CN101868465B - 包含N-(5-叔丁基-异噁唑-3-基)-N’-{4-[7-(2-吗啉-4-基-乙氧基)咪唑并[2，1-b][1，3]苯并噻唑-2-基]苯基}脲的固体形式、其组合物及其应用 - Google Patents

包含N-(5-叔丁基-异噁唑-3-基)-N’-{4-[7-(2-吗啉-4-基-乙氧基)咪唑并[2，1-b][1，3]苯并噻唑-2-基]苯基}脲的固体形式、其组合物及其应用 Download PDF

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CN101868465B
CN101868465B CN2008801167866A CN200880116786A CN101868465B CN 101868465 B CN101868465 B CN 101868465B CN 2008801167866 A CN2008801167866 A CN 2008801167866A CN 200880116786 A CN200880116786 A CN 200880116786A CN 101868465 B CN101868465 B CN 101868465B
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salt
certain embodiments
xrpd pattern
hcl salt
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CN101868465A (zh
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施里帕德·巴维特
赖伟
斯蒂芬·D·帕伦特
梅莱妮·J·罗
艾伦·施瓦兹
瓦勒莉雅·N·斯摩棱斯克
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Ambit Bioscience Corp
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CN2008801167866A 2007-09-19 2008-09-19 包含N-(5-叔丁基-异噁唑-3-基)-N’-{4-[7-(2-吗啉-4-基-乙氧基)咪唑并[2，1-b][1，3]苯并噻唑-2-基]苯基}脲的固体形式、其组合物及其应用 Active CN101868465B (zh)

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US99463507P 2007-09-19 2007-09-19
US60/994,635 2007-09-19
PCT/US2008/010884 WO2009038757A2 (en) 2007-09-19 2008-09-19 Solid forms comprising n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith

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CN101868465B true CN101868465B (zh) 2013-12-25

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