CN101420977B - Nogo受体拮抗剂 - Google Patents

Nogo受体拮抗剂 Download PDF

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Publication number
CN101420977B
CN101420977B CN200780010338.3A CN200780010338A CN101420977B CN 101420977 B CN101420977 B CN 101420977B CN 200780010338 A CN200780010338 A CN 200780010338A CN 101420977 B CN101420977 B CN 101420977B
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polypeptide
seq
amino acid
antibody
antibodies
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Chinese (zh)
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CN101420977A (zh
Inventor
丹尼尔·H·S·李
文丁
文丁一
R·布莱克·佩平斯凯
K·简·雷尔顿
王辛中
阿列克谢·卢戈夫斯科伊
沃纳·迈尔
埃伦·A·加伯
劳拉·西尔维安
保罗·H·魏因雷布
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Biogen MA Inc
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Biogen Idec MA Inc
Biogen MA Inc
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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CN200780010338.3A 2006-01-27 2007-01-26 Nogo受体拮抗剂 Active CN101420977B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201210593895.5A CN103215293B (zh) 2006-01-27 2007-01-26 Nogo受体拮抗剂

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Application Number Priority Date Filing Date Title
US76248706P 2006-01-27 2006-01-27
US60/762,487 2006-01-27
US83165906P 2006-07-19 2006-07-19
US60/831,659 2006-07-19
PCT/US2007/002199 WO2007089601A2 (en) 2006-01-27 2007-01-26 Nogo receptor antagonists

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CN101420977A CN101420977A (zh) 2009-04-29
CN101420977B true CN101420977B (zh) 2016-08-10

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US (3) US8669345B2 (enExample)
EP (2) EP2526968A3 (enExample)
JP (4) JP5829373B2 (enExample)
CN (2) CN101420977B (enExample)
BR (1) BRPI0707276B1 (enExample)
CA (2) CA2913655A1 (enExample)
DK (1) DK1981902T3 (enExample)
ES (1) ES2550099T3 (enExample)
HR (1) HRP20151108T1 (enExample)
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Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2526968A3 (en) * 2006-01-27 2013-05-22 Biogen Idec MA Inc. Nogo receptor antagonists
WO2009114197A2 (en) 2008-03-13 2009-09-17 Yale University Reactivation of axon growth and recovery in chronic spinal cord injury
CN103328633B (zh) * 2010-10-22 2018-07-10 成均馆大学校产学协力团 诱导rna干扰的核酸分子及其用途
ES2923757T3 (es) * 2011-12-16 2022-09-30 Modernatx Inc Composiciones de ARNm modificado
WO2013151664A1 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
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