CN101787218B - 一类共轭链上β-位氮取代五甲川菁类荧光染料 - Google Patents
一类共轭链上β-位氮取代五甲川菁类荧光染料 Download PDFInfo
- Publication number
- CN101787218B CN101787218B CN201010010134.3A CN201010010134A CN101787218B CN 101787218 B CN101787218 B CN 101787218B CN 201010010134 A CN201010010134 A CN 201010010134A CN 101787218 B CN101787218 B CN 101787218B
- Authority
- CN
- China
- Prior art keywords
- dye
- dyestuff
- arh
- fluorescence
- cyanine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 CCC(C*(CCC*)C1)C1O Chemical compound CCC(C*(CCC*)C1)C1O 0.000 description 2
- TWYUZSDEYZKSDR-MEYOAXDGSA-N CCN(/C(/C1(C)C)=C/C=C/C(/C)=C/C2=[I]N(CC)c3ccccc3C2(C)C)c2c1cccc2 Chemical compound CCN(/C(/C1(C)C)=C/C=C/C(/C)=C/C2=[I]N(CC)c3ccccc3C2(C)C)c2c1cccc2 TWYUZSDEYZKSDR-MEYOAXDGSA-N 0.000 description 1
- FJBYBBNHCLILNP-JYRVWZFOSA-N CCN(C)c1c(C(C)C(C)CN(CC)C(/C=C\C)=C)cccc1 Chemical compound CCN(C)c1c(C(C)C(C)CN(CC)C(/C=C\C)=C)cccc1 FJBYBBNHCLILNP-JYRVWZFOSA-N 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0008—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain
- C09B23/0016—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain the substituent being a halogen atom
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0008—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain
- C09B23/0041—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain the substituent being bound through a nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
- C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
- C09B23/083—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines five >CH- groups
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
- C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1003—Carbocyclic compounds
- C09K2211/1007—Non-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1003—Carbocyclic compounds
- C09K2211/1011—Condensed systems
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1018—Heterocyclic compounds
- C09K2211/1025—Heterocyclic compounds characterised by ligands
- C09K2211/1029—Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
Claims (1)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010010134.3A CN101787218B (zh) | 2010-01-15 | 2010-01-15 | 一类共轭链上β-位氮取代五甲川菁类荧光染料 |
PCT/CN2010/001971 WO2011085532A1 (zh) | 2010-01-15 | 2010-12-06 | 一类共轭链上β-位氮取代五甲川菁类荧光染料 |
US13/521,046 US8735601B2 (en) | 2010-01-15 | 2010-12-06 | Pentamethine cyanine fluorescent dye with N-substituting at β-position of conjugated chain |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010010134.3A CN101787218B (zh) | 2010-01-15 | 2010-01-15 | 一类共轭链上β-位氮取代五甲川菁类荧光染料 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101787218A CN101787218A (zh) | 2010-07-28 |
CN101787218B true CN101787218B (zh) | 2014-04-02 |
Family
ID=42530601
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201010010134.3A Expired - Fee Related CN101787218B (zh) | 2010-01-15 | 2010-01-15 | 一类共轭链上β-位氮取代五甲川菁类荧光染料 |
Country Status (3)
Country | Link |
---|---|
US (1) | US8735601B2 (zh) |
CN (1) | CN101787218B (zh) |
WO (1) | WO2011085532A1 (zh) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120214193A1 (en) * | 2009-10-30 | 2012-08-23 | Keio University | Method for measurement of fluorescence intensity of voltage-sensitive fluorescent dye |
WO2012103678A1 (zh) * | 2011-01-31 | 2012-08-09 | 大连理工大学 | 一类五甲川菁荧光染料、制备方法及其应用 |
CN102618060A (zh) * | 2012-03-17 | 2012-08-01 | 江南大学 | 一种不对称菁染料的制备及其用于牛血清白蛋白检测的方法 |
EP3170004B1 (en) | 2014-07-15 | 2020-08-12 | Valitacell Limited | A method of measuring antibody concentration in a sample |
CN105885466A (zh) * | 2014-12-17 | 2016-08-24 | 付义乐 | 一种一甲川菁染料的合成方法 |
CN105111773B (zh) * | 2015-08-19 | 2017-06-27 | 大连理工大学 | 一类氨基菁类荧光染料及其制备方法和应用 |
CN105670334B (zh) * | 2016-02-29 | 2017-10-10 | 华东师范大学 | 一种葡萄糖基化近红外染料及其制备方法和应用 |
CN106188191A (zh) * | 2016-07-13 | 2016-12-07 | 西安电子科技大学 | 基于gsh响应的诊治一体化有机分子探针及其制备方法 |
CN108624081B (zh) * | 2018-05-29 | 2020-03-10 | 苏州百源基因技术有限公司 | 一种荧光染料及其制备方法与应用 |
CN109180693A (zh) * | 2018-09-10 | 2019-01-11 | 苏州健雄职业技术学院 | 螺吡喃和螺噁嗪类化合物及其制备方法 |
WO2020086691A1 (en) | 2018-10-24 | 2020-04-30 | California Institute Of Technology | Near-infrared heptamethine dyes for generation of singlet oxygen |
CN112940520B (zh) * | 2019-12-10 | 2023-03-31 | 中国科学院大连化学物理研究所 | 一类具有细胞器定位性质的荧光染料在细胞器成像中的应用 |
CN111560026B (zh) * | 2020-05-11 | 2021-08-27 | 苏州大学 | 高光学稳定性细胞膜荧光标记物及其制备方法与应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB620801A (en) * | 1947-01-24 | 1949-03-30 | Frank Peter Doyle | Improvements in or relating to cyanine dyestuffs |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2235463B (en) * | 1989-08-23 | 1992-04-29 | Ilford Ltd | Photographic emulsions containing pentamethine cyanine dyes |
JPH04283269A (ja) * | 1991-03-11 | 1992-10-08 | Sanyo Electric Co Ltd | シアニン色素誘導体及び光記録媒体 |
JP2001348500A (ja) * | 1999-04-27 | 2001-12-18 | Hayashibara Biochem Lab Inc | シアニン色素 |
JP4986457B2 (ja) * | 2005-04-05 | 2012-07-25 | 株式会社Adeka | シアニン化合物、光学フィルター及び光学記録材料 |
-
2010
- 2010-01-15 CN CN201010010134.3A patent/CN101787218B/zh not_active Expired - Fee Related
- 2010-12-06 WO PCT/CN2010/001971 patent/WO2011085532A1/zh active Application Filing
- 2010-12-06 US US13/521,046 patent/US8735601B2/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB620801A (en) * | 1947-01-24 | 1949-03-30 | Frank Peter Doyle | Improvements in or relating to cyanine dyestuffs |
Non-Patent Citations (3)
Title |
---|
JP特开2001-348500A 2001.12.18 |
JP特开平4-283269A 1992.10.08 |
O. Przhonska et al..Investigation of excited-state relaxation processes of organic dyes by time-resolved spectroscopy.《AIP Conference Proceedings》.1996,第364卷197-203. * |
Also Published As
Publication number | Publication date |
---|---|
WO2011085532A1 (zh) | 2011-07-21 |
US20120296098A1 (en) | 2012-11-22 |
CN101787218A (zh) | 2010-07-28 |
US8735601B2 (en) | 2014-05-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101787218B (zh) | 一类共轭链上β-位氮取代五甲川菁类荧光染料 | |
CN102146215B (zh) | 一类五甲川菁荧光染料、制备方法及其应用 | |
US7709653B2 (en) | Asymmetric cyanine compounds, their preparation methods and their uses | |
CN103059832B (zh) | 一类近红外荧光探针化合物及其制备方法、应用 | |
CN100473653C (zh) | 生物分析用近红外中位氮、硫七甲川菁类荧光染料 | |
CN101723874B (zh) | 花菁类化合物及其在生物样品染色中的用途 | |
EP1078023A1 (en) | Luminescent compounds | |
CN103087545A (zh) | 一类以荧光素为母体的荧光染料、其制备方法及应用 | |
CN108864056B (zh) | 具有aie性能的近红外荧光化合物及其制备方法和应用 | |
CN102618060A (zh) | 一种不对称菁染料的制备及其用于牛血清白蛋白检测的方法 | |
Zhang et al. | Synthesis, spectral properties of cell-permeant dimethine cyanine dyes and their application as fluorescent probes in living cell imaging and flow cytometry | |
CN110256218A (zh) | 一种聚集诱导发光染料分子及其合成方法 | |
CN1939978B (zh) | 水溶性荧光菁染料 | |
CN108504130A (zh) | 一种花菁类荧光染料及其合成方法 | |
CN105440725A (zh) | 不对称菁类荧光染料,组合物及在生物样品染色中的用途 | |
Li et al. | Turn-on and blue-shift fluorescence sensor toward l-histidine based on stable Cd II metal–organic framework with tetranuclear cluster units | |
CN101555246A (zh) | 含卤素不对称菁类化合物、制备方法及应用 | |
JP2016196447A (ja) | 発蛍光性化合物又はその塩、イオン性化合物の検出剤及びイオン性化合物の検出方法 | |
JP6709734B2 (ja) | アルコキシシリル基含有有機el色素およびその製造方法 | |
CN108516979B (zh) | 一种基于萘酰亚胺-罗丹明的化合物及其应用 | |
CN107814796A (zh) | 一种基于苯并呋咱的环境敏感染料及其制备方法和应用 | |
CN102964863B (zh) | 吲哚类半菁染料的合成与应用 | |
Terpetschnig et al. | Luminescent probes for NIR sensing applications | |
CN102391162A (zh) | 三种基于铕(III)与氯磺酰化四齿β-二酮配位体形成的荧光配合物及其应用 | |
CN109503550A (zh) | 2-氮杂芳基-6-取代氨基喹唑啉酮化合物及其制备方法和应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract | ||
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20100728 Assignee: DALIAN FUSIDA SPECIAL CHEMICAL Co.,Ltd. Assignor: Dalian University of Technology Contract record no.: 2017210000009 Denomination of invention: Conjugated chain beta-N-substituted cyanine fluorescent dye Granted publication date: 20140402 License type: Common License Record date: 20170331 Application publication date: 20100728 Assignee: DALIAN CHROMAS BIOSCIENCE Co.,Ltd. Assignor: Dalian University of Technology Contract record no.: 2017210000008 Denomination of invention: Conjugated chain beta-N-substituted cyanine fluorescent dye Granted publication date: 20140402 License type: Common License Record date: 20170331 |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140402 Termination date: 20220115 |