CN101921279A - 螺环杂环衍生物及其应用方法 - Google Patents
螺环杂环衍生物及其应用方法 Download PDFInfo
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- CN101921279A CN101921279A CN2009101634060A CN200910163406A CN101921279A CN 101921279 A CN101921279 A CN 101921279A CN 2009101634060 A CN2009101634060 A CN 2009101634060A CN 200910163406 A CN200910163406 A CN 200910163406A CN 101921279 A CN101921279 A CN 101921279A
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- compound
- alkyl
- aryl
- chromene
- phenyl
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50786403P | 2003-10-01 | 2003-10-01 | |
| US60/507,864 | 2003-10-01 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004800356909A Division CN100549004C (zh) | 2003-10-01 | 2004-10-01 | 螺环杂环衍生物及其应用方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101921279A true CN101921279A (zh) | 2010-12-22 |
Family
ID=34421676
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009101634060A Pending CN101921279A (zh) | 2003-10-01 | 2004-10-01 | 螺环杂环衍生物及其应用方法 |
| CNB2004800356909A Expired - Fee Related CN100549004C (zh) | 2003-10-01 | 2004-10-01 | 螺环杂环衍生物及其应用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004800356909A Expired - Fee Related CN100549004C (zh) | 2003-10-01 | 2004-10-01 | 螺环杂环衍生物及其应用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US7338962B2 (https=) |
| EP (1) | EP1675847B1 (https=) |
| JP (2) | JP4976134B2 (https=) |
| KR (2) | KR20140015122A (https=) |
| CN (2) | CN101921279A (https=) |
| AU (1) | AU2004278414B2 (https=) |
| BR (1) | BRPI0415165A (https=) |
| CA (1) | CA2541014A1 (https=) |
| CO (1) | CO5690640A2 (https=) |
| IL (2) | IL174702A (https=) |
| NZ (3) | NZ546834A (https=) |
| WO (1) | WO2005033073A2 (https=) |
| ZA (1) | ZA200603414B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN121405620A (zh) * | 2025-12-30 | 2026-01-27 | 山东佰隆医药有限公司 | 一种2-氰基-5-溴吡啶的合成方法 |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2160899A (en) * | 1997-12-11 | 1999-06-28 | Janssen Pharmaceutica N.V. | Retinoic acid mimetic anilides |
| CN101921279A (zh) * | 2003-10-01 | 2010-12-22 | 阿得罗公司 | 螺环杂环衍生物及其应用方法 |
| US7598261B2 (en) * | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| JP2009509928A (ja) | 2005-09-01 | 2009-03-12 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | カリウムチャンネル開口剤としての新規ベンゾピラン誘導体 |
| WO2007027780A2 (en) * | 2005-09-01 | 2007-03-08 | Janssen Pharmaceutica N.V. | Benzopyran and pyranopyridine derivatives as potassium channel openers |
| US7576207B2 (en) * | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| JP2009536175A (ja) * | 2006-05-05 | 2009-10-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 特定の細胞サイクル酵素の阻害剤としてのスピロ−(tho)ベンゾピラン−2,4’−ピペリジン−及びシクロヘキサン誘導体 |
| WO2008033299A2 (en) * | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of n-containing spirocompounds for the enhancement of cognitive function |
| TWI425945B (zh) * | 2007-05-28 | 2014-02-11 | Seldar Pharma Inc | 四氫異喹啉-1-酮衍生物或其鹽 |
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| MX2010008375A (es) * | 2008-01-30 | 2011-03-04 | Cephalon Inc Star | Derivados de piperidina espirocíclicos substituidos como ligandos de receptores de histamina-3 (h3). |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN121405620A (zh) * | 2025-12-30 | 2026-01-27 | 山东佰隆医药有限公司 | 一种2-氰基-5-溴吡啶的合成方法 |
| CN121405620B (zh) * | 2025-12-30 | 2026-03-20 | 山东佰隆医药有限公司 | 一种2-氰基-5-溴吡啶的合成方法 |
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