CN102357070A - Hydrolyzed silk protein/ recombinant human Epidermal Growth Factor (rhEGF) compound skin care facial mask and preparation method thereof - Google Patents

Hydrolyzed silk protein/ recombinant human Epidermal Growth Factor (rhEGF) compound skin care facial mask and preparation method thereof Download PDF

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CN102357070A
CN102357070A CN2011103541392A CN201110354139A CN102357070A CN 102357070 A CN102357070 A CN 102357070A CN 2011103541392 A CN2011103541392 A CN 2011103541392A CN 201110354139 A CN201110354139 A CN 201110354139A CN 102357070 A CN102357070 A CN 102357070A
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kilograms
rhegf
skin
phase materials
kilogram
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CN102357070B (en
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孙百力
韩敏
杨平顺
张泽奇
顾葵
李建超
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Shenzhen Rongda Biotechnology Co.,Ltd.
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SHENZHEN GENE BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention discloses a hydrolyzed silk protein/ recombinant human Epidermal Growth Factor (rhEGF) compound skin care facial mask and a preparation method thereof. The hydrolyzed silk protein/ rhEGF compound skin care facial mask is prepared by components of 18 materials, and comprises two main components including, by weight, 1.5% to 2.5% of hydrolyzed silk protein and 0.01% to 0.1% of rhEGF. The skin care facial mask utilizes natural silk which contains a plurality of amino acids and proteins, and has the skin care effect of whitening, moisture preservation, skin smoothing, skin ageing retarding and the like. Each piece of silk facial mask converges rich silk protein essence, rhEGF and whitening moisture preservation components, provides dense whitening moistening for the skin, instantly brightens the skin color, enables the skin to be white and tender, solves the problems of withered and yellow skin color, dryness, roughness, fine wrinkles, elasticity lacking, thick pores and the like, retains corneum moisture and integrity of a fiber structure, enables dark skin to reproduce silky smoothness and regain the touching color.

Description

A kind of hydrolyzed silkworm silk albumen/rhEGF composition skin-care facial film and preparation method thereof
Technical field
The present invention relates to a kind of skin protection cosmetics, especially a kind of hydrolyzed silkworm silk albumen/rhEGF composition skin-care facial film and preparation method thereof.
Background technology
For the aging that slows down face skin, multiple mode is arranged, for example: the use of diet control, defying age elite etc.And the facial film that contains hydrolyzed silkworm silk albumen/rhEGF compositions directly acts on the skin after the cleaning, can infiltrate through skin more effectively, but effectively real, the anti-ageing face mask that has no side effect is rare.
Summary of the invention
The technical problem that the present invention will solve provides a kind of goodish oxidation resistance that has, and can slow down skin aging, prevention is arranged and subtract light facial microgroove, the hydrolyzed silkworm silk albumen of the delaying senility of unique effects such as mottle/rhEGF composition skin-care facial film.
The present invention also provides the method for preparing of a kind of said hydrolyzed fibroin/rhEGF composition skin-care facial film simultaneously.
To achieve these goals, the technical scheme of the present invention's employing is that a kind of hydrolyzed silkworm silk albumen/rhEGF composition skin-care facial film is by weight percentage by following constituent content:
The A phase materials:
(1) deionized water 53.17-76.66%;
(2) glycerol 3.5-4.5%;
(3) trehalose 2.6-8.8%;
(4) trimethyl glycine 1.0-3.0%;
(5) hydrolyzed silkworm silk albumen 1.5-2.5%;
(6) pentanediol 3.0-6.0%;
The B phase materials:
(7) active yeast extract 0.1-2.1%;
(8) Flos Rosae Rugosae extracting solution 1.0-2.0%;
(9) aloe gel 1:1 .5-2.5%;
(10) chlorella elite 1.3-2.3%;
(11) Fructus Mori elite 2.0-3.0%;
(12) L-vitamin C 4.0-5.5%;
The C phase materials:
(13) six victory peptide 1.2-2.2%;
(14) Wushengtai 0.1-0.8%;
(15) taurine 0.5-1.4%;
(16) hyaluronic acid 0.02-0.1%;
(17) Herba Lysimachiae foenum-graeci quintessence oil 0.01.-0.03%;
(18)rhEGF 0.01-0.1%。
Preferably, described hydrolyzed silkworm silk albumen/rhEGF composition skin-care facial film by following constituent content is by weight percentage:
The A phase materials:
(1) deionized water 53.17-76.67%;
(2) glycerol 2.7-8.6%;
(3) trehalose 1.0-5.0%;
(4) trimethyl glycine 0-3.0%;
(5) hydrolyzed silkworm silk albumen 1.0-6.0%;
(6) pentanediol 1.0-4.0%;
The B phase materials:
(7) active yeast extract 0.1-2.1%;
(8) Flos Rosae Rugosae extracting solution 1.0-2.0%;
(9) Aloe gel 0.5-4.5%;
(10) chlorella elite 1.0-4.3%;
(11) Fructus Mori elite 1.0-2.0%;
(12) L-vitamin C 1.0-5.5%;
The C phase materials:
(13) six victory peptide 0.2-2.0%;
(14) Wushengtai 0.1-1.8%;
(15) taurine 0.5-4.4%;
(16) hyaluronic acid 0.05-0.1%;
(17) Herba Lysimachiae foenum-graeci quintessence oil 0.01.-0.03%;
(18)rhEGF 0.05-0.3%。
The method for preparing of a kind of said hydrolyzed fibroin/rhEGF composition skin-care facial film may further comprise the steps:
(1) by each phase raw material of above-mentioned percentage by weight weighing;
(2) with each component of A phase materials mix stir after, add emulsifying pot internal heating to 80 ℃-85 ℃, under the vacuum state, constant temperature sterilization 25-35 minute;
(3) step (2) products therefrom is cooled to 40 ℃ and adds each component of B phase materials successively, stir transparent;
(4) step (3) products therefrom is cooled to 35 ℃ and adds each component of C phase materials successively, stir;
(5) 35 ℃ of whipping steps (4) products therefrom detected qualified back discharging after 10 minutes.
The invention has the beneficial effects as follows that a kind of composition skin-care article of delaying senility contain deionized water, glycerol, trehalose in every part; Trimethyl glycine, hydrolyzed silkworm silk albumen, pentanediol, active yeast extract, Flos Rosae Rugosae extracting solution; Aloe gel, chlorella elite, Fructus Mori elite, L-vitamin C, six victory peptides; Wushengtai, taurine, hyaluronic acid, Herba Lysimachiae foenum-graeci quintessence oil, oligopeptide-1.After thorough clean, this facial film is applied to face, treats to clean with clean product after 20 minutes.Goodish oxidation resistance is originally arranged, can slow down skin aging, prevention is arranged and subtract light facial microgroove, the unique effects of mottle.
The aging of skin can bring facial wrinkles, the facial beautiful problem of various influences such as mottle.Active ingredient among the present invention can be through the distinctive hydration of keratin by skin absorbs, for skin provides competent moisture and prevents that the water evaporates in the keratodermatitis from reducing.Make additional moist nutrition skin-protection composition be easy to absorb, can keep facial and moisten, avoid the skin of face accelerated ageing, reduce the appearance of skin of face matter wrinkle.In addition, unique antioxidation factor can fundamentally make the skin anti-aging ability increase delaying skin aging.
The specific embodiment
Embodiment 1
The raw material total amount is 100 kilograms.Wherein, the A phase materials is: 3.5 kilograms of glycerol, 2.6 kilograms of trehaloses, 1.0 kilograms of trimethyl glycine, 1.5 kilograms in hydrolyzed silkworm silk albumen, 3.0 kilograms of pentanediols; The B phase materials is: 0.1 kilogram of active yeast extract, 1.0 kilograms of Flos Rosae Rugosae extracting solution, aloe gel 1:1 .5 kilogram, 1.3 kilograms of chlorella elite, 2.0 kilograms of Fructus Mori elite, L-vitamin C4.0 kilogram; The C phase materials is: 1.2 kilograms of six victory peptides, 0.1 kilogram of Wushengtai, 0.5 kilogram of taurine, 0.02 kilogram of hyaluronic acid, 0.01 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, 0.01 kilogram of rhEGF; Surplus is supplied by the deionized water of A phase.
Preparation technology:
(1) by each phase raw material of above-mentioned percentage by weight weighing;
(2) with each component of A phase materials mix stir after, add emulsifying pot internal heating to 80 ℃-85 ℃, under the vacuum state, constant temperature sterilization 25-35 minute;
(3) step (2) products therefrom is cooled to 40 ℃ and adds each component of B phase materials successively, stir transparent;
(4) step (3) products therefrom is cooled to 35 ℃ and adds each component of C phase materials successively, stir;
(5) 35 ℃ of whipping steps (4) products therefrom detected qualified back discharging after 10 minutes.
Embodiment 2
The raw material total amount is 100 kilograms.Wherein, A phase materials: 4.0 kilograms of glycerol, 3.1 kilograms of trehaloses, 1.5 kilograms of trimethyl glycine, 2.0 kilograms in hydrolyzed silkworm silk albumen, 3.5 kilograms of pentanediols; The B phase materials is: 0.6 kilogram of active yeast extract, 1.5 kilograms of Flos Rosae Rugosae extracting solution, 2.0 kilograms of Aloe gels, 1.8 kilograms of chlorella elite, 2.5 kilograms of Fructus Mori elite, L-vitamin C4.5 kilogram; The C phase materials is: 1.7 kilograms of six victory peptides, 0.6 kilogram of Wushengtai, 1.0 kilograms of taurines, 0.07 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.06 kilogram; Surplus is supplied by the deionized water of A phase.
Preparation technology is with embodiment 1.
Embodiment 3
The raw material total amount is 100 kilograms.Wherein, A phase materials: 4.5 kilograms of glycerol, 3.6 kilograms of trehaloses, 2.0 kilograms of trimethyl glycine, 2.5 kilograms in hydrolyzed silkworm silk albumen, 4.0 kilograms of pentanediols; The B phase materials is: 1.1 kilograms of active yeast extracts, 2.0 kilograms of Flos Rosae Rugosae extracting solution, 2.5 kilograms of Aloe gels, 2.3 kilograms of chlorella elite, 3.0 kilograms of Fructus Mori elite, L-vitamin C5.0 kilogram; The C phase materials is: 2.2 kilograms of six victory peptides, 0.8 kilogram of Wushengtai, 1.4 kilograms of taurines, 0.1 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.1 kilogram; Surplus is supplied by the deionized water of A phase.
Preparation technology is with embodiment 1.
Embodiment 4
The raw material total amount is 100 kilograms.Wherein, A phase materials: 4.5 kilograms of glycerol, 4.1 kilograms of trehaloses, 2.5 kilograms of trimethyl glycine, 2.5 kilograms in hydrolyzed silkworm silk albumen, 4.5 kilograms of pentanediols; The B phase materials is: 1.6 kilograms of active yeast extracts, 2.0 kilograms of Flos Rosae Rugosae extracting solution, 2.5 kilograms of Aloe gels, 2.3 kilograms of chlorella elite, 3.0 kilograms of Fructus Mori elite, L-vitamin C5.5 kilogram; The C phase materials is: 2.2 kilograms of six victory peptides, 0.8 kilogram of Wushengtai, 1.4 kilograms of taurines, 0.1 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.1 kilogram; Surplus is supplied by the deionized water of A phase.
Preparation technology is with embodiment 1.
Embodiment 5
The raw material total amount is 100 kilograms.Wherein, A phase materials: 4.5 kilograms of glycerol, 4.6 kilograms of trehaloses, 3.0 kilograms of trimethyl glycine, 2.5 kilograms in hydrolyzed silkworm silk albumen, 5.0 kilograms of pentanediols; The B phase materials is: 2.1 kilograms of active yeast extracts, 2.0 kilograms of Flos Rosae Rugosae extracting solution, 2.5 kilograms of Aloe gels, 2.3 kilograms of chlorella elite, 3.0 kilograms of Fructus Mori elite, L-vitamin C5.5 kilogram; The C phase materials is: 2.2 kilograms of six victory peptides, 0.8 kilogram of Wushengtai, 1.4 kilograms of taurines, 0.1 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.1 kilogram; Surplus is supplied by the deionized water of A phase.
Preparation technology is with embodiment 1.
Embodiment 6
The raw material total amount is 100 kilograms.Wherein, A phase materials: 4.5 kilograms of glycerol, 5.1 kilograms of trehaloses, 3.0 kilograms of trimethyl glycine, 2.5 kilograms in hydrolyzed silkworm silk albumen, 5.5 kilograms of pentanediols; The B phase materials is: 2.1 kilograms of active yeast extracts, 2.0 kilograms of Flos Rosae Rugosae extracting solution, 2.5 kilograms of Aloe gels, 2.3 kilograms of chlorella elite, 3.0 kilograms of Fructus Mori elite, L-vitamin C5.5 kilogram; The C phase materials is: 2.2 kilograms of six victory peptides, 0.8 kilogram of Wushengtai, 1.4 kilograms of taurines, 0.1 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.1 kilogram; Surplus is supplied by the deionized water of A phase.
Preparation technology is with embodiment 1.
Embodiment 7
The raw material total amount is 100 kilograms.Wherein, A phase materials: 4.5 kilograms of glycerol, 5.6 kilograms of trehaloses, 3.0 kilograms of trimethyl glycine, 2.5 kilograms in hydrolyzed silkworm silk albumen, 6.0 kilograms of pentanediols; The B phase materials is: 2.1 kilograms of active yeast extracts, 2.0 kilograms of Flos Rosae Rugosae extracting solution, 2.5 kilograms of Aloe gels, 2.3 kilograms of chlorella elite, 3.0 kilograms of Fructus Mori elite, L-vitamin C5.5 kilogram; The C phase materials is: 2.2 kilograms of six victory peptides, 0.8 kilogram of Wushengtai, 1.4 kilograms of taurines, 0.1 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.1 kilogram; Surplus is supplied by the deionized water of A phase.
Preparation technology is with embodiment 1.
Embodiment 8
The raw material total amount is 100 kilograms.Wherein, A phase materials: 4.5 kilograms of glycerol, 6.1 kilograms of trehaloses, 3.0 kilograms of trimethyl glycine, 2.5 kilograms in hydrolyzed silkworm silk albumen, 6.0 kilograms of pentanediols; The B phase materials is: 2.1 kilograms of active yeast extracts, 2.0 kilograms of Flos Rosae Rugosae extracting solution, 2.5 kilograms of Aloe gels, 2.3 kilograms of chlorella elite, 3.0 kilograms of Fructus Mori elite, L-vitamin C5.5 kilogram; The C phase materials is: 2.2 kilograms of six victory peptides, 0.8 kilogram of Wushengtai, 1.4 kilograms of taurines, 0.1 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.1 kilogram; Surplus is supplied by the deionized water of A phase.Preparation technology is with embodiment 1.
Embodiment 9
The raw material total amount is 100 kilograms.Wherein, A phase materials: 4.5 kilograms of glycerol, 6.6 kilograms of trehaloses, 3.0 kilograms of trimethyl glycine, 2.5 kilograms in hydrolyzed silkworm silk albumen, 6.0 kilograms of pentanediols; The B phase materials is: 2.1 kilograms of active yeast extracts, 2.0 kilograms of Flos Rosae Rugosae extracting solution, 2.5 kilograms of Aloe gels, 2.3 kilograms of chlorella elite, 3.0 kilograms of Fructus Mori elite, L-vitamin C5.5 kilogram; The C phase materials is: 2.2 kilograms of six victory peptides, 0.8 kilogram of Wushengtai, 1.4 kilograms of taurines, 0.1 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.1 kilogram; Surplus is supplied by the deionized water of A phase.
Preparation technology is with embodiment 1.
Embodiment 10
The raw material total amount is 100 kilograms.Wherein, A phase materials: 4.5 kilograms of glycerol, 7.1 kilograms of trehaloses, 3.0 kilograms of trimethyl glycine, 2.5 kilograms in hydrolyzed silkworm silk albumen, 6.0 kilograms of pentanediols; The B phase materials is: 2.1 kilograms of active yeast extracts, 2.0 kilograms of Flos Rosae Rugosae extracting solution, 2.5 kilograms of Aloe gels, 2.3 kilograms of chlorella elite, 3.0 kilograms of Fructus Mori elite, L-vitamin C5.5 kilogram; The C phase materials is: 2.2 kilograms of six victory peptides, 0.8 kilogram of Wushengtai, 1.4 kilograms of taurines, 0.1 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.1 kilogram; Surplus is supplied by the deionized water of A phase.
Preparation technology is with embodiment 1.
Embodiment 11
The raw material total amount is 100 kilograms.Wherein, A phase materials: 2.7 kilograms of glycerol, 1.0 kilograms of trehaloses, 1.0 kilograms in hydrolyzed silkworm silk albumen, 1.0 kilograms of pentanediols; The B phase materials is: 0.1 kilogram of active yeast extract, 1.0 kilograms of Flos Rosae Rugosae extracting solution, 0.5 kilogram of Aloe gel, 1.0 kilograms of chlorella elite, 1.0 kilograms of Fructus Mori elite, L-vitamin C1.0 kilogram; The C phase materials is: 0.2 kilogram of six victory peptide, 0.1 kilogram of Wushengtai, 0.5 kilogram of taurine, 0.02 kilogram of hyaluronic acid, 0.01 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, 0.01 kilogram of rhEGF; Surplus is supplied by the deionized water of A phase.Preparation technology is with embodiment 1.
Embodiment 12
The raw material total amount is 100 kilograms.Wherein, A phase materials: 8.6 kilograms of glycerol, 8.8 kilograms of trehaloses, 3.0 kilograms of trimethyl glycine, 6.0 kilograms in hydrolyzed silkworm silk albumen, 6.0 kilograms of pentanediols; The B phase materials is: 2.1 kilograms of active yeast extracts, 2.0 kilograms of Flos Rosae Rugosae extracting solution, 4.5 kilograms of Aloe gels, 4.3 kilograms of chlorella elite, 3.0 kilograms of Fructus Mori elite, L-vitamin C5.5 kilogram; The C phase materials is: 2.2 kilograms of six victory peptides, 1.8 kilograms of Wushengtais, 4.4 kilograms of taurines, 0.1 kilogram of hyaluronic acid, 0.03 kilogram of Herba Lysimachiae foenum-graeci quintessence oil, rhEGF0.3 kilogram; Surplus is supplied by the deionized water of A phase.
Preparation technology is with embodiment 1.
Only be preferred implementation of the present invention in sum, should be understood that for the person of ordinary skill of the art that under the prerequisite that does not break away from the present invention's design, can also make several distortion and improvement, these also should be regarded as within protection scope of the present invention.

Claims (3)

1. hydrolyzed silkworm silk albumen/rhEGF composition skin-care facial film is characterized in that, by following constituent content is by weight percentage:
The A phase materials:
(1) deionized water 53.17-76.66%;
(2) glycerol 3.5-4.5%;
(3) trehalose 2.6-8.8%;
(4) trimethyl glycine 1.0-3.0%;
(5) hydrolyzed silkworm silk albumen 1.5-2.5%;
(6) pentanediol 3.0-6.0%;
The B phase materials:
(7) active yeast extract 0.1-2.1%;
(8) Flos Rosae Rugosae extracting solution 1.0-2.0%;
(9) aloe gel 1:1 .5-2.5%;
(10) chlorella elite 1.3-2.3%;
(11) Fructus Mori elite 2.0-3.0%;
(12) L-vitamin C 4.0-5.5%;
The C phase materials:
(13) six victory peptide 1.2-2.2%;
(14) Wushengtai 0.1-0.8%;
(15) taurine 0.5-1.4%;
(16) hyaluronic acid 0.02-0.1%;
(17) Herba Lysimachiae foenum-graeci quintessence oil 0.01.-0.03%;
(18)rhEGF 0.01-0.1%。
2. a kind of hydrolyzed silkworm silk albumen according to claim 1/rhEGF composition skin-care facial film is characterized in that, by following constituent content is by weight percentage:
The A phase materials:
(1) deionized water 53.17-76.67%;
(2) glycerol 2.7-8.6%;
(3) trehalose 1.0-5.0%;
(4) trimethyl glycine 0-3.0%;
(5) hydrolyzed silkworm silk albumen 1.0-6.0%;
(6) pentanediol 1.0-4.0%;
The B phase materials:
(7) active yeast extract 0.1-2.1%;
(8) Flos Rosae Rugosae extracting solution 1.0-2.0%;
(9) Aloe gel 0.5-4.5%;
(10) chlorella elite 1.0-4.3%;
(11) Fructus Mori elite 1.0-2.0%;
(12) L-vitamin C 1.0-5.5%;
The C phase materials:
(13) six victory peptide 0.2-2.0%;
(14) Wushengtai 0.1-1.8%;
(15) taurine 0.5-4.4%;
(16) hyaluronic acid 0.05-0.1%;
(17) Herba Lysimachiae foenum-graeci quintessence oil 0.01.-0.03%;
(18)rhEGF 0.05-0.3%。
3. the method for preparing of a kind of hydrolyzed silkworm silk albumen according to claim 1 and 2/rhEGF composition skin-care facial film is characterized in that, may further comprise the steps:
(1) by claim 1 or each phase raw material of percentage by weight weighing of 2;
(2) with each component of A phase materials mix stir after, add emulsifying pot internal heating to 80 ℃-85 ℃, under the vacuum state, constant temperature sterilization 25-35 minute;
(3) step (2) products therefrom is cooled to 40 ℃ and adds each component of B phase materials successively, stir transparent;
(4) step (3) products therefrom is cooled to 35 ℃ and adds each component of C phase materials successively, stir;
(5) 35 ℃ of whipping steps (4) products therefrom detected qualified back discharging after 10 minutes.
CN 201110354139 2011-11-10 2011-11-10 Hydrolyzed silk protein/ recombinant human Epidermal Growth Factor (rhEGF) compound skin care facial mask and preparation method thereof Active CN102357070B (en)

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