CN101910202B - 用于固定生物物质的生物相容性三维基质 - Google Patents

用于固定生物物质的生物相容性三维基质 Download PDF

Info

Publication number
CN101910202B
CN101910202B CN200880124134.7A CN200880124134A CN101910202B CN 101910202 B CN101910202 B CN 101910202B CN 200880124134 A CN200880124134 A CN 200880124134A CN 101910202 B CN101910202 B CN 101910202B
Authority
CN
China
Prior art keywords
carrier
group
silane
antibody
aqueous solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200880124134.7A
Other languages
English (en)
Chinese (zh)
Other versions
CN101910202A (zh
Inventor
斯特凡·马格拉夫
马丁·肖尔茨
延斯·阿尔特里克特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leukocare AG
Original Assignee
Leukocare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leukocare AG filed Critical Leukocare AG
Publication of CN101910202A publication Critical patent/CN101910202A/zh
Application granted granted Critical
Publication of CN101910202B publication Critical patent/CN101910202B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN200880124134.7A 2007-11-07 2008-11-07 用于固定生物物质的生物相容性三维基质 Expired - Fee Related CN101910202B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07021661.9A EP2058335B1 (en) 2007-11-07 2007-11-07 Biocompatible three dimensional matrix for the immobilization of biological substances
EP07021661.9 2007-11-07
PCT/EP2008/009417 WO2009059784A1 (en) 2007-11-07 2008-11-07 Biocompatible three dimensional matrix for the immobilization of biological substances

Publications (2)

Publication Number Publication Date
CN101910202A CN101910202A (zh) 2010-12-08
CN101910202B true CN101910202B (zh) 2016-11-09

Family

ID=39026695

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880124134.7A Expired - Fee Related CN101910202B (zh) 2007-11-07 2008-11-07 用于固定生物物质的生物相容性三维基质

Country Status (5)

Country Link
US (1) US20100291665A1 (enExample)
EP (1) EP2058335B1 (enExample)
JP (2) JP6058877B2 (enExample)
CN (1) CN101910202B (enExample)
WO (1) WO2009059784A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2236520A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Stabilizing composition for immobilized biomolecules
JP5402721B2 (ja) * 2010-03-01 2014-01-29 日立化成株式会社 検出装置及び検出方法
EP2726606A1 (en) 2011-06-28 2014-05-07 Leukocare Ag Novel stabilisation method for viruses or bacteria
DE102011051692A1 (de) * 2011-07-08 2013-01-10 Peter Brehm Chirurgie-Mechanik e.K. Verfahren zur Sterilisation von funktionalisierten, Nukleotide und/oder Nukleotidderivate enthaltenden, beschichteten Oberflächen
WO2014051141A1 (ja) * 2012-09-28 2014-04-03 積水メディカル株式会社 無希釈系イムノクロマトグラフ法試薬において希釈試料を測定するための添加物
EP2913671A1 (en) * 2014-02-27 2015-09-02 Leukocare Ag Novel coated carriers for the specific binding of target molecules
CN107531799B (zh) * 2015-04-13 2021-11-26 富士胶片株式会社 短链肽固定化载体的制造方法及短链肽固定化载体
EP3205261B1 (en) 2016-02-10 2018-03-28 Nokia Technologies Oy Intra-oral imaging
EP3210539B1 (en) * 2016-02-24 2019-09-11 Nokia Technologies Oy Intra-oral x-ray detection
EP3282254B1 (en) * 2016-08-12 2019-07-31 IST Austria (Institute of Science and Technology Austria) Method of producing a device for guided cell activation
CN109232952A (zh) * 2018-08-07 2019-01-18 广东元星工业新材料有限公司 一种聚氨酯制品表面处理方法
CN109187943B (zh) * 2018-08-24 2021-07-30 四川新健康成生物股份有限公司 一种抗干扰试剂杯以及试剂杯内抗干扰涂层的制备方法
JP6886668B2 (ja) * 2019-04-23 2021-06-16 住友ゴム工業株式会社 医療用検査装置及び細胞検査方法
CN110895283A (zh) * 2019-12-10 2020-03-20 宁波奥丞生物科技有限公司 一种高灵敏度的d-二聚体检测试剂盒及其使用方法
GB2631761A (en) * 2023-07-13 2025-01-15 Mykor Ltd Insulation

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760130A (en) * 1997-05-13 1998-06-02 Molecular Dynamics, Inc. Aminosilane/carbodiimide coupling of DNA to glass substrate
WO2001014425A1 (en) * 1999-08-19 2001-03-01 Diachip Limited Multipurpose diagnostic systems using protein chips
WO2001006011A3 (en) * 1999-07-14 2002-05-10 Genometrix Genomics Inc Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them
WO2002046756A1 (de) * 2000-11-17 2002-06-13 Zeptosens Ag Kit und verfahren zur multianalytbestimmung, mit vorkehrungen zur ortsaufgelösten referenzierung einer anregungslichtintensitaet
CN1371477A (zh) * 1999-07-05 2002-09-25 分子农业生物学院 用于检测兽类疾病的免疫诊断测试方法
CN1930283A (zh) * 2004-03-04 2007-03-14 白血球保健股份有限公司 白细胞刺激基体

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5426394A (en) * 1977-07-29 1979-02-27 Unitika Ltd Method for giving enzymatic activity to solic surface
JPS59204601A (ja) * 1983-05-09 1984-11-20 Unitika Ltd 生理活性を有する成形体の製造方法
JPS6187700A (ja) * 1984-10-05 1986-05-06 Shimadzu Corp ペプチド含有物質固定化物
CH663728A5 (fr) * 1985-06-10 1988-01-15 Battelle Memorial Institute Procede de purification de substances bioactives par adsorption biospecifique.
JPS63230088A (ja) * 1987-03-19 1988-09-26 Ngk Insulators Ltd 微生物固定化用担体
JPH01181790A (ja) * 1988-01-18 1989-07-19 Toray Silicone Co Ltd 生理活性物質の固定化方法
JPH07117519B2 (ja) * 1988-03-19 1995-12-18 株式会社堀場製作所 酵素固定膜の調製方法
JPH01317389A (ja) * 1988-06-17 1989-12-22 Tosoh Corp 生化学反応用担体およびその製造方法
US5077210A (en) * 1989-01-13 1991-12-31 Eigler Frances S Immobilization of active agents on substrates with a silane and heterobifunctional crosslinking agent
US5283034A (en) * 1989-06-29 1994-02-01 Applied Immune Sciences, Inc. Stabilization of sterilized surfaces for research and medical use
JPH0419561A (ja) * 1990-05-14 1992-01-23 Nippon Shokubai Co Ltd 免疫アッセイ用ブロッキング剤
JPH05219952A (ja) * 1992-02-14 1993-08-31 Tdk Corp 酵素固定用担体
JPH0759567A (ja) * 1993-08-24 1995-03-07 Toyobo Co Ltd 生理活性物質固定化用担体
US5674292A (en) * 1995-06-07 1997-10-07 Stryker Corporation Terminally sterilized osteogenic devices and preparation thereof
US6551794B1 (en) * 1995-11-09 2003-04-22 E. R. Squibb & Sons, Inc. Stable biotinylated biomolecule composition
US5691152A (en) * 1995-11-09 1997-11-25 E. R. Squibb & Sons, Inc. Stable avidin composition
EP0888779B1 (en) * 1996-02-05 2003-07-02 Asahi Medical Co., Ltd. Sterile protective agent and method for sterilization
JP4252123B2 (ja) * 1998-04-23 2009-04-08 ユニチカ株式会社 固定化線維素溶解活性酵素の活性安定化法
US20030012687A1 (en) * 2000-03-23 2003-01-16 Macphee Martin J. Methods of sterilizing biological materials
US20030124199A1 (en) * 2001-08-10 2003-07-03 Karl-Heinz Nietsch Use of fly larval extracts for wound treatment
US7252799B2 (en) * 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US6749851B2 (en) * 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
JP4189644B2 (ja) * 2003-01-15 2008-12-03 東洋紡績株式会社 生体分子相互作用測定方法
JP2005164348A (ja) * 2003-12-02 2005-06-23 Toyobo Co Ltd 生体分子相互作用観察方法
EP1852443A1 (en) * 2006-05-05 2007-11-07 Leukocare AG Biocompatible three dimensional matrix for the immobilization of biological substances

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760130A (en) * 1997-05-13 1998-06-02 Molecular Dynamics, Inc. Aminosilane/carbodiimide coupling of DNA to glass substrate
CN1371477A (zh) * 1999-07-05 2002-09-25 分子农业生物学院 用于检测兽类疾病的免疫诊断测试方法
WO2001006011A3 (en) * 1999-07-14 2002-05-10 Genometrix Genomics Inc Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them
WO2001014425A1 (en) * 1999-08-19 2001-03-01 Diachip Limited Multipurpose diagnostic systems using protein chips
WO2002046756A1 (de) * 2000-11-17 2002-06-13 Zeptosens Ag Kit und verfahren zur multianalytbestimmung, mit vorkehrungen zur ortsaufgelösten referenzierung einer anregungslichtintensitaet
CN1930283A (zh) * 2004-03-04 2007-03-14 白血球保健股份有限公司 白细胞刺激基体

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Carl Fredrik Mandenius等.The interaction of proteins and cells with affinity ligands covalently coupled to silicon surfaces as monitored by ellipsometry.《Analytical Biochemistry》.1984,第137卷(第1期),106-114. *
Jacob Piehler等.A high-density poly(ethylene glycol) polymer brush for immobilization on glass-type surfaces.《Biosensors and Bioelectronics》.2000,第15卷(第9-10期),473-481. *

Also Published As

Publication number Publication date
JP6058877B2 (ja) 2017-01-11
JP6898722B2 (ja) 2021-07-07
EP2058335A1 (en) 2009-05-13
CN101910202A (zh) 2010-12-08
US20100291665A1 (en) 2010-11-18
JP2011504169A (ja) 2011-02-03
JP2017061473A (ja) 2017-03-30
WO2009059784A1 (en) 2009-05-14
EP2058335B1 (en) 2020-06-24

Similar Documents

Publication Publication Date Title
CN101910202B (zh) 用于固定生物物质的生物相容性三维基质
CN101437853B (zh) 用于固定生物物质的生物相容性三维基体
EP3016729B1 (fr) Matrice de chromatographie d'affinité
Castilho et al. Comparison of affinity membranes for the purification of immunoglobulins
JPWO2014003137A1 (ja) 高アフィニティー抗体、及びその製造方法
Gustafsson et al. Protein–nanocellulose interactions in paper filters for advanced separation applications
US20140255409A1 (en) Method for extracorporeal elimination of one or more components from blood
CN101478998B (zh) 生物学液体处理用基材
CN103933947B (zh) 用于清除类风湿因子的血液净化材料及其制备方法
FR3008097A1 (fr) Matrice de chromatographie d'affinite
TW200927254A (en) Antibody production method
JP6259245B2 (ja) 免疫グロブリンＧに対する親和性を有するペプチド及びそれを用いたＩｇＧ型抗体吸着材
WO1988007892A1 (fr) Substance de separation de lymphocytes b et substance de clarification de fluides somatiques
US20140124448A1 (en) IMMUNOAFFINITY SEPARATION MATERIALS COMPRISING ANTI-IgE ANTIBODY DERIVATIVES
JPH01158970A (ja) 直接血液潅流用免疫グロブリン吸着材および吸着装置
JP6236278B2 (ja) 体液浄化デバイス用ＩｇＧ型抗体吸着材
JP6927259B2 (ja) 吸着材、カラム、精製装置及び吸着材の製造方法
JPS63252252A (ja) Ｂリンパ球分離材、分離方法および分離器
JP2006346096A (ja) 血液処理用基材

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information

Address after: German Madingsilide

Applicant after: LEUKOCARE AG

Address before: Munich, Germany

Applicant before: LEUKOCARE AG

CB02 Change of applicant information
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20161109

CF01 Termination of patent right due to non-payment of annual fee