CN101596186A - 抗癌组合 - Google Patents

抗癌组合 Download PDF

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Publication number
CN101596186A
CN101596186A CNA2009101604099A CN200910160409A CN101596186A CN 101596186 A CN101596186 A CN 101596186A CN A2009101604099 A CNA2009101604099 A CN A2009101604099A CN 200910160409 A CN200910160409 A CN 200910160409A CN 101596186 A CN101596186 A CN 101596186A
Authority
CN
China
Prior art keywords
topoisomerase
inhibitor
chemical compound
antimetabolite
anthracycline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2009101604099A
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English (en)
Chinese (zh)
Inventor
W.R.威尔逊
B.G.西姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cancer Research Technology Ltd
Original Assignee
Cancer Research Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Technology Ltd filed Critical Cancer Research Technology Ltd
Publication of CN101596186A publication Critical patent/CN101596186A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CNA2009101604099A 2001-09-03 2002-09-03 抗癌组合 Pending CN101596186A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0121285.1 2001-09-03
GBGB0121285.1A GB0121285D0 (en) 2001-09-03 2001-09-03 Anti-cancer combinations

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB028172574A Division CN100536840C (zh) 2001-09-03 2002-09-03 抗癌组合

Publications (1)

Publication Number Publication Date
CN101596186A true CN101596186A (zh) 2009-12-09

Family

ID=9921418

Family Applications (5)

Application Number Title Priority Date Filing Date
CNA2009101604099A Pending CN101596186A (zh) 2001-09-03 2002-09-03 抗癌组合
CNA2006101513931A Pending CN1994287A (zh) 2001-09-03 2002-09-03 抗癌组合
CNA2009101604101A Pending CN101596187A (zh) 2001-09-03 2002-09-03 抗癌组合
CNA2009101604084A Pending CN101607087A (zh) 2001-09-03 2002-09-03 抗癌组合
CNB028172574A Expired - Fee Related CN100536840C (zh) 2001-09-03 2002-09-03 抗癌组合

Family Applications After (4)

Application Number Title Priority Date Filing Date
CNA2006101513931A Pending CN1994287A (zh) 2001-09-03 2002-09-03 抗癌组合
CNA2009101604101A Pending CN101596187A (zh) 2001-09-03 2002-09-03 抗癌组合
CNA2009101604084A Pending CN101607087A (zh) 2001-09-03 2002-09-03 抗癌组合
CNB028172574A Expired - Fee Related CN100536840C (zh) 2001-09-03 2002-09-03 抗癌组合

Country Status (23)

Country Link
US (6) US7863322B2 (enExample)
EP (3) EP1423105B9 (enExample)
JP (3) JP2005509599A (enExample)
CN (5) CN101596186A (enExample)
AT (1) ATE415963T1 (enExample)
AU (1) AU2002324143B2 (enExample)
BR (1) BR0212258A (enExample)
CA (1) CA2458459A1 (enExample)
CY (1) CY1110426T1 (enExample)
DE (1) DE60230159D1 (enExample)
DK (1) DK1423105T3 (enExample)
EA (3) EA008056B1 (enExample)
ES (1) ES2321283T3 (enExample)
GB (1) GB0121285D0 (enExample)
IL (1) IL160178A0 (enExample)
IS (1) IS7144A (enExample)
MX (1) MXPA04002004A (enExample)
NO (1) NO20040591L (enExample)
NZ (5) NZ567456A (enExample)
PT (1) PT1423105E (enExample)
SI (1) SI1423105T1 (enExample)
WO (1) WO2003020259A2 (enExample)
ZA (1) ZA200401078B (enExample)

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Also Published As

Publication number Publication date
NZ576925A (en) 2010-07-30
US20040204480A1 (en) 2004-10-14
JP2010270124A (ja) 2010-12-02
EP1423105A2 (en) 2004-06-02
CA2458459A1 (en) 2003-03-13
CY1110426T1 (el) 2015-04-29
US20080070847A1 (en) 2008-03-20
MXPA04002004A (es) 2005-02-17
US20070060637A1 (en) 2007-03-15
EA010857B1 (ru) 2008-12-30
US20080070886A1 (en) 2008-03-20
NZ531045A (en) 2006-08-31
AU2002324143B2 (en) 2007-09-13
DE60230159D1 (de) 2009-01-15
EP1759694A2 (en) 2007-03-07
BR0212258A (pt) 2004-10-19
EP1423105B1 (en) 2008-12-03
US7868039B2 (en) 2011-01-11
EA200801611A1 (ru) 2009-06-30
CN101607087A (zh) 2009-12-23
JP2009263371A (ja) 2009-11-12
EA200601118A1 (ru) 2006-12-29
CN1994287A (zh) 2007-07-11
IS7144A (is) 2004-02-06
GB0121285D0 (en) 2001-10-24
EA200400370A1 (ru) 2004-08-26
WO2003020259A3 (en) 2003-04-17
WO2003020259A2 (en) 2003-03-13
US20080070848A1 (en) 2008-03-20
SI1423105T1 (sl) 2009-08-31
EP1423105B9 (en) 2009-08-12
NZ567456A (en) 2009-08-28
EP2236134A1 (en) 2010-10-06
ES2321283T3 (es) 2009-06-04
NO20040591L (no) 2004-04-30
EA008056B1 (ru) 2007-02-27
CN101596187A (zh) 2009-12-09
US20080070849A1 (en) 2008-03-20
US7863322B2 (en) 2011-01-04
NZ554093A (en) 2008-07-31
DK1423105T3 (da) 2009-03-30
EP1759694A3 (en) 2009-02-18
US7863320B2 (en) 2011-01-04
US7868040B2 (en) 2011-01-11
US7863321B2 (en) 2011-01-04
NZ546573A (en) 2007-05-31
ZA200401078B (en) 2005-04-15
ATE415963T1 (de) 2008-12-15
JP2005509599A (ja) 2005-04-14
CN100536840C (zh) 2009-09-09
PT1423105E (pt) 2009-03-09
CN1708296A (zh) 2005-12-14
IL160178A0 (en) 2004-07-25

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