WO2001006011A3 - Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them - Google Patents

Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them Download PDF

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Publication number
WO2001006011A3
WO2001006011A3 PCT/US2000/019045 US0019045W WO0106011A3 WO 2001006011 A3 WO2001006011 A3 WO 2001006011A3 US 0019045 W US0019045 W US 0019045W WO 0106011 A3 WO0106011 A3 WO 0106011A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
covalently associated
making
arrays
methods
Prior art date
Application number
PCT/US2000/019045
Other languages
French (fr)
Other versions
WO2001006011A2 (en
Inventor
Yuri Belosludtsev
Original Assignee
Genometrix Genomics Inc
Yuri Belosludtsev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genometrix Genomics Inc, Yuri Belosludtsev filed Critical Genometrix Genomics Inc
Priority to AU60933/00A priority Critical patent/AU6093300A/en
Publication of WO2001006011A2 publication Critical patent/WO2001006011A2/en
Publication of WO2001006011A3 publication Critical patent/WO2001006011A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides novel methods for making and using array-based nucleic acid hybridization substrates comprising non-covalently associated nucleic acids. The invention also provides nucleic acid arrays comprising a solid surface comprising a plurality of discrete biosites comprising a non-covalently associated nucleic acid. The invention also provides a method for determining if a nucleic acid in a test sample can hybridize to a nucleic acid immobilized onto an array.
PCT/US2000/019045 1999-07-14 2000-07-12 Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them WO2001006011A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU60933/00A AU6093300A (en) 1999-07-14 2000-07-12 Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14392699P 1999-07-14 1999-07-14
US60/143,926 1999-07-14

Publications (2)

Publication Number Publication Date
WO2001006011A2 WO2001006011A2 (en) 2001-01-25
WO2001006011A3 true WO2001006011A3 (en) 2002-05-10

Family

ID=22506299

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/019045 WO2001006011A2 (en) 1999-07-14 2000-07-12 Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them

Country Status (2)

Country Link
AU (1) AU6093300A (en)
WO (1) WO2001006011A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101910202B (en) * 2007-11-07 2016-11-09 白血球保健股份有限公司 Biocompatible three dimensional matrix for immobilization of biological substances

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1257354A2 (en) 2000-02-22 2002-11-20 Genospectra, Inc. Microarray fabrication techniques and apparatus
CN1416365A (en) 2000-02-22 2003-05-07 基因谱公司 Microarray fabrication tech and appts.
WO2002048404A2 (en) 2000-12-14 2002-06-20 Gen-Probe Incorporated Method and kit for enhancing the association rates of polynucleotides
US10272409B2 (en) * 2001-07-11 2019-04-30 Michael E. Hogan Methods and devices based upon a novel form of nucleic acid duplex on a surface
CA2656209C (en) * 2001-07-11 2012-11-27 Baylor College Of Medicine Methods and devices based upon a novel form of nucleic acid duplex on a surface
US7063978B2 (en) 2001-11-01 2006-06-20 3M Innovative Properties Company Coated film laminate having an electrically conductive surface
KR100700462B1 (en) * 2001-12-26 2007-03-29 캐논 가부시끼가이샤 Probe Medium
US20040054160A1 (en) * 2002-09-16 2004-03-18 Santona Pal Nucleic-acid ink compositions for arraying onto a solid support
US20050136413A1 (en) * 2003-12-22 2005-06-23 Briggs Michael W. Reagent systems for biological assays
KR100580644B1 (en) 2004-02-16 2006-05-16 삼성전자주식회사 A method for noncovalently immobilizing a biomolecule on a solid substrate and a microarray produced by the same
WO2006019116A1 (en) * 2004-08-17 2006-02-23 University Of Toyama Photoreactive compound, photoreactive polyamine and method for producing polyamine sheet
WO2008048355A2 (en) * 2006-02-27 2008-04-24 Genomics Usa Population scale hla-typing and uses thereof
EP1852443A1 (en) * 2006-05-05 2007-11-07 Leukocare AG Biocompatible three dimensional matrix for the immobilization of biological substances
US20090215050A1 (en) * 2008-02-22 2009-08-27 Robert Delmar Jenison Systems and methods for point-of-care amplification and detection of polynucleotides
US10731211B2 (en) * 2015-11-18 2020-08-04 Pacific Biosciences Of California, Inc. Methods and compositions for loading of polymerase complexes
CN109414408B (en) 2016-05-16 2022-03-29 得克萨斯州大学系统董事会 Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids
CN112481198A (en) * 2020-12-18 2021-03-12 宁波市博坤生物科技有限公司 Method for realizing separation of sperm cells of mixed spot inspection material based on polypeptide modified membrane

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996006948A1 (en) * 1994-08-30 1996-03-07 Beckman Instruments, Inc. Compositions and methods for use in detection of analytes
US5688642A (en) * 1994-12-01 1997-11-18 The United States Of America As Represented By The Secretary Of The Navy Selective attachment of nucleic acid molecules to patterned self-assembled surfaces
US5776694A (en) * 1990-10-19 1998-07-07 Becton Dickinson Company Diagnostic kits useful for selectively detecting microorganisms in samples

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776694A (en) * 1990-10-19 1998-07-07 Becton Dickinson Company Diagnostic kits useful for selectively detecting microorganisms in samples
WO1996006948A1 (en) * 1994-08-30 1996-03-07 Beckman Instruments, Inc. Compositions and methods for use in detection of analytes
US5688642A (en) * 1994-12-01 1997-11-18 The United States Of America As Represented By The Secretary Of The Navy Selective attachment of nucleic acid molecules to patterned self-assembled surfaces

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EISEN MICHAEL B ET AL: "DNA arrays for analysis of gene expression.", METHODS IN ENZYMOLOGY, vol. 303, 1999, 1999 Academic Press, Inc.; Academic Press Ltd. 1250 Sixth Ave., San Diego, California 92101, USA; 14 Belgrave Square, 24-28 Oval Road, London NW1 70X, England, UK, pages 179 - 205, XP000995864, ISBN: 0-12-182204-4 *
SCHENA M ET AL: "QUANTITATIVE MONITORING OF GENE EXPRESSION PATTERNS WITH A COMPLEMENTARY DNA MICROARRAY", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 270, no. 5235, 20 October 1995 (1995-10-20), pages 467 - 470, XP000644675, ISSN: 0036-8075 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101910202B (en) * 2007-11-07 2016-11-09 白血球保健股份有限公司 Biocompatible three dimensional matrix for immobilization of biological substances

Also Published As

Publication number Publication date
WO2001006011A2 (en) 2001-01-25
AU6093300A (en) 2001-02-05

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