CN102414314A - 用于生产丙酮的细胞和方法 - Google Patents

用于生产丙酮的细胞和方法 Download PDF

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Publication number
CN102414314A
CN102414314A CN2010800177745A CN201080017774A CN102414314A CN 102414314 A CN102414314 A CN 102414314A CN 2010800177745 A CN2010800177745 A CN 2010800177745A CN 201080017774 A CN201080017774 A CN 201080017774A CN 102414314 A CN102414314 A CN 102414314A
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China
Prior art keywords
acetone
enzyme
clostridium
cell
coa
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Pending
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CN2010800177745A
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English (en)
Chinese (zh)
Inventor
U.贝克
G.格伦德
M.奥尔舍尔
K.多德雷尔
G.勒登
G.布兰
P.迪雷
S.图姆
H.J巴尔
R-J.菲舍尔
A.梅伊
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Evonik Operations GmbH
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Evonik Degussa GmbH
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Publication of CN102414314A publication Critical patent/CN102414314A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/13—Transferases (2.) transferring sulfur containing groups (2.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C12P7/28—Acetone-containing products
    • C12P7/30—Acetone-containing products produced from substrate containing inorganic compounds other than water
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01009—Acetyl-CoA C-acetyltransferase (2.3.1.9)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN2010800177745A 2009-04-23 2010-02-23 用于生产丙酮的细胞和方法 Pending CN102414314A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102009002583.9 2009-04-23
DE102009002583A DE102009002583A1 (de) 2009-04-23 2009-04-23 Zellen und Verfahren zur Herstellung von Aceton
PCT/EP2010/052244 WO2010121849A1 (de) 2009-04-23 2010-02-23 Zellen und verfahren zur herstellung von aceton

Publications (1)

Publication Number Publication Date
CN102414314A true CN102414314A (zh) 2012-04-11

Family

ID=42103849

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800177745A Pending CN102414314A (zh) 2009-04-23 2010-02-23 用于生产丙酮的细胞和方法

Country Status (9)

Country Link
US (1) US9453210B2 (enExample)
EP (1) EP2421960B1 (enExample)
JP (1) JP5805073B2 (enExample)
CN (1) CN102414314A (enExample)
AU (1) AU2010241185B2 (enExample)
BR (1) BRPI1013430A2 (enExample)
DE (1) DE102009002583A1 (enExample)
ES (1) ES2639224T3 (enExample)
WO (1) WO2010121849A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105821084A (zh) * 2015-01-28 2016-08-03 赢创德固赛有限公司 生产醇的好氧方法
CN107404882A (zh) * 2015-02-27 2017-11-28 白狗实验室有限公司 用于生产丙酮、异丙醇、丁酸、其他生物产品及其混合物的混合营养发酵方法
CN112608935A (zh) * 2020-12-18 2021-04-06 北京化工大学 一种改造乙酸梭菌代谢途径产丙酮的方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5397136B2 (ja) * 2009-09-30 2014-01-22 住友電気工業株式会社 Ｉｉｉ族窒化物半導体レーザ素子、及びｉｉｉ族窒化物半導体レーザ素子を作製する方法
DE102010062587A1 (de) 2010-12-08 2012-06-14 Evonik Degussa Gmbh Verfahren zur Herstellung von Isophoron
US9410130B2 (en) 2011-02-25 2016-08-09 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
PL2678432T4 (pl) * 2011-02-25 2019-05-31 Lanzatech New Zealand Ltd Rekombinowane mikroorganizmy i ich zastosowania
US9365868B2 (en) 2011-02-25 2016-06-14 Lanzatech New Zealand Limited Fermentation process for producing isopropanol using a recombinant microorganism
DE102011075777A1 (de) 2011-05-13 2012-11-15 Evonik Degussa Gmbh Verfahren zur Herstellung von Isophoron in Gegenwart mindestens eines Entschäumers in der Abwasserkolonne im Aufarbeitungsteil
DE102011077705A1 (de) 2011-06-17 2012-12-20 Evonik Degussa Gmbh Mikrobielles Verfahren zur Herstellung niedermolekularer, organischer Verbindungen umfassend die Produktabsorption durch Isophoron
AU2013215706B2 (en) 2012-01-31 2014-03-27 Lanzatech Nz, Inc. Recombinant microorganisms and methods of use thereof
WO2013181647A2 (en) 2012-06-01 2013-12-05 Danisco Us Inc. Compositions and methods of producing isoprene and/or industrrial bio-products using anaerobic microorganisms
KR102157256B1 (ko) * 2013-03-15 2020-09-18 란자테크 뉴질랜드 리미티드 미생물 발효에서 대사산물 생산 조절 시스템 및 방법
KR101750293B1 (ko) 2015-03-04 2017-06-26 한국과학기술연구원 이산화탄소로부터의 아세톤 생성능을 갖는 형질전환된 시네코코커스 일롱게투스 균주
EP3348646A1 (de) 2017-01-17 2018-07-18 Evonik Degussa GmbH Mikrobielles verfahren zur herstellung von aceton, isopropanol, butanol und/oder ethanol umfassend die produktabsorption durch wasser
WO2021154826A1 (en) * 2020-01-29 2021-08-05 Jupeng Bio (Hk) Limited Process for controlling organic acid ratios in a carbon dioxide bioconversion process
WO2024231219A1 (en) 2023-05-11 2024-11-14 Evonik Operations Gmbh Biotechnological production of acetone

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NL301993A (enExample) 1962-12-18
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
BR9917289B1 (pt) 1999-05-07 2010-09-08 processo para produção de etanol a partir de cepas clostridium.
DE60121335T2 (de) 2000-07-25 2007-08-02 Emmaus Foundation, Inc., Fayetteville Verfahren zur steigerung der ethanolproduktion bei der mikrobiellen fermentation
US20070275447A1 (en) 2006-05-25 2007-11-29 Lewis Randy S Indirect or direct fermentation of biomass to fuel alcohol
US7704723B2 (en) 2006-08-31 2010-04-27 The Board Of Regents For Oklahoma State University Isolation and characterization of novel clostridial species
BRPI0816161A2 (pt) * 2007-08-29 2014-10-14 Res Inst Innovative Tech Earth Transformante capaz de produzir isopropanol
JP2011500031A (ja) * 2007-10-12 2011-01-06 ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア イソプロパノールを生産するように操作された微生物
DE102007052463A1 (de) * 2007-11-02 2009-05-07 Evonik Degussa Gmbh Fermentative Gewinnung von Aceton aus erneuerbaren Rohstoffen mittels neuen Stoffwechselweges
DE102010062587A1 (de) 2010-12-08 2012-06-14 Evonik Degussa Gmbh Verfahren zur Herstellung von Isophoron

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BYUNG HONG KIM ET AL: "Control of Carbon and Electron Flow in Clostridium acetobutylicum Fermentations: Utilization of Carbon Monoxide to Inhibit Hydrogen Production and to Enhance Butanol Yields.", 《APPL.ENVIRON.MICROBIOL.》 *
LEE D. MERMELSTEIN ET AL: "MetaboIic Engineering of Clostridium acetobutylicum ATCC 824 for Increased Solvent Production by Enhancement of Acetone Formation Enzyme Activities Using a Synthetic Acetone Operon.", 《BIOTECHNOLOGY AND BIOENGINEERING》 *
LOURDES L. BERMEJO等: "Expression of Clostridium acetobutylicum ATCC 824 Genes in Escherichia coli for Acetone Production and Acetate Detoxification", 《APPLIED AND ENVIRONMENTAL MICROBIOLOGY》 *
MOLLAH A H ET AL: "The influence of hydeogen carbon dioxide and dilution reta on the continuous fermentation of acetone butanol", 《APPLIED MICROBIOLOGY AND BIOTECHNOLOGY》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105821084A (zh) * 2015-01-28 2016-08-03 赢创德固赛有限公司 生产醇的好氧方法
CN105821084B (zh) * 2015-01-28 2021-02-26 赢创运营有限公司 生产醇的好氧方法
CN107404882A (zh) * 2015-02-27 2017-11-28 白狗实验室有限公司 用于生产丙酮、异丙醇、丁酸、其他生物产品及其混合物的混合营养发酵方法
CN112608935A (zh) * 2020-12-18 2021-04-06 北京化工大学 一种改造乙酸梭菌代谢途径产丙酮的方法

Also Published As

Publication number Publication date
US20120101304A1 (en) 2012-04-26
ES2639224T3 (es) 2017-10-25
WO2010121849A1 (de) 2010-10-28
DE102009002583A1 (de) 2010-10-28
JP2012524529A (ja) 2012-10-18
EP2421960B1 (de) 2017-07-19
AU2010241185B2 (en) 2016-03-10
BRPI1013430A2 (pt) 2015-09-01
JP5805073B2 (ja) 2015-11-04
EP2421960A1 (de) 2012-02-29
US9453210B2 (en) 2016-09-27
AU2010241185A1 (en) 2011-10-27

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