are reported as many with the research to astragalus polysaccharides.Astragalus polysaccharides is one of main active of the Radix Astragali, can be used as immunopotentiating agent or regulator, has effects such as antiviral, antitumor, defying age, radioprotective, anti-stress, antioxidation simultaneously.
Herba Artemisiae Scopariae is the dry aerial parts of feverfew shore thin white silk used in ancient China or Herba Artemisiae Scopariae.The Herba Artemisiae Scopariae main product in Shaanxi, province such as Hebei, Shanxi.Commodity common name capillary wormwood, Shaanxi the product person claim western Herba Artemisiae Scopariae, and is the best in quality.Its succedaneum of HERBA SIPHONOSTEGIAE Chang Zuowei.The chemical constituent more complicated of Herba Artemisiae Scopariae mainly contains Coumarins, chromogen ketone, flavonoid, organic acid, volatile oil, anthraquinone etc.The Herba Artemisiae Scopariae pharmacological action is extensive, except that the function of gallbladder promoting hepatoprotective effect is arranged, also has many-sided activity such as resisting pathogenic microbes, easing pain and diminishing inflammation, blood fat reducing, enhance immunity, antitumor.
Flos Lonicerae is caprifoliaceae plant dry flower or the first flower of opening of band of Radix Ophiopogonis.Flos Lonicerae has another name called Flos Lonicerae, Flos Lonicerae, Flos Lonicerae, Flos Lonicerae, two precious flowers etc., is the Chinese crude drug of using always, mainly is used as medicine with alabastrum at present.Flos Lonicerae returns lung, the heart, stomach warp, and sweet in the mouth cold in nature has the loose effect of wind, antiviral, hepatic cholagogic, hemostasis and enhance immunity of heat-clearing and toxic substances removing, anti-inflammation, cool heat.Chemical constituent comprises organic acid, flavonoid, volatile oil component, triterpene saponin, trace element etc.; Chlorogenic acid belongs to the main antibiotic effective ingredient that organic acid is a Flos Lonicerae.
Radix Et Rhizoma Rhei derives from polygonaceae plant, and bitter in the mouth cold in nature is one of common drug clinically.Radix Et Rhizoma Rhei not only have assault fortified position attack and destroy, the effect of blood circulation promoting and blood stasis dispelling, purging fire and cooling blood, heat-clearing and toxic substances removing, also have effects such as antibiotic, antiviral, antiinflammatory, adjusting immunity, antitumor, hemostasis and health care.Pharmacological research to effective rhubarb component mainly concentrates on anthraquinone analog compound at present, comprises chrysophanic acid, emodin, chrysophanol, aloe-emodin, physcione etc.
Starch: mainly play binding agent.
The beneficial effect that the present invention had:
The present invention complements each other above-mentioned various composition organic assembling, can bring into play the function of various compositions to greatest extent; Preparation technology is simple, and effect is remarkable, is easy to commercial application; New three diseases of Ctenopharyngodon idellus viral hemorrhagic disease, bacterial gill rot disease and liver and gallbladder syndrome are had good preventive and therapeutic effect, and drug residue free.
The specific embodiment
Below in conjunction with specific embodiment technology contents of the present invention is made detailed explanation.
Every part of embodiment 1(is by 1kg)
Take by weighing bile acid 10kg, taurine 10kg, Radix Astragali 100kg, Herba Artemisiae Scopariae 400kg, Flos Lonicerae 200kg, Radix Et Rhizoma Rhei 100kg, starch 480kg by weight; Earlier the crude drug Radix Astragali, Herba Artemisiae Scopariae, Flos Lonicerae, Radix Et Rhizoma Rhei are pulverized, crossed 60 mesh sieves; Mixing with bile acid, taurine, the starch of described amount by said ratio then, stir, promptly make a kind of Chinese medicine composition of preventing and treating the Ctenopharyngodon idellus disease, is the compound medicament composition of effectively preventing and treating new three diseases of Ctenopharyngodon idellus.
The various crude drug that the present invention adopts etc. are the commercially available prod.
Embodiment 2
Take by weighing bile acid 10kg, taurine 20kg, Radix Astragali 300kg, Herba Artemisiae Scopariae 300kg, Flos Lonicerae 100kg, Radix Et Rhizoma Rhei 100kg, starch 370kg by weight; Earlier the crude drug Radix Astragali, Herba Artemisiae Scopariae, Flos Lonicerae, Radix Et Rhizoma Rhei are pulverized, crossed 60 mesh sieves; Mix with bile acid, taurine, the starch of described amount by said ratio then, stir, promptly make.
Other is with embodiment 1.
Embodiment 3
Take by weighing bile acid 20kg, taurine 30kg, Radix Astragali 200kg, Herba Artemisiae Scopariae 400kg, Flos Lonicerae 100kg, Radix Et Rhizoma Rhei 200kg, starch 250kg by weight; Earlier the crude drug Radix Astragali, Herba Artemisiae Scopariae, Flos Lonicerae, Radix Et Rhizoma Rhei are pulverized, crossed 60 mesh sieves; Mix with bile acid, taurine, the starch of described amount by said ratio then, stir, promptly make.
Other is with embodiment 1.
Embodiment 4
Take by weighing bile acid 30kg, taurine 30kg, Radix Astragali 100kg, Herba Artemisiae Scopariae 200kg, Flos Lonicerae 300kg, Radix Et Rhizoma Rhei 300kg, starch 220kg by weight; Earlier the crude drug Radix Astragali, Herba Artemisiae Scopariae, Flos Lonicerae, Radix Et Rhizoma Rhei are pulverized, crossed 60 mesh sieves; Mix with bile acid, taurine, the starch of described amount by said ratio then, stir, promptly make.
Other is with embodiment 1.
Application experiment is given an example:
Sword spring water storehouse, cities and towns is dried moat outside a city wall in the Fengcheng City, the about 150 * 667m of area
2, mean depth 4m puts Ctenopharyngodon idellus winter sheet fingerling 40,000 tails (average 18 tails/kg) in a suitable place to breed.It is dead May 21 to begin to occur a small amount of Ctenopharyngodon idellus morbidity, dead Ctenopharyngodon idellus 130 tails on the 22nd, and dead tail more than 300 on the 23rd, dead Ctenopharyngodon idellus reached tail more than 500 on 24th.The Ctenopharyngodon idellus (150g/ tail) that picks up morbidity is observed, and the sick disease of serious viral hemorrhagic, bacterial gill rot disease in various degree and the concurrent phenomenon of liver and gallbladder syndrome are arranged, and there is a small amount of dactylogyrider parasitism in gill portion.May 25 beginning, (the long-pending and depth of water 2.5 m calculate the water body volume by the food scene, and consumption is 2.5 times of this medicine full pool spilling head) raised and eaten in preceding 20 minutes and splash to every morning in throwing with the medicine that specially kills dactylogyrider; Throwing with chlorine dioxide every afternoon.Raise to eat in preceding 5 minutes and splash, consumption is 3 times of full pool spilling head, and medication water body volume calculation is with the dactylogyrider medicine is identical extremely.Begin to carry out 100kg feedstuff interpolation medicine 100g of the present invention on the same day and throw something and feed, threw something and fed continuously 6 days; Progressively manifest effect, do not occur Ctenopharyngodon idellus death after 29 days, described new three diseases are recurrence more not.
Above-mentioned detailed description of the Chinese medicine composition of this control Ctenopharyngodon idellus disease being carried out with reference to embodiment; be illustrative rather than determinate; can exemplify out several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (1)
1. a Chinese medicine composition of preventing and treating the Ctenopharyngodon idellus disease is characterized in that being mixed and made into by following composition by weight: at first take by weighing Radix Astragali 100-300 part, Herba Artemisiae Scopariae 200-400 part, Flos Lonicerae 100-300 part, Radix Et Rhizoma Rhei 100-300 part; The above-mentioned raw materials medicine is taken by weighing the back by weight pulverize, cross 60 mesh sieves; Take by weighing bile acid 10-30 part, taurine 10-30 part, starch 200-500 part more by weight and mix, stir, promptly make with the Radix Astragali, Herba Artemisiae Scopariae, Flos Lonicerae and Radix Et Rhizoma Rhei behind the crushing screening.
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| CN201010207299XA CN101961391A (en) | 2010-06-23 | 2010-06-23 | Traditional Chinese medicine composition for preventing and controlling grass carp disease |
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| CN201010207299XA CN101961391A (en) | 2010-06-23 | 2010-06-23 | Traditional Chinese medicine composition for preventing and controlling grass carp disease |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429106A (en) * | 2011-10-24 | 2012-05-02 | 天津市晨辉饲料有限公司 | Healthcare feed used for grass carps to overwinter and preparation method for healthcare feed |
| CN102640871A (en) * | 2012-04-27 | 2012-08-22 | 杨洪星 | Feed additive for aquatic livestock |
| CN103055047A (en) * | 2012-12-04 | 2013-04-24 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating infectious hemorrhagic disease of grass carp and preparation method thereof |
| CN103768205A (en) * | 2012-10-24 | 2014-05-07 | 天津中敖生物科技有限公司 | Traditional Chinese medicine composition for treating freshwater fish bacterial liver-gall syndrome and preparation method of traditional Chinese medicine composition |
| CN103815201A (en) * | 2014-03-04 | 2014-05-28 | 明建华 | Anti-stress and puffed mixed feed for ctenopharyngodon idellus and production method for feed |
| CN104187071A (en) * | 2014-07-30 | 2014-12-10 | 严中明 | Fish feed for preventing and treating hemorrhagic diseases of grass carps |
| CN105724834A (en) * | 2016-02-26 | 2016-07-06 | 广东海因特生物技术集团有限公司 | Multi-vitamin premix for preventing hemorragic diseases of grass carp |
-
2010
- 2010-06-23 CN CN201010207299XA patent/CN101961391A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429106A (en) * | 2011-10-24 | 2012-05-02 | 天津市晨辉饲料有限公司 | Healthcare feed used for grass carps to overwinter and preparation method for healthcare feed |
| CN102640871A (en) * | 2012-04-27 | 2012-08-22 | 杨洪星 | Feed additive for aquatic livestock |
| CN103768205A (en) * | 2012-10-24 | 2014-05-07 | 天津中敖生物科技有限公司 | Traditional Chinese medicine composition for treating freshwater fish bacterial liver-gall syndrome and preparation method of traditional Chinese medicine composition |
| CN103055047A (en) * | 2012-12-04 | 2013-04-24 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating infectious hemorrhagic disease of grass carp and preparation method thereof |
| CN103055047B (en) * | 2012-12-04 | 2014-12-10 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating infectious hemorrhagic disease of grass carp and preparation method thereof |
| CN103815201A (en) * | 2014-03-04 | 2014-05-28 | 明建华 | Anti-stress and puffed mixed feed for ctenopharyngodon idellus and production method for feed |
| CN103815201B (en) * | 2014-03-04 | 2015-06-24 | 湖州师范学院 | Anti-stress and puffed mixed feed for ctenopharyngodon idellus and production method for feed |
| CN104187071A (en) * | 2014-07-30 | 2014-12-10 | 严中明 | Fish feed for preventing and treating hemorrhagic diseases of grass carps |
| CN105724834A (en) * | 2016-02-26 | 2016-07-06 | 广东海因特生物技术集团有限公司 | Multi-vitamin premix for preventing hemorragic diseases of grass carp |
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Application publication date: 20110202 |